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Total 24253 results found since Jan 2013.

Microplastics and phthalate esters release from teabags into tea drink: occurrence, human exposure, and health risks
Environ Sci Pollut Res Int. 2023 Sep 12. doi: 10.1007/s11356-023-29726-9. Online ahead of print.ABSTRACTTea, the most common infusion worldwide, is usually sold in teabags due to the ease of usage. The increase in the use of plastic materials in the food packaging industry has led to an increase in released contaminants, such as microplastics (MPs) and phthalates (PAEs), in various food products including teabags. In this research, the abundance and features of MPs as well as PAEs concentration were investigated in 45 teabag samples of different Persian and German brands. The abundance of MPs in the Persian and German teab...
Source: Environmental Science and Pollution Research International - September 11, 2023 Category: Environmental Health Authors: Fatemeh Sadat Kashfi Azam Mohammadi Farzaneh Rostami Arezou Savari Gabriel E De-la-Torre J örg Spitz Reza Saeedi Mohammadreza Kalantarhormozi Akram Farhadi Sina Dobaradaran Source Type: research

Molecular Mechanism of Qingzaojiufei Decoction in the Treatment of Pulmonary Fibrosis based on Network Pharmacology and Molecular Docking
CONCLUSION: This research shows the multiple active components and molecular mechanism of QD in the treatment of PF and offers resources and suggestions for future studies.PMID:37694785 | DOI:10.2174/1381612829666230911105931
Source: Current Pharmaceutical Design - September 11, 2023 Category: Drugs & Pharmacology Authors: Yilong Zhao Bohao Liu Yixing Li Chen Zhe Xingzhuo Zhu Runyi Tao Zhiyu Wang Hongyi Wang Yanpeng Zhang Shuguang Yan Qiuyu Gong Guangjian Zhang Source Type: research

Effects of Dichloromethane and N-Butanol Fractions of < em > Nigella sativa < /em > on ACHN and GP-293 Cell Line Morphology, Viability, and Apoptosis
CONCLUSION: Our findings demonstrated that these two fractions of N. sativa induce inhibitory effects on the ACHN cell line morphology and viability. These effects were lower than those induced by the total extract. In addition, the two fractions caused more marked effects in the renal cancer cell line compared with the GP-293 cell line.PMID:37694244 | PMC:PMC10492620 | DOI:10.4103/abr.abr_394_22
Source: Biomed Res - September 11, 2023 Category: Research Authors: Samira Shahraki Sara Hosseinian Elham Shahraki Mehdi Kheirandish Abolfazl Khajavirad Source Type: research

Idiopathic Mesenteric Phlebosclerosis Secondary to Chinese Herbal Medicine Intake in an Older Adult
Am J Trop Med Hyg. 2023 Sep 11:tpmd220772. doi: 10.4269/ajtmh.22-0772. Online ahead of print.NO ABSTRACTPMID:37696511 | DOI:10.4269/ajtmh.22-0772
Source: Am J Trop Med Hyg - September 11, 2023 Category: Infectious Diseases Authors: Akira Kawashima Akira Shimomura Takeshi Inagaki Source Type: research

Molecular Mechanism of Qingzaojiufei Decoction in the Treatment of Pulmonary Fibrosis based on Network Pharmacology and Molecular Docking
CONCLUSION: This research shows the multiple active components and molecular mechanism of QD in the treatment of PF and offers resources and suggestions for future studies.PMID:37694785 | DOI:10.2174/1381612829666230911105931
Source: Current Pharmaceutical Design - September 11, 2023 Category: Drugs & Pharmacology Authors: Yilong Zhao Bohao Liu Yixing Li Chen Zhe Xingzhuo Zhu Runyi Tao Zhiyu Wang Hongyi Wang Yanpeng Zhang Shuguang Yan Qiuyu Gong Guangjian Zhang Source Type: research

Idiopathic Mesenteric Phlebosclerosis Secondary to Chinese Herbal Medicine Intake in an Older Adult
Am J Trop Med Hyg. 2023 Sep 11:tpmd220772. doi: 10.4269/ajtmh.22-0772. Online ahead of print.NO ABSTRACTPMID:37696511 | DOI:10.4269/ajtmh.22-0772
Source: Am J Trop Med Hyg - September 11, 2023 Category: Infectious Diseases Authors: Akira Kawashima Akira Shimomura Takeshi Inagaki Source Type: research

