Cross-cultural adaptation of the Cambridge Pulmonary Hypertension Outcome Review for use in patients with pulmonary hypertension in Colombia
Conclusions: The Spanish-language version of the CAMPHOR developed for use in Colombia was the result of a translation and cultural adaptation process that allows us to consider it equivalent to the original version, having shown good psychometric properties in the study sample. Therefore, its use to assess the impact of interventions on the HRQoL of patients with PAH or CTEPH is recommended, in research and clinical practice.RESUMEN Objetivo: Realizar la adaptaci ón transcultural del cuestionario Cambridge Pulmonary Hypertension Outcome Review (CAMPHOR) como instrumento para evaluar la percepción de sí...
Source: Jornal Brasileiro de Pneumologia - July 29, 2019 Category: Respiratory Medicine Source Type: research

Multidisciplinary education with a focus on COPD in primary health care
ABSTRACT Objective: To evaluate the use of video lessons on the topic of COPD as a training tool for a multidisciplinary team working in the primary health care sector. Methods: This was a quasi-experimental study involving a multidisciplinary team working at a primary health care clinic. The level of knowledge about COPD was measured by applying a specific, 16-item questionnaire - before, immediately after, and three months after the video lessons. In a set of six structured video lessons, the training focused on the prevention, case-finding, treatment, and monitoring of cases of COPD. The data were analyzed with the Frie...
Source: Jornal Brasileiro de Pneumologia - July 29, 2019 Category: Respiratory Medicine Source Type: research

Anthropometric status of individuals with COPD in the city of São Paulo, Brazil, over time - analysis of a population-based study
Conclusions: Between the two phases of the study, the subjects with mild COPD showed increases in weight and BMI, whereas those with a more severe form of the disease showed reductions.RESUMO Objetivo: Avaliar a evolu ção dos dados antropométricos obtidos em uma pesquisa latino-americana realizada em duas fases (basal, em 2003, e seguimento, em 2012) na cidade de São Paulo. Métodos: Estudo de base populacional que avaliou indivíduos com idade ≥ 40 anos com o objetivo de definir a preval ência da DPOC e sua relação com alguns fatores de risco. A avaliaç...
Source: Jornal Brasileiro de Pneumologia - July 29, 2019 Category: Respiratory Medicine Source Type: research

Familial pulmonary fibrosis: a heterogeneous spectrum of presentations
Conclusions: Patients with FPF can present with a wide variety of clinical features. Most HRCT scans of these patients exhibit patterns not typical of usual interstitial pneumonia. The family history of fibrotic lung diseases should be investigated in all patients under suspicion, regardless of their age.RESUMO Objetivo: Descrever as caracter ísticas clínicas, funcionais e radiológicas de um grupo de casos índice diagnosticados com fibrose pulmonar familiar (FPF) no Brasil. Métodos: Trinta e cinco pacientes com FPF (18 mulheres; 51,4%), com mediana de idade de 66,0 anos (variaç&ati...
Source: Jornal Brasileiro de Pneumologia - June 10, 2019 Category: Respiratory Medicine Source Type: research

Effects of the implementation of a hand hygiene education program among ICU professionals: an interrupted time-series analysis
ABSTRACT Objective: To evaluate the effects that a hand hygiene education program has on the compliance of health professionals in an ICU. Methods: This was a quasi-experimental study with an interrupted time-series design, conducted over a 12-month period: the 5 months preceding the implementation of a hand hygiene education program (baseline period); the 2 months of the intensive (intervention) phase of the program; and the first 5 months thereafter (post-intervention phase). Hand hygiene compliance was monitored by one of the researchers, unbeknownst to the ICU team. The primary outcome measure was the variation in the ...
Source: Jornal Brasileiro de Pneumologia - June 10, 2019 Category: Respiratory Medicine Source Type: research

Inflammatory lung injury in rabbits: effects of high-frequency oscillatory ventilation in the prone position
ABSTRACT Objective: To compare the effects that prone and supine positioning during high-frequency oscillatory ventilation (HFOV) have on oxygenation and lung inflammation, histological injury, and oxidative stress in a rabbit model of acute lung injury (ALI). Methods: Thirty male Norfolk white rabbits were induced to ALI by tracheal saline lavage (30 mL/kg, 38 °C). The injury was induced during conventional mechanical ventilation, and ALI was considered confirmed when a PaO2/FiO2 ratio
Source: Jornal Brasileiro de Pneumologia - March 25, 2019 Category: Respiratory Medicine Source Type: research

