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Total 182 results found since Jan 2013.

Behind the Headlines 2016 Quiz of the Year
In 2014, Behind the Headlines has covered more than 500 health stories that made it into the mainstream media. If you've been paying attention you should find this quiz easy and fun. Why not test your knowledge of 2014's health news with our month-by-month quiz? Answers are at the foot of the page (no peeking!).   In January 2016's health news... In a controversial study, monkeys were genetically engineered to develop what disorder? 1) Sex addiction 2) Bi-polar disorder 3) Autism In a similarly controversial study, what psychological condition was dismissed as a "myth" 1) Seasonal affective disorder...
Source: NHS News Feed - December 5, 2016 Category: Consumer Health News Tags: Special reports Source Type: news

Recanalization is the Key for Better Outcome of Thrombectomy in Basilar Artery Occlusion
ConclusionReperfusion is the major predictor of functional outcome in BAO in clinical practice. Failed recanalization resulted in a  13-fold increase of the risk of poor outcome. Successful recanalization is crucial to achieve a better functional outcome in BAO.
Source: Clinical Neuroradiology - December 22, 2019 Category: Neurology Source Type: research

The clinical and cognitive spectrum of locked-in syndrome: 1-year follow-up of 100 patients
AbstractIn patients with locked-in syndrome (LIS), it is not known exactly to what extent cognitive functions are preserved and it is not known exactly how much it has improved. We aimed to examine the clinical and cognitive features of LIS 1 year after stroke. One hundred patients with locked-in syndrome (LIS) were recruited between January 2008 and May 2019 among 8200 patients with ischemic stroke. Patients were classified into two groups as single pontine infarcts (n = 72), and pontine plus multiple ischemic lesions (PMIL) (n = 28). Since the patients had limited motor and verbal response, the cognitive status o...
Source: Acta Neurologica Belgica - May 13, 2021 Category: Neurology Source Type: research

Efficacy and safety of direct aspiration versus stent-retriever for recanalization in acute cerebral infarction: A PRISMA-compliant systematic review and meta-analysis
Conclusions: The results support that the direct aspiration technique for those acute ischemic stroke patients may have better functional outcomes, less procedure related-adverse events and a tendency of faster revascularization time as compared to the stent-retriever thrombectomy, with a similar successful recanalization rate. However, major limitations of current evidence (mainly from retrospective and observational studies and a small number of patients population) indicate a need for adequately powered, multicenter randomized controlled trials (RCT) to answer this question.
Source: Medicine - October 1, 2018 Category: Internal Medicine Tags: Research Article: Systematic Review and Meta-Analysis Source Type: research

Prognostic value of pretreatment diffusion-weighted imaging score for acute basilar artery occlusion with successful endovascular recanalization
ConclusionsThe PMT score seems to predict clinical outcome of ABAO patients with successful recanalization.
Source: Neuroradiology - February 8, 2023 Category: Radiology Source Type: research

Exploration of optimal dosing regimens of vancomycin in patients infected with methicillin‐resistant Staphylococcus aureus by modeling and simulation
Summary What is known and objectiveVancomycin is the drug of choice for methicillin‐resistant Staphylococcus aureus (MRSA) infection and shows time‐dependent bacterial killing. The current study evaluated the pharmacokinetics (PK) and pharmacodynamics (PD) of vancomycin and explored its optimal dosing regimens by modeling and simulation. MethodsPharmacokinetics study was performed for 20 patients who were treated with vancomycin intravenously, 1000 mg, every 12 h, and blood for PK was randomly drawn within prespecified time windows. PD study was in vitro time‐kill experiment for vancomycin against 20 MRSA strains i...
Source: Journal of Clinical Pharmacy and Therapeutics - January 16, 2014 Category: Drugs & Pharmacology Authors: H.‐S. Lim, Y. P. Chong, Y.‐H. Noh, J.‐A. Jung, Y. S. Kim Tags: Pharmacokinetics Source Type: research

Ruptured brain arteriovenous malformations associated with aneurysms: safety and efficacy of selective embolization in the acute phase of hemorrhage
Conclusion Selective embolization of arterial aneurysms associated with ruptured AVMs is a safe procedure and could lower the immediate risk of rebleeding.
Source: Neuroradiology - September 1, 2014 Category: Radiology Source Type: research

