Reflections upon the article “Evaluation of the impact that the changes in tuberculosis treatment implemented in Brazil in 2009 have had on disease control in the country”
ABSTRACT Acute pulmonary thromboembolism (APTE) is a highly prevalent condition (104-183 cases per 100,000 person-years) and is potentially fatal. Approximately 20% of patients with APTE are hypotensive, being considered at high risk of death. In such patients, immediate lung reperfusion is necessary in order to reduce right ventricular afterload and to restore hemodynamic stability. To reduce pulmonary vascular resistance in APTE and, consequently, to improve right ventricular function, lung reperfusion strategies have been developed over time and widely studied in recent years. In this review, we focus on advances in the...
Source: Jornal Brasileiro de Pneumologia - July 19, 2018 Category: Respiratory Medicine Source Type: research

Hemoptysis in recurrent respiratory papillomatosis: also think about aspergillosis
ABSTRACT Acute pulmonary thromboembolism (APTE) is a highly prevalent condition (104-183 cases per 100,000 person-years) and is potentially fatal. Approximately 20% of patients with APTE are hypotensive, being considered at high risk of death. In such patients, immediate lung reperfusion is necessary in order to reduce right ventricular afterload and to restore hemodynamic stability. To reduce pulmonary vascular resistance in APTE and, consequently, to improve right ventricular function, lung reperfusion strategies have been developed over time and widely studied in recent years. In this review, we focus on advances in the...
Source: Jornal Brasileiro de Pneumologia - July 19, 2018 Category: Respiratory Medicine Source Type: research

Response to cytotoxic chemotherapy and overall survival in non-small cell lung cancer patients with positive or negative ERCC1 expression
ABSTRACT Acute pulmonary thromboembolism (APTE) is a highly prevalent condition (104-183 cases per 100,000 person-years) and is potentially fatal. Approximately 20% of patients with APTE are hypotensive, being considered at high risk of death. In such patients, immediate lung reperfusion is necessary in order to reduce right ventricular afterload and to restore hemodynamic stability. To reduce pulmonary vascular resistance in APTE and, consequently, to improve right ventricular function, lung reperfusion strategies have been developed over time and widely studied in recent years. In this review, we focus on advances in the...
Source: Jornal Brasileiro de Pneumologia - July 19, 2018 Category: Respiratory Medicine Source Type: research

Fat embolism syndrome: chest CT findings
ABSTRACT Acute pulmonary thromboembolism (APTE) is a highly prevalent condition (104-183 cases per 100,000 person-years) and is potentially fatal. Approximately 20% of patients with APTE are hypotensive, being considered at high risk of death. In such patients, immediate lung reperfusion is necessary in order to reduce right ventricular afterload and to restore hemodynamic stability. To reduce pulmonary vascular resistance in APTE and, consequently, to improve right ventricular function, lung reperfusion strategies have been developed over time and widely studied in recent years. In this review, we focus on advances in the...
Source: Jornal Brasileiro de Pneumologia - July 19, 2018 Category: Respiratory Medicine Source Type: research

Reperfusion in acute pulmonary thromboembolism
ABSTRACT Acute pulmonary thromboembolism (APTE) is a highly prevalent condition (104-183 cases per 100,000 person-years) and is potentially fatal. Approximately 20% of patients with APTE are hypotensive, being considered at high risk of death. In such patients, immediate lung reperfusion is necessary in order to reduce right ventricular afterload and to restore hemodynamic stability. To reduce pulmonary vascular resistance in APTE and, consequently, to improve right ventricular function, lung reperfusion strategies have been developed over time and widely studied in recent years. In this review, we focus on advances in the...
Source: Jornal Brasileiro de Pneumologia - July 19, 2018 Category: Respiratory Medicine Source Type: research

