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Vaccination: Covid Vaccine
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Comparative effectiveness and duration of protection of ChAdOx1, CoronaVac, BNT162b2, mRNA-1273, and Ad26.COV2.S COVID-19 vaccines for symptomatic and hospitalized Mu, Delta, and Omicron: A test-negative case-control study
CONCLUSION: Our study provides further evidence on the protective effect of mRNA vaccines for Omicron, and warrant that the duration of protection against symptomatic infection may last for only a few months.PMID:37679278 | DOI:10.1016/j.vaccine.2023.08.072
Source: Vaccine - September 7, 2023 Category: Allergy & Immunology Authors: Angel Paternina-Caicedo David Santiago Quevedo Diana Sof ía Ríos Diane Moyano Nelson Alvis-Guzm án Nelson Rafael Alviz-Zakzuk Fernando Salcedo Lina Moyano Javier Ram írez-Suarez Adrian D Smith Fernando De la Hoz-Restrepo Source Type: research
When to be vaccinated? What to consider? Modelling decision-making and time preference for COVID-19 vaccine through a conjoint experiment
Vaccine. 2023 Sep 5:S0264-410X(23)01024-1. doi: 10.1016/j.vaccine.2023.08.068. Online ahead of print.ABSTRACTHow do citizens choose COVID-19 vaccines, and when do they wish to be vaccinated? A choice-based conjoint experiment was conducted in Hong Kong to examine factors that shape citizens' preference toward COVID-19 vaccines and their time preference to be vaccinated, which is overlooked in extant literature. Results suggest people are most concerned about vaccines' efficacy and severe side-effects, and that cash incentives are not useful in enhancing vaccine appeal. The majority of respondents show low intention for imm...
Source: Vaccine - September 7, 2023 Category: Allergy & Immunology Authors: Pak Hong Ricci Yue Hi Po Bobo Lau Siu Man Ng Lai Wan Cecilia Chan Samson Yuen Source Type: research
A standardised protocol for relative SARS-CoV-2 variant severity assessment, applied to Omicron BA.1 and Delta in six European countries, October 2021 to February 2022
In conclusion, this study demonstrates the feasibility of conducting variant severity analyses in a multinational collaborative framework and adds evidence for the reduced severity of the Omicron BA.1 variant.PMID:37676146 | PMC:PMC10486193 | DOI:10.2807/1560-7917.ES.2023.28.36.2300048
Source: Euro Surveill - September 7, 2023 Category: Infectious Diseases Authors: Tommy Nyberg Peter Bager Ingrid Bech Svalgaard Dritan Bejko Nick Bundle Josie Evans Tyra Grove Krause Jim McMenamin Jo ël Mossong Heather Mutch Ajibola Omokanye Andr é Peralta-Santos Pedro Pinto-Leite Jostein Starrfelt Simon Thelwall Lamprini Veneti Rob Source Type: research
COVID-19: An Overview of SARS-CoV-2 Variants-The Current Vaccines and Drug Development
Biomed Res Int. 2023 Aug 29;2023:1879554. doi: 10.1155/2023/1879554. eCollection 2023.ABSTRACTThe world is presently in crisis facing an outbreak of a health-threatening microorganism known as COVID-19, responsible for causing uncommon viral pneumonia in humans. The virus was first reported in Wuhan, China, in early December 2019, and it quickly became a global concern due to the pandemic. Challenges in this regard have been compounded by the emergence of several variants such as B.1.1.7, B.1.351, P1, and B.1.617, which show an increase in transmission power and resistance to therapies and vaccines. Ongoing researches are ...
Source: Biomed Res - September 7, 2023 Category: Research Authors: Narjess Bostanghadiri Pardis Ziaeefar Morvarid Golrokh Mofrad Parsa Yousefzadeh Ali Hashemi Davood Darban-Sarokhalil Source Type: research
Stimuli-Responsive Hydrogel Microcapsules Harnessing the COVID-19 Immune Response for Cancer Therapeutics
We present the development of stimuli-responsive microcapsules, loaded with a viral immunogenetic agent, harnessing the immune response against the Coronavirus Disease 2019, COVID-19, to selectively attack liver cancer cells (hepatoma) or recognize breast cancer or hepatoma, by expression of green fluorescence protein, GFP. The pH-responsive microcapsules, modified with DNA-tetrahedra nanostructures, increased hepatoma permeation by 50%. Incorporation of a GFP-encoding lentivirus vector inside the tumor-targeting pH-stimulated miRNA-triggered and Alpha-fetoprotein-dictated microcapsules enables the demonstration of neoplas...
