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Total 3962 results found since Jan 2013.

A prospective reappraisal of motor outcome prediction in patients with acute stroke by using atlas-based diffusion tensor imaging biomarkers
CONCLUSIONS: Atlas-based DTI-derived metrics at acute stage provide objective information for prognosis prediction of patients with ischemic or lacunar stroke.PMID:37209060 | DOI:10.1080/10749357.2023.2214977
Source: Topics in Stroke Rehabilitation - May 20, 2023 Category: Neurology Authors: Yung-Chieh Chen Sho-Jen Cheng Li-Chun Hsieh Hann-Yeh Shyu Ming-Hua Chen Cheng-Yu Chen Duen-Pang Kuo Source Type: research

Establishing a pediatric acute stroke protocol: experience of a new pediatric stroke program and predictors of acute stroke
ConclusionA trainee developed and initiated pediatric acute stroke protocol quickly implemented a hospital wide change in management that led to rapid diagnosis and triage of pediatric stroke and suspected stroke. No additional personnel or resources were needed for this change, and we encourage other hospitals and emergency departments to implement similar systems. Additionally, hemiparesis and altered mental status were predictors of stroke for pediatric acute stroke activation in our Bayesian statistical analysis. However credible intervals were wide due to the small sample size. Further multicenter data collection coul...
Source: Frontiers in Neurology - May 18, 2023 Category: Neurology Source Type: research

Roche ’s BTK inhibitor fenebrutinib significantly reduced brain lesions in people with relapsing forms of multiple sclerosis
Fenebrutinib is an investigational, potent and highly selective oralBruton ’s tyrosine kinase (BTK) inhibitor, the only reversible BTK inhibitor currently in Phase III multiple sclerosis (MS) trialsPhase II study met its primary and secondary endpoints by reducing the total number of new gadolinium-enhancing T1 brain lesions and significantly reducing the total number of new or enlarging T2 brain lesions compared to placeboThe safety profile offenebrutinib was consistent with previous and ongoing clinical trials across more than 2,400 people to dateBasel, 17 May 2023 - Roche (SIX: RO, ROG; OTCQX: RHHBY) announced today p...
Source: Roche Media News - May 17, 2023 Category: Pharmaceuticals Source Type: news

Analysis of the sensitivity and specificity of compressed sensing magnetic resonance imaging in the diagnosis of heart failure
CONCLUSIONS: The imaging algorithm based on compressed sensing had excellent processing effect on cardiac MRI and improved the image quality. Cardiac MRI imaging had good diagnostic performance for HF and had the value of clinical popularization.PMID:37197538 | PMC:PMC10183511 | DOI:10.21037/jtd-23-190
Source: Journal of Thoracic Disease - May 17, 2023 Category: Respiratory Medicine Authors: Liguo An Jianxing Qiu Yu Zhou Jin Hui Jinchao Geng Source Type: research

The Possible Role of COVID-19 in the Triggering of Underlying Mitochondrial Dysfunction in MELAS Syndrome, A Brief Report of three cases
CONCLUSION: Although MELAS is not a prevalent condition, the recent increase in the number of these patients in our center might indicate the potential role of COVID-19 in triggering the silent pre- existing mitochondrial dysfunction in these patients.PMID:37198511
Source: Acta Neurologica Taiwanica - May 17, 2023 Category: Neurology Authors: Mahtab Ramezani Mohammad Mahdi Rabiei Zahra Cheraghi Leila Simani Source Type: research

A case with prolonged headache after COVID-19 vaccination and later developed Bell's palsy
CONCLUSION: Reactivation of latent herpes virus has been suggested as one of the possible mechanisms underlying the phenomenon, but the causal pathophysiology related to the symptom needs further validation. Moreover, in the event of facial palsy post-vaccination, alternative diagnoses such as Guillain-Barre syndrome (GBS), Ramsey-Hunt syndrome, Lyme disease, trauma, central nervous system infection (CNS) infection, or stroke should also be considered.PMID:37198509
Source: Acta Neurologica Taiwanica - May 17, 2023 Category: Neurology Authors: Yi-Yang Hsiao Ling-Jun Liu Yo-Lin Lin Source Type: research

