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Case report: Rapid improvement of crossed cerebellar diaschisis after intravascular laser irradiation of blood in a case of stroke
Rationale: Crossed cerebellar diaschisis (CCD) is a poor prognostic factor after stroke because without immediate cerebral reperfusion no further improvements in the patient's condition can be achieved. We investigated the clinical effects of intravascular laser irradiation therapy (ILIB) on CCD and evaluated the therapeutic effect in the sub-acute post-stroke stage. Patient concerns: The 77-year-old male with cerebral infarction in the territory of the right anterior cerebral artery only underwent conservative treatment including hydration and aspirin in the acute post-stroke stage. Diagnosis: He was diagnosed as stroke...
Source: Medicine - January 1, 2017 Category: Internal Medicine Tags: Research Article: Clinical Case Report Source Type: research

Late Seizures after Stroke in Clinical Practice: The Prevalence of Non-convulsive Seizures.
Conclusion There was a high rate of non-convulsive seizures in patients with late seizure after stroke. A non-convulsive seizure may be caused by any type or location of preceding stroke. More attention is needed in the differential diagnosis of neurological deterioration after stroke. PMID: 28321060 [PubMed - in process]
Source: Internal Medicine - March 23, 2017 Category: Internal Medicine Tags: Intern Med Source Type: research

The benefits of clinical facilitators on improving stroke care in acute hospitals: a new program for Australia
ConclusionFixed‐term employment of Facilitators was effective in positively influencing stroke care in hospitals through a range of change management strategies where stroke‐specific expertise had been previously limited.
Source: Internal Medicine Journal - April 19, 2017 Category: Internal Medicine Authors: Tara Purvis, Karen Moss, Linda Francis, Karen Borschmann, Monique F. Kilkenny, Sonia Denisenko, Christopher F. Bladin, Dominique A. Cadilhac Tags: Original Article Source Type: research

Stroke rates vary substantially across cohorts of patients with atrial fibrillation
Commentary on: Quinn GRSeverdija ONChang Y. Wide variation in reported rates of stroke across cohorts of patients with atrial fibrillation. Circulation 2017;135:208–19. Context Oral anticoagulants (OACs) substantially reduce stroke risk in patients with atrial fibrillation (AF); however, they remain globally underused.1 One of the main reasons is the difficulty in stratifying AF-related ischaemic stroke risk at the individual patient level.1 2 Among scores stratifying AF-related stroke risk, CHA2-DS2-Vasc prevails in most recent international AF guidelines.3 4 Still, it remains unknown whether AF-related stroke risk ...
Source: Evidence-Based Medicine - June 9, 2017 Category: Internal Medicine Authors: Sposato, L. A., Saposnik, G. Tags: EBM Prognosis Source Type: research

Benefits of clinical facilitators on improving stroke care in acute hospitals: a new programme for Australia
ConclusionFixed‐term employment of Facilitators was effective in positively influencing stroke care in hospitals through a range of change management strategies where stroke‐specific expertise had been previously limited.
Source: Internal Medicine Journal - July 4, 2017 Category: Internal Medicine Authors: Tara Purvis, Karen Moss, Linda Francis, Karen Borschmann, Monique F. Kilkenny, Sonia Denisenko, Christopher F. Bladin, Dominique A. Cadilhac Tags: Original Article Source Type: research

Association of ventricular arrhythmia and in-hospital mortality in stroke patients in Florida: A nonconcurrent prospective study
Abstract: Stroke remains one of the leading causes of death in the United States. Current evidence identified electrocardiographic abnormalities and cardiac arrhythmias in 50% of patients with an acute stroke. The purpose of this study was to assess whether the presence of ventricular arrhythmia (VA) in adult patients hospitalized in Florida with acute stroke increased the risk of in-hospital mortality. Secondary data analysis of 215,150 patients with ischemic and hemorrhagic stroke hospitalized in the state of Florida collected by the Florida Agency for Healthcare Administration from 2008 to 2012. The main outcome for th...
Source: Medicine - July 1, 2017 Category: Internal Medicine Tags: Research Article: Observational Study Source Type: research

Long ‐term use of Proton Pump Inhibitors, Dose‐response Relationship, and Associated Risk of Ischemic Stroke and Myocardial Infarction
ConclusionUse of PPIs was associated with increased risks of first‐time ischemic stroke and MI, particularly among long‐term users and at high doses.This article is protected by copyright. All rights reserved.
Source: Journal of Internal Medicine - October 1, 2017 Category: Internal Medicine Authors: Thomas S. G. Sehested, Thomas A. Gerds, Emil L. Fosb øl, Peter W. Hansen, Mette G. Charlot, Nicholas Carlson, Mark A. Hlatky, Christian Torp‐Pedersen, Gunnar H. Gislason Tags: Original Source Type: research

Long ‐term use of proton pump inhibitors, dose–response relationship and associated risk of ischemic stroke and myocardial infarction
ConclusionUse of PPIs was associated with increased risks of first‐time ischemic stroke and MI, particularly amongst long‐term users and at high doses.
Source: Journal of Internal Medicine - November 7, 2017 Category: Internal Medicine Authors: T. S. G. Sehested, T. A. Gerds, E. L. Fosb øl, P. W. Hansen, M. G. Charlot, N. Carlson, M. A. Hlatky, C. Torp‐Pedersen, G. H. Gislason Tags: Original Article Source Type: research

