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Roaming behavior of the owned domestic cats (Felis catus) with possible roles in the transmission of Opisthorchis viverrini in the endemic area in Khon Kaen, Thailand
Acta Trop. 2023 Sep 1:107013. doi: 10.1016/j.actatropica.2023.107013. Online ahead of print.ABSTRACTIn the endemic area of the liver fluke (Opisthorchis viverrini) infection, effective control of opisthorchiasis using One Health approaches requires transmission interruption in all hosts in the parasite life cycle. Owned domestic cats (Felis catus) are considered an important species among mammalian reservoirs. Similar to humans, household cats become infected by eating raw, contaminated fish and spread the O. viverrini eggs to the environment by defecation. In rural areas, cat owners usually feed their cats with human food...
Source: Acta Tropica - September 3, 2023 Category: Infectious Diseases Authors: Makoto Sakamoto Songkiad Upontain Pornphutthachat Sota Jeffrey Mariner Prasarn Tangkawattana Sirikachorn Tangkawattana Source Type: research
Phosphatidylethanolamine alleviates OX-LDL-induced macrophage inflammation by upregulating autophagy and inhibiting NLRP1 inflammasome activation
In conclusion, we elucidated the role of the CD36-NLRP1-caspase-1 signaling pathway in OX-LDL-induced inflammation in fish and revealed for the first time that altering PE abundance in OX-LDL-treated cells could alleviate inflammasome-mediated inflammation by inducing autophagy. Given the relationship between OX-LDL-induced inflammation and atherosclerosis, this study prompts that the use of PE-rich foods promises to be a new strategy for atherosclerosis treatment in vertebrates.PMID:37660837 | DOI:10.1016/j.freeradbiomed.2023.08.031
Source: Free Radical Biology and Medicine - September 3, 2023 Category: Biology Authors: Tingting Hao Wei Fang Dan Xu Qiang Chen Qiangde Liu Kun Cui Xiufei Cao Yueru Li Kangsen Mai Qinghui Ai Source Type: research
Roaming behavior of the owned domestic cats (Felis catus) with possible roles in the transmission of Opisthorchis viverrini in the endemic area in Khon Kaen, Thailand
Acta Trop. 2023 Sep 1:107013. doi: 10.1016/j.actatropica.2023.107013. Online ahead of print.ABSTRACTIn the endemic area of the liver fluke (Opisthorchis viverrini) infection, effective control of opisthorchiasis using One Health approaches requires transmission interruption in all hosts in the parasite life cycle. Owned domestic cats (Felis catus) are considered an important species among mammalian reservoirs. Similar to humans, household cats become infected by eating raw, contaminated fish and spread the O. viverrini eggs to the environment by defecation. In rural areas, cat owners usually feed their cats with human food...
Source: Acta Tropica - September 3, 2023 Category: Infectious Diseases Authors: Makoto Sakamoto Songkiad Upontain Pornphutthachat Sota Jeffrey Mariner Prasarn Tangkawattana Sirikachorn Tangkawattana Source Type: research
Development of an indirect ELISA for detection of the adaptive immune response of black carp (Mylopharyngodon piceus)
J Immunol Methods. 2023 Sep 1:113550. doi: 10.1016/j.jim.2023.113550. Online ahead of print.ABSTRACTBlack carp (Mylopharyngodon piceus) is an important fishery resource and the main breeding target in China. Due to the lack of an assay of immunoglobulin M (IgM) antibodies in black carp, there is no effective method to evaluate adaptive immune response, which limits immunological studies and vaccine development. The present study used mAbs (monoclonal antibodies) against serum IgM of grass carp as capture antibodies. The results of Western blot analysis indicated that these antibodies had strong affinity and specificity to ...
Source: Journal of Immunological Methods - September 3, 2023 Category: Allergy & Immunology Authors: Tongtong Wang Shanshan Jin L V Ruoxuan Yuting Meng Guozhong Li Yuxing Han Qiusheng Zhang Source Type: research
Meiotic segregation and post-meiotic drive of the Festuca pratensis B chromosome
Chromosome Res. 2023 Sep 2;31(3):26. doi: 10.1007/s10577-023-09728-6.ABSTRACTIn many species, the transmission of B chromosomes (Bs) does not follow the Mendelian laws of equal segregation and independent assortment. This deviation results in transmission rates of Bs higher than 0.5, a process known as "chromosome drive". Here, we studied the behavior of the 103 Mbp-large B chromosome of Festuca pratensis during all meiotic and mitotic stages of microsporogenesis. Mostly, the B chromosome of F. pratensis segregates during meiosis like standard A chromosomes (As). In some cases, the B passes through meiosis in a non-Mendeli...
