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Vaccination: Ebola Vaccine

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Total 607 results found since Jan 2013.

Viral vectors engineered for gene therapy
Int Rev Cell Mol Biol. 2023;379:1-41. doi: 10.1016/bs.ircmb.2023.05.005. Epub 2023 Jul 1.ABSTRACTGene therapy has seen major progress in recent years. Viral vectors have made a significant contribution through efficient engineering for improved delivery and safety. A large variety of indications such as cancer, cardiovascular, metabolic, hematological, neurological, muscular, ophthalmological, infectious diseases, and immunodeficiency have been targeted. Viral vectors based on adenoviruses, adeno-associated viruses, herpes simplex viruses, retroviruses including lentiviruses, alphaviruses, flaviviruses, measles viruses, rh...
Source: International Review of Cell and Molecular Biology - August 4, 2023 Category: Cytology Authors: Kenneth Lundstrom Source Type: research

The Utilization and Development of Viral Vectors in Vaccines as a Prophylactic Treatment Against Ebola Virus as an Emerging and Zoonotic Infectious Disease
Mini Rev Med Chem. 2023 Jul 25. doi: 10.2174/1389557523666230725115324. Online ahead of print.ABSTRACTAlongside the prescription of commonly used antivirals, such as acyclovir, remdesivir, oseltamivir, and ciprofloxacin, the most efficient way to prevent or treat communicable diseases is by vaccination. Vaccines have been the most efficient way to prevent or treat highly transmissible infectious agents, such as Ebola, Anthrax, and Dengue Fever. Most epidemics of these highly transmissible infectious agents occur in places, such as South America, Central America, Tropical Asia, and Africa, where the availability of resource...
Source: Mini Reviews in Medicinal Chemistry - July 25, 2023 Category: Chemistry Authors: Anthony Garcia Oliver Grundmann Source Type: research

Exclusion of pregnant people from emergency vaccine clinical trials: A systematic review of clinical trial protocols and reporting from 2009 to 2019
CONCLUSION: Pregnant people are underrepresented in vaccine clinical trials conducted during outbreaks, resulting in underreporting of pregnancy-related outcomes and a lack of protection for pregnant people and neonates from infectious diseases.PMID:37442686 | DOI:10.1016/j.vaccine.2023.06.073
Source: Vaccine - July 13, 2023 Category: Allergy & Immunology Authors: Jamie Minchin Gavin H Harris Sasha Baumann Emily R Smith Source Type: research

Biomaterial-based delivery platforms for transdermal immunotherapy
Biomed Pharmacother. 2023 Jun 27;165:115048. doi: 10.1016/j.biopha.2023.115048. Online ahead of print.ABSTRACTNowadays, immunotherapy is one of the most essential treatments for various diseases and a broad spectrum of disorders are assumed to be treated by altering the function of the immune system. For this reason, immunotherapy has attracted a great deal of attention and numerous studies on different approaches for immunotherapies have been investigated, using multiple biomaterials and carriers, from nanoparticles (NPs) to microneedles (MNs). In this review, the immunotherapy strategies, biomaterials, devices, and disea...
Source: Biomedicine and pharmacotherapy = Biomedecine and pharmacotherapie - June 29, 2023 Category: Drugs & Pharmacology Authors: Mohammad Dahri Nima Beheshtizadeh Nasrin Seyedpour Amin Nakhostin-Ansari Faezeh Aghajani Simin Seyedpour Moein Masjedi Fatemeh Farjadian Reza Maleki Khosro Adibkia Source Type: research

Na ïve antibody library derived monoclonal antibody against VP35 of Ebola virus
In conclusion, the information obtained from the 3 isolated mAbs could be potentially useful in the quest to improve VP35 targeting for therapeutic development in the future.PMID:37379953 | DOI:10.1016/j.ijbiomac.2023.125571
Source: International Journal of Biological Macromolecules - June 28, 2023 Category: Biochemistry Authors: Jing Yi Lai Angela Corona Chong Lee Ng Enzo Tramontano Yee Siew Choong Theam Soon Lim Source Type: research

Sudan virus disease - A quick review
J Formos Med Assoc. 2023 Jun 22:S0929-6646(23)00229-2. doi: 10.1016/j.jfma.2023.06.001. Online ahead of print.ABSTRACTThe recent Sudan virus disease (SVD) outbreak in Uganda is a reminder of threat from Filovirus diseases. Unlike Ebola virus disease, no effective antiviral and vaccine is available for SVD. The outbreak was declared over after 115 days, with 142 confirmed cases and case fatality rate of 39%, before any dose of candidate vaccine could be used on contacts. We provide a quick review of up-to-date information on the Uganda outbreak, summary of previous outbreaks, and detail the existing SVD treatment and vaccin...
Source: J Formos Med Assoc - June 24, 2023 Category: General Medicine Authors: Tsung-Pei Tsou Source Type: research

Effects of public health emergencies of international concern on disease control: a systematic review
CONCLUSIONS: Socioeconomic inequity is a determinant of the effects of public health emergencies of international concern within affected populations. The diversion of resources and attention from health authorities disproportionately affects vulnerable populations and can lead, over time, to a weakening of health systems. The analysis of the effects of public health emergencies is important for the development of new protocols that can better respond to future crises.PMID:37089787 | PMC:PMC10120386 | DOI:10.26633/RPSP.2023.74
Source: Pan American Journal of Public Health - April 24, 2023 Category: International Medicine & Public Health Authors: Giovanna Rotondo de Ara újo Pedro A S V de Castro Isabela R Ávila Juliana Maria T Bezerra David S Barbosa Source Type: research