Characterization and outcomes of pulmonary alveolar proteinosis in Brazil: a case series
Conclusions: To our knowledge, this is the largest case series of patients with PAP ever conducted in Brazil. The survival rate was similar to that found at other center s. For symptomatic, hypoxemic patients, the treatment of choice is still WLL. Precautions should be taken in order to avoid complications, especially opportunistic infections.RESUMO Objetivo: A proteinose alveolar pulmonar (PAP) é uma doença rara, caracterizada pelo acúmulo alveolar de substância surfactante, composta por proteínas e lipídios. É causada por um déficit de atividade macrofágica, c...
Source: Jornal Brasileiro de Pneumologia - July 19, 2018 Category: Respiratory Medicine Source Type: research

Mini-thoracostomy with vacuum-assisted closure: a minimally invasive alternative to open-window thoracostomy
This study aims to analyze the safety and effectiveness of mini-thoracostomy with vacuum-assisted closure in an initial sample of patients.RESUMO A pleurostomia é uma opção frequente de tratamento para pacientes com empiema pleural fase III que não toleram decorticação pulmonar. Todavia, esse tratamento é considerado mutilante por envolver a confecção de um stoma torácico, que pode demorar anos para se fechar ou requerer nova cirurgia. Descreveu-s e recentemente uma técnica minimamente invasiva que associa uso intrapleural de curativo a vác...
Source: Jornal Brasileiro de Pneumologia - July 19, 2018 Category: Respiratory Medicine Source Type: research

Validity and reliability of assessing diaphragmatic mobility by area on X-rays of healthy subjects
ABSTRACT Objective: To investigate the concurrent validity, as well as the intra- and inter-rater reliability, of assessing diaphragmatic mobility by area (DMarea) on chest X-rays of healthy adults. Methods: We evaluated anthropometric parameters, pulmonary function, and diaphragmatic mobility in 43 participants. Two observers (rater A and rater B) determined diaphragmatic mobility at two time points. We used Pearson ’ s correlation coefficient to evaluate the correlation between DMarea and the assessment of diaphragmatic mobility by distance (DMdist). To evaluate intra- and inter-rater reliability, we used the intra...
Source: Jornal Brasileiro de Pneumologia - July 19, 2018 Category: Respiratory Medicine Source Type: research

Is the COPD Assessment Test sensitive for differentiating COPD patients from active smokers and nonsmokers without lung function impairment? A population-based study
ABSTRACT Objective: To assess COPD Assessment Test (CAT) scores in adults with and without COPD, as well as to compare the CAT scores for nonsmokers, former smokers, and smokers without COPD with those for patients with COPD. Methods: This was a cross-sectional population-based study (the Respira Floripa study). The study included adults ≥ 40 years of age residing in the city of Florian ópolis, Brazil. A total of 846 households were surveyed. In addition to completing the Respira Floripa questionnaire and the CAT, participants underwent pulmonary function testing. Results: We analyzed data on 1,057 participants (...
Source: Jornal Brasileiro de Pneumologia - July 19, 2018 Category: Respiratory Medicine Source Type: research

Obesity and asthma: clinical and laboratory characterization of a common combination
Conclusions: Obese individuals with asthma seem to present with poorer asthma control and lower pulmonary function values than do nonobese individuals. The proportion of subjects with nonatopic asthma was higher in the obese group. Our results suggest that obese individuals with asthma show a distinct inflammatory pattern and are more likely to present with difficult-to-control asthma than are nonobese individuals.RESUMO Objetivo: Avaliar a rela ção entre obesidade e asma. Métodos: Análise preliminar transversal de dados de um estudo de caso-controle com 925 pacientes com asma leve a moderada ou...
Source: Jornal Brasileiro de Pneumologia - July 19, 2018 Category: Respiratory Medicine Source Type: research