Effects of manual chest compression on expiratory flow bias during the positive end-expiratory pressure-zero end-expiratory pressure maneuver in patients on mechanical ventilation
Conclusions: The PEEP-ZEEP maneuver, without MCC, resulted in an expiratory flow bias superior to that neces sary to facilitate pulmonary secretion removal. Combining MCC with the PEEP-ZEEP maneuver increased the expiratory flow bias, which increases the potential of the maneuver to remove secretions.RESUMO Objetivo: Avaliar os efeitos da compress ão torácica manual (CTM) sobre o flow bias expiratório durante a manobra positive end-expiratory pressure-zero end-expiratory pressure (PEEP-ZEEP) para a remoção de secreção em pacientes sob ventilação mecânica ...
Source: Jornal Brasileiro de Pneumologia - March 12, 2019 Category: Respiratory Medicine Source Type: research

Probe-based confocal laser endomicroscopy of the airways: physiological and pathological characteristics of preneoplastic and neoplastic lesions
ABSTRACT Dysfunctional breathing (DB) is a respiratory condition characterized by irregular breathing patterns that occur either in the absence of concurrent diseases or secondary to cardiopulmonary diseases. Although the primary symptom is often dyspnea or “ air hunger ” , DB is also associated with nonrespiratory symptoms such as dizziness and palpitations. DB has been identified across all ages. Its prevalence among adults in primary care in the United Kingdom is approximately 9.5%. In addition, among individuals with asthma, a positive diagnosis of DB is found in a third of women and a fifth of men. Althoug...
Source: Jornal Brasileiro de Pneumologia - March 1, 2019 Category: Respiratory Medicine Source Type: research

Evaluation of the gauge of needles used in the collection of specimens during endobronchial ultrasound-guided transbronchial needle aspiration
ABSTRACT Dysfunctional breathing (DB) is a respiratory condition characterized by irregular breathing patterns that occur either in the absence of concurrent diseases or secondary to cardiopulmonary diseases. Although the primary symptom is often dyspnea or “ air hunger ” , DB is also associated with nonrespiratory symptoms such as dizziness and palpitations. DB has been identified across all ages. Its prevalence among adults in primary care in the United Kingdom is approximately 9.5%. In addition, among individuals with asthma, a positive diagnosis of DB is found in a third of women and a fifth of men. Althoug...
Source: Jornal Brasileiro de Pneumologia - March 1, 2019 Category: Respiratory Medicine Source Type: research

Solitary fibrous tumor of the pleura: a rare cause of elevation of the right lung base
ABSTRACT Dysfunctional breathing (DB) is a respiratory condition characterized by irregular breathing patterns that occur either in the absence of concurrent diseases or secondary to cardiopulmonary diseases. Although the primary symptom is often dyspnea or “ air hunger ” , DB is also associated with nonrespiratory symptoms such as dizziness and palpitations. DB has been identified across all ages. Its prevalence among adults in primary care in the United Kingdom is approximately 9.5%. In addition, among individuals with asthma, a positive diagnosis of DB is found in a third of women and a fifth of men. Althoug...
Source: Jornal Brasileiro de Pneumologia - March 1, 2019 Category: Respiratory Medicine Source Type: research

Evaluation of bone disease in patients with cystic fibrosis and end-stage lung disease
ABSTRACT Objective: Bone disease is a common comorbidity in patients with cystic fibrosis (CF). We sought to determine risk factors and identify potential biochemical markers for CF-related bone disease (CFBD) in a unique cohort of CF patients with end-stage lung disease undergoing lung transplantation (LTx) evaluation. Methods: All of the CF patients who were evaluated for LTx at our center between November of 1992 and December of 2010 were included in the study. Clinical data and biochemical markers of bone turnover, as well as bone mineral density (BMD) at the lumbar spine and femoral neck, were evaluated. Spearman &rsq...
Source: Jornal Brasileiro de Pneumologia - March 1, 2019 Category: Respiratory Medicine Source Type: research

