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Outpatient penicillin skin testing has greater value in targeted patient populations
β-Lactam allergy is a major component of antimicrobial stewardship today due to its reported associations with increased healthcare costs, drug toxicity, infections with drug-resistant bacteria, and use of less-preferred antibiotic therapies.1,2 It remains the most common reported medication allerg y in the United States, with an estimated prevalence of 10%.1 The US Centers for Disease Control and Prevention and the Infectious Disease Society of America, among other institutions, recommend the performance of penicillin skin testing (PST) as part of antimicrobial stewardship.
Source: Annals of Allergy, Asthma and Immunology - April 1, 2018 Category: Allergy & Immunology Authors: Viviana M. Temi ño, Timothy P. Gauthier, Paola Lichtenberger Source Type: research
Common questions in food allergy avoidance
Food allergies affect up to 5% to 8% of children in the United States1,2 and may be increasing in prevalence3 as evidenced by a report from the Centers for Disease Control and Prevention, which noted a 50% increase in the United States between 1997 and 2011.4 Although many foods have been reported to trigger allergic reactions, the most common causes of significant allergic reactions are milk, egg, wheat, soy, peanut, tree nuts, fish, shellfish, and seeds.5 Although treatment options for food allergies, such as oral and epicutaneous immunotherapy, have shown potential, they are not currently approved for general use by the...
Source: Annals of Allergy, Asthma and Immunology - March 1, 2018 Category: Allergy & Immunology Authors: Maureen Egan, Matthew Greenhawt Tags: MOC-CME Review Source Type: research
Why Flu Outbreaks Have Been the Worst in Nearly a Decade
The only thing worse than getting the flu is catching it after you’ve gotten a flu shot. It’s been a terrible year for outbreaks — the worst in almost a decade. Contributing to that is the high failure rate of this year’s vaccine. The current shot is just 25 percent effective against the H3N2 virus, this season’s most-often-identified strain by the Centers for Disease Control and Prevention. The experts say, with enough time and money, they can do a lot better.
“There has to be a wholesale change to how we make the flu vaccine,” said Amesh Adalja, senior scholar at Johns Hopkins Ce...
Source: TIME: Science - February 28, 2018 Category: Science Authors: Bloomberg Tags: Uncategorized Bloomberg flu healthytime onetime Source Type: news
Migration and risk of HIV acquisition in Rakai, Uganda: a population-based cohort study
Publication date: Available online 25 February 2018 Source:The Lancet HIV Author(s): Oluwasolape Olawore, Aaron A R Tobian, Joseph Kagaayi, Jeremiah M Bazaale, Betty Nantume, Grace Kigozi, Justine Nankinga, Fred Nalugoda, Gertrude Nakigozi, Godfrey Kigozi, Ronald H Gray, Maria J Wawer, Robert Ssekubugu, John S Santelli, Steven J Reynolds, Larry W Chang, David Serwadda, Mary K Grabowski Background In sub-Saharan Africa, migrants typically have higher HIV prevalence than non-migrants; however, whether HIV acquisition typically precedes or follows migration is unknown. We aimed to investigate the risk of HIV after migration ...
Source: The Lancet HIV - February 26, 2018 Category: Infectious Diseases Source Type: research
Experts Concerned About Effectiveness Of This Year ’ s Flu Vaccine
(CNN) — Last year’s seasonal flu vaccine effectiveness was just 42%, the US Centers for Disease Control and Prevention estimated. Even if vaccinated, people had inadequate protection against the flu.
This limited effectiveness was due to a mutation that occurred in the influenza A (H3N2) vaccine strain, according to a study published Monday in the journal Proceedings of the National Academy of Sciences. This vaccine mutation resulted from an egg-based manufacturing process commonly used today.
This year’s flu vaccine may also be imperfect, said Scott Hensley, author of the new study and an associate profe...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - November 8, 2017 Category: Consumer Health News Authors: Health – CBS Boston Tags: Health News Flu Flu Vaccine Local TV Source Type: news
Mortality rate for people with lupus remains higher than U.S. rate overall
FINDINGSWhile the mortality rate in the United States have declined over the past four decades, UCLA researchers found that the mortality rate for people with lupus has not declined as much as it has for the population overall.The researchers found that among people with lupus, mortality rates are still higher for black people than for other ethnicities; rates for women are higher than those of men; and those in the South were higher than for other regions of the U.S. Mortality rates for people with lupus were affected by where they lived.BACKGROUNDLupus is a chronic disease in which the immune system attacks the body ’s...
Source: UCLA Newsroom: Health Sciences - November 1, 2017 Category: Universities & Medical Training Source Type: news
Warm, Cozy Woodstoves . . . and the PM They Produce: Home Interventions Show Mixed Results in Protecting Children with Asthma
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Published: 17 October 2017
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Source: EHP Research - October 17, 2017 Category: Environmental Health Authors: Daniil Lyalko Tags: Science Selection Source Type: research
Understanding the biology of disease in underserved children with asthma
African American children are disproportionately affected by asthma compared with non-Hispanic white children. Recent data from the Centers for Disease Control and Prevention indicate that asthma prevalence rates (10.3% vs 7.8%) remain higher among non-Hispanic black children than non-Hispanic white children, and non-Hispanic black children are almost 3 times as likely to die of asthma as non-Hispanic white children.1 Studies have also found that African American children have more frequent and burdensome asthma symptoms and use emergency department (ED) care more frequently than white children.
