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Divisive normalization processors in the early visual system of the Drosophila brain
Biol Cybern. 2023 Sep 13. doi: 10.1007/s00422-023-00972-x. Online ahead of print.ABSTRACTDivisive normalization is a model of canonical computation of brain circuits. We demonstrate that two cascaded divisive normalization processors (DNPs), carrying out intensity/contrast gain control and elementary motion detection, respectively, can model the robust motion detection realized by the early visual system of the fruit fly. We first introduce a model of elementary motion detection and rewrite its underlying phase-based motion detection algorithm as a feedforward divisive normalization processor. We then cascade the DNP model...
Source: Biological Cybernetics - September 13, 2023 Category: Science Authors: Aurel A Lazar Yiyin Zhou Source Type: research

Quercetin attenuates environmental Avermectin-induced ROS accumulation and alleviates gill damage in carp through activation of the Nrf2 pathway
In this study, four groups were created: the Control group, the Que group (400 mg/kg), the AVM group (2.404 μg/L), and the Que plus AVM group. The analytical methods used in this study were pathological structure examination, QPCR, Reactive Oxygen Species (ROS) and Western blot. The results showed that Que alleviated AVM-induced oxidative stress, inflammatory damage and apoptosis in the gill tissues of carp by activating the Nrf2 pathway. The mechanism was that Que alleviated the accumulation of ROS, reduced the balance between oxidation and antioxidant disrupted by AVM exposure, lowered the content of lipid peroxidation ...
Source: Comparative biochemistry and physiology. Toxicology and pharmacology : CBP - September 13, 2023 Category: Biochemistry Authors: Mengyuan Zhou Jingchao Qiang Jiajie Gan Xuhui Xu Xing Li Shuai Zhang Baoshi Xu Zibo Dong Source Type: research

Divisive normalization processors in the early visual system of the Drosophila brain
Biol Cybern. 2023 Sep 13. doi: 10.1007/s00422-023-00972-x. Online ahead of print.ABSTRACTDivisive normalization is a model of canonical computation of brain circuits. We demonstrate that two cascaded divisive normalization processors (DNPs), carrying out intensity/contrast gain control and elementary motion detection, respectively, can model the robust motion detection realized by the early visual system of the fruit fly. We first introduce a model of elementary motion detection and rewrite its underlying phase-based motion detection algorithm as a feedforward divisive normalization processor. We then cascade the DNP model...
Source: Biological Cybernetics - September 13, 2023 Category: Science Authors: Aurel A Lazar Yiyin Zhou Source Type: research

Identification strategy of Fructus Gardeniae and its adulterant based on UHPLC/Q-orbitrap-MS and UHPLC-QTRAP-MS/MS combined with PLS regression model
Talanta. 2023 Sep 3;267:125136. doi: 10.1016/j.talanta.2023.125136. Online ahead of print.ABSTRACTFructus Gardeniae (FG) is the desiccative and ripe fruits of Gardenia jasminoides Ellis in the Rubiaceae family, which is a commonly used in traditional Chinese medicine (TCM) for clearing away heat, detoxification, relieving restlessness, and eliminating blood stasis. At the same time, it has also been announced as the first batch of TCM with homology of medicine and food. Fructus Gardeniae Grandiflorae (FGG), the fruit of Gardenia jasminoides Ellis var. grandiflora Nakai (Rubiaceae), is a common counterfeit herbal medicine o...
Source: Talanta - September 13, 2023 Category: Chemistry Authors: Xue Zhang Lei Wang Rongrong Li Liming Wang Zhifei Fu Feng He Erwei Liu Lifeng Han Source Type: research

Exploring food intake networks and anhedonia symptoms in a Chilean Adults sample
CONCLUSIONS: Subjects with anhedonia symptoms have a more central consumption of foods with a high or medium glycemic index compared to subjects without anhedonia symptoms, which could trigger the development of chronic diet-related diseases.PMID:37704006 | DOI:10.1016/j.appet.2023.107042
Source: Appetite - September 13, 2023 Category: Nutrition Authors: Leslie Landaeta-D íaz Samuel Dur án-Agüero Gabriel Gonz ález-Medina Source Type: research

Quercetin attenuates environmental Avermectin-induced ROS accumulation and alleviates gill damage in carp through activation of the Nrf2 pathway
In this study, four groups were created: the Control group, the Que group (400 mg/kg), the AVM group (2.404 μg/L), and the Que plus AVM group. The analytical methods used in this study were pathological structure examination, QPCR, Reactive Oxygen Species (ROS) and Western blot. The results showed that Que alleviated AVM-induced oxidative stress, inflammatory damage and apoptosis in the gill tissues of carp by activating the Nrf2 pathway. The mechanism was that Que alleviated the accumulation of ROS, reduced the balance between oxidation and antioxidant disrupted by AVM exposure, lowered the content of lipid peroxidation ...
Source: Comparative biochemistry and physiology. Toxicology and pharmacology : CBP - September 13, 2023 Category: Biochemistry Authors: Mengyuan Zhou Jingchao Qiang Jiajie Gan Xuhui Xu Xing Li Shuai Zhang Baoshi Xu Zibo Dong Source Type: research