Writing an effective response to reviewers: the goal is to improve the study and get it published!
(Source: Jornal Brasileiro de Pneumologia)
Source: Jornal Brasileiro de Pneumologia - March 1, 2019 Category: Respiratory Medicine Source Type: research

Should we use prognostic scores for acute pulmonary thromboembolism in clinical practice?
(Source: Jornal Brasileiro de Pneumologia)
Source: Jornal Brasileiro de Pneumologia - March 1, 2019 Category: Respiratory Medicine Source Type: research

Pleural effusion caused by infection with Listeria monocytogenes: etiopathogenesis and treatment
ABSTRACT Dysfunctional breathing (DB) is a respiratory condition characterized by irregular breathing patterns that occur either in the absence of concurrent diseases or secondary to cardiopulmonary diseases. Although the primary symptom is often dyspnea or “ air hunger ” , DB is also associated with nonrespiratory symptoms such as dizziness and palpitations. DB has been identified across all ages. Its prevalence among adults in primary care in the United Kingdom is approximately 9.5%. In addition, among individuals with asthma, a positive diagnosis of DB is found in a third of women and a fifth of men. Althoug...
Source: Jornal Brasileiro de Pneumologia - February 25, 2019 Category: Respiratory Medicine Source Type: research

Does everyone who quit smoking gain weight? A real-world prospective cohort study
Conclusions: Weight gain is not necessarily associated with smoking cessation, and smokers who are motivated to quit should be informed of that fact. This information could also be useful for addressing smokers who are still undecided because of possibility of weight gain.RESUMO Objetivo: Avaliar as altera ções de peso após 12 meses de abstinência do tabagismo confirmada bioquimicamente, comparando pacientes que perderam peso ou mantiveram o peso basal com os que ganharam peso. Métodos: Estudo prospectivo de coorte do mundo real realizado no Ambulatório de Cessação do ...
Source: Jornal Brasileiro de Pneumologia - February 25, 2019 Category: Respiratory Medicine Source Type: research

Incidence and morphological characteristics of the reversed halo sign in patients with acute pulmonary embolism and pulmonary infarction undergoing computed tomography angiography of the pulmonary arteries
Conclusions: A diagnosis of PE should be considered when there are findings such as those described here, even in patients with nonspecific clinical symptoms.RESUMO Objetivo: Verificar a incid ência do sinal do halo invertido (SHI) associado a infartos pulmonares (IP) relacionados ao tromboembolismo pulmonar (TEP) agudo, identificado por angiotomografia (angio-TC) de artérias pulmonares, e demonstrar as principais características morfológicas do SHI. Métodos: Foram avaliadas 993 ang io-TCs, após estratificação de risco clínico para TEP entre janeiro de 2010 e de...
Source: Jornal Brasileiro de Pneumologia - February 25, 2019 Category: Respiratory Medicine Source Type: research

Validation of the Pulmonary Embolism Severity Index for risk stratification after acute pulmonary embolism in a cohort of patients in Brazil
Conclusions: The PESI adequately predicted the prognosis after acute PE in this sample of the population of Brazil. The cluster analysis based on the original version is the most appropriate analysis in this setting.RESUMO Objetivo: Pulmonary Embolism Severity Index (PESI) foi desenvolvido para a estratifica ção de risco após tromboembolia pulmonar (TEP) aguda. Nosso objetivo foi validá-lo para uso no Brasil. Métodos: Estudo retrospectivo unicêntrico incluindo pacientes com TEP admitidos numa unidade de emergência. O PESI (versão original e simplificada) foi calculado u...
Source: Jornal Brasileiro de Pneumologia - February 25, 2019 Category: Respiratory Medicine Source Type: research

Hyperinflation surrounding a solitary nodule
(Source: Jornal Brasileiro de Pneumologia)
Source: Jornal Brasileiro de Pneumologia - February 25, 2019 Category: Respiratory Medicine Source Type: research

COPD: more treatment will translate to better breathing. Will it?
(Source: Jornal Brasileiro de Pneumologia)
Source: Jornal Brasileiro de Pneumologia - February 25, 2019 Category: Respiratory Medicine Source Type: research

