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Total 46 results found since Jan 2013.

58P Risk factors for immune related adverse events: A retrospective study
ConclusionThis study helped distinguish potential risk factors for irAE, like the female gender and history of allergies. Autoimmune disorders are already reported as risk factores. However the small sample isn't enough for us to draw accurate conclusions. More prospective trials are waranted in this setting.Legal entity responsible for the studyThe authors.FundingHas not received any funding.DisclosureAll authors have declared no conflicts of interest.
Source: Annals of Oncology - December 15, 2019 Category: Cancer & Oncology Source Type: research

The association between allergic diseases and cancer: a systematic review of the literature.
CONCLUSION: Overall, allergic diseases are inversely associated with the risk of cancers. PMID: 30895928 [PubMed - in process]
Source: The Netherlands Journal of Medicine - January 31, 2019 Category: General Medicine Authors: Karim AF, Westenberg LEH, Eurelings LEM, Otten R, Gerth van Wijk R Tags: Neth J Med Source Type: research

Residential Air Pollution and Associations with Wheeze and Shortness of Breath in Adults: A Combined Analysis of Cross-Sectional Data from Two Large European Cohorts
Conclusion: Exposure to PM and NO2 air pollution was associated with the prevalence of wheeze and shortness of breath in this large study, with stronger associations between PM2.5 and both outcomes among lower- versus higher-income participants. https://doi.org/10.1289/EHP1353 Received: 13 November 2016 Revised: 10 August 2017 Accepted: 14 August 2017 Published: 29 September 2017 Address correspondence to D. Doiron, Research Institute of the McGill University Health Centre, 2155 rue Guy, office 458, Montreal, Canada, H3H 2R9. Telephone: 1-514-934-1934 (ex. 71688). Email: ddoiron@maelstrom-research.org Supplemental Ma...
Source: EHP Research - September 29, 2017 Category: Environmental Health Authors: Daniil Lyalko Tags: Research Source Type: research

Updated Global Estimates of Respiratory Mortality in Adults ≥ 30 Years of Age Attributable to Long-Term Ozone Exposure
Conclusions: These findings suggest that the potential magnitude of health benefits of air quality policies targeting O3, health co-benefits of climate mitigation policies, and health implications of climate change-driven changes in O3 concentrations, are larger than previously thought. https://doi.org/10.1289/EHP1390 Received: 17 November 2016 Revised: 19 June 2017 Accepted: 20 June 2017 Published: 28 August 2017 Address correspondence to C.S. Malley, Stockholm Environment Institute, Environment Dept., Environment Building, Wentworth Way, University of York, York, YO10 5NG, UK. Telephone: 44 1904 323685. Email: chri...
Source: EHP Research - August 28, 2017 Category: Environmental Health Authors: Daniil Lyalko Tags: Research Source Type: research

Reflections on the history of indoor air science, focusing on the last 50  years
Abstract The scientific articles and Indoor Air conference publications of the indoor air sciences (IAS) during the last 50 years are summarized. In total 7524 presentations, from 79 countries, have been made at Indoor Air conferences held between 1978 (49 presentations) and 2014 (1049 presentations). In the Web of Science, 26 992 articles on indoor air research (with the word “indoor” as a search term) have been found (as of 1 Jan 2016) of which 70% were published during the last 10 years. The modern scientific history started in the 1970s with a question: “did indoor air pose a threat to health as did outdoor ai...
Source: Indoor Air - February 26, 2017 Category: Occupational Health Authors: J. Sundell Tags: ORIGINAL ARTICLE Source Type: research

Reflections on the history of indoor air science, focusing on the last 50 years
This article is protected by copyright. All rights reserved.
Source: Indoor Air - December 31, 2016 Category: Occupational Health Authors: Jan Sundell Tags: Original Article Source Type: research

Abstract IA03: Genetic and non-genetic risk factors of pancreatic cancer
In the United States, incidence and mortality rates of pancreatic cancer (PC) have remained largely unchanged since 1973. During 2005-2009, the incidence rate for Whites was 11.6/105 and for African-Americans, 15.2/105. Mortality rates were 10.7/105 for Whites and 13.8/105 for African-Americans. The 5-year survival has been 4-7% for decades. The absolute number of new cases and deaths due to PC has been increasing steadily since 2004 due to the baby-boomer generation reaching the risk window (where median age at diagnosis is 71 years). By 2030, PC will be the second most common cause of cancer mortality, after lung cancer....
Source: Cancer Research - December 13, 2016 Category: Cancer & Oncology Authors: Gloria M. Petersen Tags: Epidemiology and Risk Factors Source Type: research

Take a Deep Breath? But 9 in 10 People Worldwide Live with Excessive Air Pollution!
This report provides fresh information on the region’s emerging environmental issues and it will help governments shape their future policy,” said UNECE Executive Secretary Christian Friis Bach.Other challenges discussed in the assessment include climate change, considered one of the largest threats to human and ecosystem health, and to achieving sustainable development in the pan-European region.“It is also an accelerator for most other environmental risks, with impacts affecting health through floods, heat waves, droughts, reduced agricultural productivity, exacerbated air pollution and allergies and vector, food a...
Source: IPS Inter Press Service - Health - September 29, 2016 Category: Global & Universal Authors: Baher Kamal Tags: Climate Change Featured Global Headlines Health IPS UN: Inside the Glasshouse Source Type: news