Source: Chromosome Research - September 2, 2023 Category: Genetics & Stem Cells Authors: Rahman Ebrahimzadegan J örg Fuchs Jianyong Chen Veit Schubert Armin Meister Andreas Houben Ghader Mirzaghaderi Source Type: research
Potential Role of Selenium in Modifying the Effect of Maternal Methylmercury Exposure on Child Neurodevelopment-A Review
Neurotoxicology. 2023 Aug 31:S0161-813X(23)00105-5. doi: 10.1016/j.neuro.2023.08.003. Online ahead of print.ABSTRACTSelenium (Se) is an essential trace element for normal neurodevelopment. It is incorporated into multiple selenoenzymes which have roles in the brain and neurological function, the synthesis of thyroid hormones, the antioxidant defense system, DNA synthesis, and reproduction. Fish is a source of both Se and neurotoxic methylmercury (MeHg). Selenium is known to ameliorate the effects of MeHg in experimental animals, but studies in children exposed to both Se and MeHg through prenatal fish consumption have been...
Source: Neurotoxicology - September 2, 2023 Category: Neurology Authors: Maria Wesolowska Alison J Yeates Emeir M McSorley Edwin van Wijngaarden Conrad F Shamlaye Gary J Myers J J Strain Maria S Mulhern Source Type: research
Tricyclic hydrocarbon fluorene attenuates ventricular ionic currents and pressure development in the navaga cod
Comp Biochem Physiol C Toxicol Pharmacol. 2023 Aug 31:109736. doi: 10.1016/j.cbpc.2023.109736. Online ahead of print.ABSTRACTThe release of polycyclic aromatic hydrocarbons (PAHs) into environment due to oil and diesel fuel spills is a serious threat to arctic fish populations. PAHs produce multiple toxic effects in fish, but disturbance of electrical and contractile activity of the heart seems to be the most negative effect. Our study was focused on the effects of fluorene, a tricyclic PAH partially resembling the well-investigated phenanthrene, on major ionic currents and action potential (AP) waveform in isolated ventri...
Source: Comparative biochemistry and physiology. Toxicology and pharmacology : CBP - September 2, 2023 Category: Biochemistry Authors: Denis V Abramochkin Tatiana S Filatova Vladislav S Kuzmin Yuri I Voronkov Andre Kamkin Holly A Shiels Source Type: research
Omics techniques reveal the toxicity mechanisms of three antiepileptic drugs to juvenile zebrafish (Danio rerio) brain and liver
In this study, juvenile zebrafish were exposed to a sub-lethal concentration (100 μg/L) of OCBZ, LTG, and CBZ for 28 d, after which indicators of oxidative stress (i.e. superoxide dismutase (SOD) activity, catalase (CAT) activity, and malondialdehyde (MDA) level) and neurotoxicity (i.e. acetylcholinesterase (AChE) activity, γ-aminobutyric acid (GABA) level, and glutamic acid (Glu) level) were measured. Brain SOD activity was significantly increased by three AEDs, while brain CAT activity was significantly inhibited by LTG and CBZ. Liver SOD activity was significantly enhanced by CBZ, and liver CAT activity was significan...
Source: Aquatic Toxicology - September 2, 2023 Category: Toxicology Authors: Huiting Yang Xiaohong Gu Huihui Chen Qingfei Zeng Zhigang Mao You Ge Source Type: research
Cold Stress Induces Apoptosis in Silver Pomfret via DUSP-JNK Pathway
Mar Biotechnol (NY). 2023 Sep 2. doi: 10.1007/s10126-023-10245-0. Online ahead of print.ABSTRACTWe cultured silver pomfret for 20 days, decreasing water temperature from 18 to 8 ℃, and sampled muscle every 5 days. Muscle fiber degeneration and apoptosis began to increase at 13 ℃ detected by HE and TUNEL staining. Further analysis of transcriptome revealed that several apoptosis-related pathways were highly enriched by differentially expressed genes (DEGs). We analyzed 10 DEGs from these pathways by RT-qPCR during the temperature-decreasing process. JNK1, PIDD, CytC, Casp 3, and GADD45 were up-regulated after 15 and 20 ...
Source: Marine Biotechnology - September 2, 2023 Category: Biotechnology Authors: Jiabao Hu Man Zhang Kaiheng Yan Youyi Zhang Yaya Li Jiajie Zhu Guanlin Wang Xiangbing Wang Yuanbo Li Xiang Huang Jie Tang Rongyue Zheng Shanliang Xu Danli Wang Yajun Wang Xiaojun Yan Source Type: research
Superior detection rate of plasma cell FISH using FACS-FISH
CONCLUSIONS: Fluorescence-activated cell sorting-FISH is an efficient PC purification strategy that affords significant improvement in diagnostic yield and decreases workflow requirements in comparison with cIg-FISH.PMID:37658775 | DOI:10.1093/ajcp/aqad108
Source: American Journal of Clinical Pathology - September 2, 2023 Category: Pathology Authors: Marie-France Gagnon Sally M Midthun James A Fangel Cynthia M Schuh Ivy M Luoma Kathryn E Pearce Reid G Meyer Sikander Ailawadhi Mariano J Arribas Esteban Braggio Rafael Fonseca S Vincent Rajkumar Cinthya Zepeda-Mendoza Xinjie Xu Patricia T Greipp Michael Source Type: research
Potential Role of Selenium in Modifying the Effect of Maternal Methylmercury Exposure on Child Neurodevelopment-A Review
Neurotoxicology. 2023 Aug 31:S0161-813X(23)00105-5. doi: 10.1016/j.neuro.2023.08.003. Online ahead of print.ABSTRACTSelenium (Se) is an essential trace element for normal neurodevelopment. It is incorporated into multiple selenoenzymes which have roles in the brain and neurological function, the synthesis of thyroid hormones, the antioxidant defense system, DNA synthesis, and reproduction. Fish is a source of both Se and neurotoxic methylmercury (MeHg). Selenium is known to ameliorate the effects of MeHg in experimental animals, but studies in children exposed to both Se and MeHg through prenatal fish consumption have been...