Jornal Brasileiro de Pneumologia and Sociedade Brasileira de Pneumologia e Tisiologia: perspectives for the next four years
(Source: Jornal Brasileiro de Pneumologia)
Source: Jornal Brasileiro de Pneumologia - February 18, 2019 Category: Respiratory Medicine Source Type: research

Use of thrombolytic agents in the treatment of acute pulmonary thromboembolism: things are not as simple as you might think
ABSTRACT Dysfunctional breathing (DB) is a respiratory condition characterized by irregular breathing patterns that occur either in the absence of concurrent diseases or secondary to cardiopulmonary diseases. Although the primary symptom is often dyspnea or “ air hunger ” , DB is also associated with nonrespiratory symptoms such as dizziness and palpitations. DB has been identified across all ages. Its prevalence among adults in primary care in the United Kingdom is approximately 9.5%. In addition, among individuals with asthma, a positive diagnosis of DB is found in a third of women and a fifth of men. Althoug...
Source: Jornal Brasileiro de Pneumologia - February 11, 2019 Category: Respiratory Medicine Source Type: research

Dysfunctional breathing: what do we know?
ABSTRACT Dysfunctional breathing (DB) is a respiratory condition characterized by irregular breathing patterns that occur either in the absence of concurrent diseases or secondary to cardiopulmonary diseases. Although the primary symptom is often dyspnea or “ air hunger ” , DB is also associated with nonrespiratory symptoms such as dizziness and palpitations. DB has been identified across all ages. Its prevalence among adults in primary care in the United Kingdom is approximately 9.5%. In addition, among individuals with asthma, a positive diagnosis of DB is found in a third of women and a fifth of men. Althoug...
Source: Jornal Brasileiro de Pneumologia - February 11, 2019 Category: Respiratory Medicine Source Type: research

Is a low level of education a limiting factor for asthma control in a population with access to pulmonologists and to treatment?
Conclusions: Among asthma patients with access to pulmonologists and to treatment, a low level of education does not appear to be a limiting factor for adequate asthma control.RESUMO Objetivo: Avaliar se a baixa escolaridade é um fator de risco para asma não controlada em uma população de pacientes que tem acesso a um pneumologista e ao tratamento. Métodos: Estudo transversal com pacientes com diagnóstico de asma, com idade> 10 anos, acompanhados por ao menos tr ês meses por um pneumologista em ambulatórios na cidade de Jundiaí (SP). Os indivíduos resp...
Source: Jornal Brasileiro de Pneumologia - February 11, 2019 Category: Respiratory Medicine Source Type: research

Prevalence of vitamin D deficiency and its relationship with factors associated with recurrent wheezing
Conclusions: The prevalence of vitamin D deficiency/insufficiency was high in our sample. Vitamin D concentrations were directly associated with vitamin D supplementation until 2 years of age and were inversely associated with wheezing events in the first year of life, personal history of atopic dermatitis, and environmental pollution.RESUMO Objetivo: Determinar a preval ência da deficiência/insuficiência de vitamina D em indivíduos com sibilância recorrente e/ou asma com idade de 0-18 anos e residentes na microrregião de Viçosa (MG) atendidos em um centro de referência e ...
Source: Jornal Brasileiro de Pneumologia - February 11, 2019 Category: Respiratory Medicine Source Type: research

Back to the future: a case series of minimally invasive repair of pectus excavatum with regular instruments
Conclusions: In this preliminary study, the rate of complications associated with MIRPERI was comparable to that reported in the literature for MIRPE. The MIRPERI approach has the potential to improve the safety of PE repair, particularly for surgeons that do not have access to certain special instruments or have not been trained in their use.RESUMO Objetivo: O minimally invasive repair of pectus excavatum (MIRPE, reparo minimamente invasivo do pectus excavatum) é um tratamento cirúrgico do PE. Durante o procedimento, utiliza-se um introdutor específico a fim de criar um túnel mediastinal para a...
Source: Jornal Brasileiro de Pneumologia - February 11, 2019 Category: Respiratory Medicine Source Type: research

