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Total 1921 results found since Jan 2013.
Diseases of the Coronary Microcirculation: Diagnosis and Treatment
CONCLUSION: Approximately 25% of patients with CMD have symptoms that do not respond to intensive treatment with the currently available modalities. New treatments, including interventional therapies, are being studied. Their long-term benefit remains to be assessed and compared to that of the existing methods.PMID:37721132 | DOI:10.3238/arztebl.m2023.0205
Source: Deutsches Arzteblatt International - September 18, 2023 Category: General Medicine Authors: Helen Ullrich-Daub Steffen Daub Maximilian Olschewski Thomas M ünzel Tommaso Gori Source Type: research
Molecular Complex of HSIM-loaded Polymeric Nanoparticles: Potential Carriers in Osteoporosis
CONCLUSION: Bone-targeting nanoparticles incorporating functionalized simvastatin can target bone. Thus, in order to distribute simvastatin subcutaneously for the treatment of osteoporosis, the developed nanoparticles may act as a promising approach.PMID:37718521 | DOI:10.2174/1389450124666230915092910
Source: Current Drug Targets - September 18, 2023 Category: Drugs & Pharmacology Authors: Malkiet Kaur Manju Nagpal Amarjot Kaur Grewal Samrat Chauhan Chander Parkash Dora Thakur Gurjeet Singh Source Type: research
Diseases of the Coronary Microcirculation: Diagnosis and Treatment
CONCLUSION: Approximately 25% of patients with CMD have symptoms that do not respond to intensive treatment with the currently available modalities. New treatments, including interventional therapies, are being studied. Their long-term benefit remains to be assessed and compared to that of the existing methods.PMID:37721132 | DOI:10.3238/arztebl.m2023.0205
Source: Deutsches Arzteblatt International - September 18, 2023 Category: General Medicine Authors: Helen Ullrich-Daub Steffen Daub Maximilian Olschewski Thomas M ünzel Tommaso Gori Source Type: research
Molecular Complex of HSIM-loaded Polymeric Nanoparticles: Potential Carriers in Osteoporosis
CONCLUSION: Bone-targeting nanoparticles incorporating functionalized simvastatin can target bone. Thus, in order to distribute simvastatin subcutaneously for the treatment of osteoporosis, the developed nanoparticles may act as a promising approach.PMID:37718521 | DOI:10.2174/1389450124666230915092910
Source: Current Drug Targets - September 18, 2023 Category: Drugs & Pharmacology Authors: Malkiet Kaur Manju Nagpal Amarjot Kaur Grewal Samrat Chauhan Chander Parkash Dora Thakur Gurjeet Singh Source Type: research
Diseases of the Coronary Microcirculation: Diagnosis and Treatment
CONCLUSION: Approximately 25% of patients with CMD have symptoms that do not respond to intensive treatment with the currently available modalities. New treatments, including interventional therapies, are being studied. Their long-term benefit remains to be assessed and compared to that of the existing methods.PMID:37721132 | DOI:10.3238/arztebl.m2023.0205
Source: Deutsches Arzteblatt International - September 18, 2023 Category: General Medicine Authors: Helen Ullrich-Daub Steffen Daub Maximilian Olschewski Thomas M ünzel Tommaso Gori Source Type: research
3D interconnected porous PMMA scaffold integrating with advanced nanostructured CaP-based biomaterials for rapid bone repair and regeneration
J Mech Behav Biomed Mater. 2023 Sep 7;147:106106. doi: 10.1016/j.jmbbm.2023.106106. Online ahead of print.ABSTRACTBioactive scaffolds with polymer and nanostructured bioactive glass-based composites are promising materials for regenerative applications in consequence of close mimics of natural bone composition. Poly methyl methacrylate (PMMA) is a highly preferred thermoplastic polymer for orthopedic applications as it has good biocompatibility. Different kinds of bioactive, biodegradable as well as biocompatible biomaterial composites such as Bioglass (BG), Hydroxyapatite (Hap), and Tricalcium phosphate (TCP) can be integ...
Source: Journal of the Mechanical Behavior of Biomedical Materials - September 14, 2023 Category: Materials Science Authors: K Elakkiya P Bargavi S Balakumar Source Type: research
An electrokinetic-biocementation study for clay stabilisation using carbonic anhydrase-producing bacteria
This study investigates the feasibility of biocementing clay soil underneath a railway embankment of the UK rail network via carbonic anhydrase (CA) biocementation, implementing the treatments electrokinetically. Compared to previous biocementation studies using the ureolytic route, the CA pathway is attractive as CA-producing bacteria can sequester CO2 to produce biocement. Clay soil samples were treated electrokinetically using biostimulation and bioaugmentation conditions to induce biocementation. The effects of the treatment were assessed in terms of undrained shear strength using the cone penetration test, moisture co...
