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Total 1057 results found since Jan 2013.

Enhanced mechanical and functional properties of chitosan/polyvinyl alcohol/hydroxypropyl methylcellulose/alizarin composite film by incorporating cinnamon essential oil and tea polyphenols
In this study, cinnamon essential oil and tea polyphenols were added to chitosan/ polyvinyl alcohol/ hydroxypropyl methylcellulose/ alizarin composite films to enhance their mechanical and functional properties. Their addition to the composite films enhanced their antibacterial and antioxidant properties and significantly improved its elongation at break (p < 0.05). Cinnamon essential oil reduced the water vapor permeability, water content, and water solubility of composite films and improved their transparency. The composite films with additive exhibited excellent UV-barrier ability and pH responsivity. Fourier Transfo...
Source: International Journal of Biological Macromolecules - September 15, 2023 Category: Biochemistry Authors: Hongpeng Yu Qing Zhou Dong He JinJin Yang Kegang Wu Xianghua Chai Yujuan Xiang Xuejuan Duan Xiqin Wu Source Type: research

Fight Aging! Newsletter, September 11th 2023
This article reviews the current regulatory role of miR-7 in inflammation and related diseases, including viral infection, autoimmune hepatitis, inflammatory bowel disease, and encephalitis. It expounds on the molecular mechanism by which miR-7 regulates the occurrence of inflammatory diseases. Finally, the existing problems and future development directions of miR-7-based intervention on inflammation and related diseases are discussed to provide new references and help strengthen the understanding of the pathogenesis of inflammation and related diseases, as well as the development of new strategies for clinical interventi...
Source: Fight Aging! - September 10, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Synthesis, biological and molecular docking studies of pyrimidine-derived bioactive Schiff bases
Bioorg Chem. 2023 Sep 1;140:106822. doi: 10.1016/j.bioorg.2023.106822. Online ahead of print.ABSTRACTPyrimidine which is an important constituent of the genetic material of deoxyribonucleic acid, is identified with a large number of biological activities. Based on this, pyrimidine-derived Schiff bases (1-6) of hydroxy-1-naphthaldehyde were synthesized by using the condensation method. In addition, the molecular docking studies against topoisomerase II DNA gyrase, human hematopoietic cell kinase, urate oxidase from Aspergillus flavus, and cyclin-dependent kinase 8 to explore the antibacterial, antioxidant, antifungal, and a...
Source: Bioorganic Chemistry - September 4, 2023 Category: Chemistry Authors: Saira Manzoor Rana Adnan Tahir Muhammad Adnan Younis Wen-Li Cao Qamar-Un-Nisa Tariq Amjad Ali Naushad Ahmad Chuntian Qiu Bingbing Tian Jian-Guo Zhang Source Type: research

Extraction and characterization of Chitosan from Shell of Borassus flabellifer and their antibacterial and antioxidant applications
This study aimed to investigate the biological activity of chitosan extracted from B. flabellifer fruit shells and to analyze its molecular structure using FT-IR analysis. Results showed the presence of NH, OH, and CO stretching, indicating the presence of various functional groups in chitosan. Scanning electron microscopic study revealed the topography of the chitosan. Well-diffusion and MIC tests showed that chitosan exhibited activity against E. coli and S. aureus. The chitosan extract also exhibited potential antioxidant polymer by scavenging free radicals.PMID:37659486 | DOI:10.1016/j.ijbiomac.2023.126592
Source: International Journal of Biological Macromolecules - September 2, 2023 Category: Biochemistry Authors: Vishwapriya Saravanan MubarakAli Davoodbasha Arjun Rajesh Thajuddin Nooruddin Sang-Yul Lee Jung-Wan Kim Source Type: research

Exploring the Therapeutic Properties of Alga-Based Silver Nanoparticles: Anticancer, Antibacterial, and Free Radical Scavenging Capabilities
In conclusion, our biosynthesized AgNPs from the algae Spirulina Platensis can be potent antioxidant, anticancer and antibacterial activities.PMID:37647307 | DOI:10.1002/cbdv.202301068
Source: Chemistry and Biodiversity - August 30, 2023 Category: Biochemistry Authors: Amir Hamza Khan Khan Said Hassan Muhammad Aamir Muhammad Waseem Khan Fazal Haq Junaid Hayat Muhammad Rizwan Amin Ullah Izzat Ullah Gokhan Zengin Arshad Farid Source Type: research