Divisive normalization processors in the early visual system of the Drosophila brain
Biol Cybern. 2023 Sep 13. doi: 10.1007/s00422-023-00972-x. Online ahead of print.ABSTRACTDivisive normalization is a model of canonical computation of brain circuits. We demonstrate that two cascaded divisive normalization processors (DNPs), carrying out intensity/contrast gain control and elementary motion detection, respectively, can model the robust motion detection realized by the early visual system of the fruit fly. We first introduce a model of elementary motion detection and rewrite its underlying phase-based motion detection algorithm as a feedforward divisive normalization processor. We then cascade the DNP model...
Source: Biological Cybernetics - September 13, 2023 Category: Science Authors: Aurel A Lazar Yiyin Zhou Source Type: research

Quercetin attenuates environmental Avermectin-induced ROS accumulation and alleviates gill damage in carp through activation of the Nrf2 pathway
In this study, four groups were created: the Control group, the Que group (400 mg/kg), the AVM group (2.404 μg/L), and the Que plus AVM group. The analytical methods used in this study were pathological structure examination, QPCR, Reactive Oxygen Species (ROS) and Western blot. The results showed that Que alleviated AVM-induced oxidative stress, inflammatory damage and apoptosis in the gill tissues of carp by activating the Nrf2 pathway. The mechanism was that Que alleviated the accumulation of ROS, reduced the balance between oxidation and antioxidant disrupted by AVM exposure, lowered the content of lipid peroxidation ...
Source: Comparative biochemistry and physiology. Toxicology and pharmacology : CBP - September 13, 2023 Category: Biochemistry Authors: Mengyuan Zhou Jingchao Qiang Jiajie Gan Xuhui Xu Xing Li Shuai Zhang Baoshi Xu Zibo Dong Source Type: research

Divisive normalization processors in the early visual system of the Drosophila brain
Biol Cybern. 2023 Sep 13. doi: 10.1007/s00422-023-00972-x. Online ahead of print.ABSTRACTDivisive normalization is a model of canonical computation of brain circuits. We demonstrate that two cascaded divisive normalization processors (DNPs), carrying out intensity/contrast gain control and elementary motion detection, respectively, can model the robust motion detection realized by the early visual system of the fruit fly. We first introduce a model of elementary motion detection and rewrite its underlying phase-based motion detection algorithm as a feedforward divisive normalization processor. We then cascade the DNP model...
Source: Biological Cybernetics - September 13, 2023 Category: Science Authors: Aurel A Lazar Yiyin Zhou Source Type: research

Emergence of Marburg virus: a global perspective on fatal outbreaks and clinical challenges
The Marburg virus (MV), identified in 1967, has caused deadly outbreaks worldwide, the mortality rate of Marburg virus disease (MVD) varies depending on the outbreak and virus strain, but the average case fatality rate is around 50%. However, case fatality rates have varied from 24 to 88% in past outbreaks depending on virus strain and case management. Designated a priority pathogen by the National Institute of Allergy and Infectious Diseases (NIAID), MV induces hemorrhagic fever, organ failure, and coagulation issues in both humans and non-human primates. This review presents an extensive exploration of MVD outbreak evolu...
Source: Frontiers in Microbiology - September 13, 2023 Category: Microbiology Source Type: research

Molecules, Vol. 28, Pages 6604: Could Natural Products Help in the Control of Obesity? Current Insights and Future Perspectives
iawan Bonglee Kim Obesity is a global issue faced by many individuals worldwide. However, no drug has a pronounced effect with few side effects. Green tea, a well-known natural product, shows preventive effects against obesity by decreasing lipogenesis and increasing fat oxidation and antioxidant capacity. In contrast, other natural products are known to contribute to obesity. Relevant articles published on the therapeutic effect of natural products on obesity were retrieved from PubMed, Web of Science, and Scopus. The search was conducted by entering keywords such as “obesity”, &l...
Source: Molecules - September 13, 2023 Category: Chemistry Authors: Jiwon Park Fahrul Nurkolis Hyunji Won Jiye Yang Dayeon Oh Hyunkyung Jo Jinwon Choi Sanghyun Chung Rudy Kurniawan Bonglee Kim Tags: Review Source Type: research

The Use of Nanocarriers to Enhance the Anti-neuroinflammatory Potential of Dietary Flavonoids in Animal Models of Neurodegenerative Diseases: A Systematic Review
CONCLUSION: Nanoencapsulated flavonoids should, therefore, be considered a novel therapeutic approach for the treatment of NDs.PMID:37691188 | DOI:10.2174/1389557523666230907093441
Source: Mini Reviews in Medicinal Chemistry - September 11, 2023 Category: Chemistry Authors: Gopalsamy Rajiv Gandhi Varghese Edwin Hillary Kumaraswamy Athesh Maria Let ícia Carvalho da Cruz Ramos Gabriela Peres de Oliveira Krauss Gnanasekaran Jothi Gurunagarajan Sridharan Rengaraju Sivasubramanian Govindasamy Hariharan Alan Bruno Silva Vasconcel Source Type: research

The efficacy of digital media tools to promote a healthy diet in children: A systematic review of intervention studies
CONCLUSIONS: Digital media tools can be used to effectively implement health promotion interventions to improve knowledge and adherence to healthy diets in school-aged children. Further studies are needed to assess the long-term effectiveness of these interventions.PMID:37695189 | DOI:10.23750/abm.v94iS3.14293
Source: Acta Bio-Medica : Atenei Parmensis - September 11, 2023 Category: General Medicine Authors: Giulia Dallagiacoma Federica Alberti Anna Odone Source Type: research