Obstructive sleep apnea and quality of life in elderly patients with a pacemaker
Conclusions: In elderly patients with a pacemaker, OSA was not found to be associated with quality of life or with symptoms of anxiety or depression.RESUMO Objetivo: Avaliar a qualidade de vida em idosos portadores de marca-passo e apneia obstrutiva do sono (AOS). M étodos: Estudo de corte transversal com idosos (idade ≥ 60 anos) portadores de marca-passo card íaco. A variável dependente foi qualidade de vida, avaliada por meio do Medical Outcomes Study 36-item Short-Form Health Survey (SF-36). Dados sociodemográficos e clínicos foram analisados como variáveis independentes, ent...
Source: Jornal Brasileiro de Pneumologia - February 11, 2019 Category: Respiratory Medicine Source Type: research

Management of COPD within the Brazilian Unified Health Care System in the state of Bahia: an analysis of real-life medication use patterns
Conclusions: Long-acting bronchodilators are frequently underused in individuals with moderate to very severe COPD within the Brazilian Unified Health Care System in the state of Bahia. Most patients in our sample were treated inappropriately, and undertreatment predominated. Strategies to improve access to long-acting bronchodilators and the quality of COPD pharmacological management are required.RESUMO Objetivo: Descrever o padr ão de tratamento farmacológico da DPOC no estado da Bahia e avaliar a conformidade desse padrão com diretrizes clínicas de manejo da doença. Métodos: Est...
Source: Jornal Brasileiro de Pneumologia - February 11, 2019 Category: Respiratory Medicine Source Type: research

Erratum
ABSTRACT Obesity hypoventilation syndrome (OHS) is defined as the presence of obesity (body mass index ≥ 30 kg/m ²) and daytime arterial hypercapnia (PaCO2 ≥ 45 mmHg) in the absence of other causes of hypoventilation. OHS is often overlooked and confused with other conditions associated with hypoventilation, particularly COPD. The recognition of OHS is important because of its high prevalence and the fact that, if left untreated, it is associated with high morbidity and mortality. In the present review, we address recent advances in the pathophysiology and management of OHS, the usefulness of determination of ve...
Source: Jornal Brasileiro de Pneumologia - January 31, 2019 Category: Respiratory Medicine Source Type: research

Empyema caused by infection with Clostridium septicum in a patient with lung cancer
ABSTRACT Obesity hypoventilation syndrome (OHS) is defined as the presence of obesity (body mass index ≥ 30 kg/m ²) and daytime arterial hypercapnia (PaCO2 ≥ 45 mmHg) in the absence of other causes of hypoventilation. OHS is often overlooked and confused with other conditions associated with hypoventilation, particularly COPD. The recognition of OHS is important because of its high prevalence and the fact that, if left untreated, it is associated with high morbidity and mortality. In the present review, we address recent advances in the pathophysiology and management of OHS, the usefulness of determination of ve...
Source: Jornal Brasileiro de Pneumologia - January 31, 2019 Category: Respiratory Medicine Source Type: research

Near-fatal pulmonary embolism: capnographic perspective
ABSTRACT Obesity hypoventilation syndrome (OHS) is defined as the presence of obesity (body mass index ≥ 30 kg/m ²) and daytime arterial hypercapnia (PaCO2 ≥ 45 mmHg) in the absence of other causes of hypoventilation. OHS is often overlooked and confused with other conditions associated with hypoventilation, particularly COPD. The recognition of OHS is important because of its high prevalence and the fact that, if left untreated, it is associated with high morbidity and mortality. In the present review, we address recent advances in the pathophysiology and management of OHS, the usefulness of determination of ve...
Source: Jornal Brasileiro de Pneumologia - January 31, 2019 Category: Respiratory Medicine Source Type: research

Eosinophilic pneumonia: remember topical drugs as a potential etiology
ABSTRACT Obesity hypoventilation syndrome (OHS) is defined as the presence of obesity (body mass index ≥ 30 kg/m ²) and daytime arterial hypercapnia (PaCO2 ≥ 45 mmHg) in the absence of other causes of hypoventilation. OHS is often overlooked and confused with other conditions associated with hypoventilation, particularly COPD. The recognition of OHS is important because of its high prevalence and the fact that, if left untreated, it is associated with high morbidity and mortality. In the present review, we address recent advances in the pathophysiology and management of OHS, the usefulness of determination of ve...
Source: Jornal Brasileiro de Pneumologia - January 31, 2019 Category: Respiratory Medicine Source Type: research

