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Current Diagnosis and Management of Familial Hypobetalipoproteinemia 1
J Atheroscler Thromb. 2024 May 3. doi: 10.5551/jat.RV22018. Online ahead of print.ABSTRACTFamilial hypobetalipoproteinemia (FHBL) 1 is a rare genetic disorder with an autosomal codominant mode of inheritance and is caused by defects in the apolipoprotein (apo) B (APOB) gene that disable lipoprotein formation. ApoB proteins are required for the formation of very low-density lipoproteins (VLDLs), chylomicrons, and their metabolites. VLDLs transport cholesterol and triglycerides from the liver to the peripheral tissues, whereas chylomicrons transport absorbed lipids and fat-soluble vitamins from the intestine. Homozygous or c...
Source: Journal of Atherosclerosis and Thrombosis - May 6, 2024 Category: Cardiology Authors: Tetsuji Wakabayashi Manabu Takahashi Hiroaki Okazaki Sachiko Okazaki Koutaro Yokote Hayato Tada Masatsune Ogura Yasushi Ishigaki Shizuya Yamashita Mariko Harada-Shiba Committee on Primary Dyslipidemia under the Research Program on Rare and Intractable Dis Source Type: research

Cholesterol Efflux Capacity and Its Association with Oxidative Stress in Myocardial Infarction
J Atheroscler Thromb. 2024 May 2. doi: 10.5551/jat.ED262. Online ahead of print.NO ABSTRACTPMID:38692903 | DOI:10.5551/jat.ED262 (Source: Journal of Atherosclerosis and Thrombosis)
Source: Journal of Atherosclerosis and Thrombosis - May 1, 2024 Category: Cardiology Authors: Yasuhiro Endo Kei Sasaki Katsunori Ikewaki Source Type: research

Japanese Diagnostic Criteria for Pediatric Familial Hypercholesterolemia 2022
J Atheroscler Thromb. 2024 May 2. doi: 10.5551/jat.ED259. Online ahead of print.NO ABSTRACTPMID:38692904 | DOI:10.5551/jat.ED259 (Source: Journal of Atherosclerosis and Thrombosis)
Source: Journal of Atherosclerosis and Thrombosis - May 1, 2024 Category: Cardiology Authors: Kazushige Dobashi Source Type: research

Twin Study: The Factors Affecting the Serum LDL-C and HDL-C Levels and an RNA-Seq Analysis in Mononuclear Cells in Monozygotic Twins
CONCLUSION: We identified the factors affecting the LDL-C or HDL-C levels in monozygotic twins. In addition, some types of inflammatory gene expression in peripheral blood mononuclear cells were suppressed in accordance with the HDL-C levels, thus suggesting the importance of weight management and exercise habits in addition to dietary instructions to control the LDL-C or HDL-C levels.PMID:38684403 | DOI:10.5551/jat.64882 (Source: Journal of Atherosclerosis and Thrombosis)
Source: Journal of Atherosclerosis and Thrombosis - April 29, 2024 Category: Cardiology Authors: Sae Nishihara Masahiro Koseki Katsunao Tanaka Takashi Omatsu Hiroshi Sawabe Hiroyasu Inui Ayami Saga Takeshi Okada Tomoaki Higo Tohru Ohama Makoto Nishida Yasushi Sakata Mikio Watanabe Osaka Twin Research Group Source Type: research

Prognostic Implications of the Acute Lipid Levels in Stroke Patients
J Atheroscler Thromb. 2024 Apr 23. doi: 10.5551/jat.ED261. Online ahead of print.NO ABSTRACTPMID:38658326 | DOI:10.5551/jat.ED261 (Source: Journal of Atherosclerosis and Thrombosis)
Source: Journal of Atherosclerosis and Thrombosis - April 24, 2024 Category: Cardiology Authors: Takao Hoshino Source Type: research