The triad of obstructive sleep apnea syndrome, COPD, and obesity: sensitivity of sleep scales and respiratory questionnaires
Conclusions: The confounding factors present in the triad of OSAS, COPD, and obesity prevented the perception of increased daytime sleepiness and high risk for OSAS. We observed no worsening of dyspnea perception or quality of life.RESUMO Objetivo: Avaliar se a presen ça de síndrome da apneia obstrutiva do sono (SAOS) modifica a percepção de queixas respiratórias e de qualidade de vida em pacientes com DPOC por meio de questionários específicos, além de verificar se escalas de sonolência diurna e de rastreamento para SAOS podem ser empregadas na tríade SA...
Source: Jornal Brasileiro de Pneumologia - July 19, 2018 Category: Respiratory Medicine Source Type: research

Comparison of two smoking cessation interventions for inpatients
This study aimed to compare the effectiveness of two cognitive behavioral therapy-based smoking cessation interventions initiated during hospitalization and to evaluate the factors related to relapse after discharge. Methods: This was a prospective randomized study involving 90 smokers hospitalized in a university hospital. We collected data related to sociodemographic characteristics, reasons for admission, smoking-related diseases, smoking history, the degree of nicotine dependence (ND), and the level of craving. Patients were divided into two treatment groups: brief intervention (BrInter, n = 45); and intensive interven...
Source: Jornal Brasileiro de Pneumologia - July 19, 2018 Category: Respiratory Medicine Source Type: research

Reference values for the six-minute pegboard and ring test in healthy adults in Brazil
ABSTRACT Objective: To determine reference values for the six-minute pegboard and ring test (6PBRT) in healthy adults in Brazil, correlating the results with arm length, circumference of the upper arm/forearm of the dominant arm, and the level of physical activity. Methods: The participants (all volunteers) performed two 6PBRTs, 30 min apart. They were instructed to move as many rings as possible in six minutes. The best test result was selected for data analysis. Results: The sample comprised 104 individuals, all over 30 years of age. Reference values were reported by age bracket. We found that age correlated with 6PBRT r...
Source: Jornal Brasileiro de Pneumologia - July 19, 2018 Category: Respiratory Medicine Source Type: research

Relationship between availability of physiotherapy services and ICU costs
Conclusions: In the population studied, total costs and staff costs were lower in the PT-24 group than in the PT-12 group. The h/day availability of physiotherapy services was found to be a significant predictor of ICU costs.RESUMO Objetivo: Determinar se a disponibilidade de servi ços de fisioterapia 24 h/dia reduz os custos de UTI comparada à disponibilidade padrão de 12 h/dia entre pacientes admitidos pela primeira vez na UTI. Métodos: Estudo de prevalência observacional, envolvendo 815 pacientes ≥ 18 anos de idade que estavam em ventila ção mecânica invasiva (VMI...
Source: Jornal Brasileiro de Pneumologia - July 19, 2018 Category: Respiratory Medicine Source Type: research

Internal and external validity: can you apply research study results to your patients?
(Source: Jornal Brasileiro de Pneumologia)
Source: Jornal Brasileiro de Pneumologia - July 19, 2018 Category: Respiratory Medicine Source Type: research

Unilateral hyperlucent lung
(Source: Jornal Brasileiro de Pneumologia)
Source: Jornal Brasileiro de Pneumologia - July 19, 2018 Category: Respiratory Medicine Source Type: research

Vascular reperfusion in pulmonary thromboembolism: certainties and uncertainties
(Source: Jornal Brasileiro de Pneumologia)
Source: Jornal Brasileiro de Pneumologia - July 19, 2018 Category: Respiratory Medicine Source Type: research

Opening windows of opportunity for smoking cessation treatment
(Source: Jornal Brasileiro de Pneumologia)
Source: Jornal Brasileiro de Pneumologia - July 19, 2018 Category: Respiratory Medicine Source Type: research

Reference values for assessing the arms: are we seeing a light at the end of the tunnel?
(Source: Jornal Brasileiro de Pneumologia)
Source: Jornal Brasileiro de Pneumologia - July 19, 2018 Category: Respiratory Medicine Source Type: research

