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Total 425 results found since Jan 2013.

Artificial intelligence in breast imaging: potentials and challenges
Phys Med Biol. 2023 Sep 18. doi: 10.1088/1361-6560/acfade. Online ahead of print.ABSTRACTBreast cancer, which is the most common type of malignant tumor among humans, is a leading cause of death in females. Standard treatment strategies, including neoadjuvant chemotherapy, surgery, postoperative chemotherapy, targeted therapy, endocrine therapy, and radiotherapy, are tailored for individual patients. Such personalized therapies have tremendously reduced the threat of breast cancer in females. Furthermore, early imaging screening plays an important role in reducing the treatment cycle and improving breast cancer prognosis. ...
Source: Physics in Medicine and Biology - September 18, 2023 Category: Physics Authors: Jiawei Li Danli Sheng Jiangang Chen Chao You Shuai Liu Huixiong Xu Cai Chang Source Type: research

Presentation of Gastrointestinal Stromal Tumor, Pancreatic Adenocarcinoma, and Gastric Adenocarcinoma in a Woman With No Identifiable Genetic Abnormalities
This report details the first known case of co-occurrence of gastrointestinal stromal tumor (GIST), pancreatic adenocarcinoma, and gastric adenocarcinoma in an individual with no identifiable genetic abnormalities. The patient is a 57-year-old female who presented with abdominal pain. CT scan demonstrated a pancreatic mass, and endoscopic ultrasound demonstrated an additional gastric mass. Biopsy of both masses demonstrated adenocarcinoma; however, the masses were found to have different origins. The patient underwent neoadjuvant chemotherapy with excellent response. She then underwent surgical intervention, which demonstr...
Source: The American Surgeon - September 12, 2023 Category: Surgery Authors: Catherine Read Marybeth Hughes Omar Itani Source Type: research

Prediction of Tumor PD-L1 Expression in Resectable Non-Small Cell Lung Cancer by Machine Learning Models Based on Clinical and Radiological Features: Performance Comparison With Preoperative Biopsy
CONCLUSIONS: Our machine learning could be an adjunctive tool in estimating PD-L1 expression prior to neoadjuvant treatment, particularly when PD-L1 is indeterminable with biopsy.PMID:37673781 | DOI:10.1016/j.cllc.2023.08.010
Source: Clinical Lung Cancer - September 6, 2023 Category: Cancer & Oncology Authors: Kohei Hashimoto Yu Murakami Kenshiro Omura Hikaru Takahashi Ryoko Suzuki Yasuo Yoshioka Masahiko Oguchi Junji Ichinose Yosuke Matsuura Masayuki Nakao Sakae Okumura Hironori Ninomiya Makoto Nishio Mingyon Mun Source Type: research

Clinical implications of dose to functional lung volumes in the trimodality treatment of esophageal cancer
CONCLUSION: Small ALV and increasing FLV exposed to intermediate (10 to 20 Gy) dose are associated to postoperative pulmonary complications. Changes of DLCO occur during nCRT but do not seem to be related to radiation dose to ALV or FLV. This information could attribute towards toxicity risk prediction and reduction strategies for EC.PMID:37643135 | DOI:10.1080/0284186X.2023.2251091
Source: Acta Oncologica - August 29, 2023 Category: Cancer & Oncology Authors: Pieter Populaire Gilles Defraene Philippe Nafteux Lieven Depypere Johnny Moons Sofie Isebaert Karin Haustermans Source Type: research

Impact of supradiaphragmatic lymphadenectomy on the survival of patients in stage IVB ovarian cancer with thoracic lymph node metastasis
ConclusionSupradiaphragmatic lymphadenectomy during PDS may improve survival in patients diagnosed with stage IVB ovarian cancer manifesting thoracic LNM. Further, suboptimal debulking surgery in the abdominal area may be associated with poor OS after IDS/NAC.Trial registrationClinicalTrials.gov (NCT05005650; https://clinicaltrials.gov/ct2/show/NCT05005650; first registration, 13/08/2021).Research Registry (Research Registry UIN, researchregistry7366; https://www.researchregistry.com/browse-the-registry#home/?view_2_search=researchregistry7366&view_2_page=1).
Source: Frontiers in Oncology - August 10, 2023 Category: Cancer & Oncology Source Type: research

Changes in Sarcopenia Status Predict Survival Among Patients with Resectable Esophageal Cancer
CONCLUSIONS: Patients who develop sarcopenia as a consequence of skeletal muscle wasting during neoadjuvant therapy are at risk for worse DFS and OS. Patients who have a net loss of muscle over time may be at high risk for early disease recurrence.PMID:37466867 | DOI:10.1245/s10434-023-13840-6
Source: Ann Oncol - July 19, 2023 Category: Cancer & Oncology Authors: Uzair M Jogiat Vickie Baracos Simon R Turner Dean Eurich Heather Filafilo Armin Rouhi Alexandre B édard Eric L R B édard Source Type: research

Epstein-Barr virus (EBV) induced pneumonitis in a patient with breast cancer receiving neoadjuvant chemotherapy: A case report
CONCLUSIONS: This case highlights the combined application of mNGS and traditional tests in the clinical diagnosis of invasive pulmonary infection. In the meanwhile, clinicians should be aware neoadjuvant chemotherapy for breast cancer carries a risk of EBV induced pneumonitis, so that EBV induced pneumonitis could be considered in differential diagnosis while similar patients present, to orchestrate improvements in diagnosis, treatment, and prognosis.PMID:37448884 | PMC:PMC10336251 | DOI:10.1016/j.rmcr.2023.101849
Source: Respiratory Care - July 14, 2023 Category: Respiratory Medicine Authors: Huibin Liao Miaojuan Zhu Zhenshun Cheng Source Type: research

Risk Factors for the Development of Early Recurrence in Patients with Primary Retroperitoneal Sarcoma
CONCLUSION: Early recurrence is associated with a poor prognosis, and a high tumor grade is an independent predictor for the development of EREC. Patients with EREC may benefit the most from new therapeutic options such as neoadjuvant chemotherapy.PMID:37423926 | DOI:10.1245/s10434-023-13754-3
Source: Ann Oncol - July 9, 2023 Category: Cancer & Oncology Authors: Fabio Tirotta Michael G Fadel Marco Baia Alessandro Parente Valentina Messina Paul Bassett L Max Almond Samuel J Ford Anant Desai Winan J van Houdt Dirk C Strauss Source Type: research

Utility of < sup > 18 < /sup > F-FDG uptake in predicting major pathological response to neoadjuvant immunotherapy in patients with resectable non ‑small cell lung cancer
CONCLUSION: 18F-FDG uptake can predict MPR in NSCLC patients with neoadjuvant immunotherapy.PMID:37421908 | DOI:10.1016/j.tranon.2023.101725
Source: Translational Oncology - July 8, 2023 Category: Cancer & Oncology Authors: Xiaowei Chen Guangyu Bai Ruochuan Zang Peng Song Fenglong Bie Qilin Huai Yuan Li Yang Liu Bolun Zhou Yifan Bie Zhenlin Yang Shugeng Gao Source Type: research