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Nutrition: Diets
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Mandibular glands secrete 24-methylenecholesterol into honey bee (Apis mellifera) food jelly
Insect Biochem Mol Biol. 2023 Sep 14:104011. doi: 10.1016/j.ibmb.2023.104011. Online ahead of print.ABSTRACTHoney bee (Apis mellifera) workers feed their larvae with food jelly that is secreted by specialized glands in their heads - the hypopharyngeal and the mandibular glands. Food jelly contains all the nutrients the larvae need to develop into adult honey bees, including essential dietary sterols. The main sterol in food jelly, 24-methylenecholesterol (24 MC), is pollen-derived and delivered in food jelly to the larvae in a complex with two proteins, major royal jelly protein 1 (MRJP1) and apisim. Whereas the proteins a...
Source: Insect Biochemistry and Molecular Biology - September 16, 2023 Category: Biochemistry Authors: Anja Buttstedt Christian W W Pirk Abdullahi A Yusuf Source Type: research
Tumor lipid metabolism: a mechanistic link between diet and cancer progression
Curr Opin Biotechnol. 2023 Sep 13;84:102993. doi: 10.1016/j.copbio.2023.102993. Online ahead of print.ABSTRACTThe potential for 'anti-cancer' diets to markedly alter cancer risk and prognosis has captured the imagination of patients, physicians, and researchers alike, but many of these dietary recommendations come from correlative studies that attribute certain diets to altered cancer risk. While provocative, little is known about the molecular mechanisms behind how these dietary interventions impact cancer progression. Within this context, however, changes in tumor lipid metabolism are emerging as a key contributor. In th...
Source: Current Opinion in Biotechnology - September 16, 2023 Category: Biotechnology Authors: Yu-Jin Jeong Thomas J Rogers Carolyn E Anderson Evan C Lien Source Type: research
Development of a framework for risk assessment of dietary carcinogens
Food Chem Toxicol. 2023 Sep 14:114022. doi: 10.1016/j.fct.2023.114022. Online ahead of print.ABSTRACTAlthough there are a number of guidance documents and frameworks for evaluation of carcinogenicity, none of the current methods fully reflects the state of the science. Common limitations include the absence of dose-response assessment and not considering the impact of differing exposure patterns (e.g., intermittent, high peaks vs. lower, continuous exposures). To address these issues, we have developed a framework for risk assessment of dietary carcinogens. This framework includes an enhanced approach for weight of evidenc...
Source: Food and Chemical Toxicology - September 16, 2023 Category: Food Science Authors: Christopher A Bates Lynne T Haber Martha M Moore Rita Schoeny Andrew Maier Source Type: research
Dietary management of eosinophilic oesophagitis
Med J Aust. 2023 Sep 16. doi: 10.5694/mja2.52101. Online ahead of print.NO ABSTRACTPMID:37716710 | DOI:10.5694/mja2.52101
Source: Med J Aust - September 16, 2023 Category: General Medicine Authors: Jessica Fitzpatrick Sarah L Melton Rebecca E Burgell Source Type: research
Pancreastatin inhibitor PSTi8 ameliorates insulin resistance by decreasing fat accumulation and oxidative stress in high-fat diet-fed mice
Amino Acids. 2023 Sep 16. doi: 10.1007/s00726-023-03332-y. Online ahead of print.ABSTRACTAbnormal fat accumulation, enhanced free fatty acids (FFA) release, and their metabolites cause insulin resistance (IR) in major glucose-lipid metabolic organs such as skeletal muscle and adipose tissue. However, excessive lipolysis and FFA release from adipose tissue elevate plasma FFA levels leading to oxidative stress and skeletal muscle IR. Indeed, in obese individuals, there is enhanced pro-inflammatory secretion from adipose tissue influencing insulin signaling in skeletal muscles. Here, we investigated the effect of PSTi8 on FFA...
Source: Amino Acids - September 16, 2023 Category: Biochemistry Authors: Richa Garg Arun Agarwal Roshan Katekar Umesh Kumar Goand Naveen Singh Shubhi Yadav Shivam Rathaur Saurabh Verma Debalina Maity Sachin Vishwakarma Jiaur R Gayen Source Type: research
Development of a framework for risk assessment of dietary carcinogens
Food Chem Toxicol. 2023 Sep 14:114022. doi: 10.1016/j.fct.2023.114022. Online ahead of print.ABSTRACTAlthough there are a number of guidance documents and frameworks for evaluation of carcinogenicity, none of the current methods fully reflects the state of the science. Common limitations include the absence of dose-response assessment and not considering the impact of differing exposure patterns (e.g., intermittent, high peaks vs. lower, continuous exposures). To address these issues, we have developed a framework for risk assessment of dietary carcinogens. This framework includes an enhanced approach for weight of evidenc...
Source: Food and Chemical Toxicology - September 16, 2023 Category: Food Science Authors: Christopher A Bates Lynne T Haber Martha M Moore Rita Schoeny Andrew Maier Source Type: research
Pancreastatin inhibitor PSTi8 ameliorates insulin resistance by decreasing fat accumulation and oxidative stress in high-fat diet-fed mice
Amino Acids. 2023 Sep 16. doi: 10.1007/s00726-023-03332-y. Online ahead of print.ABSTRACTAbnormal fat accumulation, enhanced free fatty acids (FFA) release, and their metabolites cause insulin resistance (IR) in major glucose-lipid metabolic organs such as skeletal muscle and adipose tissue. However, excessive lipolysis and FFA release from adipose tissue elevate plasma FFA levels leading to oxidative stress and skeletal muscle IR. Indeed, in obese individuals, there is enhanced pro-inflammatory secretion from adipose tissue influencing insulin signaling in skeletal muscles. Here, we investigated the effect of PSTi8 on FFA...
