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Management: Mergers and Aquisitions
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Total 416 results found since Jan 2013.
CD4+CD8+ T-Lymphocytes in Xenogeneic and Human Graft-versus-Host Disease
Mechanisms driving acute graft-versus-host disease (aGVHD) onset in patients undergoing allogeneic hematopoietic stem cell transplantation (allo-HSCT) are still poorly understood. To provide a detailed characterization of tissue-infiltrating T lymphocytes (TL) and search for eventual site-specific specificities, we developed a xenogeneic model of aGVHD in immunodeficient mice. Phenotypic characterization of xenoreactive T lymphocytes (TL) in diseased mice disclosed a massive infiltration of GVHD target organs by an original CD4+CD8+ TL subset. Immunophenotypic and transcriptional profiling shows that CD4+CD8+ TL comprise a...
Source: Frontiers in Immunology - November 24, 2020 Category: Allergy & Immunology Source Type: research
A physician moves from the exam room to the C-suite PODCAST
“The dictionary definition of learning is‘the acquisition of knowledge or skills through experience, study, or by being taught.’ For leaders, the most crucial and common way of learning happens through experience, and as we often say, leadership is flying the plane while building it. Moreover, the onus of making the process of learning an […]Find jobs at Careers by KevinMD.com. Search thousands of physician, PA, NP, and CRNA jobs now. Learn more.
Source: Kevin, M.D. - Medical Weblog - November 29, 2020 Category: General Medicine Authors: < span itemprop="author" > < a href="https://www.kevinmd.com/blog/post-author/the-podcast-by-kevinmd" rel="tag" > The Podcast by KevinMD < /a > < /span > Tags: Podcast Practice Management Source Type: blogs
Kyruus and HealthSparq Come Together to Transform Care Navigation Through Novel Payer-Provider Collaboration
Kyruus, the leader in provider search and scheduling solutions for health systems, and HealthSparq, a trailblazing healthcare guidance and transparency technology company serving health plans, today announced they are joining forces to lead the next wave of transformation around how people navigate healthcare. HealthSparq will become part of Kyruus, accelerating a groundbreaking platform to connect payer […]
Source: EMR and HIPAA - December 20, 2020 Category: Information Technology Authors: Healthcare IT News Tags: Health IT Company Healthcare IT Cambia Health Solutions Graham Gardner Health IT Acquisitions Health Plans HealthSparq Kyruus Kyruus ProviderMatch Mark Menton Source Type: blogs
Dentulu Closes $2.5 Million Seed Fund Round for Aggressive Development of Its Global Teledentistry Platform
Acquires Robohealer AI, Adding Artificial Intelligence Capabilities to Its Software Platform and Announces Expansion of the Dentulu Strategic Partner Network Los Angeles, CA; April 12, 2021– Dentulu announces the closing of an initial seed round investment of $2.5M as well as the acquisition of Robohealer AI. Robohealer, is a dynamic interactive symptom screener which uses artificial intelligence to make teleconsultations and care recommendations easy for patients and efficient for dentists.“Dentulu’s mission is to increase direct access to dental care for billions of people worldwide,” said Dentul...
Source: Dental Technology Blog - April 13, 2021 Category: Dentistry Source Type: news
The risk of mortality in patients with COVID-19 with pre-diagnosis use of NSAIDs: a meta-analysis
AbstractThe notion that the use of non-steroidal anti-inflammatory drugs (NSAIDs) may lead to adverse outcomes upon acquisition of coronavirus disease 2019 (COVID-19) should be discredited with a review of the real-life evidence. We aimed to perform a meta-analysis to summarize the risk of mortality with the preadmission/pre-diagnosis use of NSAIDs in patients with COVID-19. A systematic literature search was performed to identify eligible studies in electronic databases. The outcome of interest was the development of a fatal course of COVID-19. Adjusted hazard ratio or odds ratio/relative risk and the corresponding 95% co...
Source: Inflammopharmacology - April 21, 2021 Category: Drugs & Pharmacology Source Type: research
60Fe and 244Pu deposited on Earth constrain the r-process yields of recent nearby supernovae
Half of the chemical elements heavier than iron are produced by the rapid neutron capture process (r-process). The sites and yields of this process are disputed, with candidates including some types of supernovae (SNe) and mergers of neutron stars. We search for two isotopic signatures in a sample of Pacific Ocean crust—iron-60 (60Fe) (half-life, 2.6 million years), which is predominantly produced in massive stars and ejected in supernova explosions, and plutonium-244 (244Pu) (half-life, 80.6 million years), which is produced solely in r-process events. We detect two distinct influxes of 60Fe to Earth in the last 10 ...
