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Infectious Disease: Outbreaks

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Total 533 results found since Jan 2013.

Emergence of Marburg virus: a global perspective on fatal outbreaks and clinical challenges
The Marburg virus (MV), identified in 1967, has caused deadly outbreaks worldwide, the mortality rate of Marburg virus disease (MVD) varies depending on the outbreak and virus strain, but the average case fatality rate is around 50%. However, case fatality rates have varied from 24 to 88% in past outbreaks depending on virus strain and case management. Designated a priority pathogen by the National Institute of Allergy and Infectious Diseases (NIAID), MV induces hemorrhagic fever, organ failure, and coagulation issues in both humans and non-human primates. This review presents an extensive exploration of MVD outbreak evolu...
Source: Frontiers in Microbiology - September 13, 2023 Category: Microbiology Source Type: research

An outbreak of anaphylactic transfusion reactions to group B plasma and platelets and its possible relationship to Alpha-Gal syndrome
DISCUSSION: AGS is an emerging problem which may have implications for blood transfusion practice. Avoidance of blood group B antigen containing components may be prudent in non-blood group B patients with established AGS. Investigation for AGS should be considered in the evaluation of anaphylactic transfusion reactions.PMID:37642435 | DOI:10.1111/trf.17521
Source: Transfusion - August 29, 2023 Category: Hematology Authors: Colleen W Gilstad Kathleen Conry-Cantilena Roya Zarpak Anne F Eder Source Type: research

Senate panel approves 2% bump for NIH budget in 2024
To the relief of biomedical research advocates, a Senate spending panel has approved a modest budget increase of 2% for the National Institutes of Health (NIH). The bump to $47.8 billion roughly matches President Joe Biden’s request for the 2024 fiscal year that begins this fall. Although below the rate of biomedical inflation, it is far more generous than a corresponding House of Representatives bill that would slash NIH’s budget by 6% . Advocacy groups welcomed the measure approved on 27 July by the Senate appropriations committee. “The Committee laid down an important marker for the appropriations...
Source: Science of Aging Knowledge Environment - July 28, 2023 Category: Geriatrics Source Type: research

Politicians, scientists spar over alleged NIH cover-up using COVID-19 origin paper
Two scientists who are coauthors of a 3-year-old article on the origin of the COVID-19 pandemic faced down Republican lawmakers today in what might be the most in-depth discussion ever of a scientific paper in the halls of the U.S. Congress. At a House subcommittee hearing , the Republicans asserted that top officials at the U.S. National Institutes of Health (NIH) prompted the researchers to write the paper to try and “kill” the theory that SARS-CoV-2 leaked from a laboratory in Wuhan, China. The scientists, two of its five co-authors, flatly rejected the allegation. And as the hearing extended over 3 hours, com...
Source: Science of Aging Knowledge Environment - July 11, 2023 Category: Geriatrics Source Type: research

The U.S. Scientist At the Heart of COVID-19 Lab Leak Conspiracies Is Still Trying to Save the World From the Next Pandemic
Ralph Baric stepped onto the auditorium stage at the University of North Carolina, Chapel Hill, and looked out at the sparse audience that had come to hear him speak. On the large projector screen hanging behind him, the following words appeared: How Bad the Next Pandemic Could Be, What Might It Look Like, and Will We be Ready. The date was May 29, 2018. “Well, I have to admit I’m a little worried about giving this talk,” Baric said. “The reason is being labelled a harbinger of doom.” The screen shifted, and images of the four horsemen of the apocalypse—Death, Famine, War, and Plague&mda...
Source: TIME: Health - July 11, 2023 Category: Consumer Health News Authors: Dan Werb Tags: Uncategorized COVID-19 feature freelance Source Type: news

The Conspirituality of Robert F. Kennedy Jr.
This article has been adapted from Chapter 23 of Conspirituality: How New Age Conspiracy Theories Became a Health Threat by Derek Beres, Matthew Remski, and Julian Walker. Copyright © 2023. Available from PublicAffairs, an imprint of Hachette Book Group, Inc.
Source: TIME: Health - July 5, 2023 Category: Consumer Health News Authors: Derek Beres, Matthew Remski, and Julian Walker Tags: Uncategorized freelance politics Source Type: news

NIH restarts bat virus grant suspended 3 years ago by Trump
Three years after then-President Donald Trump pressured the National Institutes of Health (NIH) to suspend a research grant to a U.S. group studying bat coronaviruses with partners in China, the agency has restarted the award. The new 4-year grant is a stripped-down version of the original grant to the EcoHealth Alliance, a nonprofit research organization in New York City, providing $576,000 per year. That 2014 award included funding for controversial experiments that mixed parts of different bat viruses related to severe acute respiratory syndrome (SARS), the coronavirus that sparked a global outbreak in 2002–04, a...
Source: ScienceNOW - May 8, 2023 Category: Science Source Type: news