Pulmonary involvement in Crohn’s disease
ABSTRACT Obesity hypoventilation syndrome (OHS) is defined as the presence of obesity (body mass index ≥ 30 kg/m ²) and daytime arterial hypercapnia (PaCO2 ≥ 45 mmHg) in the absence of other causes of hypoventilation. OHS is often overlooked and confused with other conditions associated with hypoventilation, particularly COPD. The recognition of OHS is important because of its high prevalence and the fact that, if left untreated, it is associated with high morbidity and mortality. In the present review, we address recent advances in the pathophysiology and management of OHS, the usefulness of determination of ve...
Source: Jornal Brasileiro de Pneumologia - January 31, 2019 Category: Respiratory Medicine Source Type: research

Obesity hypoventilation syndrome: a current review
ABSTRACT Obesity hypoventilation syndrome (OHS) is defined as the presence of obesity (body mass index ≥ 30 kg/m ²) and daytime arterial hypercapnia (PaCO2 ≥ 45 mmHg) in the absence of other causes of hypoventilation. OHS is often overlooked and confused with other conditions associated with hypoventilation, particularly COPD. The recognition of OHS is important because of its high prevalence and the fact that, if left untreated, it is associated with high morbidity and mortality. In the present review, we address recent advances in the pathophysiology and management of OHS, the usefulness of determination of ve...
Source: Jornal Brasileiro de Pneumologia - January 31, 2019 Category: Respiratory Medicine Source Type: research

Proportional weight loss in six months as a risk factor for mortality in stage IV non-small cell lung cancer
ABSTRACT Objective: To evaluate different weight loss (WL) cut-off points as prognostic markers of 3-month survival after diagnosis of stage IV non-small cell lung cancer (NSCLC). Methods: This was a prospective study involving 104 patients with metastatic (stage IV) NSCLC who were admitted to a cancer treatment center in southern Brazil between January of 2014 and November of 2016. We evaluated total WL and WL per month, as well as WL and WL per month in the 6 months preceding the diagnosis. The patients were followed for 3 months after diagnosis. A Cox proportional hazards regression model and Kaplan-Meier curves were us...
Source: Jornal Brasileiro de Pneumologia - January 31, 2019 Category: Respiratory Medicine Source Type: research

Genetic and phenotypic traits of children and adolescents with cystic fibrosis in Southern Brazil
Conclusions: The mutations of CFTR identified more frequently were F508del and G542X. These are type II and I mutations, respectively. Along with type III, they present a more severe cystic fibrosis phenotype. More than half of the sample (52.38%) presented homozygous mutation for F508del, that is, patients who could be treated with Lumacaftor/Ivacaftor. Approximately 7% of the patients (7.14%) presented type III and IV mutations, therefore becoming candidates for the treatment with Ivacaftor.RESUMO Objetivos: Caracterizar as principais muta ções identificadas no cystic fibrosis transmembrane conductance regu...
Source: Jornal Brasileiro de Pneumologia - January 31, 2019 Category: Respiratory Medicine Source Type: research

Trend of self-reported asthma prevalence in Brazil from 2003 to 2013 in adults and factors associated with prevalence
ABSTRACT Objectives: To determine the trend of self-reported asthma diagnosed prevalence and to describe the factors associated with asthma in Brazilian adults. Method: Epidemiological cross-sectional study based on databases analysis from three national household surveys: Pesquisa Nacional por Amostra de Domic ílios (PNAD) 2003, PNAD 2008 and Pesquisa Nacional de Saúde (PNS) 2013. Participants between 18-45 years old were included. Trend analysis of asthma diagnosed prevalence was conducted using a logistic general linear model. A hierarchical logistic regression model was used to select factors signifi cant...
Source: Jornal Brasileiro de Pneumologia - January 31, 2019 Category: Respiratory Medicine Source Type: research

