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Total 141452 results found since Jan 2013.

Prevalence, risk factors, clinical course, and outcome of acute kidney injury in Chinese intensive care units: a prospective cohort study.
CONCLUSIONS: The prevalence of AKI was high among critically ill patients in Chinese ICUs. In comparison with non-AKI patients, patients with RIFLE class R or class I on ICU admission were more susceptibility to progression to class I or class F. The RIFLE criteria were robust and correlated well with clinical deterioration and mortality. PMID: 24286398 [PubMed - in process]
Source: Chinese Medical Journal - November 30, 2013 Category: Journals (General) Authors: Wen Y, Jiang L, Xu Y, Qian CY, Li SS, Qin TH, Chen EZ, Lin JD, Ai Y, Wu DW, Wang YS, Sun RH, Hu ZJ, Cao XY, Zhou FC, He ZY, Zhou LH, An YZ, Kang Y, Ma XC, Yu XY, Zhao MY, Xi XM, DU B, China Critical Care Clinical Trial Group (CCCCTG) Tags: Chin Med J (Engl) Source Type: research

Sovaldi - a "Revolution" in Clinical Care, or in Marketing and Public Relations?
DiscussionWashington Post/ Kaiser Health NewsOn May 12, 2014, in an article on the dilemma the drug's US price of $1000/ pill presents to Medicare, Richard Knox wrote this about a patient with the infection:Previous drug treatments didn't clear the virus from Bianco's system. But it's almost certain that potent new drugs for hep-C could cure him. In other words, the article asserted that Sovaldi and similar drugs cure nearly everyone with hepatitis C, even those not cured by previous treatment.  ReutersOn May 20, 2014, in an article about how US health insurers are balking at the price of Sovaldi, was this statement b...
Source: Health Care Renewal - May 28, 2014 Category: Health Management Tags: evidence-based medicine Gilead health care prices manipulating clinical research Sovaldi You heard it here first Source Type: blogs

A randomized controlled pilot trial to improve advance care planning for LVAD patients and their surrogates
Conclusions SPIRIT-HF is feasible and acceptable. Results will inform future trials.
Source: Heart and Lung: The Journal of Acute and Critical Care - March 3, 2016 Category: Respiratory Medicine Source Type: research

Procalcitonin accurately predicts lung transplant adults with low risk of pulmonary graft dysfunction and intensive care mortality
Conclusions A breakpoint of PCT<2ng/mL within 24h has a high predictive value to exclude grade 3 PGD at 72h and for ICU survival. Moreover, both PCT and IL-10 within 48h were associated with significantly better graft function one year after surgery.
Source: Journal of Critical Care - November 6, 2017 Category: Gastroenterology Source Type: research

Lung Transplant for the Critical Care Nurse
This article reviews routine postsurgical intensive care unit management, along with management of complications such as acute kidney injury, atrial arrhythmias, deep vein thrombosis, primary graft dysfunction, hyperammonemia syndrome, and thrombocytopenia. Finally, management of long-term issues, including diabetes mellitus, hypertension, and bronchial stenosis, is discussed.
Source: Critical Care Nursing Clinics of North America - June 23, 2019 Category: Nursing Authors: Kevin C. Carney, Tanya Bronzell-Wynder, Karen Gronek Source Type: research

Anaesthesia and intensive care for adult liver transplantation
Publication date: Available online 4 June 2015 Source:Anaesthesia & Intensive Care Medicine Author(s): Craig Beattie , Michael A. Gillies This review describes the preoperative assessment and listing of the patient for liver transplantation and some of the specific perioperative challenges this group of patients present to the anaesthetist. The principles of the early postoperative management in the intensive care unit are discussed as well as some of the signs of early graft dysfunction. Increasingly unwell patients receiving grafts that may come from more marginal donors present significant challenges to the tr...
Source: Anaesthesia and intensive care medicine - June 5, 2015 Category: Anesthesiology Source Type: research

Extracorporeal Membrane Oxygenation Candidacy in Pediatric Patients Treated With Hematopoietic Stem Cell Transplant and Chimeric Antigen Receptor T-Cell Therapy: An International Survey
ConclusionsECMO use for pediatric patients treated with HCT and CAR-T therapy is generally acceptable amongst physicians. However, there are differences in the evaluation and decision-making regarding ECMO candidacy amongst providers across medical specialties and institutions. Therefore, multidisciplinary collaboration is an essential component in establishing practice guidelines and advancing ECMO outcomes for these patients.
Source: Frontiers in Oncology - December 22, 2021 Category: Cancer & Oncology Source Type: research

Research and Reviews in the Fastlane 177
This study has some frustrating findings: they looked at 318 patients who got a CTPA within 2 weeks of a negative CTPA and found a 5% positive rate. Is CTPA like a stress test, where we just can’t predict plaque rupture? Are people who get CTPAs people who other docs are also worried about PE? Or are we just ordering too many CTPAs? How many of these were false postives or negatives? Sadly, as with most clinical research on pulmonary embolism, I am let with more questions than answers (but we probably order too many CTPAs). Recommended by: Seth Trueger Pediatrics Luck RP, et al. Cosmetic outcomes of absorbable ver...
Source: Life in the Fast Lane - March 30, 2017 Category: Emergency Medicine Authors: Nudrat Rashid Tags: Clinical Case Education Emergency Medicine Infectious Disease Intensive Care Pediatrics R&R in the FASTLANE Radiology Respiratory Resuscitation critical care research and reviews Source Type: blogs

