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Infectious Disease: Polio

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Total 35 results found since Jan 2013.

Central sleep apnea in a patient with dengue encephalitis
We report for the first time a case of Central sleep apnea in a patient with dengue encephalopathy. This is a case report of a 50 year old male who had presented with fever, body ache, headache and altered mental status. A diagnosis of dengue fever was made on the basis of IgM antibodies in serum and encephalopathy was attributed to dengue encephalitis in the absence of another etiological cause of encephalopathy. Persistent hyper somnolence and desaturation despite resolution of fever led to a polysomnographic evaluation, which revealed significant central sleep apnea. Hypersomnia, a primary complaint of excessive sleepin...
Source: Apollo Medicine - March 5, 2015 Category: Journals (General) Source Type: research

Correlates of a Single-Item Quality-of-Life Measure in People Aging with Disabilities.
CONCLUSION: The Kemp Quality of Life Scale relates significantly to clinically relevant variables in adults with impairments. The scale's utility in direct clinical care merits further examination.This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND), where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially. PMID: 25888654 [PubMed - as supplied by publisher]
Source: Physica Medica - April 16, 2015 Category: Physics Authors: Siebens HC, Tsukerman D, Adkins RH, Kahan J, Kemp B Tags: Am J Phys Med Rehabil Source Type: research

Correlates of a Single-Item Quality-of-Life Measure in People Aging with Disabilities
Objective: Practical quality-of-life (QOL) screening methods are needed to help focus clinical decision-making on what matters to individuals with disabilities. Design: A secondary analysis of a database from a large study of adults aging with impairments focused on four diagnostic groups: cerebral palsy (n = 134), polio (n = 321), rheumatoid arthritis (n = 99), and stroke (n = 82). Approximately 20% of cases were repeated measures of the same individuals 3–5 yrs later. Functional levels, depression, and social interactions were assessed. The single-item, subjective, seven-point Kemp Quality of Life Scale measured QOL. F...
Source: American Journal of Physical Medicine and Rehabilitation - November 22, 2015 Category: Rehabilitation Tags: Original Research Articles Source Type: research

Noah’s story: Enterovirus and a race against the clock
“I’m so excited to babyproof my house,” says Elisa Holt. “I haven’t had to. Now, Noah wants to climb and do all of these normal baby things.” The toddler, born in March 2014, sailed through his first six months of life. As summer turned to fall, enterovirus D68 (EV-D68), a mysterious virus linked with paralysis, started to dominate headlines. On Oct. 3, 2014, Elisa was nursing Noah when she realized something was wrong with her son. “I went to sit him up and he just fell over. I did it again and the same thing happened.” When she realized he wasn’t moving his feet, legs or toes, she called her son’s ped...
Source: Thrive, Children's Hospital Boston - May 2, 2016 Category: Pediatrics Authors: Lisa Fratt Tags: Our Patients’ Stories Department of Neurology Dr. Donna Nimec Dr. Mark Gorman enterovirus D68 Guillain Barre Syndrome Source Type: news

Reversible Motor Paralysis and Early Cardiac Rehabilitation in Patients With Advanced Heart Failure Receiving Left Ventricular Assist Device Therapy.
We report on a 58-year-old male patient with a previous history of poliomyelitis and a light paralysis in the left upper extremity, who suffered left hemiplegia with no evidence of stroke after hemodynamic deterioration. The combination therapy of perioperative cardiac rehabilitation and LVAD therapy improved his left hemiplegia as well as activities of daily living, and the patient was discharged on foot on postoperative day 72 after briefing the family on LVAD home management. Early initiation of cardiac rehabilitation before LVAD implantation may be a key for the smooth discharge and resocialization of patients sufferin...
Source: International Heart Journal - November 12, 2016 Category: Cardiology Tags: Int Heart J Source Type: research

For Humanitarian Workers, Mental Health Needs Are Often Overlooked
July 19, 2017It ' s time to take mental well-being during complex emergencies seriously.In my family there was always a strong culture of suffering in silence. We were encouraged as children to ignore small injuries and illnesses, and to soldier on without complaint.I only realized the full extent of this embedded behavior when my elderly mother dislocated her shoulder and refused to go to the hospital for 24 hours, somehow believing that it would get better on its own.It has always been difficult to shake off this deeply ingrained sense that to ask for help is somehow weak. When, in a one year period, my son had a serious...
Source: IntraHealth International - July 19, 2017 Category: International Medicine & Public Health Authors: mnathe Source Type: news

