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Management of acute stroke and urgent neurointerventional procedures during COVID-19 pandemic: recommendations on the Scientific Department on Cerebrovascular Diseases of the Brazilian Academy of Neurology, Brazilian Society of Cerebrovascular Diseases and Brazilian Society of Neuroradiology
ABSTRACT Introduction: Although the 2019 severe acute respiratory syndrome coronavirus 2 infection (SARS-CoV-2, COVID-19) pandemic poses new challenges to the healthcare system to provide support for thousands of patients, there is special concern about common medical emergencies, such as stroke, that will continue to occur and will require adequate treatment. The allocation of both material and human resources to fight the pandemic cannot overshadow the care for acute stroke, a time-sensitive emergency that with an inefficient treatment will further increase mortality and long-term disability. Objective: This paper summar...
Source: Arquivos de Neuro-Psiquiatria - July 31, 2020 Category: Neurology Source Type: research

Veno-venous Extracorporeal Membrane Oxygenation for Respiratory Failure in COVID-19 Patients: Early Experience From a Major Academic Medical Center in North America
Conclusions: This is 1 the first case series describing VV ECMO outcomes in COVID-19 patients. Our initial data suggest that VV ECMO can be successfully utilized in appropriately selected COVID-19 patients with advanced respiratory failure.
Source: Annals of Surgery - July 30, 2020 Category: Surgery Tags: COVID PAPERS Source Type: research

Teleneurology during the COVID-19 pandemic: A step forward in modernizing medical care
The COVID-19 pandemic mandated rapid transition from face-to-face encounters to teleneurology visits. While teleneurology is regularly used in acute stroke care, its application in other branches of neurology was limited. Here we review how the recent pandemic has created a paradigm shift in caring for patients with chronic neurological disorders and how academic institutions have responded to the present need.
Source: Journal of the Neurological Sciences - May 20, 2020 Category: Neurology Authors: Bhaskar Roy, Richard J. Nowak, Ricardo Roda, Babar Khokhar, Huned S. Patwa, Thomas Lloyd, Seward B. Rutkove Tags: Clinical short communication Source Type: research

Adapting stroke services during the COVID-19 pandemic: an implementation guide, British Association of Stroke Physicians
Guidance for adapting stroke services during the COVID-19 pandemic – and reshaping them afterwards – has been made available in a collaboration between the Getting It Right First Time (GIRFT) programme and the Oxford Academic Health Science Network (AHSN).
Source: Current Awareness Service for Health (CASH) - May 7, 2020 Category: Consumer Health News Source Type: news

A Stroke Care Model at an Academic, Comprehensive Stroke Center During the 2020 COVID-19 Pandemic
The COVID-19 pandemic has required the adaptation of hyperacute stroke care (including stroke code pathways) and hospital stroke management. There remains a need to provide rapid and comprehensive assessment to acute stroke patients while reducing the risk of COVID-19 exposure, protecting healthcare providers, and preserving personal protective equipment (PPE) supplies. While the COVID infection is typically not a primary cerebrovascular condition, the downstream effects of this pandemic force adjustments to stroke care pathways to maintain optimal stroke patient outcomes.
Source: Journal of Stroke and Cerebrovascular Diseases - May 6, 2020 Category: Neurology Authors: Dawn Meyer, Brett C. Meyer, Karen S. Rapp, Royya Modir, Kunal Agrawal, Lovella Hailey, Melissa Mortin, Richard Lane, Tamra Ranasinghe, Brian Sorace, Tara D. von Kleist, Emily Perrinez, Mohammed Nabulsi, Thomas Hemmen Source Type: research

Nationwide Actions Against Heart Failure Pandemic in Japan 　- What Should We Do From Academia?
Nationwide Actions Against Heart Failure Pandemic in Japan　- What Should We Do From Academia? Circ J. 2019 Aug 06;: Authors: Komuro I, Kaneko H, Morita H, Isobe M, Nakayama H, Minematsu K, Yamaguchi T, Yazaki Y Abstract Heart failure pandemic is rapidly approaching in Japan, requiring nationwide actions. In particular, the Japanese Circulation Society and related societies launched the Stroke and Cardiovascular Disease Control Act, which was passed by the National Diet, as the first ever legislative policy measure against stroke and cardiovascular disease. In association with this, actions against h...
Source: Circulation Journal - August 5, 2019 Category: Cardiology Authors: Komuro I, Kaneko H, Morita H, Isobe M, Nakayama H, Minematsu K, Yamaguchi T, Yazaki Y Tags: Circ J Source Type: research

Geniposide Alleviates Glucocorticoid-Induced Inhibition of Osteogenic Differentiation in MC3T3-E1 Cells by ERK Pathway
Conclusion In summary, we demonstrated that geniposide alleviated GC-induced osteogenic suppression in MC3T3-E1 cells. The effects of geniposide were at least partially associated with activating ERK signaling pathway via GLP-1 receptor. Geniposide might be a potential therapeutic agent for protection against GC-induced osteoporosis. Author Contributions BX, DX, CZ, and LW participated in research design. BX, JW, YL, XW, and ZZ conducted the experiments. BX, DX, and LW contributed new reagents or analytic tools and wrote or contributed to the writing of the manuscript. BX, JW, CZ, and DX performed the data analysis. Fu...
Source: Frontiers in Pharmacology - April 17, 2019 Category: Drugs & Pharmacology Source Type: research

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