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Management of physical symptoms in the absence of organic disease
This article looks at current nomenclature, assessment and management options that can be provided by the physician to improve clinical outcomes in this patient group in the acute medical unit.
Source: Medicine - December 16, 2020 Category: Internal Medicine Authors: Anne-Mary O. Abe Tags: Acute medicine I Source Type: research

The Medial Femoral Condyle Flap in the Pediatric Patient
Conclusions: The authors present the first series of corticocancellous medial femoral condyle free flaps in the pediatric population along with a novel technique to avoid injury to the physis in skeletally immature patients. This technique is effective for a variety of skeletal defects or nonunions and is safe for growing patients without causing physeal arrest or growth disturbance. CLINICAL QUESTION/LEVEL OF EVIDENCE: Therapeutic, IV.
Source: Plastic and Reconstructive Surgery - April 1, 2021 Category: Cosmetic Surgery Tags: Pediatric/Craniofacial: Original Articles Source Type: research

Pediatric Cranioplasty Using Hydroxyapatite Cement: A Retrospective Review and Preliminary Computational Model
Conclusion Pediatric cranioplasty is a necessary procedure for cranial defects with a relatively higher rate of failure than adults. Here, we use hydroxyapatite cement to perform the procedure while creating a preliminary computational model to understand osteointegration. Based on the findings, cranioplasty shape may alter rate of integration and lead to higher success rates.
Source: Pediatric Neurosurgery - November 30, 2021 Category: Neurosurgery Source Type: research

Prediction of Bloodstream Infection in Pediatric Acute Leukemia by Microbiota and Volatile Organic Compounds Analysis
Conclusion: Microbiota and fecal VOC could serve as biomarkers to predict BSI in pediatric leukemia.
Source: Journal of Pediatric Hematology Oncology - January 1, 2022 Category: Hematology Tags: Online Articles: Original Articles Source Type: research

Diagnostic Tests in Pediatric Constipation
Constipation is one of the most common gastrointestinal symptoms in children. With a median reported prevalence of 12%, it accounts for about 25% of all pediatric gastroenterology consultations. The majority of children experiences functional constipation and do not usually require any diagnostic testing. For those children not responding to conventional medical treatment or in the presence of a more significant clinical picture, however, an accurate instrumental assessment is usually recommended to evaluate either the underlying pathophysiologic mechanisms or a possible organic etiology. The present review analyzes the po...
Source: Journal of Pediatric Gastroenterology and Nutrition - March 24, 2018 Category: Gastroenterology Tags: Reviews Source Type: research

Pediatric Anti-NMDA-R Encephalitis: Presentation, Diagnosis, and Management.
Abstract Immune- mediated encephalitis is the most common cause of encephalitis after infection in children and adults. Although this disease process was identified nearly 20 years ago, the variety of clinical presentations and the lack of specific diagnostic criteria can make the identification of anti-N-methyl-D-aspartate receptors (NMDA-R) encephalitis challenging. Moreover, identifying NMDA-R antibodies in blood or cerebrospinal fluid can take days to weeks, and thus clinicians need to have a high index of suspicion to investigate for this disease in patients who may appear to have an overlap of neurologic and...
Source: Pediatric Annals - September 30, 2019 Category: Pediatrics Authors: Gerstle K, Hur MH, Moussa T Tags: Pediatr Ann Source Type: research

Physician Palliative Education Associated With High Use of Hospice Care Service
CONCLUSIONS: Physicians' palliative education was found to be an independent factor associated with higher use of hospice care. The findings suggest increasing palliative and hospice education among physicians so that they can ensure that their patients have high-quality end-of-life medical care in an aging society.PMID:33960206 | DOI:10.1177/10499091211014160
Source: The American Journal of Hospice and Palliative Care - May 7, 2021 Category: Palliative Care Authors: Mei-Hsing Chuang Fang-Niarn Lee Yih-Tsong Shiau Hsiu-Yi Shen Chih-Ching Lee Saint Shiou-Sheng Chen Sheng-Jean Huang Source Type: research

Longitudinal changes of mental health problems in children and adolescents treated in a primary care-based health-coaching programme - results of the PrimA-QuO cohort study
CONCLUSION: This evaluation of the HC programme could not prove a clinically relevant intervention's effect on the MHP developmental course. Nevertheless, (HC) paediatricians have crucial potential to improve the care of MHP patients. Targeting families with less access to support measures might help reduce the burden of MHP and be a step towards continuous improvement of care.PMID:35996092 | PMC:PMC9396915 | DOI:10.1186/s12875-022-01780-1
Source: Primary Care - August 22, 2022 Category: Primary Care Authors: Siona Decke Karina Hamacher Martin Lang Otto Laub Lars Schwettmann Ralf Strobl Eva Grill Source Type: research

Digital remains should be treated with the same care and respect as physical remains
(University of Oxford) An Oxford University study published in Nature advises that people's digital remains, such as, social media activity and online history, should be viewed in the same way as the human body, and treated with care and respect rather than manipulated for commercial gain.The paper suggests regulation akin to those used in museums and commercial use of organic human remains, is the best way to create explicit boundaries around acceptable afterlife activity and grief exploitation.
Source: EurekAlert! - Medicine and Health - April 17, 2018 Category: International Medicine & Public Health Source Type: news

Osmolarity and partitioning of fluids
This article first outlines definitions and descriptions of key terms that will be used in the discussions that follow, including osmolarity, osmolality, osmotic and oncotic pressure. The physicochemical properties of water, ions and organic molecules are discussed in terms of their biological roles. Similarly, the interactions of amphipathic molecules and their three-dimensional structures in aqueous and non-aqueous environments are then explored. The movement of solutes and solvents across semipermeable membranes is considered and an assessment is made of the contribution of such mechanisms to normal physiology. Firstly,...
Source: Anaesthesia and intensive care medicine - August 1, 2018 Category: Anesthesiology Source Type: research

Macronutrients, minerals, vitamins and energy
Publication date: Available online 1 February 2020Source: Anaesthesia & Intensive Care MedicineAuthor(s): Rahul Costa-Pinto, Dashiell GantnerAbstractMacronutrients comprise carbohydrates, fats and proteins and make up most of the body's soft tissue structure. Carbohydrates are organic molecules made of carbon, hydrogen and oxygen atoms. Fats are composed of carbon, hydrogen and oxygen, but the proportion of oxygen atoms to carbon and hydrogen is lower than in carbohydrates. Proteins are usually made up of more than 100 amino acids linked into chains by peptide bonds. Amino acids consist of an asymmetrical carbon atom with ...
Source: Anaesthesia and intensive care medicine - February 1, 2020 Category: Anesthesiology Source Type: research