Source: Angewandte Chemie - September 7, 2023 Category: Chemistry Authors: Amit Fischer Avner Ehrlich Yevgeni Plotkin Yu Ouyang Klil Asulin Ioannidis Konstantinos Chunhai Fan Yaakov Nahmias Itamar Willner Source Type: research
Determinants of post discharge mortality among hospitalized COVID-19 patients: Nested matched case-control analyses from the National Clinical Registry for COVID-19
CONCLUSIONS: : Prior vaccination protects against post discharge mortality till one year in hospitalized COVID-19 patients. PCC may have long term deleterious effects, including mortality, for which further research is warranted.PMID:37675689 | DOI:10.4103/ijmr.ijmr_973_23
Source: The Indian Journal of Medical Research - September 7, 2023 Category: Biomedical Science Authors: Gunjan Kumar Arunansu Talukdar Alka Turuk Ashish Bhalla Subhasis Mukherjee Pankaj Bhardwaj Tarun Bhatnagar Aparna Mukherjee Source Type: research
Getting Jab or Regular Test: Observations from an Impulsive Epidemic COVID-19 Model
This study proposes a population-based model that can accommodate different personal decision choices, such as getting vaccinated or undergoing regular tests, as well as vaccine efficacies and uncertainties in epidemic transmission. The model, formulated as impulsive differential equations, uses time instants to represent the reporting date for the test result of an unvaccinated individual. By employing well-accepted indices to measure transmission risk, including the basic reproduction number, the peak time, the final size, and the number of severe infections, the study shows that an optimal testing frequency is highly se...
Source: Bulletin of Mathematical Biology - September 7, 2023 Category: Bioinformatics Authors: Kaihui Liu Zhenguo Bai Daihai He Yijun Lou Source Type: research
Management of coronavirus disease 2019 vaccine-induced cutaneous complications: A comprehensive literature review
J Family Community Med. 2023 Jul-Sep;30(3):161-170. doi: 10.4103/jfcm.jfcm_3_23. Epub 2023 Jul 24.ABSTRACTDespite the numerous reports of cutaneous manifestations associated with vaccines for coronavirus disease 2019 (COVID-19), the relationship between COVID-19 vaccines and cutaneous side effects remains unevaluated. In this review, we examine these manifestations and their management. Reported dermatoses included injection-site reaction (early and delayed), type I allergic reaction, morbilliform eruption, pityriasis rosea, Sweet syndrome, lichen planus, psoriasis, herpes zoster reactivation, erythema multiforme, Stevens-...
Source: Herpes - September 7, 2023 Category: Infectious Diseases Authors: Nouf F Bin Rubaian Abdullah A Aljalfan Serene R Almuhaidib Source Type: research
Retinal vein occlusion following BNT162b2 (Pfizer-BioNTech) COVID-19 vaccination
Singapore Med J. 2023 Aug 22. doi: 10.4103/singaporemedj.SMJ-2021-430. Online ahead of print.NO ABSTRACTPMID:37675679 | DOI:10.4103/singaporemedj.SMJ-2021-430
Source: Singapore Medical Journal - September 7, 2023 Category: General Medicine Authors: Duoduo Wu Blanche Xiao Hong Lim Dawn Ka-Ann Lim Gopal Lingam Chris Hong Long Lim Source Type: research
A standardised protocol for relative SARS-CoV-2 variant severity assessment, applied to Omicron BA.1 and Delta in six European countries, October 2021 to February 2022
In conclusion, this study demonstrates the feasibility of conducting variant severity analyses in a multinational collaborative framework and adds evidence for the reduced severity of the Omicron BA.1 variant.PMID:37676146 | DOI:10.2807/1560-7917.ES.2023.28.36.2300048
Source: Euro Surveill - September 7, 2023 Category: Infectious Diseases Authors: Tommy Nyberg Peter Bager Ingrid Bech Svalgaard Dritan Bejko Nick Bundle Josie Evans Tyra Grove Krause Jim McMenamin Jo ël Mossong Heather Mutch Ajibola Omokanye Andr é Peralta-Santos Pedro Pinto-Leite Jostein Starrfelt Simon Thelwall Lamprini Veneti Rob Source Type: research