Source: Neurotoxicology - September 2, 2023 Category: Neurology Authors: Maria Wesolowska Alison J Yeates Emeir M McSorley Edwin van Wijngaarden Conrad F Shamlaye Gary J Myers J J Strain Maria S Mulhern Source Type: research
Tricyclic hydrocarbon fluorene attenuates ventricular ionic currents and pressure development in the navaga cod
Comp Biochem Physiol C Toxicol Pharmacol. 2023 Aug 31:109736. doi: 10.1016/j.cbpc.2023.109736. Online ahead of print.ABSTRACTThe release of polycyclic aromatic hydrocarbons (PAHs) into environment due to oil and diesel fuel spills is a serious threat to arctic fish populations. PAHs produce multiple toxic effects in fish, but disturbance of electrical and contractile activity of the heart seems to be the most negative effect. Our study was focused on the effects of fluorene, a tricyclic PAH partially resembling the well-investigated phenanthrene, on major ionic currents and action potential (AP) waveform in isolated ventri...
Source: Comparative biochemistry and physiology. Toxicology and pharmacology : CBP - September 2, 2023 Category: Biochemistry Authors: Denis V Abramochkin Tatiana S Filatova Vladislav S Kuzmin Yuri I Voronkov Andre Kamkin Holly A Shiels Source Type: research
Potential Role of Selenium in Modifying the Effect of Maternal Methylmercury Exposure on Child Neurodevelopment-A Review
Neurotoxicology. 2023 Aug 31:S0161-813X(23)00105-5. doi: 10.1016/j.neuro.2023.08.003. Online ahead of print.ABSTRACTSelenium (Se) is an essential trace element for normal neurodevelopment. It is incorporated into multiple selenoenzymes which have roles in the brain and neurological function, the synthesis of thyroid hormones, the antioxidant defense system, DNA synthesis, and reproduction. Fish is a source of both Se and neurotoxic methylmercury (MeHg). Selenium is known to ameliorate the effects of MeHg in experimental animals, but studies in children exposed to both Se and MeHg through prenatal fish consumption have been...
Source: Neurotoxicology - September 2, 2023 Category: Neurology Authors: Maria Wesolowska Alison J Yeates Emeir M McSorley Edwin van Wijngaarden Conrad F Shamlaye Gary J Myers J J Strain Maria S Mulhern Source Type: research
Omics techniques reveal the toxicity mechanisms of three antiepileptic drugs to juvenile zebrafish (Danio rerio) brain and liver
In this study, juvenile zebrafish were exposed to a sub-lethal concentration (100 μg/L) of OCBZ, LTG, and CBZ for 28 d, after which indicators of oxidative stress (i.e. superoxide dismutase (SOD) activity, catalase (CAT) activity, and malondialdehyde (MDA) level) and neurotoxicity (i.e. acetylcholinesterase (AChE) activity, γ-aminobutyric acid (GABA) level, and glutamic acid (Glu) level) were measured. Brain SOD activity was significantly increased by three AEDs, while brain CAT activity was significantly inhibited by LTG and CBZ. Liver SOD activity was significantly enhanced by CBZ, and liver CAT activity was significan...
Source: Aquatic Toxicology - September 2, 2023 Category: Toxicology Authors: Huiting Yang Xiaohong Gu Huihui Chen Qingfei Zeng Zhigang Mao You Ge Source Type: research
Effect of chemical modification of κ-carrageenan on its inhibitory effect against heterocyclic amine (HAs) formation in roasted tilapia fish patties
Int J Biol Macromol. 2023 Aug 31:126586. doi: 10.1016/j.ijbiomac.2023.126586. Online ahead of print.ABSTRACTSulfated κ-carrageenan (S-KC), carboxymethylated κ-carrageenan (C-KC), acetylated κ-carrageenan (A-KC) and phosphorylated κ-carrageenan (P-KC) were synthesized and tested for their inhibitory effect on heterocyclic amine (HAs) formation in roasted tilapia fish patties. Fish patties with 1 % of each hydrocolloid prepared by 90 % of fish and 10 % of an aqueous hydrocolloid dispersion were determined for HAs-levels after roasting. P-KC showed the strongest inhibitory effect against total HAs formation (20.95 %). Mor...
Source: International Journal of Biological Macromolecules - September 2, 2023 Category: Biochemistry Authors: Tian Xue Qingqing Jiang Leiwen Xiang Jianbo Xiao Daming Fan Mingfu Wang Yueliang Zhao Source Type: research
