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Specialty: Cardiology
Education: Education

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Total 318 results found since Jan 2013.

GARFIELD-AF: risk profiles, treatment patterns and 2-year outcomes in patients with atrial fibrillation in Germany, Austria and Switzerland (DACH) compared to 32 countries in other regions worldwide
ConclusionsSimilarities and dissimilarities in AF management and clinical outcomes are seen in DACH and ORW. The increased use of NOAC was associated with a mismatch of risk-adapted anticoagulation (over-and-undertreatment) in DACH. Suboptimal control of INR requires educational activities in both regional groups. Higher rates of cardiovascular death in DACH may reflect the higher risk profile of these patients and lower rates of non-haemorrhagic stroke could be associated with increased NOAC use.Graphical abstract
Source: Clinical Research in Cardiology - September 12, 2022 Category: Cardiology Source Type: research

Carotid atherosclerosis in people of European, South Asian and African Caribbean ethnicity in the Southall and Brent revisited study (SABRE)
CONCLUSION: Prevalence of carotid artery atherosclerotic plaques varies by ethnicity, independent of risk factors. Lower plaque prevalence in in AC is consistent with their lower risk of CHD but not their higher risk of stroke. Higher cIMT in AC may be explained by risk factors. The similarity of plaque burden in SA and EA despite established differences in ASCVD risk casts some doubt on the utility of carotid ultrasound as a means of assessing risk across these ethnic groups.PMID:36762303 | PMC:PMC9902363 | DOI:10.3389/fcvm.2022.1002820
Source: Atherosclerosis - February 10, 2023 Category: Cardiology Authors: Rayan Anbar Nish Chaturvedi Sophie V Eastwood Therese Tillin Alun D Hughes Source Type: research

Hypertension in pregnancy is associated with elevated C-reactive protein levels later in life
Objectives:We assessed whether hypertension in pregnancy is associated with elevated C-reactive protein (CRP) levels in later life, possibly reflecting an increased risk of cardiovascular disease (CVD). Background:Elevated CRP levels have been associated with hypertension in pregnancy and with CVD. Methods:We studied 2463 women from the Genetic Epidemiology Network of Arteriopathy (GENOA) study. Participants were categorized as nulliparous women (n = 219), women with a history of normotensive pregnancies (n = 1839), or women with a history of a hypertensive pregnancy (n = 405). Using multiple linear regression ...
Source: Journal of Hypertension - October 8, 2013 Category: Cardiology Tags: ORIGINAL PAPERS: Pregnancy Source Type: research

Association of Ideal Cardiovascular Health Metrics and Retinal Microvascular Findings: The Atherosclerosis Risk in Communities Study Epidemiology
Conclusions Few adults had ideal cardiovascular health. Those with the best level of health were less likely to have retinopathy signs, wide retinal venules, and narrow retinal arterioles, which are associated with increased stroke and coronary heart disease risk.
Source: JAHA:Journal of the American Heart Association - November 19, 2013 Category: Cardiology Authors: Ogagarue, E. R., Lutsey, P. L., Klein, R., Klein, B. E., Folsom, A. R. Tags: Epidemiology Source Type: research

Early Adoption of Dabigatran and Its Dosing in US Patients With Atrial Fibrillation: Results From the Outcomes Registry for Better Informed Treatment of Atrial Fibrillation Health Services and Outcomes Research
Conclusions Patients receiving dabigatran were younger and at a lower risk of stroke and bleeding. Patients appeared to drive switching from warfarin, whereas clinical characteristics influenced de novo start of dabigatran. These data suggest cautious early uptake of dabigatran, and more careful attention to dosing adjustments is warranted. Clinical Trial Registration URL: Clinicaltrials.gov. Unique identifier: NCT01165710.
Source: JAHA:Journal of the American Heart Association - November 25, 2013 Category: Cardiology Authors: Steinberg, B. A., Holmes, D. N., Piccini, J. P., Ansell, J., Chang, P., Fonarow, G. C., Gersh, B., Mahaffey, K. W., Kowey, P. R., Ezekowitz, M. D., Singer, D. E., Thomas, L., Peterson, E. D., Hylek, E. M., The Outcomes Registry for Better Informed Treatme Tags: Health Services and Outcomes Research Source Type: research

