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Yale study revives cellular activity in pig brains hours after death
Yale University scientists have succeeded in restoring basic cellular activity in pigs' brains hours after their deaths in a finding that may one day lead to advances in treating human stroke and brain injuries, researchers reported on Wednesday.
Source: Reuters: Health - April 18, 2019 Category: Consumer Health News Tags: healthNews Source Type: news
Scientists Restore Some Brain Activity in Recently Slaughtered Pigs
(NEW YORK) — Scientists restored some activity within the brains of pigs that had been slaughtered hours before, raising hopes for some medical advances and questions about the definition of death.
The brains could not think or sense anything, researchers stressed. By medical standards “this is not a living brain,” said Nenad Sestan of the Yale School of Medicine, one of the researchers reporting the results Wednesday in the journal Nature.
But the work revealed a surprising degree of resilience among cells within a brain that has lost its supply of blood and oxygen, he said.
“Cell death in the brai...
Source: TIME: Health - April 17, 2019 Category: Consumer Health News Tags: Uncategorized Brain Activity onetime Source Type: news
Yale Study Revives Cellular Activity in Pig Brains Hours After Death Yale Study Revives Cellular Activity in Pig Brains Hours After Death
Yale University scientists have succeeded in restoring basic cellular activity in pigs ' brains hours after their deaths in a finding that may one day lead to advances in treating human stroke and brain injuries, researchers reported on Wednesday.Reuters Health Information
Source: Medscape Transplantation Headlines - April 18, 2019 Category: Transplant Surgery Tags: Neurology & Neurosurgery News Source Type: news
Early Prognostication of 1-Year Outcome After Subarachnoid Hemorrhage: The FRESH Score Validation
Background and Aim: The FRESH score is a tool to prognosticate long-term outcomes after spontaneous subarachnoid hemorrhage (SAH). Here, for the first time, we aimed to externally validate the disability part of FRESH using its original four score variables. Methods: A total of 107 patients with SAH were prospectively enrolled in the Yale Acute Brain Injury Biorepository between September 2014 and January 2018. 12-month functional outcome was recorded prospectively by trained study investigators using the modified Rankin Scale (mRS).
Source: Journal of Stroke and Cerebrovascular Diseases - July 17, 2019 Category: Neurology Authors: Jens Witsch, Lindsey Kuohn, Ryan Hebert, Branden Cord, Lauren Sansing, Emily J. Gilmore, David Y. Hwang, Nils Petersen, Guido J. Falcone, Charles Matouk, Kevin N. Sheth Source Type: research
12 Innovations That Will Change Health Care and Medicine in the 2020s
Pocket-size ultrasound devices that cost 50 times less than the machines in hospitals (and connect to your phone). Virtual reality that speeds healing in rehab. Artificial intelligence that’s better than medical experts at spotting lung tumors. These are just some of the innovations now transforming medicine at a remarkable pace.
No one can predict the future, but it can at least be glimpsed in the dozen inventions and concepts below. Like the people behind them, they stand at the vanguard of health care. Neither exhaustive nor exclusive, the list is, rather, representative of the recasting of public health and medic...
Source: TIME: Health - October 25, 2019 Category: Consumer Health News Authors: TIME Staff Tags: Uncategorized HealthSummit19 technology Source Type: news
Not all hypertension drugs are created equal, reports big-data study
A massive study of over 4.9 million patients has found that diuretics are better at preventing heart attack, heart failure, and stroke than ACE inhibitors.
Source: Yale Science and Health News - October 25, 2019 Category: Universities & Medical Training Source Type: news
This Under-Utilized Drug Is Actually Critical for Treatment-Resistant Depression
Many people with clinical depression have tried an array of medication and still feel sick. Maybe they’ve tried different selective serotonin reuptake inhibitors (SSRIs) or selective norepinephrine reuptake inhibitors (SNRIs). Maybe they’ve taken these antidepressants along with an antipsychotic (a common strategy to boost effectiveness).
Either way, the lack of improvement can make individuals feel even more hopeless and fear the darkness will never lift.
If this sounds all-too familiar, you’re definitely not alone. In fact, up to 30 percent of people with depression don’t respond to the first few antidepressants ...