From acid reflux to allergies, we reveal what's causing YOUR persistent cough
Most persistent coughs are caused by gastric reflux, which makes the upper airways hypersensitive. But some can be caused by asthma, a side effect of medication, an infection - or even lung cancer.
Source: the Mail online | Health - June 14, 2016 Category: Consumer Health News Source Type: news

Lung Cancer and Exposure to Nitrogen Dioxide and Traffic: A Systematic Review and Meta-Analysis
Conclusion: We found consistent evidence of a relationship between NO2, as a proxy for traffic-sourced air pollution exposure, with lung cancer. Studies of lung cancer related to residential proximity to roadways and NOx also suggest increased risk, which may be attributable partly to air pollution exposure. The International Agency for Research on Cancer recently classified outdoor air pollution and particulate matter as carcinogenic (Group 1). These meta-analyses support this conclusion, drawing particular attention to traffic-sourced air pollution. Citation: Hamra GB, Laden F, Cohen AJ, Raaschou-Nielsen O, Brauer...
Source: EHP Research - November 2, 2015 Category: Environmental Health Authors: Sam Duvall Tags: Review November 2015 Source Type: research

Chronic respiratory diseases and lung cancer research: a perspective from the European Union
Chronic respiratory diseases (CRDs) are chronic diseases of the airways and other structures of the lungs. Major CRDs are asthma and respiratory allergies, chronic obstructive pulmonary disease (COPD), occupational lung diseases, sleep apnoea syndrome and pulmonary hypertension. Globally, they affect 1 billion people and account for 7% of all deaths worldwide (4.2 million deaths) [1]. Lung cancer adds to this number another 1.4 million deaths annually (2.4%) [2]. Of the communicable lung diseases, tuberculosis is by far the most important. In 2012, 1.3 million people were killed by tuberculosis and 8.6 million new cases re...
Source: European Respiratory Journal - October 31, 2015 Category: Respiratory Medicine Authors: Navarro-Torne, A., Vidal, M., Trzaska, D. K., Passante, L., Crisafulli, A., Laang, H., van de Loo, J.-W., Berkouk, K., Draghia-Akli, R. Tags: Lung cancer Original Articles: European Lung Corner Source Type: research

Impact of air quality on lung health: myth or reality?
The respiratory system is a primary target of the harmful effects of key air pollutants of health concern. Several air pollutants have been implicated including particulate matter (PM), ozone (O3), nitrogen dioxide (NO2) polycyclic aromatic hydrocarbons (PAHs) and volatile organic compounds (VOCs). It is well known that episodes of exposure to high concentrations of outdoor air pollutants can cause acute respiratory exacerbations. However, there is now increasing evidence suggesting that significant exposure to outdoor air pollutants may be also associated with development of lung cancer and with incident cases of chronic ...
Source: Therapeutic Advances in Chronic Disease - August 25, 2015 Category: Internal Medicine Authors: Marino, E., Caruso, M., Campagna, D., Polosa, R. Tags: Reviews Source Type: research

Emerging allergies to cannabis
We report 6 clinical cases of immediate hypersensitivity related to CS.Subjects were young adults (27-41 years; 2M/4F) current or former C smokers. Symptoms were:plant food allergies due to cross-reactive lipid transfer proteins (LTP) (n= 5) (Metz-Favre C et al. Eur Ann Allergy Clin Immunol. 2011 Dec;43(6):193-5), rhinitis/asthma (n= 3), contact urticaria/eczema (n=3) and effort anaphylaxis (n=1). All had positive CS sIgE (median 8.05 (4.35-21.9) kU/L) (Ebo D et al. Int Arch Allergy Immunol. 2013;161:220-8). In 1 case, SPT with crude CS was made and strongly positive. All subjects were atopic.Up to now, C consumption has b...
Source: European Respiratory Journal - December 23, 2014 Category: Respiratory Medicine Authors: Doyen, V., Debaugnies, F., Ledent, C., Corazza, F., Michel, O., Mairesse, M. Tags: 5.3 Allergy and Immunology Source Type: research

Effects of antioxidant supplements and nutrients on patients with asthma and allergies.
Abstract Asthma and allergic diseases have become a worldwide public health concern because of their increased prevalence. Despite decades of research on risk factors, the causes of these disorders are poorly understood. They are thought to develop through complex interactions between genetic and environmental factors. Because pulmonary and systemic oxidative stress increase inflammatory responses relevant to asthma and allergy, dietary or vitamin supplementation with antioxidants (a broad and varied category) has been proposed as an approach to reducing asthma incidence or morbidity. Meta-analyses of observationa...
Source: Clinical Lung Cancer - May 1, 2014 Category: Cancer & Oncology Authors: Moreno-Macias H, Romieu I Tags: J Allergy Clin Immunol Source Type: research

RIsk of Cancer in Patients with Medically Diagnosed Hay Fever or Allergic Rhinitis
ABSTRACT Data on allergic conditions as risk or protective factors for cancer are controversial probably because most studies have used self‐reported data on mixed groups of allergies in a case‐control setting. We define cancer risks in medically diagnosed hay fever/allergic rhinitis patients in a nationwide cohort study. A total of 138,723 hay fever/allergic rhinitis patients were identified from three Swedish health care databases and standardized incidence ratios (SIRs) were calculated for subsequent cancers identified from the Swedish Cancer Registry. Overall cancer risk was not changed (SIR 1.03). For individual c...
Source: International Journal of Cancer - April 2, 2014 Category: Cancer & Oncology Authors: Kari Hemminki, Asta Försti, Mahdi Fallah, Jan Sundquist, Kristina Sundquist, Jianguang Ji Tags: Epidemiology Source Type: research