Use of drug treatment for secondary prevention of cardiovascular disease in urban and rural communities of China: China Kadoorie Biobank Study of 0.5million people
Conclusions: Despite recent improvements in hospital care in China, only one in three individuals with prior CVD was routinely treated with any proven secondary preventive drugs. The treatment rates were correlated with the existence of other risk factors, in particular evidence of hypertension.
Source: International Journal of Cardiology - January 23, 2014 Category: Cardiology Authors: Yiping Chen, Liming Li, Qiuli Zhang, Robert Clarke, Junshi Chen, Yu Guo, Zheng Bian, Xianhai Pan, Richard Peto, Ran Tao, Kunxiang Shi, Rory Collins, Liangcai Ma, Huarong Sun, Zhengming Chen, on behalf of China Kadoorie Biobank Study Tags: Original Articles Source Type: research

Association between serum uric acid levels and cardiovascular disease in middle-aged and elderly Chinese individuals
This study sought to determine whether elevated serum uric acid levels are associated with cardiovascular disease (CVD) in middle-aged and elderly Chinese individuals. Methods: We conducted a population-based cross-sectional study in Shanghai, with a total of 8510 participants aged>=40 years. The CVD included diagnosed coronary heart disease (CHD) and stroke. MetS was defined according to the updated National Cholesterol Education Program Adult Treatment Panel III criteria for Asian Americans. Results: Uric acid levels were positively associated with BMI, waist circumference, triglycerides, systolic blood pressure, diastol...
Source: BMC Cardiovascular Disorders - February 25, 2014 Category: Cardiology Authors: Li QinZhen YangHongxia GuShuai LuQun ShiYin XingXiaoyong LiRui LiGuang NingQing Su Source Type: research

An Effective Approach to High Blood Pressure Control A Science Advisory From the American Heart Association, the American College of Cardiology, and the Centers for Disease Control and Prevention
Cardiovascular diseases, including heart disease, hypertension, and heart failure, along with stroke, continue to be leading causes of death in the United States (1,22). Hypertension currently affects nearly 78 million∗∗∗The estimate is based on the hypertension definition of blood pressure reading ≥140/90 mm  Hg, current use of antihypertensive medications, or being told about having hypertension on 2 occasions by a healthcare provider. When the third component of the definition is excluded, the estimated number of prevalence cases among U.S. adults would be 67 million (3). adults in the United States and is al...
Source: Journal of the American College of Cardiology: Cardiovascular Interventions - March 24, 2014 Category: Cardiology Source Type: research

Untreated atrial fibrillation in the United Kingdom: Understanding the barriers and treatment options
This article reviews the barriers to anticoagulation in patients with AF in the United Kingdom and considers how those barriers may be overcome.
Source: Journal of the Saudi Heart Association - November 3, 2014 Category: Cardiology Source Type: research

Low Cardiac Index is Associated with Incident Dementia and Alzheimer's Disease: The Framingham Heart Study.
CONCLUSIONS: -Lower cardiac index is associated with an increased risk for the development of dementia and AD. PMID: 25700178 [PubMed - as supplied by publisher]
Source: Circulation - February 19, 2015 Category: Cardiology Authors: Jefferson AL, Beiser AS, Himali JJ, Seshadri S, O'Donnell CJ, Manning WJ, Wolf PA, Au R, Benjamin EJ Tags: Circulation Source Type: research

