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Total 35 results found since Jan 2013.

O-007 Bridging thrombolysis yields diminished benefit among elderly stroke patients treated with endovascular thrombectomy
ConclusionsBridging thrombolysis may be associated with better outcomes in a real-world setting; however, this association is diminished among elderly patients due to higher rates of hemorrhagic complications. Meta-analyses of trial data and future prospective studies are needed to fully elucidate the benefits and risks of bridging thrombolysis in the elderly population.Abstract O-007 Figure 1Disclosures H. Chen: None. M. Khunte: None. M. Colasurdo: None. A. Malhotra: None. D. Gandhi: 1; C; National Institutes of Health, Focused Ultrasound Foundation, MicroVention, University of Calgary, University of Maryland Medical Center.
Source: Journal of NeuroInterventional Surgery - July 30, 2023 Category: Neurosurgery Authors: Chen, H., Khunte, M., Colasurdo, M., Malhotra, A., Gandhi, D. Tags: SNIS 20th annual meeting oral abstracts Source Type: research

P-005 Predictors for large vessel recanalization before stroke thrombectomy
ConclusionsIVT at least 1.5 hours before angiography, site of vascular occlusion, atrial fibrillation, and hyperlipidemia are independent predictors for LVR. The 8-point Recan score proposed in this study may be a valuable tool for predicting LVR before EVT.Abstract P-005 Figure 1Disclosures H. Chen: None. M. Colasurdo: None. C. Schrier: None. M. Khalid: None. M. Khunte: None. T. Miller: None. J. Cherian: None. A. Malhotra: None. D. Gandhi: 1; C; National Institutes of Health, Focused Ultrasound Foundation, MicroVention, University of Calgary, University of Maryland Medical Center.
Source: Journal of NeuroInterventional Surgery - July 30, 2023 Category: Neurosurgery Authors: Chen, H., Colasurdo, M., Schrier, C., Khalid, M., Khunte, M., Miller, T., Cherian, J., Malhotra, A., Gandhi, D. Tags: SNIS 20th annual meeting oral poster abstracts Source Type: research

MRI for all: Cheap portable scanners aim to revolutionize medical imaging
.news-article__hero--featured .parallax__element{ object-position: 47% 50%; -o-object-position: 47% 50%; } The patient, a man in his 70s with a shock of silver hair, lies in the neuro intensive care unit (neuro ICU) at Yale New Haven Hospital. Looking at him, you’d never know that a few days earlier a tumor was removed from his pituitary gland. The operation didn’t leave a mark because, as is standard, surgeons reached the tumor through his nose. He chats cheerfully with a pair of research associates who have come to check his progress with a new and potentially revolutionary device they are testing. The cylind...
Source: Science of Aging Knowledge Environment - February 23, 2023 Category: Geriatrics Source Type: research

Neurologic Outcomes After Extracorporeal Cardiopulmonary Resuscitation: Recent Experience at a Single High-Volume Center
This study describes the recent ECPR experience at the University of Maryland Medical Center from 2016 through 2018, with attention to neurologic outcomes and predictors thereof. The primary outcome was dichotomized Cerebral Performance Category (≤2) at hospital discharge; secondary outcomes included rates of specific neurologic complications. From 429 ECMO runs over 3 years, 57 ECPR patients were identified, representing an increase in ECPR utilization compared with 41 cases over the previous 6 years. Fifty-two (91%) suffered in-hospital cardiac arrest, and 36 (63%) had an initial nonshockable rhythm. Median low-flow ti...
Source: ASAIO Journal - February 1, 2022 Category: Medical Devices Tags: Clinical Critical Care Source Type: research

IMAGES: Polysomnographic findings of nystagmus caused by a midbrain hemorrhagic stroke
Journal of Clinical Sleep Medicine, Ahead of Print.
Source: Journal of Clinical Sleep Medicine : JCSM - January 28, 2022 Category: Sleep Medicine Authors: Umer Shoukat Danielle R. Glick Seemant Chaturvedi Montserrat Diaz-Abad 1University of Maryland Sleep Disorders Center, University of Maryland Medical Center, Baltimore, Maryland 2Department of Neurology & Stroke Program, University of Maryland School of Source Type: research

CPAP adherence is associated with reduced risk for stroke among older adult Medicare beneficiaries with obstructive sleep apnea
Journal of Clinical Sleep Medicine,<a href="https://jcsm.aasm.org/toc/jcsm/17/6">Volume 17, Issue 6</a>, Page 1249-1255, June 2021.
Source: Journal of Clinical Sleep Medicine : JCSM - June 1, 2021 Category: Sleep Medicine Authors: Emerson M. WickwireM. Doyinsola BaileyVirend K. SomersMukta C. SrivastavaSteven M. ScharfAbree M. JohnsonJennifer S. Albrecht1Department of Psychiatry, University of Maryland School of Medicine, Baltimore, Maryland2Sleep Disorders Center, Division of Pulm Source Type: research