Source: Science: Current Issue - May 13, 2021 Category: Science Authors: Wallner, A., Froehlich, M. B., Hotchkis, M. A. C., Kinoshita, N., Paul, M., Martschini, M., Pavetich, S., Tims, S. G., Kivel, N., Schumann, D., Honda, M., Matsuzaki, H., Yamagata, T. Tags: Astronomy, Geochemistry, Geophysics, Physics reports Source Type: research
Cardiac arrest
I was watching the Euro 2020 game between Denmark and Finland, I am sure encouraged by the presence of a Norwich City player on one side and a Leicester City one on the other. I did not see Christian Eriksen fall but I watched as his teammates formed a barrier round him, and perhaps saw too much as the television companies made a decision what to do.I was, along with everyone, so pleased that the prompt treatment given to Christian Eriksen brought him back and that he is now recovering.It was a cardiac arrest - not the same thing as a heart attack - and theBritish Heart Foundation have a useful page about what ...
Source: Browsing - June 17, 2021 Category: Databases & Libraries Tags: cardiac arrest defibrillators Source Type: blogs
ChimST: An Efficient Spectral Library Search Tool for Peptide Identification from Chimeric Spectra in Data-Dependent Acquisition
Source: IEEE/ACM Transactions on Computational Biology and Bioinformatics - August 6, 2021 Category: Bioinformatics Source Type: research
The FTC ’s Absurd Attempts At Defining Facebook’s Product Market
Ryan BourneWhen it comes to Facebook, antitrust authorities are making it up as they go along. The company is extremely big, and so necessarily “bad” in the eyes of today’sneo-Brandeisian trustbusting movement, one member of whom, Lina Khan, now chairs the Federal Trade Commission. These people just know that Facebook is a monopolist using its market power anticompetitively, and so see the task of their agencies to define the market to first prove that Facebook meets the conditions necessary for antitrust action against them.Back in late June, the U.S. District Court in DC threw out a complaint by the FTC against Fac...
Source: Cato-at-liberty - August 20, 2021 Category: American Health Authors: Ryan Bourne Source Type: blogs
Niwaki Instead of Random Forests: Targeted Serial Sectioning Scanning Electron Microscopy With Reimaging Capabilities for Exploring Central Nervous System Cell Biology and Pathology
Ultrastructural analysis of discrete neurobiological structures by volume scanning electron microscopy (SEM) often constitutes a “needle-in-the-haystack” problem and therefore relies on sophisticated search strategies. The appropriate SEM approach for a given relocation task not only depends on the desired final image quality but also on the complexity and required accuracy of the screening process. Block-face SEM techniques like Focused Ion Beam or serial block-face SEM are “one-shot” imaging runs by nature and, thus, require precise relocation prior to acquisition. In contrast, “multi-shot” approaches conserv...
Source: Frontiers in Neuroanatomy - October 13, 2021 Category: Neurology Source Type: research
Molecules, Vol. 26, Pages 6362: Applying Active Learning to the Screening of Molecular Oxygen Evolution Catalysts
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The oxygen evolution reaction (OER) can enable green hydrogen production; however, the state-of-the-art catalysts for this reaction are composed of prohibitively expensive materials. In addition, cheap catalysts have associated overpotentials that render the reaction inefficient. This impels the search to discover novel catalysts for this reaction computationally. In this communication, we present machine learning algorithms to enhance the hypothetical screening of molecular OER catalysts. By predicting calculated binding energies using Gaussian process regression (GPR) models and applying active learning schemes, w...
Source: Molecules - October 21, 2021 Category: Chemistry Authors: Michael John Craig Max Garc ía-Melchor Tags: Communication Source Type: research
Molecules, Vol. 26, Pages 7354: The Anthelmintic Quassinoids Ailanthone and Bruceine a Induce Infertility in the Model Organism Caenorhabditis elegans by an Apoptosis-like Mechanism Induced in Gonadal and Spermathecal Tissues
an Herrmann
In continuation of the search for new anthelmintic natural products, the study at hand investigated the nematicidal effects of the two naturally occurring quassinoids ailanthone and bruceine A against the reproductive system of the model nematode Caenorhabditis elegans to pinpoint their anthelmintic mode of action by the application of various microscopic techniques. Differential Interference Contrast (DIC) and the epifluorescence microscopy experiments used in the presented study indicated the genotoxic effects of the tested quassinoids (c ailanthone = 50 &micro;M, c bruceine A = 100 &micro...
Source: Molecules - December 3, 2021 Category: Chemistry Authors: Nicola Knetzger Viktoria Bachtin Susanne Lehmann Andreas Hensel Eva Liebau Fabian Herrmann Tags: Article Source Type: research
Vitamin D and COVID-19: where are we now?
The objective of this study was to carry out a review of the current data that associate vitamin D status with the acquisition, evolution, and/or severity of infection by the SARS-CoV-2 virus and to assess whether prevention through vitamin D supplementation can prevent infection and/or improve the evolution once acquired. Vitamin D system has an immunomodulatory function and plays a significant role in various bacterial and viral infections. The immune function of vitamin D is explained in part by the presence of its receptor (VDR) and its activating enzyme 25-hydroxyvitamin D-1alpha-hydroxylase (CYP27B1) in immune cells....
Source: Postgraduate Medicine - December 10, 2021 Category: Internal Medicine Authors: Victoria Contreras-Bol ívar Beatriz Garc ía-Fontana Cristina Garc ía-Fontana Manuel Mu ñoz-Torres Source Type: research
