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Total 107 results found since Jan 2013.

Nationwide trends in emergency department utilisation for acute retinal ischaemia in the USA, 2011-2018
Conclusion Of the estimated 48 000 patients with TMVL or RAO annually in the USA, few are evaluated in the ED, and admission rates are less than for transient ischaemic attack or ischaemic stroke and are decreasing over time.
Source: British Journal of Ophthalmology - September 21, 2023 Category: Opthalmology Authors: Hamedani, A. G., De Lott, L. B., Willis, A. W. Tags: Original articles - Clinical science Source Type: research

Risk of Stroke, Myocardial Infarction, Deep Vein Thrombosis, Pulmonary Embolism, and Death after Retinal Vein Occlusion
To examine rates of stroke, myocardial infarction (MI), deep vein thrombosis (DVT), pulmonary embolism (PE), and death in patients after retinal vein occlusion (RVO) compared to controls.
Source: American Journal of Ophthalmology - September 1, 2023 Category: Opthalmology Authors: Karen M. Wai, Cassie A. Ludwig, Euna Koo, Ravi Parikh, Prithvi Mruthyunjaya, Ehsan Rahimy Tags: Original Articles Source Type: research

Pole to pole
An otherwise asymptomatic 67-year-old man presented to his ophthalmologist complaining of acute painless “dark area on the right”. Visual acuity was preserved and a single cotton-wool spot was noted in each retina. An inferior right quadrantanopia was evident on automated visual field and computerized tomography of the brain confirmed a left occipital stroke. Acute phase markers were elevated and t emporal artery biopsy was consistent with a diagnosis of giant cell arteritis. Isolated retinal cotton wool spots, even in the absence of systemic signs and symptoms, may be suggestive of giant cell arteritis.
Source: Survey of Ophthalmology - May 17, 2023 Category: Opthalmology Authors: Francesco Pellegrini, Maria Basciu, Julie Falardeau Source Type: research

Progressive Central Artery Occlusion, Ophthalmic Artery Occlusion, and Hemispheric Intracranial Thrombosis after COVID-19 mRNA Vaccine Application: Case Report
Thromboembolic events as a result of COVID-19 mRNA vaccination are a rare, though life-threatening complication. In this case report, we describe a 40-year-old female patient who developed central retinal artery and ophthalmic artery occlusion progressing to intracranial thrombosis 3 weeks after vaccination with the Pfizer-BioNTech COVID-19 vaccine. Initially, she presented with progressive acute and painless unilateral vision loss in her left eye. Dilated fundoscopy of left eye showed macular whitening with sparing of the area of cilioretinal artery distribution. Labs revealed a normal erythrocyte sedimentation rate, C-re...
Source: Case Reports in Ophthalmology - April 18, 2023 Category: Opthalmology Source Type: research

Risk and risk factor of ischemic stroke after acute retinal arterial ischemia
ConclusionPatients have a high risk of ischemic stroke, particularly those with a diagnosis of ICAS ( ≥ 70%) or occlusion after the onset of ARAI. Clinical management of ARAI should focus on vascular risk factors control and secondary prevention for stroke.
Source: International Ophthalmology - March 28, 2023 Category: Opthalmology Source Type: research

Ocular and systemic determinants of perifoveal and macular vessel parameters in healthy African Americans
Conclusions When interpreting OCTA images in a clinical setting, it is important to consider the effects ocular and systemic characteristics may have on the macular microcirculation.
Source: British Journal of Ophthalmology - March 22, 2023 Category: Opthalmology Authors: Richter, G. M., Lee, J. C., Khan, N., Vorperian, A., Hand, B., Burkemper, B., Zhou, X., Chu, Z., Wang, R., Varma, R., Kashani, A. H. Tags: Original articles - Clinical science Source Type: research

Artificial intelligence-enabled retinal vasculometry for prediction of circulatory mortality, myocardial infarction and stroke
Conclusion RV offers an alternative predictive biomarker to traditional risk-scores for vascular health, without the need for blood sampling or blood pressure measurement. Further work is needed to examine RV in population screening to triage individuals at high-risk.
Source: British Journal of Ophthalmology - November 22, 2022 Category: Opthalmology Authors: Rudnicka, A. R., Welikala, R., Barman, S., Foster, P. J., Luben, R., Hayat, S., Khaw, K.-T., Whincup, P., Strachan, D., Owen, C. G. Tags: Open access, Editor's choice, Press releases Original articles - Clinical science Source Type: research