Emerging from the fog: Little understood post-stroke cognitive issues are verified
(University of Maryland) For the first time, researchers at the University of Maryland have measured the physical evidence of diminished neural processing within the brain after a stroke.
Source: EurekAlert! - Medicine and Health - December 14, 2020 Category: International Medicine & Public Health Source Type: news

Having high cholesterol levels early in life leads to heart problems by middle age
(University of Maryland School of Medicine) Having elevated cholesterol during the teens or early twenties increases a person's risk of having a heart attack, stroke or other cardiovascular event during middle age. That is the finding a new landmark study led by researchers at the University of Maryland School of Medicine (UMSOM).
Source: EurekAlert! - Medicine and Health - September 22, 2020 Category: International Medicine & Public Health Source Type: news

Robot-Assisted Therapy in Upper Extremity Hemiparesis: Overview of an Evidence-Based Approach
Conclusion Robotic therapy has matured and represents an embodiment of a paradigm shift in neurorehabilitation following a stroke: instead of focusing on compensation, it affords focus in ameliorating the impaired limb in line with concepts of neuroplasticity. This technology-based treatment provides intensity, interactivity, flexibility, and adaptiveness to patient's performance and needs. Furthermore, it increases the productivity of rehabilitation care. Of course, efficiency must be discussed within a local perspective. For example, following the cost containment shown in the VA ROBOTICS study (46), the UK Nati...
Source: Frontiers in Neurology - April 23, 2019 Category: Neurology Source Type: research

Why is Clinical fMRI in a Resting State?
Conclusions Despite some perceived impediments to expanding clinical rs-fMRI use, neuroradiologists were generally enthusiastic about rs-fMRI in research and clinical applications, believing that their current workplace MRI systems are suitable for rs-fMRI acquisition. Many of the concerns associated with using rs-fMRI in clinical contexts are related to: (1) developing better methods for minimizing physiological noise effects, (2) improving methods for detecting the spatial characteristics of clinically-relevant brain processing systems in individual patients, and (3) overcoming remaining standardization, training, and r...
Source: Frontiers in Neurology - April 23, 2019 Category: Neurology Source Type: research

The Promoter Regions of Intellectual Disability-Associated Genes Are Uniquely Enriched in LTR Sequences of the MER41 Primate-Specific Endogenous Retrovirus: An Evolutionary Connection Between Immunity and Cognition
Discussion We have found that, in the human genome, the promoter regions of ID-associated genes are uniquely enriched in MER41 LTRs. More specifically, nine ID-associated genes that are putatively important in cognitive evolution exhibit MER41 LTRs in their promoter regions. As more than 100 families of HERV are integrated into our genome, it was important to determine whether our findings are specific to MER41 and to ID-associated genes, and if so to what extent. Among the 133 families of HERV explored here, MER41 is the only family whose LTRs were found with statistically high frequency in the promoter regions of ID-ass...
Source: Frontiers in Genetics - April 11, 2019 Category: Genetics & Stem Cells Source Type: research

As Younger Men ' s Smoking Rises, So Does Their Stroke Risk
THURSDAY, April 19, 2018 -- Men under 50 who smoke cigarettes are increasing their risk for a stroke, researchers warn. And the more they smoke, the greater their stroke risk, reported the University of Maryland investigators. The bottom line:...
Source: Drugs.com - Daily MedNews - April 19, 2018 Category: General Medicine Source Type: news

Largest-ever genetic study of stroke provides new insight into the disease
(University of Maryland School of Medicine) An international research group studying 520,000 people from around the world has identified 22 new genetic risk factors for stroke, tripling the number of gene regions known to affect stroke risk. These results provide new clues on stroke mechanisms and could help scientists identify drug targets for treatment. The work is the largest genetic study on stroke ever.
Source: EurekAlert! - Medicine and Health - March 28, 2018 Category: International Medicine & Public Health Source Type: news

Giving birth multiple times has impact on stroke recovery, study shows
(University of Maryland School of Medicine) New research published in the   Proceedings of the National Academy of Sciences shows that while perimenopausal female mice that gave birth multiple times (multiparous) were at higher risk of stroke, they recovered better than mice that had not ever reproduced.
Source: EurekAlert! - Medicine and Health - June 27, 2017 Category: International Medicine & Public Health Source Type: news

Georgia O'Keefe: Artistic and Culinary Pioneer
Pedernal Mountain. by guest blogger Pam Peeke, MD, MPH, FACP, FACSM, best-selling author and expert on health, fitness, and nutrition On a recent trip to Santa Fe, I scheduled a visit Georgia O'Keefe's home and studio in Abiquiu, New Mexico. O'Keefe, known as the mother of American modernism, is most renowned for her extraordinary paintings of super-sized erotic flowers, New York skyscrapers, and New Mexico landscapes. As I neared the property, I immediately spotted her frequently painted wooden ladder, leaning against a wall, its top rungs extending high above the rooftop. The ladder. Photo by Dr. Peeke. Stepping in...
Source: Healthy Living - The Huffington Post - August 16, 2016 Category: Consumer Health News Source Type: news