Source: Psych Central - November 27, 2019 Category: Psychiatry Authors: Margarita Tartakovsky, M.S. Tags: Antidepressants Depression Disorders ECT General Medications Treatment Atypical Depression difficult to treat depression Managing Depression MAOIs medication for depression Monoamine Oxidase Inhibitors Severe Depression Treatin Source Type: news
Hyperfine touts stroke study for portable MRI scanner
Healthcare technology firm Hyperfine Research is touting the results of a preliminary...Read more on AuntMinnie.comRelated Reading:
FDA clears Hyperfine's bedside MRI scanner
Video from J.P. Morgan: Portable MRI takes to the streets
Hyperfine partners with Nvidia, Penn Medicine on portable MRI system
Hyperfine shows point-of-care MRI scanner at ACEP 2019
Yale tests point-of-care MRI scanner for ICU
Source: AuntMinnie.com Headlines - February 13, 2020 Category: Radiology Source Type: news
A portable MRI might help save your life, especially after a stroke
Logistics have long kept doctors from getting the brain imaging they need in time-sensitive situations. But now Yale doctors have deployed a novel solution.
Source: Yale Science and Health News - February 28, 2020 Category: Universities & Medical Training Source Type: news
WHRY funds studies on stroke, endometrial cancer, and addiction to opioids
Women ’s Health Research at Yale is expanding its work to “address the enduring and pressing medical conditions that continue to affect women’s lives.”
Source: Yale Science and Health News - May 21, 2020 Category: Universities & Medical Training Source Type: news
Improvements in stroke treatment could save more lives
Direct carotid puncture (DCT) can offer a surprisingly safe alternative to the standard mechanical thrombectomy for patients with difficult-to-access arteries.
Source: Yale Science and Health News - October 9, 2020 Category: Universities & Medical Training Source Type: news
Causal Link Suggested for Smoking, Subarachnoid Hemorrhage
THURSDAY, Jan. 14, 2021 -- Evidence suggests a causal link between smoking and the risk for subarachnoid hemorrhage (SAH), according to a study published online Jan. 14 in Stroke.
Juli án N. Acosta, M.D., from the Yale School of Medicine in New...
Source: Drugs.com - Pharma News - January 14, 2021 Category: Pharmaceuticals Source Type: news
Relation of Cardiovascular Risk Factors to Mortality and Cardiovascular Events in Hospitalized Patients with Coronavirus Disease 2019 (From the Yale COVID-19 Cardiovascular Registry)
Individuals with established cardiovascular disease or a high burden of cardiovascular risk factors may be particularly vulnerable to develop complications from coronavirus disease 2019 (COVID-19). We conducted a prospective cohort study at a tertiary care center to identify risk factors for in-hospital mortality and major adverse cardiovascular events (MACE; a composite of myocardial infarction, stroke, new acute decompensated heart failure, venous thromboembolism, ventricular or atrial arrhythmia, pericardial effusion, or aborted cardiac arrest) among consecutively hospitalized adults with COVID-19, using multivariable b...
Source: The American Journal of Cardiology - February 1, 2021 Category: Cardiology Authors: Manan Pareek, Avinainder Singh, Lina Vadlamani, Maxwell Eder, Justin Pacor, Jakob Park, Zaniar Ghazizadeh, Alex Heard, Ana Sofia Cruz-Solbes, Roozbeh Nikooie, Chad Gier, Zain V. Ahmed, James V. Freeman, Judith Meadows, Kim G.E. Smolderen, Rachel Lampert, Source Type: research
Validation of the Italian Version of the Functional Oral Intake Scale (FOIS-It) Against Fiberoptic Endoscopic Evaluation of Swallowing and Nutritional Status
AbstractThe Functional Oral Intake Scale (FOIS) is a reliable and valid tool to assess functional oral intake of food and liquids in patients with oropharyngeal dysphagia (OD). Its validity was established for stroke patients against Videofluoroscopic Swallowing Study in English and Chinese and against Fiberoptic Endoscopic Evaluation of Swallowing (FEES) in German. FOIS was cross-culturally validated into Italian (FOIS-It), but construct validity against instrumental assessment and nutritional status was not investigated. The study aims at contributing to the validation of the FOIS-It, by performing convergent and known-g...
Source: Dysphagia - February 16, 2021 Category: Speech-Language Pathology Source Type: research
Yale neurologists identify consistent neuroinflammatory response in ICH patients
(Yale University) Understanding how the immune system responds to acute brain hemorrhage could open doors to identifying treatments for this devastating disease. However, up until now, there has been limited information on inflammation in the brain from human patients, especially during the first days after a hemorrhagic stroke.This led a team of researchers to partner with a large clinical trial of minimally-invasive surgery to tackle defining the human neuroinflammatory response in living patients.
Source: EurekAlert! - Medicine and Health - February 22, 2021 Category: International Medicine & Public Health Source Type: news