Fight Aging! Newsletter, August 14th 2023
This study demonstrates just how vital the thymus is to maintaining adult health." « Back to Top Does Amyloid-β Aggregation Cause Broad Disruption of Proteostasis? https://www.fightaging.org/archives/2023/08/does-amyloid-%ce%b2-aggregation-cause-broad-disruption-of-proteostasis/ Researchers here speculate on the ability of insoluble amyloid-β aggregates to be broadly disruptive of the solubility of many other proteins, and thus disruptive to cell and tissue function. Is this important in aging? The evidence here shows the existence of the mechanism in a lower species, but that doesn't n...
Source: Fight Aging! - August 13, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Sarcococca saligna fabricated gold nanoparticles alleviated in vitro oxidative stress and inflammation in human adipose-derived stem cells
This study was carried out to evaluate the anti-inflammatory and antioxidant potential of bio fabricated GNPs with Sarcococca saligna (S. saligna) extract on injured human adipose-derived Mesenchymal stem cells (hADMSCs). GNPs were characterized by ultraviolet-visible (UV-Vis) spectroscopy, Scanning Electron Microscopy (SEM), x-ray diffraction (XRD), Fourier transform infrared spectroscopy (FTIR), and energy dispersive x-ray (EDS). Phytochemical screening of biosynthesized GNPs exhibited a significant release of polyphenols, that is, total phenolic content (TPC) and total flavonoid content (TFC). GNPs priming amended the i...
Source: Cell Research - August 10, 2023 Category: Cytology Authors: Nadia Naseer Muhammad Munam Mustafa Noreen Latief Numan Fazal Muhammad Tariq Afshan Afreen Faiza Yaqub Sheikh Riazuddin Source Type: research

Fight Aging! Newsletter, August 7th 2023
In conclusion, here, we demonstrate a novel mechanism for ESC-EVs to protect cells from senescence. However, whether ESC-EVs rejuvenate aged mice via miR-15b-5p and miR-290a-5p remains unknown. Next, we plan to use miR-15b-5p and miR-290a-5p antagonists while treating aged mice with ESC-EVs to further investigate the mechanism by which ESC-EVs resist aging in vivo. « Back to Top Fatty Acid Metabolism as a Commonality in Different Approaches to Slowing Aging https://www.fightaging.org/archives/2023/08/fatty-acid-metabolism-as-a-commonality-in-different-approaches-to-slowing-aging/ It seems...
Source: Fight Aging! - August 6, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Alginate-based edible coating with oregano essential oil/ β-cyclodextrin inclusion complex for chicken breast preservation
Int J Biol Macromol. 2023 Aug 2:126126. doi: 10.1016/j.ijbiomac.2023.126126. Online ahead of print.ABSTRACTA sodium alginate (SA) edible coating containing oregano essential oil (OEO)/β-cyclodextrin (β-CD) inclusion complexes (SA/OEO-MP coating) was developed to extend the shelf life of fresh chicken breast during refrigeration storage. First, OEO was inserted into the hydrophobic interior of β-CD to form an inclusion complex (OEO-MP) that maintained its excellent antioxidant and antibacterial activities. The formed OEO-MP was characterized using Fourier transform ion cyclotron resonance (FTIR), X-ray diffraction (XRD),...
Source: International Journal of Biological Macromolecules - August 4, 2023 Category: Biochemistry Authors: Xiaoxi Yang Dongxue Zhao Shaohui Ge Pengsha Bian Hongmei Xue Yumiao Lang Source Type: research

An in vitro and in vivo study: Valencene protects cartilage and alleviates the progression of osteoarthritis by anti-oxidative stress and anti-inflammatory effects
CONCLUSION: Our study demonstrated that VA is an effective candidate for OA treatment.PMID:37536183 | DOI:10.1016/j.intimp.2023.110726
Source: International Immunopharmacology - August 3, 2023 Category: Allergy & Immunology Authors: Sheng Chen Chen Meng Yi He Hanqing Xu Yunkun Qu Yingguang Wang Yunhui Fan Xiaojian Huang Hongbo You Source Type: research

Deciphering the anticancer, anti-inflammatory and antioxidant potential of Ti nanoparticles fabricated using Zingiber officinale
Environ Res. 2023 Jul 25:116748. doi: 10.1016/j.envres.2023.116748. Online ahead of print.ABSTRACTRapid and sustainable green technology was implemented in the current study to fabricate Ti nanoparticles. The vegetable ginger with the scientific name Zingiber officinale was employed as a biological source in the fabrication process of nanoparticles. The optical, structural, morphological, and particle size of the fabricated Ti nanoparticles were characterized with the help of UV-visible absorption spectrum, FTIR (Fourier Transform Infrared) spectrum, SEM (Scanning Electron Microscope) analysis, DLS (Dynamic Light Scatterin...
Source: Environmental Research - July 27, 2023 Category: Environmental Health Authors: Nguyen Thi Anh Nga Selvam Sathiyavimal Latifah A Al-Humaid Nora Dahmash Al-Dahmash Jintae Lee Selvaraj Barathi G K Jhanani Source Type: research