Cost analysis in the ICU from the standpoint of physical therapy
(Source: Jornal Brasileiro de Pneumologia)
Source: Jornal Brasileiro de Pneumologia - July 19, 2018 Category: Respiratory Medicine Source Type: research

The importance of the World Symposium on Pulmonary Hypertension
(Source: Jornal Brasileiro de Pneumologia)
Source: Jornal Brasileiro de Pneumologia - July 19, 2018 Category: Respiratory Medicine Source Type: research

Rapidly growing pulmonary ground-glass nodule caused by metastatic melanoma lacking uptake on 18F-FDG PET-CT
The objective of this systematic review was to select articles including chest X-ray or chest CT findings in patients who developed pulmonary tuberculosis following solid organ transplantation (lung, kidney, or liver). The following search terms were used: “ tuberculosis ” ; “ transplants ” ; “ transplantation ” ; “ mycobacterium ” ; and “ lung ” . The databases used in this review were PubMed and the Brazilian Biblioteca Virtual em Sa úde (Virtual Health Library). We selected articles in English, Portuguese, or Spanish, regardless of the year of publicatio...
Source: Jornal Brasileiro de Pneumologia - May 21, 2018 Category: Respiratory Medicine Source Type: research

Knowledge and perceptions of tuberculosis transmission and prevention among physicians and nurses in three Brazilian capitals with high incidence of tuberculosis
The objective of this systematic review was to select articles including chest X-ray or chest CT findings in patients who developed pulmonary tuberculosis following solid organ transplantation (lung, kidney, or liver). The following search terms were used: “ tuberculosis ” ; “ transplants ” ; “ transplantation ” ; “ mycobacterium ” ; and “ lung ” . The databases used in this review were PubMed and the Brazilian Biblioteca Virtual em Sa úde (Virtual Health Library). We selected articles in English, Portuguese, or Spanish, regardless of the year of publicatio...
Source: Jornal Brasileiro de Pneumologia - May 21, 2018 Category: Respiratory Medicine Source Type: research

Giant pulmonary artery aneurysm in a patient with schistosomiasis-associated pulmonary arterial hypertension
The objective of this systematic review was to select articles including chest X-ray or chest CT findings in patients who developed pulmonary tuberculosis following solid organ transplantation (lung, kidney, or liver). The following search terms were used: “ tuberculosis ” ; “ transplants ” ; “ transplantation ” ; “ mycobacterium ” ; and “ lung ” . The databases used in this review were PubMed and the Brazilian Biblioteca Virtual em Sa úde (Virtual Health Library). We selected articles in English, Portuguese, or Spanish, regardless of the year of publicatio...
Source: Jornal Brasileiro de Pneumologia - May 21, 2018 Category: Respiratory Medicine Source Type: research

Chest X-ray and chest CT findings in patients diagnosed with pulmonary tuberculosis following solid organ transplantation: a systematic review
The objective of this systematic review was to select articles including chest X-ray or chest CT findings in patients who developed pulmonary tuberculosis following solid organ transplantation (lung, kidney, or liver). The following search terms were used: “ tuberculosis ” ; “ transplants ” ; “ transplantation ” ; “ mycobacterium ” ; and “ lung ” . The databases used in this review were PubMed and the Brazilian Biblioteca Virtual em Sa úde (Virtual Health Library). We selected articles in English, Portuguese, or Spanish, regardless of the year of publicatio...
Source: Jornal Brasileiro de Pneumologia - May 21, 2018 Category: Respiratory Medicine Source Type: research

New and repurposed drugs to treat multidrug- and extensively drug-resistant tuberculosis
The objective of this review was to summarize what has been achieved to date, as far as new and repurposed drugs are concerned, with a special focus on delamanid, bedaquiline, pretomanid, clofazimine, carbapenems, and linezolid. After more than 40 years of neglect, greater attention has recently been paid to the need for new drugs to fight the “ white plague ” , and promising results are being reported.RESUMO A tuberculose multirresistente (TB-MDR, do ingl ês multidrug-resistant) e a extensivamente resistente (TB-XDR, do inglês extensively drug-resistant) continuam representando um desafio para os c...
Source: Jornal Brasileiro de Pneumologia - May 21, 2018 Category: Respiratory Medicine Source Type: research