Mitomycin C in the endoscopic treatment of tracheal stenosis: a prospective cohort study
Conclusions: MMC appears to be effective in the endoscopic treatment of tracheal stenosis.RESUMO Objetivo: Avaliar a efic ácia da mitomicina C (MMC) no tratamento endoscópico de estenose traqueal. Métodos: Pacientes com estenose laringotraqueal, traqueal ou traqueobrônquica foram tratados por meio de dilatação e MMC tópica. Foram empregados os seguintes critérios de inclusão: pacientes inaptos para cirurgia ( por motivos médicos) no momento da avaliação; estenose membranosa com boa resposta a dilatação e estenose pós-ope...
Source: Jornal Brasileiro de Pneumologia - January 31, 2019 Category: Respiratory Medicine Source Type: research

Self-reported smoking status and urinary cotinine levels in patients with asthma
Conclusions: Former smoking is associated with severe asthma. Current smoking is observed in patients with severe asthma, and patient nondisclosure of smoking status occurs in some cases. Patients with severe asthma should be thoroughly screened for smoking, and findings should be complemented by objective testing.RESUMO Objetivo: Descrever a frequ ência de tabagismo ativo entre pacientes com asma e indivíduos sem asma, usando questionários padronizados e dosagem da cotinina urinária. Métodos: Estudo transversal realizado em Salvador (BA), com 1.341 indivíduos, sendo 498 com asma gr...
Source: Jornal Brasileiro de Pneumologia - January 31, 2019 Category: Respiratory Medicine Source Type: research

Impact of thoracic radiotherapy on respiratory function and exercise capacity in patients with breast cancer
ABSTRACT Objective: To evaluate the impact of thoracic radiotherapy on respiratory function and exercise capacity in patients with breast cancer. Methods: Breast cancer patients in whom thoracic radiotherapy was indicated after surgical treatment and chemotherapy were submitted to HRCT, respiratory evaluation, and exercise capacity evaluation before radiotherapy and at three months after treatment completion. Respiratory muscle strength testing, measurement of chest wall mobility, and complete pulmonary function testing were performed for respiratory evaluation; cardiopulmonary exercise testing was performed to evaluate ex...
Source: Jornal Brasileiro de Pneumologia - January 31, 2019 Category: Respiratory Medicine Source Type: research

Prevalence of latent Mycobacterium tuberculosis infection in renal transplant recipients
Conclusions: The prevalence of LTBI was low in this sample of renal transplant recipients. The TST should be administered if renal graft function is preserved. A second TST should be administered if the first TST is negative.RESUMO Objetivo: Estimar a preval ência da infecção latente por Mycobacterium tuberculosis (ILTB) em transplantados renais e avaliar as associações sociodemográficas, comportamentais e clínicas com a prova tuberculínica (PT) positiva. Métodos: Estudo transversal, com pacientes com idade ≥ 18 anos, transplantados renais no Centro de Transp...
Source: Jornal Brasileiro de Pneumologia - January 31, 2019 Category: Respiratory Medicine Source Type: research

Longitudinal follow-up of cardiac vagal activity in individuals undergoing endoscopic thoracic sympathectomy
Conclusions: At one month after sympathectomy for primary hyperhidrosis, patients present with changes in resting HR and CVA, both of which tend to return to baseline at four years after surgery.RESUMO Objetivo: Investigar longitudinalmente o comportamento da atividade vagal card íaca (AVC) por meio da FC de repouso e do índice vagal cardíaco (IVC) de indivíduos submetidos à simpatectomia para o tratamento de hiperidrose primária. Métodos: Estudo de natureza descritiva e longitudinal que avaliou 22 pacientes (13 mulheres), com média de idade de 22,5 ± 8,8 anos....
Source: Jornal Brasileiro de Pneumologia - January 31, 2019 Category: Respiratory Medicine Source Type: research

Spirometry reference values for Black adults in Brazil
Conclusions: The fact that the predicted spirometry values derived for the population of Black adults in Brazil were lower than those previously derived for White adults in the country justifies the use of an equation specific to the former population.RESUMO Objetivo: Derivar equa ções de referência para a espirometria forçada em adultos brasileiros negros, saudáveis, que nunca fumaram, e comparar os resultados com os valores previstos para a raça branca publicados em 2007. Métodos: Os exames seguiram as normas recomendadas pela Sociedade Brasileira de Pneumologia e T isiolog...
Source: Jornal Brasileiro de Pneumologia - January 31, 2019 Category: Respiratory Medicine Source Type: research