Investigation on anti-diabetic efficacy of a Cucurbitaceae food plant from the North-East region of India: Exploring the molecular mechanism through modulation of oxidative stress and glycosylated hemoglobin (HbA1c)
CONCLUSION: Based on the current evaluation, it was found that EASH exhibited encouraging hypoglycemic effects in diabetic rats induced by a low dose of STZ and high-fat diet, which warrants further investigation.PMID:37691221 | DOI:10.2174/1871530323666230907115818
Source: Endocrine, Metabolic and Immune Disorders Drug Targets - September 11, 2023 Category: Endocrinology Authors: Sandipan Jana Srijon Gayen Barun Dasgupta Seha Singha Jayashree Mondal Amit Kar Abhimanyu Nepal Suparna Ghosh Rajan Rajabalaya Sheba R David Ashok Kumar Balaraman Asis Bala Pulok K Mukerjee Pallab Kanti Haldar Source Type: research

Idiopathic Mesenteric Phlebosclerosis Secondary to Chinese Herbal Medicine Intake in an Older Adult
Am J Trop Med Hyg. 2023 Sep 11:tpmd220772. doi: 10.4269/ajtmh.22-0772. Online ahead of print.NO ABSTRACTPMID:37696511 | DOI:10.4269/ajtmh.22-0772
Source: The American Journal of Tropical Medicine and Hygiene - September 11, 2023 Category: Tropical Medicine Authors: Akira Kawashima Akira Shimomura Takeshi Inagaki Source Type: research

Hypolipidemic effect of β-caryophyllene in high fat diet and fructose induced type-2 diabetic adult male rats
Bioinformation. 2022 Nov 30;18(11):1087-1091. doi: 10.6026/973206300181087. eCollection 2022.ABSTRACTSkeletal muscle is responsible for the majority of insulin-stimulated whole-body glucose elimination, under normal circumstances. High dietary fat consumption increases stored fat mass and is a major risk factor for metabolic disorders. The conventional pharmacological treatments are associated with many adverse side effects and high rates of secondary failure which lead to an increasing demand for natural products with anti-diabetic activity and lesser side effects. β-Caryophyllene is a naturally occurring sequiterpene th...
Source: Bioinformation - September 11, 2023 Category: Bioinformatics Authors: Vadivel Mani Manikandan Balraj Nithya Rajapandian Chaitra Jinka Shyamaladevi Babu Source Type: research

< em > In vitro < /em > antimicrobial and cytotoxic activity of Neem and Kirata herbal formulation mediated Silver nanoparticles
This study aimed to determine the antimicrobial and cytotoxic activity of Neem and Kirata herbal formulation-mediated silver nanoparticles against oral biofilm. The green synthesis of Neem and Kirata herbal formulation-mediated silver nanoparticles was done. The antimicrobial action against the strains of Candida albicans, Staphylococcus aureus, Enterococcus faecalis, and Streptococcus mutans were assessed. The results showed that the newly formulated nanoparticle had effective anti-microbial properties and decreased cytotoxic properties which make it advantageous for clinical applications and treatment modalities. It show...
Source: Bioinformation - September 11, 2023 Category: Bioinformatics Authors: Rebekah R Saravana Dinesh Sp Nivethigaa B Rajeshkumar S Source Type: research

Effect of β-sitosterol on insulin resistance & amp; protein expression of insulin signalling molecules in quadriceps muscle of high fat diet-induced type-2 diabetic rats
Bioinformation. 2022 Nov 30;18(11):1098-1104. doi: 10.6026/973206300181098. eCollection 2022.ABSTRACTChanges in life style, such as high-calorie diet intake and lack of exercise, have increased the global prevalence of obesity and diabetes. The major pathophysiological event contributing to the development of type 2 diabetes mellitus is the target tissues to insulin action. Currently available drugs are unsuccessful for the treatment of type 2 diabetes due to their unwanted side effects. Hence, search drugs, from plant sources. β-sitosterol is plant sterols with structurally almost like that of cholesterol. It is widely p...
Source: Bioinformation - September 11, 2023 Category: Bioinformatics Authors: Gayathri Sekar Merlin G Madhan Krishnan Shyamaladevi Babu Padmini K Pushpa Konduru Mangai S Source Type: research

