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Fight Aging! Newsletter, July 31st 2023
In conclusion, an SBP level below 130 mmHg was found to be associated with longevity among older women. The longer SBP was controlled at a level between 110 and 130 mmHg, the higher the survival probability to age 90. Preventing age-related rises in SBP and increasing the time with controlled BP levels constitute important measures for achieving longevity. « Back to Top
Source: Fight Aging! - July 30, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

The Macro View – Health, Economics, and Politics and the Big Picture. What I Am Watching Here And Abroad.
September 15, 2022 Edition-----The death of QE2 has rather dominated the news for the last week or so and will probably pass after the funeral today.Otherwise the war in Ukraine seems to be in a turning phase. I hope that continues into the eventual getting rid of the Russians from Ukrainian territory!In OZ life goes on much as usual just awaiting the mourning period to pass,-----Major Issues.-----https://www.afr.com/policy/foreign-affairs/what-australia-should-do-about-taiwan-20220904-p5bf7iWhat Australia should do about TaiwanCanberra cannot be silent if US policy on Taiwanese independence changes. Quiet diplomacy is cal...
Source: Australian Health Information Technology - September 15, 2022 Category: Information Technology Authors: Dr David G More MB PhD Source Type: blogs

How We Wrested Control of Our Rx Drug Spending. Maybe You Can, too.
This week, we ' ve heard reporting that the big Congressional bill which was supposed to include a provision for Medicare, which is the taxpayer-funded senior insurance plan to actually negotiate prices on prescription drugs (just as most other countries, as well as the Veteran ' s Administration [VA] already do right now) was going to be omitted because of a handful of PhRMA-bankrolled lawmakers pushed to kill it. That said, it isn ' t over until its over. Although we don ' t know what she might or might not do, House Majority Leader Nancy Pelosi still has some tricks in her own playbook if it doesn ' t happen a...
Source: Scott's Web Log - November 1, 2021 Category: Endocrinology Tags: coupon-generating websites apps PBM prescriptions Source Type: blogs

7 Futuristic Professions In Healthcare You Can Still Prepare For
If you’re among the thousands of medical students worldwide or are about to pursue a degree in healthcare, it might have dawned on you that the field wouldn’t look the same by the time you get into clinical practice. With drones delivering medical supplies; an ever-increasing wealth of data from personal health sensors; and patients turning to telemedicine, the medical workplace will decidedly look different by then.  But you also regularly hear news like how algorithms are able to beat radiologists to the punch when identifying cancerous lesions in medical images. These can fuel fear that such advanced tec...
Source: The Medical Futurist - May 11, 2021 Category: Information Technology Authors: Pranavsingh Dhunnoo Tags: Lifestyle medicine 3D Printing Artificial Intelligence in Medicine Digital Health Research E-Patients Future of Medicine Healthcare Design Medical Education Portable Medical Diagnostics Robotics Science Fiction Security & Privacy T Source Type: blogs

Fight Aging! Newsletter, January 25th 2021
In conclusion, our studies highlight the important role of the tyrosine degradation pathway and position TAT as a link between neuromediator production, dysfunctional mitochondria, and aging.
Source: Fight Aging! - January 24, 2021 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

DARZALEX FASPRO ® (daratumumab and hyaluronidase-fihj) Becomes the First FDA-Approved Treatment for Patients with Newly Diagnosed Light Chain (AL) Amyloidosis
January 15, 2021 (HORSHAM, Pa.) – The Janssen Pharmaceutical Companies of Johnson & Johnson announced today the U.S. Food and Drug Administration (FDA) approval of DARZALEX FASPRO® (daratumumab and hyaluronidase-fihj), a subcutaneous formulation of daratumumab, in combination with bortezomib, cyclophosphamide and dexamethasone (D-VCd) for the treatment of adult patients with newly diagnosed light chain (AL) amyloidosis.[1] DARZALEX FASPRO® is the first and only FDA-approved treatment for patients with this blood cell disorder that is associated with the production of an abnormal protein, which leads to the deterior...
Source: Johnson and Johnson - January 16, 2021 Category: Pharmaceuticals Tags: Our Company Source Type: news

Prevalence and Patterns of Opioid Use Before and After Liver Transplantation
Conclusions. Prescription opioid use is common before and after liver transplant, with intermittent and chronic use largely persisting, and a small development of new chronic use posttransplant. To minimize the morbidity of long-term opioid use, it is critical to improve pain management and optimize opioid use before and after liver transplant.
Source: Transplantation - December 24, 2020 Category: Transplant Surgery Tags: Original Clinical Science—Liver Source Type: research

Outcomes of Palliative Care Services Embedded in a Hepatology Clinic at a Large Public Hospital (S773)
Patients with end-stage liver disease (ESLD) in safety-net systems are often ineligible for liver transplantation due to immigration status, lack of insurance, inadequate social support, or active substance misuse. These patients facing terminal illness would benefit from the symptom management, intensive psychosocial support, and advance care planning (ACP) that palliative care (PC) offers. In collaboration with the hepatology department, we embedded PC services in the hepatology clinic of a large safety-net hospital.
Source: Journal of Pain and Symptom Management - January 25, 2020 Category: Palliative Care Authors: Carin van Zyl, Aaron Storms, Welmoed Van Deen, Alicia Flores, Robin Ellis, Lily Chu, Tanu Patel, Michael Hochman, John Donovan Source Type: research