Health-Related Quality of Life in Coronary Heart Disease in Korea: The Korea National Health and Nutrition Examination Survey 2007 to 2011
Using data from 2007 to 2011 of the Korea National Health and Nutrition Examination Survey, we evaluated the influence of coronary heart disease (CHD) on health-related quality of life (HRQoL) as measured by the EQ-5D in comparison with the general population and the predictors of HRQoL in CHD. Compared with the general population, HRQoL was impaired in the EQ-5D dimensions of mobility, usual activities, pain/discomfort, and anxiety/depression. The impairment of HRQoL was much greater in the older age group and in females. In subjects with CHD, the predictors for a low EQ-5D index were old age, female sex, low education, s...
Source: Angiology - April 9, 2015 Category: Cardiology Authors: Lee, H. T., Shin, J., Lim, Y.-H., Kim, K. S., Kim, S. G., Kim, J. H., Lim, H. K. Tags: Coronary Heart Diseases Source Type: research

Patent foramen ovale: the current state of play
Learning objectives Understand the anatomy and embryology of the interatrial septum and patent foramen ovale (PFO). Develop an overview of the many clinical associations of a PFO. Appraise the clinical evidence for and against closure of PFO. Introduction Patent foramen ovale (PFO) is a common finding, occurring in up to 25% of people.1 2 An association between PFO and stroke has consistently been seen in up to 50% of patients without an identifiable cause, that is, the so-called cryptogenic stroke (CS) and only in 20% with an identified cause.3 4 Many studies have been published testing the hypothesis that paradoxical emb...
Source: Heart - November 12, 2015 Category: Cardiology Authors: Asrress, K. N., Marciniak, M., Marciniak, A., Rajani, R., Clapp, B. Tags: Education in Heart, Echocardiography, Clinical diagnostic tests Source Type: research

Choice of New Oral Anticoagulant Agents Versus Vitamin K Antagonists in Atrial Fibrillation: FANTASIIA Study
Conclusion: Medical and social variables were associated with prescription of NOAC. Major bleeding, hemorrhagic stroke, university education, and higher glomerular filtration rate were more frequent among patients under NOAC. On the contrary, patients with history of cancer or bradyarrhythmias more frequently received VKA.
Source: Journal of Cardiovascular Pharmacology and Therapeutics - February 24, 2016 Category: Cardiology Authors: Moreno-Arribas, J., Bertomeu-Gonzalez, V., Anguita-Sanchez, M., Cequier, A., Muniz, J., Castillo, J., Sanchis, J., Roldan, I., Marin, F., Bertomeu-Martinez, V., on behalf of the investigators of the FANTASIIA study Tags: Clinical Studies Source Type: research

A clustered randomized trial to IMProve treatment with AntiCoagulanTs in patients with Atrial Fibrillation (IMPACT AF): design and rationale
The objective of this prospective, cluster randomized controlled trial (IMPACT-AF; ClinicalTrials.gov #NCT02082548) is to determine whether a comprehensive customized intervention will increase the rate and persistence of use of OAC in patients with AF. IMPACT-AF will be conducted in approximately 50 centers in 5 low- to middle-income countries. Before randomization, sites within countries will be paired to match in size, practice type and baseline rate of OAC use. Site pairs will be randomized to intervention versus control. In total, 40 to 70 patients with AF and at least 2 CHA2DS2-VASc risk factors will be enrolled at e...
Source: American Heart Journal - March 21, 2016 Category: Cardiology Source Type: research

Non-vitamin K antagonist oral anticoagulants (NOACs) for the management of venous thromboembolism
Learning objectives Understand the importance of venous thrombosis in cardiovascular medicine. Appreciate the mode of action of different oral anticoagulants. Recall the uses, risks and benefits of each non-vitamin K antagonist oral anticoagulants. Introduction Thrombosis is the common pathophysiology responsible for ischaemic heart disease, ischaemic stroke and venous thromboembolism (VTE), and a major contributor to the global disease burden.1 This effect is markedly more pronounced by considering the view that cancer is also a thrombotic disease.2 3 Cardiovascular disease (CVD, manifesting as acute coronary syndromes, m...
Source: Heart - June 5, 2016 Category: Cardiology Authors: Blann, A. D., Lip, G. Y. H. Tags: Education in Heart, Drugs: cardiovascular system, Acute coronary syndromes, Venous thromboembolism, Epidemiology Source Type: research