Investigation on anti-diabetic efficacy of a Cucurbitaceae food plant from the North-East region of India: Exploring the molecular mechanism through modulation of oxidative stress and glycosylated hemoglobin (HbA1c)
CONCLUSION: Based on the current evaluation, it was found that EASH exhibited encouraging hypoglycemic effects in diabetic rats induced by a low dose of STZ and high-fat diet, which warrants further investigation.PMID:37691221 | DOI:10.2174/1871530323666230907115818
Source: Endocrine, Metabolic and Immune Disorders Drug Targets - September 11, 2023 Category: Endocrinology Authors: Sandipan Jana Srijon Gayen Barun Dasgupta Seha Singha Jayashree Mondal Amit Kar Abhimanyu Nepal Suparna Ghosh Rajan Rajabalaya Sheba R David Ashok Kumar Balaraman Asis Bala Pulok K Mukerjee Pallab Kanti Haldar Source Type: research

Kaempferia parviflora rhizome extract exerts anti-obesity effect in high-fat diet-induced obese C57BL/6N mice
Food Nutr Res. 2023 Aug 23;67. doi: 10.29219/fnr.v67.9413. eCollection 2023.ABSTRACTKaempferia parviflora (KP) rhizome, also called black ginger, has been used as a herbal medicine for many centuries. This current study was aimed at exploring whether KP rhizome extract (KPE) had anti-obesity effects and the mechanism involved. Five-week-old C57BL/6N male mice were allocated into five groups for 8-week feeding with control diet (CD), high-fat diet (HFD), HFD + 150 mg/kg body weight (BW)/day KPE (HFD+K150), HFD + 300 mg/kg BW/day KPE (HFD+K300), and HFD + 600 mg/kg BW/day KPE (HFD+K600). KPE decreased BW, body fat mass, adip...
Source: Food and Nutrition Research - September 11, 2023 Category: Nutrition Authors: Hyun Sook Lee Young Eun Jeon Riyo Awa Susumu Yoshino Eun Ji Kim Source Type: research

A (Traditional Chinese Medicine) TCM-Inspired Doxorubicin Resistance Reversing Strategy: Preparation, Characterization, and Application of a Co-loaded pH-Sensitive Liposome
In this study, nano-strategy for combined medication of active compounds from traditional Chinese medicine herbs was proposed to achieve the synergistic effects of inhibiting the doxorubicin (DOX) resistance, reducing the cardio-toxicity, and improving the treatment efficacy simultaneously. Dihydroartemisinin (DHA) and tetrandrine (TET) were co-delivered for the first time to treat DOX resistance of breast cancer with multi-pathway mechanism. Tumor micro-environment sensitivity prescription was adopted to enhance the reversal effect of DOX resistance nearly 50 times (resistance index, RI was 46.70) and uptake ability. The ...
Source: AAPS PharmSciTech - September 11, 2023 Category: Drugs & Pharmacology Authors: Xueyan Zhang Hua Liu Na Li Jiayang Li Meng Wang Xiaoliang Ren Source Type: research

Curcumin/Fusidic Acid Bitherapy Loaded Mixed Micellar Nanogel for Acne Vulgaris Treatment: In Vitro and In Vivo Studies
In conclusion, micellar nanogel could enable the progressive effect of Cur (an antioxidant with reported antibiotic activity) on FA (antibiotic) and decrease the risk of emerging antibiotic resistance by enhancing the solubility and permeation of Cur.PMID:37697137 | DOI:10.1208/s12249-023-02641-5
Source: AAPS PharmSciTech - September 11, 2023 Category: Drugs & Pharmacology Authors: Raghda Abdel-Monem Eman S El-Leithy Ahmed Adel Alaa-Eldin Rania S Abdel-Rashid Source Type: research