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Nutrition: Vitamins

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Total 41192 results found since Jan 2013.

Fortification of condiments and seasonings with iron for preventing anaemia and improving health
CONCLUSIONS: We are uncertain whether consuming iron-fortified condiments/seasonings reduces anaemia, improves haemoglobin concentration, or improves ferritin concentration. It may reduce ID. Findings about ferritin should be interpreted with caution since its concentrations increase during inflammation. Consuming condiments/seasonings fortified with iron plus other micronutrients may reduce anaemia, and we are uncertain whether this will improve haemoglobin concentration or ferritin concentration. More studies are needed to determine the true effect of iron-fortified condiments/seasonings on preventing anaemia and improvi...
Source: Cochrane Database of Systematic Reviews - September 4, 2023 Category: General Medicine Authors: Chowdhury Sb Jalal Luz Maria De-Regil Vanessa Pike Prasanna Mithra Source Type: research

Attenuation of homeostatic sleep response and rest-activity circadian rhythm in vitamin D deficient mice
Chronobiol Int. 2023 Sep 4:1-14. doi: 10.1080/07420528.2023.2253299. Online ahead of print.ABSTRACTThe link between vitamin D deficiency (VDD) and sleep disturbances has long been suggested. However, the direct causality between VDD, sleep disturbances, and circadian rhythm remains unclear. We aimed to characterize sleep-wake behavior and circadian rhythms in an animal model of VDD. VDD was induced by feeding vitamin D-deficient chow, and we analyzed sleep and circadian rhythm parameters. During light period, VDD mice exhibited reduced wake with more frequent wake bouts and increased NREM sleep time. However, during dark p...
Source: Chronobiology International - September 4, 2023 Category: Biology Authors: Jieun Jung Jiseung Kang Tae Kim Source Type: research

Vitamin D status and supplementation before and after Bariatric Surgery: Recommendations based on a systematic review and meta-analysis
Rev Endocr Metab Disord. 2023 Sep 4. doi: 10.1007/s11154-023-09831-3. Online ahead of print.ABSTRACTBariatric surgery is associated with a postoperative reduction of 25(OH) vitamin D levels (25(OH)D) and with skeletal complications. Currently, guidelines for 25(OH)D assessment and vitamin D supplementation in bariatric patients, pre- and post-surgery, are still lacking. The aim of this work is to analyse systematically the published experience on 25(OH)D status and vitamin D supplementation, pre- and post-surgery, and to propose, on this basis, recommendations for management. Preoperatively, 18 studies including 2,869 pati...
Source: ENDOCR REV - September 4, 2023 Category: Endocrinology Authors: Andrea Giustina Luigi di Filippo Antonio Facciorusso Robert A Adler Neil Binkley Jens Bollerslev Roger Bouillon Felipe F Casanueva Giulia Martina Cavestro Marlene Chakhtoura Caterina Conte Lorenzo M Donini Peter R Ebeling Angelo Fassio Stefano Frara Claud Source Type: research

Fortification of condiments and seasonings with iron for preventing anaemia and improving health
CONCLUSIONS: We are uncertain whether consuming iron-fortified condiments/seasonings reduces anaemia, improves haemoglobin concentration, or improves ferritin concentration. It may reduce ID. Findings about ferritin should be interpreted with caution since its concentrations increase during inflammation. Consuming condiments/seasonings fortified with iron plus other micronutrients may reduce anaemia, and we are uncertain whether this will improve haemoglobin concentration or ferritin concentration. More studies are needed to determine the true effect of iron-fortified condiments/seasonings on preventing anaemia and improvi...
Source: Cochrane Database of Systematic Reviews - September 4, 2023 Category: General Medicine Authors: Chowdhury Sb Jalal Luz Maria De-Regil Vanessa Pike Prasanna Mithra Source Type: research

Vitamin D status and supplementation before and after Bariatric Surgery: Recommendations based on a systematic review and meta-analysis
Rev Endocr Metab Disord. 2023 Sep 4. doi: 10.1007/s11154-023-09831-3. Online ahead of print.ABSTRACTBariatric surgery is associated with a postoperative reduction of 25(OH) vitamin D levels (25(OH)D) and with skeletal complications. Currently, guidelines for 25(OH)D assessment and vitamin D supplementation in bariatric patients, pre- and post-surgery, are still lacking. The aim of this work is to analyse systematically the published experience on 25(OH)D status and vitamin D supplementation, pre- and post-surgery, and to propose, on this basis, recommendations for management. Preoperatively, 18 studies including 2,869 pati...
Source: ENDOCR REV - September 4, 2023 Category: Endocrinology Authors: Andrea Giustina Luigi di Filippo Antonio Facciorusso Robert A Adler Neil Binkley Jens Bollerslev Roger Bouillon Felipe F Casanueva Giulia Martina Cavestro Marlene Chakhtoura Caterina Conte Lorenzo M Donini Peter R Ebeling Angelo Fassio Stefano Frara Claud Source Type: research