CDC National Health Report: Leading Causes of Morbidity and Mortality and Associated Behavioral Risk and Protective Factors-United States, 2005-2013.
This report reviews population health in the United States and provides an assessment of recent progress in meeting high-priority health objectives. The health status indicators described in this report were selected because of their direct relation to the leading causes of death and other substantial sources of morbidity and mortality and should be the focus of prevention efforts. REPORTING PERIOD COVERED: Data are reported starting in 2005 (or the earliest available year since 2005) through the current data year. Because data sources and specific indicators vary regarding when data are available, the most recent yea...
Source: MMWR Surveill Summ - October 31, 2014 Category: Epidemiology Authors: Johnson NB, Hayes LD, Brown K, Hoo EC, Ethier KA Tags: MMWR Surveill Summ Source Type: research

Mortality among methicillin-resistant Staphylococcus aureus carriers in long-term care facilities.
CONCLUSIONS: MRSA colonization among frail LTHCFs residents is highly prevalent, and is associated with higher mortality. Despite treatment of MRSA carriers, many remained colonized. Factors that promote persistence of MRSA colonization, and the impact of their modification on mortality rates in these patients, need further investigation. PMID: 25904516 [PubMed - in process]
Source: Revista Espanola de Quimioterapia - April 1, 2015 Category: Drugs & Pharmacology Authors: Vendrell E, Capdevila JA, Barrufet P, Force L, Sauca G, Martínez E, Palomera E, Serra-Prat M, Cornudella J, Llopis A, Robledo MA, Vázquez C Tags: Rev Esp Quimioter Source Type: research

Severe Cerebral Venous and Sinus Thrombosis: Clinical Course, Imaging Correlates, and Prognosis
Conclusion The outcome of severe CVT is almost equally divided between severe impairment or death and survival with no or only mild handicap. Specifically, space-occupying mass effect and associated neurologic deterioration seem to determine a poor outcome. Therefore, early detection and treatment of mass effect should be the focus of critical care.
Source: Neurocritical Care - March 20, 2016 Category: Neurology Source Type: research

Elevated Red Cell Distribution Width is Associated with Cerebral Infarction in Aneurysmal Subarachnoid Hemorrhage
ConclusionsRDW elevation is associated with cerebral infarction and poor outcome after aSAH. Further evaluation of this association is warranted as it may shed light on mechanistic relations between anemia, inflammation, and thrombosis after aSAH.
Source: Neurocritical Care - August 15, 2016 Category: Neurology Source Type: research

Clinical and radiological characteristics and predictors of outcome of cerebral venous sinus thrombosis, a hospital-based study
AbstractCerebral venous sinus thrombosis is an uncommon cause of stroke, which is more prevalent in Iran and the Middle East. We aimed to assess the etiology, radiologic, and clinical manifestations of cerebral venous sinus thrombosis, specifically the predictors of patients ’ outcome in Namazi hospital, Shiraz, Iran. In this retrospective study, we included all adult patients with the diagnosis of cerebral venous sinus thrombosis, who were admitted in hospital, from 2012 to 2016. Demographic data, radiologic findings, clinical presentation, risk factors, treatment, a nd outcome according to modified Rankin Scale (mRS) o...
Source: Acta Neurologica Belgica - September 3, 2018 Category: Neurology Source Type: research

The predictive dysphagia score (PreDyScore) in the short- and medium-term post-stroke: a putative tool in PEG indication
ConclusionBMI<  20 and mRS ≥ 3 are easily measurable bedside predictive factors of persistent dysphagia. PreDyScore showed good sensitivity and very good specificity and enables the prediction of persistent dysphagia with great accuracy in any clinical setting.
Source: Neurological Sciences - April 18, 2019 Category: Neurology Source Type: research

Prevalence, risk factors and outcomes of patients coming from the community with sepsis due to multidrug resistant bacteria
ConclusionIn light of the prevalence and impact of MDR bacteria causing sepsis in patients coming from the community, physicians should consider ESBL coverage when starting an empiric antibiotic therapy in patients with specific risk factors, especially in the presence of septic shock.
Source: Multidisciplinary Respiratory Medicine - July 4, 2019 Category: Respiratory Medicine Source Type: research