10 Global Health Issues to Watch in 2018
January 19, 2018It ’s notallbad news.When we set out to compile our annual list of global health issues to watch this year, it seemed like all bad news. And true, that ’s often what we deal with in global health—the problems that need tackling, the suffering we can help alleviate.But then stories and columns likethis one cheer us up. They remind us that no matter how complicated and frustrating our work may get, fighting back against poverty and inequality works.There are and always will be global health challenges to face. But there ’s boundless hope, too. And a field full of determined health workers and other hu...
Source: IntraHealth International - January 19, 2018 Category: International Medicine & Public Health Authors: mnathe Source Type: news

CDC Director Resigns Amid Reports of Tobacco Stock Trade
The Department of Health and Human Services (HHS) announced on January 31, 2018, that Dr. Brenda Fitzgerald would resign as the Director of the Centers for Disease Control and Prevention (CDC). The statement read, “Dr. Fitzgerald owns certain complex financial interests that have imposed a broad recusal limiting her ability to complete all of her duties as the CDC Director. Due to the nature of these financial interests, Dr. Fitzgerald could not divest from them in a definitive time period.” The decision came a day after Politico reported that she bought stock in a large tobacco company within a month of start...
Source: Public Policy Reports - February 5, 2018 Category: Biology Authors: AIBS Source Type: news

Mechanoadaptation: articular cartilage through thick and thin.
This article is protected by copyright. All rights reserved. PMID: 29917242 [PubMed - as supplied by publisher]
Source: The Journal of Physiology - June 19, 2018 Category: Physiology Authors: Vincent TL, Wann A Tags: J Physiol Source Type: research

Orthopaedic surgery for patients with central nervous system lesions: concepts and techniques
Publication date: Available online 2 October 2018Source: Annals of Physical and Rehabilitation MedicineAuthor(s): F Genêt, P Denormandie, MA KeenanAbstractSince ancient times, the aim of orthopedic surgery has been to correct limb and joint deformities, including those resulting from central nervous system lesions. Recent developments in the treatment of spasticity have led to changes in concepts and management strategies. The increase in life expectancy has increased the functional needs of patients. Orthopedic surgery, along with treatments for spasticity, improves the functional capacity of patients with neuro-orthopae...
Source: Annals of Physical and Rehabilitation Medicine - October 5, 2018 Category: Rehabilitation Source Type: research

Novartis ’ Spinal Drug Gets FDA Approval, $2 Million Price Tag
(CNN) — The US Food and Drug Administration approved a treatment Friday for a genetic disease called spinal muscular atrophy that causes infants’ muscles to waste away, potentially killing them before age 2. And then came the price tag: $2.125 million for a one-time treatment. The gene therapy, called Zolgensma, will be marketed by AveXis, whose parent company is Novartis. “Today’s approval marks another milestone in the transformational power of gene and cell therapies to treat a wide range of diseases,” Dr. Ned Sharpless, the FDA’s acting commissioner, said in a statement Friday. ̶...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - May 24, 2019 Category: Consumer Health News Authors: Health – CBS Boston Tags: Health News CNN Novartis Source Type: news

Preface
Growing up in rural South India, I witnessed the lifelong effects of polio in my great-uncle and the effects of disability in my grandfather after he suffered a stroke. There were minimal access to health care of any type and no access to medical rehabilitation.
Source: Physical Medicine and Rehabilitation Clinics of North America - September 26, 2019 Category: Rehabilitation Authors: Joseph P. Jacob Source Type: research

Acute Flaccid Myelitis: A Clinical Review
Semin Neurol DOI: 10.1055/s-0040-1705123Acute flaccid myelitis (AFM) is an emerging disorder primarily affecting children that is characterized by acute flaccid paralysis accompanied by abnormalities of the spinal cord gray matter on magnetic resonance imaging. In most cases, prodromal fever or respiratory symptoms occur, followed by acute-onset flaccid limb weakness. Respiratory, axial, bulbar, facial, and extraocular muscles may also be affected. The clinical manifestations have been described as “polio-like,” due to striking similarities to cases of poliomyelitis. The primary site of injury in AFM is the anterior ho...
Source: Seminars in Neurology - March 5, 2020 Category: Neurology Authors: Murphy, Olwen C. Pardo, Carlos A. Tags: Review Article Source Type: research

Medical Comorbidities and Complications Associated with Poliomyelitis and Its Sequelae
Survivors of poliomyelitis may experience long-term sequelae that put them at increased risk for injury, pain, cardiovascular deconditioning, and functional decline. Osteoporotic fractures and entrapment neuropathies, in particular, may result in greater impairments in one ’s mobility and ability to perform activities of daily living. Dysphagia may necessitate the use of compensatory swallow strategies to minimize aspiration risk. Comorbid conditions, including hypertension, dyslipidemia, obesity, and stroke, are also very prevalent in this population. Risk factor m odification, including diet, exercise, and medication c...
Source: Physical Medicine and Rehabilitation Clinics of North America - May 19, 2021 Category: Rehabilitation Authors: Lauren T. Shapiro, Andrew L. Sherman Source Type: research