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Total 338 results found since Jan 2013.
Plasma Retinol Binding Protein 4 as a Biomarker for Detecting Progressive Stroke and Prediction of Early Prognosis in Patients with Acute Ischemic Stroke
CONCLUSION: A low plasma RBP4 level on admission could be an independent risk factor of PS during hospitalization.PMID:34809546 | DOI:10.2174/1567202618666211122150730
Source: Current Neurovascular Research - November 23, 2021 Category: Neurology Authors: Shuqiong Liu Jiande Li Xiaoming Rong Yingmei Wei Ying Peng Qingyu Shen Source Type: research
Retinal microvascular abnormalities and risks of incident stroke and its subtypes: The Circulatory Risk in Communities Study
Conclusion:
Retinal microvascular abnormalities were positively associated with the risk of incident stroke in the general Japanese population. Routine retinal photography could provide positive clinical insights into stroke risk stratification independent of blood pressure, antihypertensive medication use, and other risk factors.
Source: Journal of Hypertension - March 10, 2022 Category: Cardiology Tags: ORIGINAL ARTICLES Source Type: research
Curcumin protects against hypertension aggravated retinal ischemia/reperfusion in a rat stroke model.
The objective of this study was to explore retinal damage in stroke spontaneously hypertensive rats (SHR) and evaluate the role of curcumin in the retinal injury after stroke. Mature male SHR were used as the animal model for hypertension and age-matched male Wistar-Kyoto (WKY) rats as the normotensive controls. The rat model of stroke was made by bilateral vertebral artery electrocoagulation combined with transient bilateral common carotid artery ligation. The animals were randomly divided into sham group, ischemia/reperfusion group, solvent control group, and curcumin treatment group. Each group was subdivided into 2 h, ...
Source: Clinical and Experimental Hypertension - July 5, 2017 Category: Cardiology Authors: Wang S, Ye Q, Tu J, Zhang M, Ji B Tags: Clin Exp Hypertens Source Type: research
Evaluation of retinal injury in a rat model of transient ischemic stroke.
This study was designed to evaluate in vivo retinal injury induced by transient global cerebral ischemia/reperfusion (I/R). A stroke-induced retinal injury model in Wistar rats was established by electrocoagulation of bilateral vertebral arteries, combined with transient ligation of the bilateral common carotid arteries. Rats were randomly divided into groups based on the time post cerebral perfusion (3 h, 24 h, 48 h, 72 h, and 7 days). Retinal injury was evaluated by histological analysis, examination of eye fundus, and TUNEL staining. The expression of protein kinase C-alpha (PKCα) and fibrillary acidic protein (GFAP) w...
Source: Histology and Histopathology - November 11, 2018 Category: Cytology Tags: Histol Histopathol Source Type: research
Eyeballing stroke: Blood flow alterations in the eye and visual impairments following transient middle cerebral artery occlusion in adult rats.
In this study, we examined the eye hemodynamics and visual deficits in middle cerebral artery occlusion-induced stroke rats. The brain and eye were evaluated by laser Doppler at baseline (prior to middle cerebral artery occlusion), during and after middle cerebral artery occlusion. Retinal function-relevant behavioral and histological outcomes were performed at 3 and 14 days post-middle cerebral artery occlusion. Laser Doppler revealed a typical reduction of at least 80% in the ipsilateral frontoparietal cortical area of the brain during middle cerebral artery occlusion compared to baseline, which returned to near-baseline...
Source: Cell Transplantation - December 31, 2019 Category: Cytology Authors: Lee JY, Castelli V, Bonsack B, García-Sánchez J, Kingsbury C, Nguyen H, Tajiri N, Borlongan CV Tags: Cell Transplant Source Type: research
Delayed retinal vein recovery responses indicate both non-adaptation to stress as well as increased risk for stroke: the SABPA study.
CONCLUSIONS: In response to low norepinephrine, a reflex increase in SAM activity occurred, enhancing arterial vasoconstriction and hypo-perfusion. Concomitant HPA dysregulation attenuated retinal vein vasoactivity and tone, reflecting delayed vein recovery responses and non-adaptation to stress. These constrained vein recovery responses are indicative of increased chronic stress and stroke risk.
PMID: 33104153 [PubMed - as supplied by publisher]
Source: Cardiovascular Journal of Africa - October 26, 2020 Category: Cardiology Authors: Malan L, Hamer M, von Känel R, Kotliar K, van Wyk RD, Lambert GW, Vilser W, Ziemssen T, Schlaich MP, Smith W, Magnusson M, Wentzel A, Myburgh CE, Steyn HS, Malan NT Tags: Cardiovasc J Afr Source Type: research
Eye signs in stroke
Rajeshwar Sahonta, Ivy Sebastian, Sanjit Aaron, Appaswamy T Prabakhar, Anupriya Arthur, Jeyaraj D PandianAnnals of Indian Academy of Neurology 2022 25(8):94-100
A large part of the central nervous system is involved in the normal functioning of the vision, and hence vision can be affected in a stroke patient. Transient visual symptoms can likewise be a harbinger of stroke and prompt rapid evaluation for the prevention of recurrent stroke. A carotid artery disease can manifest as transient monocular visual loss (TMVL), central retinal artery occlusion (CRAO), anterior ischemic optic neuropathy or ocular ischemic syndrome (...
Source: Annals of Indian Academy of Neurology - October 19, 2022 Category: Neurology Authors: Rajeshwar Sahonta Ivy Sebastian Sanjit Aaron Appaswamy T Prabakhar Anupriya Arthur Jeyaraj D Pandian Source Type: research
Risk factors for ischemic cerebral stroke in patient with acute amaurosis fugax
CONCLUSION: Ischemic stroke and myocardial infarction were diagnosed in 0.3%-0.9% of hospitalized acute AF cases. Presence of hypercoagulable state, systemic vasculitis, CAD, and atherosclerosis each individually increased the risk of ischemic stroke by more than 3-fold; patients with these risk factors and acute AF should be closely monitored for developing acute systemic thrombotic events.PMID:36368408 | DOI:10.1016/j.jcjo.2022.10.010
Source: Canadian Journal of Ophthalmology - November 11, 2022 Category: Opthalmology Authors: Tony Y Chen Aditya Uppuluri Owais Aftab Marco Zarbin Nathan Agi Neelakshi Bhagat Source Type: research