Risk factors for tuberculosis: diabetes, smoking, alcohol use, and the use of other drugs
ABSTRACT Tuberculosis continues to be a major public health problem. Although efforts to control the epidemic have reduced mortality and incidence, there are several predisposing factors that should be modified in order to reduce the burden of the disease. This review article will address some of the risk factors associated with tuberculosis infection and active tuberculosis, including diabetes, smoking, alcohol use, and the use of other drugs, all of which can also contribute to poor tuberculosis treatment results. Tuberculosis can also lead to complications in the course and management of other diseases, such as diabetes...
Source: Jornal Brasileiro de Pneumologia - May 21, 2018 Category: Respiratory Medicine Source Type: research

Epidemiological aspects, clinical manifestations, and prevention of pediatric tuberculosis from the perspective of the End TB Strategy
ABSTRACT Tuberculosis continues to be a public health priority in many countries. In 2015, tuberculosis killed 1.4 million people, including 210,000 children. Despite the recent progress made in the control of tuberculosis in Brazil, it is still one of the countries with the highest tuberculosis burdens. In 2015, there were 69,000 reported cases of tuberculosis in Brazil and tuberculosis was the cause of 4,500 deaths in the country. In 2014, the World Health Organization approved the End TB Strategy, which set a target date of 2035 for meeting its goals of reducing the tuberculosis incidence by 90% and reducing the number ...
Source: Jornal Brasileiro de Pneumologia - May 21, 2018 Category: Respiratory Medicine Source Type: research

Who are the patients with tuberculosis who are diagnosed in emergency facilities? An analysis of treatment outcomes in the state of São Paulo, Brazil
Conclusions: In the state of São Paulo, one in every four tuberculosis patients is diagnosed in EFs, a diagnosis of tuberculosis in EFs being associated with poor treatment outcomes. At the municipal level, an EF diagnosis of tuberculosis is associated with structural and socioeconomic indicators, indicating areas for improvement.RESUMO Objetivo: O diagn óstico e tratamento precoce da tuberculose são determinantes de melhores desfechos e controle eficaz da doença. Embora a tuberculose deva ser diagnosticada e tratada idealmente na atenção primária à saúde, uma ...
Source: Jornal Brasileiro de Pneumologia - May 21, 2018 Category: Respiratory Medicine Source Type: research

Predictors of mortality among intensive care unit patients coinfected with tuberculosis and HIV
ABSTRACT Objective: To identify factors predictive of mortality in patients admitted to the ICU with tuberculosis (TB)/HIV coinfection in the Manaus, Amazon Region. Methods: This was a retrospective cohort study of TB/HIV coinfected patients over 18 years of age who were admitted to an ICU in the city of Manaus, Brazil, between January of 2011 and December of 2014. Sociodemographic, clinical, and laboratory variables were assessed. To identify factors predictive of mortality, we employed a Cox proportional hazards model. Results: During the study period, 120 patients with TB/HIV coinfection were admitted to the ICU. The me...
Source: Jornal Brasileiro de Pneumologia - May 21, 2018 Category: Respiratory Medicine Source Type: research

Rapid molecular test for tuberculosis: impact of its routine use at a referral hospital
Conclusions: The use of the Xpert MTB/RIF test, under routine conditions, significantly increased the detection of cases of tuberculosis among sputum smear-negative patients.RESUMO Objetivo: Avaliar o impacto do teste r ápido molecular automatizado Xpert MTB/RIF, utilizado para a detecção de Mycobacterium tuberculosis e sua resistência à rifampicina, em condições de rotina, em um hospital de referência no estado da Bahia. Métodos: Estudo descritivo retrospectivo utilizando o banco de dados do Laboratório de Micobacteriologia do Hospital Especializado Oct&a...
Source: Jornal Brasileiro de Pneumologia - May 21, 2018 Category: Respiratory Medicine Source Type: research