Purtscher-Like Retinopathy with Cardioembolic Stroke: Case Report and Literature Review
We present a case of PUR associated with a cardioembolic stroke in a patient following temporary cessation of anticoagulant therapy for a surgical procedure. Our patient presented with multiple risk factors for PUR and classic signs and symptoms including multiple peripapillary white retinal lesions near arterioles and sudden unilateral decrease in visual acuity. Optical coherence tomography showed inner retinal hyperreflectivity and thinning consistent with inner retinal ischemia, and fluorescein angiography showed delayed retinal filling. Her complement C5 factor was elevated on laboratory testing. Brain magnetic resonan...
Source: Case Reports in Ophthalmology - November 17, 2022 Category: Opthalmology Source Type: research

Risk factors for ischemic cerebral stroke in patient with acute amaurosis fugax
CONCLUSION: Ischemic stroke and myocardial infarction were diagnosed in 0.3%-0.9% of hospitalized acute AF cases. Presence of hypercoagulable state, systemic vasculitis, CAD, and atherosclerosis each individually increased the risk of ischemic stroke by more than 3-fold; patients with these risk factors and acute AF should be closely monitored for developing acute systemic thrombotic events.PMID:36368408 | DOI:10.1016/j.jcjo.2022.10.010
Source: Canadian Journal of Ophthalmology - November 11, 2022 Category: Opthalmology Authors: Tony Y Chen Aditya Uppuluri Owais Aftab Marco Zarbin Nathan Agi Neelakshi Bhagat Source Type: research

Artificial intelligence-enabled retinal vasculometry for prediction of circulatory mortality, myocardial infarction and stroke
CONCLUSION: RV offers an alternative predictive biomarker to traditional risk-scores for vascular health, without the need for blood sampling or blood pressure measurement. Further work is needed to examine RV in population screening to triage individuals at high-risk.PMID:36195457 | DOI:10.1136/bjo-2022-321842
Source: The British Journal of Ophthalmology - October 4, 2022 Category: Opthalmology Authors: Alicja Regina Rudnicka Roshan Welikala Sarah Barman Paul J Foster Robert Luben Shabina Hayat Kay-Tee Khaw Peter Whincup David Strachan Christopher G Owen Source Type: research

Similarities and differences in systemic risk factors for retinal artery occlusion and retinal vein occlusion: A nationwide case –control study
ConclusionDifferences in the level of associations with the included risk factors suggests differences in the pathophysiologies of the two diseases. The main pathophysiology associated with RAO was atherosclerosis, whereas the main pathophysiology associated with RVO was changes in the pressure gradients of the eyes.
Source: International Ophthalmology - September 2, 2022 Category: Opthalmology Source Type: research

Role of the ABO blood groups as a risk factor for retinal vein occlusion
In this study we investigated (i) an association between blood group and the presence of RVO and (ii) whether this association correlated to other RVO risk factors. Methods We included 485 RVO patients and 295 control subjects who were recruited in this case-control study. We determined ABO genotypes rs8176719 as a marker for the O allele and rs8176746 for the B allele by polymerase chain reaction. Results We did not find an association between ABO blood gr oup and the presence of RVO. In detail, the proportion of ABO blood groups was similar among RVO patients and control subjects (p=0.527). In a logistic regression, ...
Source: Ophthalmic Research - September 1, 2022 Category: Opthalmology Source Type: research

Risks of posterior segment ocular ischaemic events in patients with systemic lupus erythematosus: a population-based cohort study in Taiwan
CONCLUSIONS: SLE increases the risk of developing OIE. Systemic comorbidities and higher dosage of steroid in patients with SLE are associated with severe ocular ischaemic complications.PMID:35922126 | DOI:10.1136/bjo-2022-321653
Source: The British Journal of Ophthalmology - August 3, 2022 Category: Opthalmology Authors: Yi-Ran Chiou Yu-Sheng Chang Chin-Fang Su Tzu-Hao Li Chien-Chih Lai De-Kuang Hwang Fang-Yi Wu Yu-Fan Chang Source Type: research