Critical appraisal of the literature. Why do we care?
(Source: Jornal Brasileiro de Pneumologia)
Source: Jornal Brasileiro de Pneumologia - January 31, 2019 Category: Respiratory Medicine Source Type: research

Pleural calcifications
(Source: Jornal Brasileiro de Pneumologia)
Source: Jornal Brasileiro de Pneumologia - January 31, 2019 Category: Respiratory Medicine Source Type: research

The need for a balance between highly prevalent diseases and neglected diseases
(Source: Jornal Brasileiro de Pneumologia)
Source: Jornal Brasileiro de Pneumologia - January 31, 2019 Category: Respiratory Medicine Source Type: research

Lung transplantation with extracorporeal membrane oxygenation as intraoperative support
ABSTRACT The study of the human microbiome-and, more recently, that of the respiratory system-by means of sophisticated molecular biology techniques, has revealed the immense diversity of microbial colonization in humans, in human health, and in various diseases. Apparently, contrary to what has been believed, there can be nonpathogenic colonization of the lungs by microorganisms such as bacteria, fungi, and viruses. Although this physiological lung microbiome presents low colony density, it presents high diversity. However, some pathological conditions lead to a loss of that diversity, with increasing concentrations of so...
Source: Jornal Brasileiro de Pneumologia - December 12, 2018 Category: Respiratory Medicine Source Type: research

Omalizumab as add-on therapy in patients with asthma and allergic bronchopulmonary aspergillosis
ABSTRACT The study of the human microbiome-and, more recently, that of the respiratory system-by means of sophisticated molecular biology techniques, has revealed the immense diversity of microbial colonization in humans, in human health, and in various diseases. Apparently, contrary to what has been believed, there can be nonpathogenic colonization of the lungs by microorganisms such as bacteria, fungi, and viruses. Although this physiological lung microbiome presents low colony density, it presents high diversity. However, some pathological conditions lead to a loss of that diversity, with increasing concentrations of so...
Source: Jornal Brasileiro de Pneumologia - December 12, 2018 Category: Respiratory Medicine Source Type: research

Smoking cessation before initiation of chemotherapy in metastatic non-small cell lung cancer: influence on prognosis
ABSTRACT The study of the human microbiome-and, more recently, that of the respiratory system-by means of sophisticated molecular biology techniques, has revealed the immense diversity of microbial colonization in humans, in human health, and in various diseases. Apparently, contrary to what has been believed, there can be nonpathogenic colonization of the lungs by microorganisms such as bacteria, fungi, and viruses. Although this physiological lung microbiome presents low colony density, it presents high diversity. However, some pathological conditions lead to a loss of that diversity, with increasing concentrations of so...
Source: Jornal Brasileiro de Pneumologia - December 12, 2018 Category: Respiratory Medicine Source Type: research

Clinical aspects of the Mycobacterium abscessus complex
ABSTRACT The study of the human microbiome-and, more recently, that of the respiratory system-by means of sophisticated molecular biology techniques, has revealed the immense diversity of microbial colonization in humans, in human health, and in various diseases. Apparently, contrary to what has been believed, there can be nonpathogenic colonization of the lungs by microorganisms such as bacteria, fungi, and viruses. Although this physiological lung microbiome presents low colony density, it presents high diversity. However, some pathological conditions lead to a loss of that diversity, with increasing concentrations of so...
Source: Jornal Brasileiro de Pneumologia - December 12, 2018 Category: Respiratory Medicine Source Type: research

Hamman’s syndrome
ABSTRACT The study of the human microbiome-and, more recently, that of the respiratory system-by means of sophisticated molecular biology techniques, has revealed the immense diversity of microbial colonization in humans, in human health, and in various diseases. Apparently, contrary to what has been believed, there can be nonpathogenic colonization of the lungs by microorganisms such as bacteria, fungi, and viruses. Although this physiological lung microbiome presents low colony density, it presents high diversity. However, some pathological conditions lead to a loss of that diversity, with increasing concentrations of so...
Source: Jornal Brasileiro de Pneumologia - December 12, 2018 Category: Respiratory Medicine Source Type: research