Malignant hypercalcemia revealing a diffuse large B ‐cell lymphoma in a patient with a previous diagnosis of chronic myelomonocytic leukemia: An uncommon hematological coexistence
Key Clinical MessageA 76-year-old patient previously admitted to the cardiology department for replacement of a right ventricular lead on a double-chamber pacemaker was admitted to the internal medicine department 15  days after for bronchopneumopathy. His past medical history was relevant for Type 2 diabetes mellitus, heart failure due to dilated hypokinetic heart disease, transcatheter aortic valve implantation (TAVI), and chronic myelomonocytic leukemia (CMML-0) diagnosed in 2021. Twenty-four hours after ad mission, the patient's general condition deteriorated abruptly, with the onset of drowsiness and psychomotor ret...
Source: Clinical Case Reports - September 4, 2023 Category: General Medicine Authors: Alpha Oumar Diallo, Amelie Marcou, J érémie Lespinasse, Zaida Cordoba‐Sosa, Emmanuel Andrès, Léa Docquier, Noel Lorenzo‐Villalba Tags: CASE REPORT Source Type: research

The magic of a methyl group: biochemistry at the service of medicine
Biochem Pharmacol. 2023 Sep 1:115786. doi: 10.1016/j.bcp.2023.115786. Online ahead of print.ABSTRACTA carbon-carbon linkage is created when a methyl group is implanted on dUMP, thus resulting in the formation of dTMP by thymidylate synthase. The methyl group is deleted by aromatase when androgens are converted to estrogens. The methyl group is rearranged with the help of vitamin B12 in the isomerization of methylmalonyl-CoA to succinyl-CoA. S-adenosylmethionine (SAM) serves as the universal methyl donor involved in the biosynthesis of adrenaline and creatine(phosphate). It also interferes with the 5'-mRNA capping and the d...
Source: Biochemical Pharmacology - September 3, 2023 Category: Drugs & Pharmacology Authors: Erik De Clercq Source Type: research

Prediction of major bleeding events in 1381 patients with essential thrombocythemia
Int J Hematol. 2023 Sep 3. doi: 10.1007/s12185-023-03650-7. Online ahead of print.ABSTRACTThe goal of therapy in essential thrombocythemia (ET) is reducing thrombotic risk. No algorithm to predict hemorrhage risk exists. The impact ofanti-platelet, cytoreductive and anticoagulation therapies on risk of major bleeding (MB) was evaluated. MB events were retrospectively analyzed in 1381 ET from 10 European centers. There were 0.286 MB events/person-year. Neither the International Thrombosis Prognostic Score for thrombosis in essential thrombocythemia (IPSET-t) nor the revised IPSET-t (r-IPSET-t) was predictive for hemorrhage-...
Source: International Journal of Hematology - September 3, 2023 Category: Hematology Authors: Ruth Stuckey Jean-Christophe Ianotto Marco Santoro Anna Czy ż Manuel M Perez Encinas Mar ía Teresa Gómez-Casares Maria Soledad Noya Pereira Anna Kulikowska de Na łęcz Aleksandra Go łos Krzysztof Lewandowski Łukasz Szukalski Jes ús M González-Mart Source Type: research

Periconceptional intakes of methyl donors and other micronutrients involved in one-carbon metabolism may further reduce the risk of neural tube defects in offspring: a United States population-based case-control study of women meeting the folic acid recommendations
CONCLUSIONS: Our findings support that NTD prevention, in the context of folic acid fortification, could be augmented with intakes of methyl donors and other micronutrients involved in folate metabolism.PMID:37661108 | DOI:10.1016/j.ajcnut.2023.05.034
Source: Am J Clin Nutr - September 3, 2023 Category: Nutrition Authors: Julie M Petersen Rashida S Smith-Webb Gary M Shaw Suzan L Carmichael Tania A Desrosiers Eirini Nestoridi Anne Marie Darling Samantha E Parker Maria D Politis Mahsa M Yazdy Martha M Werler National Birth Defects Prevention Study Source Type: research