Source: Annals of Allergy, Asthma and Immunology - August 1, 2017 Category: Allergy & Immunology Authors: Bridgette L. Jones Tags: Guest Editorial Source Type: research
FDA Science: Working at the speed of emerging technologies
FDA Acting Chief Scientist Luciana Borio
By Luciana Borio, M.D.
Let’s face it, we’ve all gotten used to nearly instant access to almost anything.
Today, with a tap of an app, we order a car ride, a book, or pizza for dinner. Need to navigate past traffic in downtown city streets? No problem. There’s an app for that, too.
Some may wonder: Why hasn’t rapid medical product development partaken of this need for speed that has reshaped other sectors of our economy? Well, in many ways, it has.
Innovation is happening extraordinarily fast in the biomedical sciences and at FDA. As FDA’s Acting Chief Scientist responsible...
Source: Mass Device - June 22, 2017 Category: Medical Devices Authors: Danielle Kirsh Tags: Blog FDA Voice Source Type: news
Oh, Lovely: The Tick That Gives People Meat Allergies Is Spreading
By Megan Molteni for WIRED.
First comes the unscratchable itching, and the angry blossoming of hives. Then stomach cramping, and — for the unluckiest few — difficulty breathing, passing out, and even death. In the last decade and a half, thousands of previously protein-loving Americans have developed a dangerous allergy to meat. And they all have one thing in common: the lone star tick.
Red meat, you might be surprised to know, isn’t totally sugar-free. It contains a few protein-linked saccharides, including one called galactose-alpha-1,3-galactose, or alpha-gal, for short. More and more people are lear...
Source: Healthy Living - The Huffington Post - June 20, 2017 Category: Consumer Health News Source Type: news
The Florence Statement on Triclosan and Triclocarban
Author Affiliations open
1Biodesign Center for Environmental Security, Arizona State University, Tempe, Arizona, USA
2Green Science Policy Institute, Berkeley, California, USA
3Department of Epidemiology, UNC Gillings School of Global Public Health, University of North Carolina, Chapel Hill, North Carolina, USA
4Environmental Working Group, Washington, District of Columbia, USA
5Department of Civil, Environmental, and Geo-Engineering, University of Minnesota, Minneapolis, Minnesota, USA
6Medical University of South Carolina, Department of Public Health Sciences, Charleston, South Carolina, USA
7Health Research Communicati...
Source: EHP Research - June 20, 2017 Category: Environmental Health Authors: Daniil Lyalko Tags: Brief Communication Source Type: research
At Least 1 Person Dead From New Ebola Outbreak In Democratic Republic Of Congo
One person has died from a new outbreak of the Ebola virus in the Democratic Republic of Congo, the World Health Organization confirmed Friday.
The country has reported nine suspected cases of the virus and three deaths since April 22, according to WHO communications officer Christoper Lindmeier. Out of the three deaths, one tested positive for Ebola.
The #Ebola case in the Democratic Republic of Congo was confirmed by a national reference laboratory in Kinshasa #DRC— WHO (@WHO) May 12, 2017
The cases were discovered in Aketi, a remote region without much access to health facilities, WHO communications offi...
Source: Science - The Huffington Post - May 12, 2017 Category: Science Source Type: news
The World Is Not Ready for the Next Pandemic
Across China, the virus that could spark the next pandemic is already circulating. It’s a bird flu called H7N9, and true to its name, it mostly infects poultry. Lately, however, it’s started jumping from chickens to humans more readily–bad news, because the virus is a killer. During a recent spike, 88% of people infected got pneumonia, three-quarters ended up in intensive care with severe respiratory problems, and 41% died.
What H7N9 can’t do–yet–is spread easily from person to person, but experts know that could change. The longer the virus spends in humans, the better the chance that i...
Source: TIME.com: Top Science and Health Stories - May 4, 2017 Category: Consumer Health News Authors: Bryan Walsh Tags: Uncategorized CDC Disease ebola Gates Foundation MERS outbreak pandemic Zika Source Type: news
Scientists Start Second Phase Of Zika Vaccine Testing
Researchers at Houston’s Baylor College of Medicine last week began Phase 2 clinical trials for a Zika vaccine that is expected to have results as early as the end of this year.
Andrew Pekosz, a professor of microbiology and immunology at Johns Hopkins University’s Bloomberg School of Public Health, praised the vaccine’s potential to prevent disease, as well as how quickly clinical trials have taken place.
“It’s really been a light-speed endeavor,” Pekosz, who was not involved in the vaccine’s testing or development at the National Institute for Allergy and In...
Source: Science - The Huffington Post - April 3, 2017 Category: Science Source Type: news
