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Total 19251 results found since Jan 2013.

Improving prognosis and assessing adjuvant chemotherapy benefit in locally advanced rectal cancer with deep learning for MRI: a retrospective, multi-cohort study
CONCLUSION: The MuST model accurately and non-invasively predicted OS, DM, and LR. A specific and direct tool linking chemotherapy decisions and benefit quantification has also been provided.PMID:37660753 | DOI:10.1016/j.radonc.2023.109899
Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - September 3, 2023 Category: Radiology Authors: Song Zhang Guoxiang Cai Peiyi Xie Caixia Sun Bao Li Weixing Dai Xiangyu Liu Qi Qiu Yang Du Zhenhui Li Zhenyu Liu Jie Tian Source Type: research

Effects of ammonia nitrogen and organic carbon availability on microbial community structure and ecological interactions in a full-scale partial nitritation and anammox (PN/A) system
In this study, a full-scale plug-flow partial nitritation/anammox (PN/A) system was used to investigate variations in the microbial community structure in both immobilized carriers and flocs, as well as a gradual decrease in nutrient availability from upstream to downstream. We found that reduced ammonia nitrogen (from 150.4 to 30.6 mg/L) and organic carbon (from 415.7 to 342.8 mg/L) availability significantly lowered microbial diversity and altered microbial communities in biofilms other than flocs from upstream to downstream. The abundance of all anammox bacteria increased by 1.97 times, from 3.25 × 1010 to 6.40 × 1010...
Source: Cell Research - September 2, 2023 Category: Cytology Authors: Lijun Yang Hong Yao Fangxu Jia Baohong Han Yao Chen Jie Jiang Tao Liu Jianhua Guo Source Type: research

Dermatobacter hominis gen. nov., sp. nov., a new member of the family Iamiaceae, revealed the potential utilisation of skin-derived metabolites
Antonie Van Leeuwenhoek. 2023 Sep 2. doi: 10.1007/s10482-023-01873-6. Online ahead of print.ABSTRACTA non-motile, novel actinobacterial strain, Kera-3T, which is a gram-positive, aerobic, rod-shaped bacterium, was isolated from human keratinocytes on 1/10 diluted R2A agar. Whole-cell hydrolysis of amino acids revealed the presence of meso-DAP, alanine, and glutamic acid. The predominant menaquinone was MK-9 (H8), whereas the primary fatty acids were C16:0 and C18:1 ω9c. The major phospholipids included diphosphatidylglycerol and aminophospholipids, along with an unidentified phosphoglycolipid and an aminophosphoglycolipid...
Source: Antonie van Leeuwenhoek - September 2, 2023 Category: Microbiology Authors: HyungWoo Jo Chaeyun Baek Young Mok Heo Hye-Been Kim Haeun Lee Seunghyun Kang Seyoung Mun Yunseok Oh Doyeong Ko Kyudong Han Ra úl Riesco Martha E Trujillo Dong-Geol Lee Source Type: research

Associations of Dietary Sugar Types with Coronary Heart Disease Risk: A Prospective Cohort Study
CONCLUSIONS: Intakes of TGE, total sugar, added sugar, and fructose from added sugar and juice were associated with higher CHD risk, but TFE and fructose from fruits and vegetables were not.PMID:37659725 | DOI:10.1016/j.ajcnut.2023.08.019
Source: Am J Clin Nutr - September 2, 2023 Category: Nutrition Authors: Kristine K Dennis Fenglei Wang Yanping Li JoAnn E Manson Eric B Rimm Frank B Hu Walter C Willett Meir J Stampfer Dong D Wang Source Type: research

Dermatobacter hominis gen. nov., sp. nov., a new member of the family Iamiaceae, revealed the potential utilisation of skin-derived metabolites
Antonie Van Leeuwenhoek. 2023 Sep 2. doi: 10.1007/s10482-023-01873-6. Online ahead of print.ABSTRACTA non-motile, novel actinobacterial strain, Kera-3T, which is a gram-positive, aerobic, rod-shaped bacterium, was isolated from human keratinocytes on 1/10 diluted R2A agar. Whole-cell hydrolysis of amino acids revealed the presence of meso-DAP, alanine, and glutamic acid. The predominant menaquinone was MK-9 (H8), whereas the primary fatty acids were C16:0 and C18:1 ω9c. The major phospholipids included diphosphatidylglycerol and aminophospholipids, along with an unidentified phosphoglycolipid and an aminophosphoglycolipid...
Source: Antonie van Leeuwenhoek - September 2, 2023 Category: Microbiology Authors: HyungWoo Jo Chaeyun Baek Young Mok Heo Hye-Been Kim Haeun Lee Seunghyun Kang Seyoung Mun Yunseok Oh Doyeong Ko Kyudong Han Ra úl Riesco Martha E Trujillo Dong-Geol Lee Source Type: research

Ketoprofen exposure perturbs nitrogen assimilation and ATP synthesis in rice roots: An integrated metabolome and microbiome analysis
Environ Pollut. 2023 Aug 31;336:122485. doi: 10.1016/j.envpol.2023.122485. Online ahead of print.ABSTRACTKetoprofen, a commonly used non-steroidal anti-inflammatory drug (NSAID), can enter farmland environments via sewage irrigation and manure application and is toxic to plants. However, there have been relatively few studies on the association of ketoprofen with nitrogen (N) assimilation and metabolic responses in plants. Accordingly, the goal of this study was to investigate the effects of ketoprofen on ATP synthesis and N assimilation in rice roots. The results showed that with increasing ketoprofen concentration, root ...
Source: Environmental Pollution - September 2, 2023 Category: Environmental Health Authors: Huan Wang Zhiheng Li Luoqin Shen Ping Zhang Yanyao Lin Xinting Huang Shaoting Du Huijun Liu Source Type: research