Vitamin D supplementation for improving bone density in vitamin D-deficient children and adolescents: systematic review and individual participant data meta-analysis of randomized controlled trials
CONCLUSIONS: Clinically important benefits for bone density from 1-y vitamin D supplementation in healthy children and adolescents, regardless of baseline vitamin D status, are unlikely. However, our findings are mostly generalizable to White postpubertal girls and do not apply to those with baseline 25(OH)D outside the studied range or with symptomatic vitamin D deficiency (e.g., rickets). This study was preregistered at PROSPERO as CRD42017068772. https://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42017068772.PMID:37661104 | DOI:10.1016/j.ajcnut.2023.05.028
Source: Am J Clin Nutr - September 3, 2023 Category: Nutrition Authors: Feitong Wu Ghada El-Hajj Fuleihan Guoqi Cai Christel Lamberg-Allardt Heli T Viljakainen Maya Rahme Ida M Gr ønborg Rikke Andersen Anuradha Khadilkar Mughal M Zulf Christian M ølgaard Anni Larnkj ær Kun Zhu Richard D Riley Tania Winzenberg Source Type: research

Health Benefits of Vitamin D Supplementation: Time to Move the Spotlight Away from Bone Health in Vitamin D-replete Individuals?
Am J Clin Nutr. 2023 Sep;118(3):489-490. doi: 10.1016/j.ajcnut.2023.06.017. Epub 2023 Aug 8.NO ABSTRACTPMID:37661100 | DOI:10.1016/j.ajcnut.2023.06.017
Source: Am J Clin Nutr - September 3, 2023 Category: Nutrition Authors: Sue A Shapses Mona S Calvo Source Type: research

Periconceptional intakes of methyl donors and other micronutrients involved in one-carbon metabolism may further reduce the risk of neural tube defects in offspring: a United States population-based case-control study of women meeting the folic acid recommendations
CONCLUSIONS: Our findings support that NTD prevention, in the context of folic acid fortification, could be augmented with intakes of methyl donors and other micronutrients involved in folate metabolism.PMID:37661108 | DOI:10.1016/j.ajcnut.2023.05.034
Source: The American Journal of Clinical Nutrition - September 3, 2023 Category: Nutrition Authors: Julie M Petersen Rashida S Smith-Webb Gary M Shaw Suzan L Carmichael Tania A Desrosiers Eirini Nestoridi Anne Marie Darling Samantha E Parker Maria D Politis Mahsa M Yazdy Martha M Werler National Birth Defects Prevention Study Source Type: research

Vitamin D supplementation for improving bone density in vitamin D-deficient children and adolescents: systematic review and individual participant data meta-analysis of randomized controlled trials
CONCLUSIONS: Clinically important benefits for bone density from 1-y vitamin D supplementation in healthy children and adolescents, regardless of baseline vitamin D status, are unlikely. However, our findings are mostly generalizable to White postpubertal girls and do not apply to those with baseline 25(OH)D outside the studied range or with symptomatic vitamin D deficiency (e.g., rickets). This study was preregistered at PROSPERO as CRD42017068772. https://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42017068772.PMID:37661104 | DOI:10.1016/j.ajcnut.2023.05.028
Source: The American Journal of Clinical Nutrition - September 3, 2023 Category: Nutrition Authors: Feitong Wu Ghada El-Hajj Fuleihan Guoqi Cai Christel Lamberg-Allardt Heli T Viljakainen Maya Rahme Ida M Gr ønborg Rikke Andersen Anuradha Khadilkar Mughal M Zulf Christian M ølgaard Anni Larnkj ær Kun Zhu Richard D Riley Tania Winzenberg Source Type: research

Health Benefits of Vitamin D Supplementation: Time to Move the Spotlight Away from Bone Health in Vitamin D-replete Individuals?
Am J Clin Nutr. 2023 Sep;118(3):489-490. doi: 10.1016/j.ajcnut.2023.06.017. Epub 2023 Aug 8.NO ABSTRACTPMID:37661100 | DOI:10.1016/j.ajcnut.2023.06.017
Source: The American Journal of Clinical Nutrition - September 3, 2023 Category: Nutrition Authors: Sue A Shapses Mona S Calvo Source Type: research

Safety evaluation of rare ginsenosides of stems and leaves from American ginseng: 90-day exposure toxicity study combined with intestinal flora analysis and metabonomics in rats
Ecotoxicol Environ Saf. 2023 Sep 1;264:115429. doi: 10.1016/j.ecoenv.2023.115429. Online ahead of print.ABSTRACTRare ginsenosides have already been widely applied in many fields, including health food and bio-medicine. The human being can expose to rare ginsenosides directly or indirectly increasingly. However, there are few studies on the safety assessment of rare ginsenoside mixtures. In the present study, the sub-chronic toxicity of rare ginsenosides for 90 days on SD rats was performed by combining the intestinal flora analysis and urine metabonomics aiming to illustrate the safety of long-term consumption of rare gins...
Source: Ecotoxicology and Environmental Safety - September 3, 2023 Category: Environmental Health Authors: Yuqing Cao Feiyan Tao Yuan Yu Linmeng Song Ruoyu Zhang Jing Feng Qingfeng Zhai Peng Xue Source Type: research