Therapeutic effect of Chinese herbal medicines for post stroke recovery: A traditional and network meta-analysis
Background: Stroke is a condition with high morbidity and mortality, and 75% of stroke survivors lose their ability to work. Stroke is a burden to the family and society. The purpose of this study was to evaluate the effectiveness of Chinese herbal patent medicines in the treatment of patients after the acute phase of a stroke. Methods: We searched the following databases through August 2016: PubMed, Embase, Cochrane library, China Knowledge Resource Integrated Database (CNKI), China Science Periodical Database (CSPD), and China Biology Medicine disc (CBMdisc) for studies that evaluated Chinese herbal patent medicines...
Source: Medicine - December 1, 2017 Category: Internal Medicine Tags: Research Article: Systematic Review and Meta-Analysis Source Type: research

Progression of diabetes, heart disease, and stroke multimorbidity in middle-aged women: A 20-year cohort study
ConclusionsStroke was associated with increased risk of progression to diabetes or heart disease. Social inequality, obesity, hypertension, physical inactivity, smoking, or having other chronic conditions were also significantly associated with increased odds of accumulating multimorbidity. Our findings highlight the importance of awareness of the role of diabetes, heart disease, and stroke multimorbidity among middle-aged women for clinicians and health-promotion agencies.
Source: PLoS Medicine - March 13, 2018 Category: Internal Medicine Authors: Xiaolin Xu Source Type: research

Herbal Medicine in Ischemic Stroke: Challenges and Prospective
AbstractHerbal medicines, mainly of plant source, are invaluable source for the discovery of new therapeutic agents for all sorts of human ailments. The complex pathogenesis of stroke and multifactorial effect of herbal medicine and their active constituents may suggest the promising future of natural medicine for stroke treatment. Anti-oxidant, anti-inflammatory, anti-apoptotic, neuroprotective and vascular protective effect of herbal medicines are believed to be efficacious in stroke treatment. Herbs typically have fewer reported side effects than allopathic medicine, and may be safer to use over longer period of time. H...
Source: Chinese Journal of Integrative Medicine - April 1, 2018 Category: Internal Medicine Source Type: research

Estimate of ischemic stroke prevalence according to a novel 4-tiered classification of left ventricular hypertrophy: Insights from the general Chinese population.
CONCLUSIONS: Indeterminate and thick hypertrophy were significantly associated with the presence of ischemic stroke in the general Chinese population. The new 4-tiered categorization of LVH can permit a better understanding of which subjects are at high enough risk for ischemic stroke to warrant early targeted therapy. PMID: 30001637 [PubMed - as supplied by publisher]
Source: Annals of Medicine - July 14, 2018 Category: Internal Medicine Tags: Ann Med Source Type: research

Comparison of recovery patterns of gait patterns according to the paralyzed side in Korean stroke patients: Protocol for a retrospective chart review
Conclusion: If the use of gait analysis systems (GAITRite, G-walk, and Treadmill) confirms differences in gait recovery pattern among stroke patients according to the paralyzed side, the findings will provide essential evidence for differential treatment of stroke patients on that basis.
Source: Medicine - August 1, 2018 Category: Internal Medicine Tags: Research Article: Study Protocol Clinical Trial Source Type: research

Adherence to the dietary approaches to stop hypertension diet and risk of stroke: A meta-analysis of prospective studies
The Dietary Approaches to Stop Hypertension (DASH) diet has been shown to lower the risk of hypertension, but its role in the prevention of stroke remains in debate. We therefore conducted a meta-analysis to examine the association between DASH diet and incident stroke. A systematic database search in PubMed and Embase was performed to identify eligible prospective studies. The study-specific relative risks (RRs) and 95% confidence intervals (CIs) were pooled using random-effect meta-analysis. Dose–response relationship between DASH diet score and risk of stroke was also assessed. We included 12 prospective cohort stud...
Source: Medicine - September 1, 2018 Category: Internal Medicine Tags: Research Article: Meta-Analysis of Observational Studies in Epidemiology Source Type: research

Matrix metalloproteinase-2 gene polymorphisms are associated with ischemic stroke in a Hainan population
This study investigated the relationship between MMP-2 and stroke risk in the Southern Chinese population. We evaluated single nucleotide polymorphisms (SNP) of MMP-2 in stroke patients in an association study using a case-control design. Six SNPs of MMP2 were selected and genotyped by Agena MassARRAY. SNPStats, Haploview was used to analyze genetic data. Two SNPs in the MMP-2 gene were significantly associated with stroke risk. For rs1132896 (C versus G allele), the C allele was significantly reduced stroke risk (OR = 0.56, 95% confidence intervals [95% CI] = 0.39–0.81, P = .002). The effect of the T alle...
Source: Medicine - September 1, 2018 Category: Internal Medicine Tags: Research Article: Observational Study Source Type: research