Advanced Clinical Topics in Pediatric Palliative Care (P06)
This full-day workshop will focus exclusively on advanced medical topics that profoundly influence the practice of pediatric palliative care. Ten pediatric faculty representing seven programs across the country will serve as session moderators and small-group leaders, while the core content will be delivered by national experts in a variety of disciplines, including cardiology, transplant medicine, critical care, pain management, and psychopharmacology, who were invited by the core pediatric palliative care faculty.
Source: Journal of Pain and Symptom Management - January 25, 2015 Category: Palliative Care Authors: Jennifer Minarcik Hwang, Tammy Kang, Elissa Miller, Sarah Friebert, Gina Santucci, Wynne Morrison, Jeffrey Klick, Richard Goldstein, Kathie Kobler, Lindsay Burns Ragsdale, Joseph Rossano, Roxanne Kirsch, Samuel B. Goldfarb, Kathryn Dodds, Jeremy Hirst, Jo Source Type: research

3-Dimensional nature-based therapeutics in pediatric patients with total pancreatectomy and islet auto-transplant.
CONCLUSIONS: In this proof of concept study, children in a critical care setting were able to utilize VR devices for NBT after extensive surgical procedures. Initial quantitative scoring systems suggest overall improvement in symptom management, and reactions by both patients and their parents were overall positive. PMID: 31987236 [PubMed - in process]
Source: Complementary Therapies in Medicine - December 31, 2019 Category: Complementary Medicine Authors: Kucher N, Larson JM, Fischer G, Mertaugh M, Peterson L, Gershan LA Tags: Complement Ther Med Source Type: research

ASBH Annual Meeting – Lots of EOL Sessions
The ASBH Annual Meeting is October 21-25, 2015 in Houston.   If you are not already planning to go, check out this huge list of sessions on EOL.  And this is just a subset of those on the program. Brain Death Can the Brain Dead be Harmed or Wronged? On the Moral Status of Brain De… Religious Exemptions and the Duality of Death Are Brain Dead Human Beings Really Dead? Done to Death: Yet Another Argument About Defining Death—Where Miller & … Futility Non-beneficial Treatment Cases: A Policy Approach? Preventive Ethics in an ICU Setting: A Pilot Study Legal Update 2015: Top...
Source: blog.bioethics.net - August 9, 2015 Category: Medical Ethics Authors: Thaddeus Mason Pope Tags: Health Care medical futility blog syndicated Source Type: blogs

‘Sophie’s Choice’ in the time of coronavirus: Deciding who gets the ventilator
Three otherwise healthy patients go to the emergency department with severe acute respiratory failure. Only one ventilator, required to sustain life until the worst of the coronavirus infection has passed, is available. Who gets the vent? That’s what “A Framework for Rationing Ventilators and Critical Care Beds During the COVID-19 Pandemic,” a Viewpoint just published in the Journal of the American Medical Association (JAMA), addresses. Douglas White, MD, MAS, Endowed Chair for Ethics in Critical Care Medicine at the University of Pittsburgh School of Medicine ...
Source: blog.bioethics.net - April 6, 2020 Category: Medical Ethics Authors: Bioethics Today Tags: Health Care Author: Lewis syndicated Source Type: blogs

Inconsistencies in care of the pediatric hematopoietic stem cell transplant recipient with respiratory failure: Opportunity for standardization and improved outcome
Abstract There is variability in critical care outcome of the HSCT recipient. One potential reason may be due to the inconsistent ventilation approaches. To quantitate this variability, we conducted a survey to assess self‐reported use of ventilation and adjunctive strategies for the HSCT recipient. Electronic survey, open from June 2012 through January 201, distributed through the Pediatric Acute Lung Injury and Sepsis Investigators network electronic mailing list. Ninety‐four individual responses were from 36 different institutions. The majority indicated that HSCT recipients requiring critical care were admitted to ...
Source: Pediatric Transplantation - January 11, 2014 Category: Transplant Surgery Authors: Courtney M. Rowan, Mara E. Nitu, Mark R Rigby Tags: Original Article Source Type: research

Experience with Mechanical Circulatory Support for Medically Intractable Low Cardiac Output in a Pediatric Intensive Care Unit.
CONCLUSION: Mechanical circulatory support has played a critical role and has had a dramatic effect on survival in patients with medically intractable heart failure, particularly in recent years. Meticulous monitoring of acid-base status, laboratory findings, and early and liberal applications are recommended to improve outcomes without critical complication rates, particularly in neonates with single ventricle physiology. PMID: 28765741 [PubMed]
Source: Korean Circulation Journal - August 3, 2017 Category: Cardiology Tags: Korean Circ J Source Type: research

How Tech Can Optimize Protocol-Driven Care For Children With Medical Complexity
The following is a guest article by Tammi Jantzen, Co-Founder & CFO at Astarte Medical Medical advances have led to improved survival for many previously life-threatening conditions of childhood, such as prematurity, congenital anomalies (like congenital heart defects), and congenital or acquired brain injury (like cerebral palsy). Technological advances such as ventilator support, feeding tubes and transplantation have successfully prolonged the lives of children with lung, gut, and other organ failure. This epidemiological shift has created a growing population of children with medical complexity (CMC)—children...
Source: EMR and HIPAA - April 7, 2023 Category: Information Technology Authors: Guest Author Tags: Communication and Patient Experience Health IT Company Healthcare IT Hospital - Health System Astarte Medical Children with Medical Complexity Chronic Health Condition CMC Congenital Diseases Digital Tools EMR Inappropriate Care Ne Source Type: blogs