Determinants of post discharge mortality among hospitalized COVID-19 patients: Nested matched case-control analyses from the National Clinical Registry for COVID-19
CONCLUSIONS: : Prior vaccination protects against post discharge mortality till one year in hospitalized COVID-19 patients. PCC may have long term deleterious effects, including mortality, for which further research is warranted.PMID:37675689 | DOI:10.4103/ijmr.ijmr_973_23
Source: Indian J Med Res - September 7, 2023 Category: Research Authors: Gunjan Kumar Arunansu Talukdar Alka Turuk Ashish Bhalla Subhasis Mukherjee Pankaj Bhardwaj Tarun Bhatnagar Aparna Mukherjee Source Type: research
Comparative effectiveness and duration of protection of ChAdOx1, CoronaVac, BNT162b2, mRNA-1273, and Ad26.COV2.S COVID-19 vaccines for symptomatic and hospitalized Mu, Delta, and Omicron: A test-negative case-control study
CONCLUSION: Our study provides further evidence on the protective effect of mRNA vaccines for Omicron, and warrant that the duration of protection against symptomatic infection may last for only a few months.PMID:37679278 | DOI:10.1016/j.vaccine.2023.08.072
Source: Vaccine - September 7, 2023 Category: Allergy & Immunology Authors: Angel Paternina-Caicedo David Santiago Quevedo Diana Sof ía Ríos Diane Moyano Nelson Alvis-Guzm án Nelson Rafael Alviz-Zakzuk Fernando Salcedo Lina Moyano Javier Ram írez-Suarez Adrian D Smith Fernando De la Hoz-Restrepo Source Type: research
When to be vaccinated? What to consider? Modelling decision-making and time preference for COVID-19 vaccine through a conjoint experiment
Vaccine. 2023 Sep 5:S0264-410X(23)01024-1. doi: 10.1016/j.vaccine.2023.08.068. Online ahead of print.ABSTRACTHow do citizens choose COVID-19 vaccines, and when do they wish to be vaccinated? A choice-based conjoint experiment was conducted in Hong Kong to examine factors that shape citizens' preference toward COVID-19 vaccines and their time preference to be vaccinated, which is overlooked in extant literature. Results suggest people are most concerned about vaccines' efficacy and severe side-effects, and that cash incentives are not useful in enhancing vaccine appeal. The majority of respondents show low intention for imm...
Source: Vaccine - September 7, 2023 Category: Allergy & Immunology Authors: Pak Hong Ricci Yue Hi Po Bobo Lau Siu Man Ng Lai Wan Cecilia Chan Samson Yuen Source Type: research
Progress Toward Measles Elimination - African Region, 2017-2021
MMWR Morb Mortal Wkly Rep. 2023 Sep 8;72(36):985-991. doi: 10.15585/mmwr.mm7236a3.ABSTRACTWorldwide, measles remains a major cause of disease and death; the highest incidence is in the World Health Organization African Region (AFR). In 2011, the 46 AFR member states established a goal of regional measles elimination by 2020; this report describes progress during 2017-2021. Regional coverage with a first dose of measles-containing vaccine (MCV) decreased from 70% in 2017 to 68% in 2021, and the number of countries with ≥95% coverage decreased from six (13%) to two (4%). The number of countries providing a second MCV dose ...
Source: MMWR Morb Mortal Wkl... - September 7, 2023 Category: Epidemiology Authors: Balcha G Masresha Cynthia Hatcher Emmaculate Lebo Patricia Tanifum Ado M Bwaka Anna A Minta Sebastien Antoni Gavin B Grant Robert T Perry Patrick O'Connor Source Type: research
Retinal vein occlusion following BNT162b2 (Pfizer-BioNTech) COVID-19 vaccination
Singapore Med J. 2023 Aug 22. doi: 10.4103/singaporemedj.SMJ-2021-430. Online ahead of print.NO ABSTRACTPMID:37675679 | DOI:10.4103/singaporemedj.SMJ-2021-430
Source: Singapore Medical Journal - September 7, 2023 Category: General Medicine Authors: Duoduo Wu Blanche Xiao Hong Lim Dawn Ka-Ann Lim Gopal Lingam Chris Hong Long Lim Source Type: research