Nontuberculous mycobacterial lung disease in a high tuberculosis incidence setting in Brazil
Conclusions: MAC and M. kansasii were the most prevalent species involved in NTMLD in the state, similarly to what occurs in other regions of Brazil. Data on regional epidemiology of NTMLD, its specific etiology, and associated conditions are essential to establish appropriate treatment, since each species requires specific regimens. Most patients with NTMLD had received previous tuberculosis treatment, which might lead to development of resistance and late diagnosis.RESUMO Objetivo: A incid ência de doença pulmonar causada por micobactérias não tuberculosas (MNT) tem aumentado em todo o mundo. N...
Source: Jornal Brasileiro de Pneumologia - May 21, 2018 Category: Respiratory Medicine Source Type: research

Impact of smoking on sputum culture conversion and pulmonary tuberculosis treatment outcomes in Brazil: a retrospective cohort study
Conclusions: In our sample, the probability of a delay in sputum culture conversion was higher in current smokers than in never-smokers, as was the probability of a poor treatment outcome.RESUMO Objetivo: Avaliar o impacto do tabagismo no desfecho do tratamento da tuberculose pulmonar (TBP) e na taxa de convers ão da cultura de Mycobacterium tuberculosis no escarro ao final do segundo mês de tratamento em pacientes com TBP confirmada por cultura em um local com incidência de tuberculose moderada no Brasil. Métodos: Estudo de coorte retrospectivo envolvendo pacientes com TBP diagnosticados e tratad...
Source: Jornal Brasileiro de Pneumologia - May 21, 2018 Category: Respiratory Medicine Source Type: research

Clinical aspects in patients with pulmonary infection caused by mycobacteria of the Mycobacterium abscessus complex, in the Brazilian Amazon
ABSTRACT Objective: To describe the clinical manifestations of patients with pulmonary infection caused by mycobacteria of the Mycobacterium abscessus complex (MABSC), and to compare these manifestations with those of patients infected with other nontuberculous mycobacteria (NTM). Methods: This was a retrospective cohort study involving 43 patients divided into two groups: the MABSC group, consisting of patients with pulmonary infection caused by MABSC (n = 17); and the NTM group, consisting of patients with pulmonary infection caused by NTM other than MABSC (n = 26). Patients were previously treated with a regimen of rifa...
Source: Jornal Brasileiro de Pneumologia - May 21, 2018 Category: Respiratory Medicine Source Type: research

Sequential analysis as a tool for detection of amikacin ototoxicity in the treatment of multidrug-resistant tuberculosis
Conclusions: The statistical method used in this study makes it possible to conclude that, over the six-month period, amikacin-associated hearing threshold shifts were detected by HFA and PTA, and that DPOAE testing was not efficient in detecting such shifts.RESUMO Objetivo: Verificar a detec ção precoce de ototoxicidade causada pelo uso de amicacina numa população tratada para tuberculose multirresistente (TBMR) por meio da realização de três testes distintos: audiometria tonal liminar (ATL), audiometria de altas frequências (AAF) e pesquisa de emissões otoac&ua...
Source: Jornal Brasileiro de Pneumologia - May 21, 2018 Category: Respiratory Medicine Source Type: research

Inclusion and exclusion criteria in research studies: definitions and why they matter
(Source: Jornal Brasileiro de Pneumologia)
Source: Jornal Brasileiro de Pneumologia - May 21, 2018 Category: Respiratory Medicine Source Type: research

Lymph node calcifications
(Source: Jornal Brasileiro de Pneumologia)
Source: Jornal Brasileiro de Pneumologia - May 21, 2018 Category: Respiratory Medicine Source Type: research