Association between Urine Albumin-to-creatinine Ratio and Intracranial Atherosclerotic Plaque in Chinese Adults - Results from the PRECISE Study
CONCLUSIONS: Among a low-risk community-dwelling population without prior stroke or CHD in China, ACR was independently associated with intracranial plaque presence and plaque burden measured by vessel wall MRI.PMID:37197951 | DOI:10.5551/jat.64156
Source: Journal of Atherosclerosis and Thrombosis - May 17, 2023 Category: Cardiology Authors: Yin Zhang Yuesong Pan Xueli Cai Jing Jing Hongyi Yan Suying Wang Xia Meng Lerong Mei Yanli Zhang Shan Li Tiemin Wei Yilun Zhou Yongjun Wang Source Type: research

The Possible Role of COVID-19 in the Triggering of Underlying Mitochondrial Dysfunction in MELAS Syndrome, A Brief Report of three cases
CONCLUSION: Although MELAS is not a prevalent condition, the recent increase in the number of these patients in our center might indicate the potential role of COVID-19 in triggering the silent pre- existing mitochondrial dysfunction in these patients.PMID:37198511
Source: Acta Neurologica Taiwanica - May 17, 2023 Category: Neurology Authors: Mahtab Ramezani Mohammad Mahdi Rabiei Zahra Cheraghi Leila Simani Source Type: research

A case with prolonged headache after COVID-19 vaccination and later developed Bell's palsy
CONCLUSION: Reactivation of latent herpes virus has been suggested as one of the possible mechanisms underlying the phenomenon, but the causal pathophysiology related to the symptom needs further validation. Moreover, in the event of facial palsy post-vaccination, alternative diagnoses such as Guillain-Barre syndrome (GBS), Ramsey-Hunt syndrome, Lyme disease, trauma, central nervous system infection (CNS) infection, or stroke should also be considered.PMID:37198509
Source: Acta Neurologica Taiwanica - May 17, 2023 Category: Neurology Authors: Yi-Yang Hsiao Ling-Jun Liu Yo-Lin Lin Source Type: research

Analysis of the sensitivity and specificity of compressed sensing magnetic resonance imaging in the diagnosis of heart failure
CONCLUSIONS: The imaging algorithm based on compressed sensing had excellent processing effect on cardiac MRI and improved the image quality. Cardiac MRI imaging had good diagnostic performance for HF and had the value of clinical popularization.PMID:37197538 | PMC:PMC10183511 | DOI:10.21037/jtd-23-190
Source: Journal of Thoracic Disease - May 17, 2023 Category: Respiratory Medicine Authors: Liguo An Jianxing Qiu Yu Zhou Jin Hui Jinchao Geng Source Type: research

Association between Urine Albumin-to-creatinine Ratio and Intracranial Atherosclerotic Plaque in Chinese Adults - Results from the PRECISE Study
CONCLUSIONS: Among a low-risk community-dwelling population without prior stroke or CHD in China, ACR was independently associated with intracranial plaque presence and plaque burden measured by vessel wall MRI.PMID:37197951 | DOI:10.5551/jat.64156
Source: Atherosclerosis - May 17, 2023 Category: Cardiology Authors: Yin Zhang Yuesong Pan Xueli Cai Jing Jing Hongyi Yan Suying Wang Xia Meng Lerong Mei Yanli Zhang Shan Li Tiemin Wei Yilun Zhou Yongjun Wang Source Type: research

A case with prolonged headache after COVID-19 vaccination and later developed Bell's palsy
CONCLUSION: Reactivation of latent herpes virus has been suggested as one of the possible mechanisms underlying the phenomenon, but the causal pathophysiology related to the symptom needs further validation. Moreover, in the event of facial palsy post-vaccination, alternative diagnoses such as Guillain-Barre syndrome (GBS), Ramsey-Hunt syndrome, Lyme disease, trauma, central nervous system infection (CNS) infection, or stroke should also be considered.PMID:37198509
Source: Herpes - May 17, 2023 Category: Infectious Diseases Authors: Yi-Yang Hsiao Ling-Jun Liu Yo-Lin Lin Source Type: research