He ’s the First African American to Receive a Face Transplant. His Story Could Change Health Care
Robert Chelsea turned down the first face he was offered. It was a fine face, one that could have taken him off the transplant waiting list after just a couple months. But Chelsea—severely disfigured after a catastrophic car accident five years earlier—was in no hurry. He’d gotten used to tilting his head back so food and water wouldn’t fall out of his nearly lipless mouth. He knew how to respond compassionately to children who stared in shock and fear. The face, offered in May 2018, had belonged to a man with skin that was much fairer than what remained of Chelsea’s—so light that Chelse...
Source: TIME: Health - October 24, 2019 Category: Consumer Health News Authors: Jamie Ducharme Tags: Uncategorized Healthcare Source Type: news

Should I participate in a cardiac rehabilitation program?
Cardiac rehabilitation (CR), or “cardiac rehab,” is a multifaceted, medically supervised program proven to improve heart health and outcomes in people with certain types of cardiovascular disease. CR revolves around three major components: an individualized exercise and training program, education on topics related to heart health, and stress reduction. CR is currently recommended for the following diagnoses: angina (chest pain); heart attack with or without angioplasty or bypass surgery; heart failure with reduced ejection fraction (HFrEF); and heart surgery including heart valve procedures or heart or heart/lung tran...
Source: Harvard Health Blog - October 10, 2019 Category: Consumer Health News Authors: Hicham Skali, MD, MSc, FACC Tags: Exercise and Fitness Health Heart Health Source Type: blogs

Fight Aging! Newsletter, August 12th 2019
We examined 9293 individuals from the Copenhagen General Population Study using nuclear magnetic resonance spectroscopy measurements of total cholesterol, free- and esterified cholesterol, triglycerides, phospholipids, and particle concentration. Fourteen subclasses of decreasing size and their lipid constituents were analysed: six subclasses were very low-density lipoprotein (VLDL), one intermediate-density lipoprotein (IDL), three low-density lipoprotein (LDL), and four subclasses were high-density lipoprotein (HDL). Remnant lipoproteins were VLDL and IDL combined. Mean nonfasting cholesterol concentration was 72�...
Source: Fight Aging! - August 11, 2019 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

What Infectious Diseases are Important to Consider in Transplantation Patients?
Discussion Transplantation is not a common problem for primary care physicians but when a child’s disease has progressed to end-stage organ failure, transplantation can be the only treatment available. While the primary care provider usually is not involved in the daily management of patients before, during and after transplantation, they can be involved in many areas. These can include providing appropriate primary and acute care, ordering and obtaining necessary medical tests, medications and equipment, assisting with medical insurance, providing medical history and records to consultants, translating medical infor...
Source: PediatricEducation.org - June 24, 2019 Category: Pediatrics Authors: pediatriceducationmin Tags: Uncategorized Source Type: news

Employers Are Steering Workers Toward Controversial Stem Cell Therapies
A Midwestern grocery chain, Hy-Vee, is taking an unusual—and highly controversial—approach to reducing health care costs. Before employees in certain cities can undergo knee replacement, they first must visit a stem cell provider. Hy-Vee has contracted with one of the U.S.’ leading stem cell companies—Regenexx, based in Des Moines, Iowa—that claims injections of concentrated bone marrow or platelets can help patients avoid expensive joint surgery. Regenexx has persuaded over 100 employers to include its services in their health insurance plans. In a marketing booklet, Regenexx, whose injection...
Source: TIME: Health - June 19, 2019 Category: Consumer Health News Authors: Liz Szabo / Kaiser Health News Tags: Uncategorized Healthcare medicine Source Type: news

Current Clinical Trials in Pemphigus and Pemphigoid
Conclusions The clinical trials discussed here, which include several trials investigating novel therapeutic targets, demonstrate that translational research in pemphigus and pemphigoid is a fast-growing field. We thus expect that several novel treatments will be shortly available for the treatment of pemphigus and pemphigoid patients. Given the high, and thus far unmet, medical need in this field (110), this is highly encouraging and will hopefully improve the quality of life of the affected patients. In addition to the compounds and targets described here, several new targets have been recently identified in preclinical...
Source: Frontiers in Immunology - May 2, 2019 Category: Allergy & Immunology Source Type: research

Prognosis after Upfront Radiation Therapy in Plasma Cell Myeloma: Analysis of the National Cancer Data Base
ConclusionsIn this large nationwide cohort, nearly 1 in 5 of newly diagnosed myeloma patients received upfront RT. The association between socio-economic variables like income or insurance status and the use of upfront RT suggests that a delay in diagnosis may lead to severe skeletal complications of myeloma requiring RT. Worse survival with upfront RT may similarly correspond to more advanced disease, but persistent association in sensitivity analyses supports the hypothesis that a presentation with skeletal complications reflects a more aggressive myeloma biology. Further research should aim at disentangling the socio-ec...
Source: Blood - November 21, 2018 Category: Hematology Authors: Orcutt, X., Barth, P., Olszewski, A. J. Tags: 653. Myeloma: Therapy, excluding Transplantation: Poster II Source Type: research

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