Tuberculosis: where are we?
(Source: Jornal Brasileiro de Pneumologia)
Source: Jornal Brasileiro de Pneumologia - May 21, 2018 Category: Respiratory Medicine Source Type: research

The role of the Brazilian Tuberculosis Research Network in national and international efforts to eliminate tuberculosis
(Source: Jornal Brasileiro de Pneumologia)
Source: Jornal Brasileiro de Pneumologia - May 21, 2018 Category: Respiratory Medicine Source Type: research

Eliminating tuberculosis in Latin America: making it the point
(Source: Jornal Brasileiro de Pneumologia)
Source: Jornal Brasileiro de Pneumologia - May 21, 2018 Category: Respiratory Medicine Source Type: research

Tuberculosis series
(Source: Jornal Brasileiro de Pneumologia)
Source: Jornal Brasileiro de Pneumologia - May 21, 2018 Category: Respiratory Medicine Source Type: research

Extracorporeal membrane oxygenation in an awake patient as a bridge to lung transplantation
The objective of the present study was to determine the sleep characteristics of a patient undergoing polysomnography (PSG) in three Colombian cities at different altitudes (Bogot á, at 2,640 m above sea level [ASL]; Bucaramanga, at 959 m ASL; and Santa Marta, at 15 m ASL). The patient was an obese man with diabetes and suspected OSA. All PSG recordings were scored and interpreted in accordance with American Academy of Sleep Medicine criteria. In Bogotá, PSG revealed modera te OSA (an apnea-hypopnea index [AHI] of 21 events/h); in Bucaramanga, PSG revealed increased upper airway resistance (an AHI of 2 events...
Source: Jornal Brasileiro de Pneumologia - March 12, 2018 Category: Respiratory Medicine Source Type: research

Sleep characteristics in an adult with sleep complaints in three cities at different altitudes
The objective of the present study was to determine the sleep characteristics of a patient undergoing polysomnography (PSG) in three Colombian cities at different altitudes (Bogot á, at 2,640 m above sea level [ASL]; Bucaramanga, at 959 m ASL; and Santa Marta, at 15 m ASL). The patient was an obese man with diabetes and suspected OSA. All PSG recordings were scored and interpreted in accordance with American Academy of Sleep Medicine criteria. In Bogotá, PSG revealed modera te OSA (an apnea-hypopnea index [AHI] of 21 events/h); in Bucaramanga, PSG revealed increased upper airway resistance (an AHI of 2 events...
Source: Jornal Brasileiro de Pneumologia - March 12, 2018 Category: Respiratory Medicine Source Type: research

Lung cancer in Brazil
ABSTRACT Lung cancer is one of the most incident types of cancer and a leading cause of cancer mortality in Brazil. We reviewed the current status of lung cancer by searching relevant data on prevention, diagnosis, and treatment in the country. This review highlights several issues that need to be addressed, including smoking control, patient lack of awareness, late diagnosis, and disparities in the access to cancer health care facilities in Brazil. We propose strategies to help overcome these limitations and challenge health care providers, as well as the society and governmental representatives, to work together and to t...
Source: Jornal Brasileiro de Pneumologia - March 12, 2018 Category: Respiratory Medicine Source Type: research

Between-occasion repeatability of fractional exhaled nitric oxide measurements in children
ABSTRACT The aim of the study was to assess short-term repeatability of measurements of fractional exhaled nitric oxide (FENO) and its correlates in children in the 6- to 9-year age bracket participating in a respiratory epidemiological survey. FENO was measured in two sessions one week apart in 101 children. Participants were divided into three groups: asymptomatic (n = 76); symptomatic (n = 14); and asthma (n = 11). Absolute and relative differences between the measurements, as well as concordance correlation coefficients, were used in order to assess repeatability. The two FENO measurements were strongly correlated (0.9...
Source: Jornal Brasileiro de Pneumologia - March 12, 2018 Category: Respiratory Medicine Source Type: research