Associations of Dietary Sugar Types with Coronary Heart Disease Risk: A Prospective Cohort Study
CONCLUSIONS: Intakes of TGE, total sugar, added sugar, and fructose from added sugar and juice were associated with higher CHD risk, but TFE and fructose from fruits and vegetables were not.PMID:37659725 | DOI:10.1016/j.ajcnut.2023.08.019
Source: The American Journal of Clinical Nutrition - September 2, 2023 Category: Nutrition Authors: Kristine K Dennis Fenglei Wang Yanping Li JoAnn E Manson Eric B Rimm Frank B Hu Walter C Willett Meir J Stampfer Dong D Wang Source Type: research

Dermatobacter hominis gen. nov., sp. nov., a new member of the family Iamiaceae, revealed the potential utilisation of skin-derived metabolites
Antonie Van Leeuwenhoek. 2023 Sep 2. doi: 10.1007/s10482-023-01873-6. Online ahead of print.ABSTRACTA non-motile, novel actinobacterial strain, Kera-3T, which is a gram-positive, aerobic, rod-shaped bacterium, was isolated from human keratinocytes on 1/10 diluted R2A agar. Whole-cell hydrolysis of amino acids revealed the presence of meso-DAP, alanine, and glutamic acid. The predominant menaquinone was MK-9 (H8), whereas the primary fatty acids were C16:0 and C18:1 ω9c. The major phospholipids included diphosphatidylglycerol and aminophospholipids, along with an unidentified phosphoglycolipid and an aminophosphoglycolipid...
Source: Antonie van Leeuwenhoek - September 2, 2023 Category: Microbiology Authors: HyungWoo Jo Chaeyun Baek Young Mok Heo Hye-Been Kim Haeun Lee Seunghyun Kang Seyoung Mun Yunseok Oh Doyeong Ko Kyudong Han Ra úl Riesco Martha E Trujillo Dong-Geol Lee Source Type: research

Ketoprofen exposure perturbs nitrogen assimilation and ATP synthesis in rice roots: An integrated metabolome and microbiome analysis
Environ Pollut. 2023 Aug 31:122485. doi: 10.1016/j.envpol.2023.122485. Online ahead of print.ABSTRACTKetoprofen, a commonly used non-steroidal anti-inflammatory drug (NSAID), can enter farmland environments via sewage irrigation and manure application and is toxic to plants. However, there have been relatively few studies on the association of ketoprofen with nitrogen (N) assimilation and metabolic responses in plants. Accordingly, the goal of this study was to investigate the effects of ketoprofen on ATP synthesis and N assimilation in rice roots. The results showed that with increasing ketoprofen concentration, root vita...
Source: Environmental Pollution - September 2, 2023 Category: Environmental Health Authors: Huan Wang Zhiheng Li Luoqin Shen Ping Zhang Yanyao Lin Xinting Huang Shaoting Du Huijun Liu Source Type: research

Dermatobacter hominis gen. nov., sp. nov., a new member of the family Iamiaceae, revealed the potential utilisation of skin-derived metabolites
Antonie Van Leeuwenhoek. 2023 Sep 2. doi: 10.1007/s10482-023-01873-6. Online ahead of print.ABSTRACTA non-motile, novel actinobacterial strain, Kera-3T, which is a gram-positive, aerobic, rod-shaped bacterium, was isolated from human keratinocytes on 1/10 diluted R2A agar. Whole-cell hydrolysis of amino acids revealed the presence of meso-DAP, alanine, and glutamic acid. The predominant menaquinone was MK-9 (H8), whereas the primary fatty acids were C16:0 and C18:1 ω9c. The major phospholipids included diphosphatidylglycerol and aminophospholipids, along with an unidentified phosphoglycolipid and an aminophosphoglycolipid...
Source: Antonie van Leeuwenhoek - September 2, 2023 Category: Microbiology Authors: HyungWoo Jo Chaeyun Baek Young Mok Heo Hye-Been Kim Haeun Lee Seunghyun Kang Seyoung Mun Yunseok Oh Doyeong Ko Kyudong Han Ra úl Riesco Martha E Trujillo Dong-Geol Lee Source Type: research

Arachidonic acid metabolism CYP450 pathway is deregulated in hepatocellular carcinoma and associated with microvascular invasion
In this study, we investigated the expression of key genes involved in the arachidonic acid metabolism pathway in HCC using a combination of bioinformatics, proteomics and immunohistochemistry analyses. Through a comprehensive analysis of publicly available datasets, clinical HCC tissues, and tissue microarrays, we compared the expression of hepatic arachidonic acid metabolic genes. We observed significant downregulation of cytochrome P450 (CYP450) pathway genes at both the messenger RNA and protein levels in HCC tissues compared to normal liver tissues. Furthermore, we observed a strong correlation between the deregulatio...
Source: Cell Biology International - September 1, 2023 Category: Cytology Authors: Kai Wang Ji-Hua Shi Jie Gao Yaohui Sun Zhihui Wang Xiaoyi Shi Wenzhi Guo Yang Jin Shuijun Zhang Source Type: research