Source: Amino Acids - September 16, 2023 Category: Biochemistry Authors: Richa Garg Arun Agarwal Roshan Katekar Umesh Kumar Goand Naveen Singh Shubhi Yadav Shivam Rathaur Saurabh Verma Debalina Maity Sachin Vishwakarma Jiaur R Gayen Source Type: research
Higher habitual dietary intakes of flavanols and anthocyanins differentially associate with lower incidence of ischemic stroke subtypes-A follow-up analysis
CONCLUSIONS: Higher habitual intakes of flavanols and anthocyanins are differentially associated with lower risk of ischemic stroke from atherosclerosis and/or cardioembolism, but not with other subtypes.PMID:37716608 | DOI:10.1016/j.tjnut.2023.09.011
Source: Atherosclerosis - September 16, 2023 Category: Cardiology Authors: Benjamin H Parmenter Pratik Pokharel Frederik Dalgaard Kevin Murray Aed ín Cassidy Catherine P Bondonno Joshua R Lewis Cecilie Kyr ø Anne Tj ønneland Kim Overvad Jonathan M Hodgson Nicola P Bondonno Source Type: research
Trade liberalization and nutrition transition: Evidence from China
Econ Hum Biol. 2023 Sep 9;51:101304. doi: 10.1016/j.ehb.2023.101304. Online ahead of print.ABSTRACTWe examine the impact of trade liberalization on the nutrition transition between 1997 and 2011. Our findings demonstrate that the reduction in tariff rates has had a significant effect on the dietary patterns of both rural and urban residents in the country. With the decrease in tariffs, there has been a noticeable increase in the consumption of animal products (such as meat and aquatic products), vegetables, beans and nuts, as well as packaged and processed foods. Simultaneously, there has been a decrease in the demand for ...
Source: Economics and Human Biology - September 16, 2023 Category: Biology Authors: Xu Tian Faqin Lin Source Type: research
Zhizi-Chuanxiong herb pair alleviates atherosclerosis progression in ApoE < sup > -/- < /sup > mice by promoting the methylation of FGFR3 to inhibit MAPK/ERK-mediated apoptosis
CONCLUSION: Our findings suggest that ZCHP can effectively attenuate AS progression by inhibiting MAPK/ERK signaling-mediated apoptosis via FGFR3 hypermethylation in the promoter region.PMID:37716492 | DOI:10.1016/j.jep.2023.117188
Source: Atherosclerosis - September 16, 2023 Category: Cardiology Authors: Yan Zhang Dandan Li Zijun Jia Jun Mei Ya Wang Ying Zhang Qingbing Zhou Fengqin Xu Source Type: research
Tumor lipid metabolism: a mechanistic link between diet and cancer progression
Curr Opin Biotechnol. 2023 Sep 13;84:102993. doi: 10.1016/j.copbio.2023.102993. Online ahead of print.ABSTRACTThe potential for 'anti-cancer' diets to markedly alter cancer risk and prognosis has captured the imagination of patients, physicians, and researchers alike, but many of these dietary recommendations come from correlative studies that attribute certain diets to altered cancer risk. While provocative, little is known about the molecular mechanisms behind how these dietary interventions impact cancer progression. Within this context, however, changes in tumor lipid metabolism are emerging as a key contributor. In th...
Source: Current Opinion in Biotechnology - September 16, 2023 Category: Biotechnology Authors: Yu-Jin Jeong Thomas J Rogers Carolyn E Anderson Evan C Lien Source Type: research
Two-month period of 500 mg lecithin-based delivery form of quercetin daily dietary supplementation counterbalances chronic fatigue symptoms: A double-blind placebo controlled clinical trial
CONCLUSION: The quercetin supplementation counterbalances CF symptoms.PMID:37716119 | DOI:10.1016/j.biopha.2023.115453
Source: Biomedicine and pharmacotherapy = Biomedecine and pharmacotherapie - September 16, 2023 Category: Drugs & Pharmacology Authors: Mariangela Rondanelli Antonella Riva Giovanna Petrangolini Clara Gasparri Simone Perna Source Type: research
Aflatoxin B1 triggers apoptosis in rabbit hepatocytes via mediating oxidative stress and switching on the mitochondrial apoptosis pathway
Ecotoxicol Environ Saf. 2023 Sep 14;264:115478. doi: 10.1016/j.ecoenv.2023.115478. Online ahead of print.ABSTRACTAflatoxin B1 (AFB1) is considered the most toxic carcinogenic compound, and exposure to AFB1 is highly associated with hepatocellular carcinoma. The aim of this study was to investigate the effects of different doses of AFB1 on growth performance and the liver of rabbits, as well as explore its underlying mechanisms. A total of eighty 30-day-old meat rabbits were randomly divided into four treatments. The control group was fed a pollution-free diet, while the AFL, AFM, and AFH groups were fed contaminated diets ...
Source: Ecotoxicology and Environmental Safety - September 16, 2023 Category: Environmental Health Authors: Lu Zhang Shaowen Shi Ying Liu Yuqing Cui Yixuan Zhu Yongzhan Bao Baojiang Chen Wanyu Shi Source Type: research