Tetanus, diphtheria, and acellular pertussis (Tdap) vaccine coverage in adults with chronic respiratory conditions
Pertussis is a highly contagious, vaccine-preventable, respiratory disease caused by the bacterium Bordetella pertussis. Despite high infant vaccination rates and the extension of vaccine recommendations to adolescents and adults, the control of pertussis has proven challenging. Pertussis has remained endemic world-wide and upward trends in incidence, with increased intensity of outbreaks, have been documented in multiple countries.1-5 Although most cases of pertussis occur among infants too young to be vaccinated, the global change in the epidemiology of pertussis has been accompanied by a gradual shift in the age-specifi...
Source: Annals of Allergy, Asthma and Immunology - April 18, 2023 Category: Allergy & Immunology Authors: Sarah Naeger, Denis Macina, Vitali Pool Tags: Original Article Source Type: research

Scientists Laud $5B ' Project Next Gen ' to Fund New COVID Vaccines Scientists Laud $5B ' Project Next Gen ' to Fund New COVID Vaccines
The federal program has yet to be formally announced, but pandemic experts say it is a much needed boost to taming COVID and combating future coronavirus outbreaks.Medscape Medical News
Source: Medscape Allergy Headlines - April 13, 2023 Category: Allergy & Immunology Tags: Infectious Diseases News Source Type: news

Deadly parasite threatens California sea otters
Melissa Miller knew something was off when she began to examine a sea otter that had died in San Simeon, a coastal California town about halfway between San Francisco and Los Angeles, in the winter of 2020. Nearly all of the animal’s body fat was inflamed. “It felt like there were little bumps all through it,” she says—a condition the veterinary pathologist had never seen in her 25 years examining sea otters for the California Department of Fish and Wildlife. She also found unusual lesions in the pancreas and heart. When Miller looked at the sea otter’s tissues under a microscope, she spotted a familiar foe:...
Source: ScienceNOW - March 22, 2023 Category: Science Source Type: news

Case studies expose deadly risk of mpox to people with untreated HIV
In June 2022, a young man in his 30s severely sick with mpox, the viral disease formerly known as monkeypox, was admitted to the Salvador Zubirán National Institute of Health Sciences and Nutrition hospital in Mexico City. Tests showed the patient was also HIV-positive, which he had not known, and that his blood had few CD4 cells, critical immune cells that HIV attacks. The man’s immune system was so weak it could not keep mpox in check and painful lesions kept spreading across his body, eating away at, or necrotizing, the flesh, according to HIV researcher Brenda Crabtree Ramirez, who was on his care team. Then the vir...
Source: Science of Aging Knowledge Environment - February 21, 2023 Category: Geriatrics Source Type: research

Case studies expose deadly risk of mpox in people with untreated HIV
In June 2022, a young man in his 30s severely sick with mpox, the viral disease formerly known as monkeypox, was admitted to the Salvador Zubirán National Institute of Health Sciences and Nutrition hospital in Mexico City. Tests showed the patient was also HIV-positive, which he had not known, and that his blood had few CD4 cells, critical immune cells that HIV attacks. The man’s immune system was so weak it could not keep mpox in check and painful lesions kept spreading across his body, eating away at, or necrotizing, the flesh, according to HIV researcher Brenda Crabtree Ramirez, who was on his care team. Then the vir...
Source: ScienceNOW - February 21, 2023 Category: Science Source Type: news

Decreased pollen sensitization in school-age children after the COVID-19 pandemic : COCOA study
Coronavirus disease 2019 (COVID-19) pandemic has changed lifestyles dramatically. The impact of COVID-19 on inhalant sensitization remains unknown. The purpose of this study is to investigate whether the COVID-19 outbreak affects the changes of inhalant sensitization and allergic disease at age 7 according to a birth year in a general population-based birth cohort.
Source: Journal of Allergy and Clinical Immunology - February 1, 2023 Category: Allergy & Immunology Authors: Kun Baek Song, Min Jee Park, Eom Ji Choi, Eun Young Paek, Sungsu Jung, Jisun Yoon, Hyun-ju Cho, Bong Seong Kim, Kangmo Ahn, Kyung Won Kim, Youn Ho Shin, Dong In Suh, Soo-Jong Hong, So-Yeon Lee Source Type: research

Planning for Mpox on a College Campus: A Model-Based Decision-Support Tool
CONCLUSION: Based on our current understanding of mpox epidemiology among MSM in the United States, this model-based analysis suggests that future outbreaks of mpox on college campuses may be controlled with timely detection and isolation of symptomatic cases.PRIMARY FUNDING SOURCE: National Institutes of Health National Institute on Drug Abuse and National Institute of Allergy and Infectious Diseases.PMID:36716454 | DOI:10.7326/M22-2734
Source: Annals of Internal Medicine - January 30, 2023 Category: Internal Medicine Authors: Alexandra Savinkina Melanie Chitwood Jiye Kwon Virginia E Pitzer Gregg Gonsalves A David Paltiel Source Type: research