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Epidemiological trends of allergic diseases in adolescents
Conclusions: The prevalences of asthma, allergic rhinitis, and allergic rhinoconjunctivitis among adolescents in 2012 were found to be high, having increased in comparison with those found 10 years earlier, despite efforts in prevention, diagnosis, and treatment.RESUMO Objetivo: Avaliar as preval ências de asma, rinite alérgica e rinoconjuntivite alérgica em adolescentes da cidade de Belo Horizonte (MG) através do questionário do International Study of Asthma and Allergies in Childhood no ano de 2012, bem como compará-las com aquelas obtidas em estudos realizados 10 anos antes empregan do a mesma metodologia. Método...
Source: Jornal Brasileiro de Pneumologia - November 13, 2017 Category: Respiratory Medicine Source Type: research

Milonine, an Alkaloid of Cissampelos sympodialis Eichl. (Menispermaceae) Inhibits Histamine Release of Activated Mast Cells
AbstractMilonine is an alkaloid ofCissampelos sympodialis Eichl. (Menispermaceae), a plant used in the northeast of Brazil to treat allergies such as asthma, rhinitis, and other conditions. Previously, several alkaloids were isolated from its roots and leaves with pharmacological properties in asthma and acute inflammation models. Therefore, the aim of this study was to evaluate the milonine effect on mast cells degranulationin vivo andin vitro. Swiss mice (n = 8) were used in models of paw edema induced by carrageenan, compound 48/80, or histamine. One hour before challenge, the animals were treated with milonine (at di...
Source: Inflammation - August 15, 2017 Category: Allergy & Immunology Source Type: research

Association of Ugrp2 gene polymorphisms with adenoid hypertrophy in the pediatric population
Conclusion Some SNPs and their combinations in the Ugrp2 gene are associated with an increased risk of developing AH. Therefore, we tried to underline the importance of genetic factors associated with AH and AH-related clinical phenotypes.
Source: Brazilian Journal of Otorhinolaryngology - August 2, 2017 Category: ENT & OMF Source Type: research

Air pollution and its relationship to lung function among adolescents from Taubate, S ão Paulo, Brazil.
CONCLUSIONS: The amount of carbon present within the AMs of adolescents with asthma was not correlated with either lung function or residence location. Evaluations of the topography and local climatic conditions in Taubaté should be considered in future studies. PMID: 28757196 [PubMed - as supplied by publisher]
Source: Allergologia et Immunopathologia - July 27, 2017 Category: Allergy & Immunology Authors: Toledo MF, Saraiva-Romanholo BM, Oliveira RC, da Silva LF, Solé D Tags: Allergol Immunopathol (Madr) Source Type: research

Asthma in children and adolescents in Brazil: contribution of the International Study of Asthma and Allergies in Childhood (ISAAC)
Conclusions: In Brazil, the ISAAC study showed that asthma is a disease of high prevalence and impact in children and adolescents and should be seen as a Public Health problem. Important regional variations, not well understood yet, and several risk factors were found, which makes us wonder: is there only one or many asthmas in Brazil? Objetivo: Evaluar el asma en la población pediátrica brasileña por el protocolo del International Study of Asthma and Allergies in Childhood (ISAAC), internacionalmente estandarizado y validado. Fuentes de datos : El ISAAC, idealizado para maximizar el valor de estudios epidemiológicos...
Source: Revista Paulista de Pediatria - March 28, 2014 Category: Pediatrics Source Type: research

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