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Total 338 results found since Jan 2013.

A literature review of hypertensive retinopathy: systemic correlations and new technologies
CONCLUSIONS: The eye is the only organ in the human body where changes in the blood vessels due to systemic hypertension can be studied in vivo. All doctors should be familiar with this disease because it has been largely demonstrated that signs of HR are correlated to patient's health and mortality. Researchers should develop a new common, standardized, and objective method to assess hypertensive retinal changes; new technologies may have a significant role in this field. This review takes most of the literature published so far, including the OCTA studies in order to stimulate new points of reference to standardize param...
Source: European Review for Medical and Pharmacological Sciences - October 5, 2022 Category: Drugs & Pharmacology Authors: E Di Marco F Aiello M Lombardo M Di Marino F Missiroli R Mancino F Ricci C Nucci A Noce N Di Daniele M Cesareo Source Type: research

Systemic thrombolysis for acute central retinal artery occlusion in sickle cell disease: Case report
We describe a 42-year-old African- American man with SCD (HbSS) who presented with an acute central retinal artery occlusion (CRAO) within an hour of onset and subsequently received IV thrombolysis with alteplase. His labs were significant for HbS 91%. He had no central vascular access to undergo emergent red blood cell (RBC) exchange so interventional radiology was consulted to minimize his bleeding risk after receiving tissue plasminogen activator (tPA). A right internal jugular catheter was placed with fluoro-guidance, resulting in minimal blood loss. After two sessions of RBC exchange, his HbS decreased to 26%. He repo...
Source: Journal of the National Medical Association - September 26, 2022 Category: General Medicine Authors: Estevana Isaac Ali A Saherwal Shaista Alam Source Type: research

Altered synchronous neural activities in retinal vein occlusion patients: A resting-state fMRI study
ConclusionOur study demonstrated that patients with RVO were associated with abnormal synchronous neural activities in the cerebellum, middle occipital gyrus, and inferior temporal gyrus. These findings shed new insight into neural mechanisms of vision loss in patients with RVO.
Source: Frontiers in Human Neuroscience - September 16, 2022 Category: Neuroscience Source Type: research

Outcomes and Readmission in Patients With Retinal Artery Occlusion (from the Nationwide Readmission Database)
Retinal artery occlusion (RAO) is an ophthalmologic emergency, leading to sudden vision loss. Understanding its risk factors and garnering information on the incidence of adverse events can provide helpful information on the cost-effective evaluation of patients and secondary prevention. In this retrospective cohort study, we used the Nationwide Readmission Database from 2016 to 2018 and queried the database to identify patients with RAO. The clinical outcomes were cumulative incidence of myocardial infarction (MI), stroke, death (in-hospital and 6 months after discharge), resource utilization, all-cause readmission at 6 m...
Source: The American Journal of Cardiology - September 14, 2022 Category: Cardiology Authors: Kunal Suri, Monil Majmundar, Ashish Kumar, Kunal N. Patel, Xioa Yi Zhou, Harshvardhan Zala, Ankur Kalra Source Type: research

Similarities and differences in systemic risk factors for retinal artery occlusion and retinal vein occlusion: A nationwide case-control study
CONCLUSION: Differences in the level of associations with the included risk factors suggests differences in the pathophysiologies of the two diseases. The main pathophysiology associated with RAO was atherosclerosis, whereas the main pathophysiology associated with RVO was changes in the pressure gradients of the eyes.PMID:36056288 | DOI:10.1007/s10792-022-02483-3
Source: Atherosclerosis - September 2, 2022 Category: Cardiology Authors: Marie Ørskov Henrik Vorum Torben Bjerregaard Larsen Gregory Y H Lip Toke Bek Flemming Skj øth Source Type: research

Similarities and differences in systemic risk factors for retinal artery occlusion and retinal vein occlusion: A nationwide case –control study
ConclusionDifferences in the level of associations with the included risk factors suggests differences in the pathophysiologies of the two diseases. The main pathophysiology associated with RAO was atherosclerosis, whereas the main pathophysiology associated with RVO was changes in the pressure gradients of the eyes.
Source: International Ophthalmology - September 2, 2022 Category: Opthalmology Source Type: research

Role of the ABO blood groups as a risk factor for retinal vein occlusion
In this study we investigated (i) an association between blood group and the presence of RVO and (ii) whether this association correlated to other RVO risk factors. Methods We included 485 RVO patients and 295 control subjects who were recruited in this case-control study. We determined ABO genotypes rs8176719 as a marker for the O allele and rs8176746 for the B allele by polymerase chain reaction. Results We did not find an association between ABO blood gr oup and the presence of RVO. In detail, the proportion of ABO blood groups was similar among RVO patients and control subjects (p=0.527). In a logistic regression, ...
Source: Ophthalmic Research - September 1, 2022 Category: Opthalmology Source Type: research

State of target organs damage and prevalence of clinical associated conditions in patients with a hypertensive crisis and uncontrolled hypertension. (pilot study)
CONCLUSIONS: Patients with hypertensive crisis have more pronounced damage of target organs, as well as the most frequent prevalence of associated clinical conditions.PMID:36027392 | DOI:10.1097/01.hjh.0000838492.53623.dc
Source: Atherosclerosis - August 26, 2022 Category: Cardiology Authors: Tatyana Solntseva Anastasia Denisova Olga Sivakova Irina Chazova Source Type: research

State of target organs damage and prevalence of clinical associated conditions in patients with a hypertensive crisis and uncontrolled hypertension. (pilot study)
CONCLUSIONS: Patients with hypertensive crisis have more pronounced damage of target organs, as well as the most frequent prevalence of associated clinical conditions.PMID:36027392 | DOI:10.1097/01.hjh.0000838492.53623.dc
Source: Atherosclerosis - August 26, 2022 Category: Cardiology Authors: Tatyana Solntseva Anastasia Denisova Olga Sivakova Irina Chazova Source Type: research