Source: Environmental Science and Pollution Research International - September 13, 2023 Category: Environmental Health Authors: Wilson Mwandira Maria Mavroulidou Anjali Satheesh Michael John Gunn Christopher Gray Diane Purchase Jonathan Garelick Source Type: research
Malignant hypercalcemia revealing a diffuse large B ‐cell lymphoma in a patient with a previous diagnosis of chronic myelomonocytic leukemia: An uncommon hematological coexistence
Key Clinical MessageA 76-year-old patient previously admitted to the cardiology department for replacement of a right ventricular lead on a double-chamber pacemaker was admitted to the internal medicine department 15 days after for bronchopneumopathy. His past medical history was relevant for Type 2 diabetes mellitus, heart failure due to dilated hypokinetic heart disease, transcatheter aortic valve implantation (TAVI), and chronic myelomonocytic leukemia (CMML-0) diagnosed in 2021. Twenty-four hours after ad mission, the patient's general condition deteriorated abruptly, with the onset of drowsiness and psychomotor ret...
Source: Clinical Case Reports - September 4, 2023 Category: General Medicine Authors: Alpha Oumar Diallo,
Amelie Marcou,
J érémie Lespinasse,
Zaida Cordoba‐Sosa,
Emmanuel Andrès,
Léa Docquier,
Noel Lorenzo‐Villalba Tags: CASE REPORT Source Type: research
Interpreting the Coronary Artery Calcium Score - Critical Information for the Practicing Physician
Am J Med. 2023 Sep 1:S0002-9343(23)00537-5. doi: 10.1016/j.amjmed.2023.08.005. Online ahead of print.ABSTRACTCoronary artery calcium (CAC) scanning is a routine test for assessing the severity of atherosclerosis in asymptomatic individuals. This inexpensive, non-invasive test quantifies the calcium deposition in the four principal coronary arteries. Correct interpretation is important to the physician (for recommending therapy) and to the patient (for determining his/her lifetime risk of a cardiovascular event). A score of zero indicates that a cardiovascular event is extremely unlikely in the next five years. In contrast,...
Source: Atherosclerosis - September 3, 2023 Category: Cardiology Authors: David S Schade Martin Hickey R Philip Eaton Source Type: research
Is coronary artery calcium an independent risk factor for white matter hyperintensity?
CONCLUSION: In elderly adults, the presence and severity of CAC is related to an increase in WMH volume. Our findings suggest an association between two different vascular bed diseases in addition to traditional vascular risk factors, possibly indicating a comorbid mechanism.PMID:37648961 | DOI:10.1186/s12883-023-03364-7
Source: Atherosclerosis - August 30, 2023 Category: Cardiology Authors: Hui Jin Xue Qin Fanfan Zhao Yuting Yan Yu Meng Zhenyu Shu Xiangyang Gong Source Type: research
Biomineralization of calcium phosphates functionalized with hydroxyapatite-binding peptide
J Mech Behav Biomed Mater. 2023 Aug 22;146:106082. doi: 10.1016/j.jmbbm.2023.106082. Online ahead of print.ABSTRACTFunctionalization of calcium phosphates with biomimetic peptides is a promising strategy to increase cellular response for bone tissue repair. In this work, biphasic calcium phosphate pellets were functionalized with the hydroxyapatite-binding peptide pVTK by dropping a suspension of the peptide on the pellet surface. The bioactivity tests were performed in vitro by using McCoy culture medium. Cytotoxicity tests were also performed to assess cell viability. The material was characterized by X-ray diffraction (...
Source: Journal of the Mechanical Behavior of Biomedical Materials - August 24, 2023 Category: Materials Science Authors: Marvin do Nascimento Aline Raybolt Dos Santos Almeida Mariah Cationi Hirata Amal Elzubair Daniel Navarro da Rocha Marcelo Henrique Prado da Silva Source Type: research
Identification of strontium substitution mechanism in hematite via calcium solution
This study confirms the substitution of Sr with Ca, highlighting the physicochemical similarity of the Sr and Ca that facilitates substitution reactions.PMID:37619756 | DOI:10.1016/j.chemosphere.2023.139925
Source: Chemosphere - August 24, 2023 Category: Chemistry Authors: Hojae Song Seulki Jeong Kyoungphile Nam Source Type: research