Association between the display of cigarette packs at the point of sale and smoking susceptibility among adolescents in Brazil
ABSTRACT This was a cross-sectional study aimed at determining the association between exposure to tobacco displays at the point of sale and susceptibility to smoking in schoolchildren in the 14- to 17-year age bracket. Of the participating students, 69.0%, 21.3%, and 9.7% were classified as never smokers, experimenters, and smokers, respectively. Of the participants who were classified as being exposed to smoking, 18.9% were susceptible to smoking. Of the participants who were classified as being unexposed to smoking, 12.9% were susceptible to smoking (OR = 1.56; 95% CI: 1.04 -2.35; p = 0.029). Exposure to point-of-sale t...
Source: Jornal Brasileiro de Pneumologia - March 12, 2018 Category: Respiratory Medicine Source Type: research

Evaluation of smoking cessation treatment initiated during hospitalization in patients with heart disease or respiratory disease
ABSTRACT Objective: To evaluate the effectiveness of a smoking cessation program, delivered by trained health care professionals, in patients hospitalized for acute respiratory disease (RD) or heart disease (HD). Methods: Of a total of 393 patients evaluated, we included 227 (146 and 81 active smokers hospitalized for HD and RD, respectively). All participants received smoking cessation treatment during hospitalization and were followed in a cognitive-behavioral smoking cessation program for six months after hospital discharge. Results: There were significant differences between the HD group and the RD group regarding part...
Source: Jornal Brasileiro de Pneumologia - March 12, 2018 Category: Respiratory Medicine Source Type: research

Soluble urokinase-type plasminogen activator receptor as a measure of treatment response in acute exacerbation of COPD
Conclusions: Monitoring the serum suPAR level can be helpful in the evaluation of the COPD treatment response and might be a valuable biomarker for determining the prognosis of AECOPD. Because serum suPAR correlated with plasma fibrinogen, both markers could be predictive of AECOPD.RESUMO Objetivo: Avaliar o valor do soluble urokinase-type plasminogen activator receptor (suPAR, receptor do ativador de plasminog ênio tipo uroquinase solúvel) no diagnóstico de exacerbação aguda da DPOC (EADPOC) e no monitoramento da resposta ao tratamento, analisando-se a relação entre o suPAR ...
Source: Jornal Brasileiro de Pneumologia - March 12, 2018 Category: Respiratory Medicine Source Type: research

Is suicidal ideation associated with allergic asthma and allergic rhinitis?
ABSTRACT Objective: To investigate whether there is an association between suicidal ideation (SI) and allergic diseases in adults. Methods: This was a comparative cross-sectional study involving individuals ranging from 20 to 50 years of age recruited from a university hospital in the city of Guadalajara, Mexico. We included patients with a confirmed diagnosis of allergic asthma, those with a confirmed diagnosis of allergic rhinitis, and healthy controls. All subjects completed the Beck Depression Inventory-II (BDI-II), which includes an item that evaluates the presence of suicidal thoughts or desires within the last two w...
Source: Jornal Brasileiro de Pneumologia - March 12, 2018 Category: Respiratory Medicine Source Type: research

Complexity of autonomic nervous system function in individuals with COPD
Conclusions: Individuals with COPD show a reduction in both sympathetic and parasympathetic activity, associated with decreased complexity of autonomic nervous system function, as identified by RPs, which provide important complementary information in the detection of autonomic changes in this population.RESUMO Objetivo: Avaliar a modula ção autonômica de indivíduos com DPOC, comparados com um grupo controle saudável, por meio do plot de recorrência (PR) associado a métodos lineares da variabilidade da frequência cardíaca (VFC). Métodos: Foram avaliados dad...
Source: Jornal Brasileiro de Pneumologia - March 12, 2018 Category: Respiratory Medicine Source Type: research