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Drug: Magnesium

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Total 11056 results found since Jan 2013.

Nonantibiotic Pharmacological Treatment of Severe Chronic Obstructive Pulmonary Disease Exacerbations
Semin Respir Crit Care Med DOI: 10.1055/s-0040-1714379Severe, acute exacerbations of chronic obstructive pulmonary disease (AECOPD) are a rapid deterioration of the respiratory symptoms of patients with COPD, requiring hospital admission and escalation of pharmacological and nonpharmacological care including the more severe cases of respiratory failure and admission to an intensive care unit (ICU). These events severely impact patients' quality of life and prognosis. This review will describe the nonantibiotic, pharmacological treatment options available for critically ill patients with AECOPD. The aim of treatment is to a...
Source: Seminars in Respiratory and Critical Care Medicine - July 28, 2020 Category: Respiratory Medicine Authors: Vasques, Francesco Camporota, Luigi Barrett, Nicholas A. Tags: Review Article Source Type: research

Age- and Sex-Specific Dynamics in 22 Hematologic and Biochemical Analytes from Birth to Adolescence Pediatric Clinical Chemistry
CONCLUSIONS: Continuous reference intervals capture the population changes in laboratory analytes during pediatric development more accurately than age groups. After local validation, the reference intervals provided should allow a more precise consideration of these dynamics in clinical decision making.
Source: Clinical Chemistry - June 26, 2015 Category: Chemistry Authors: Zierk, J., Arzideh, F., Rechenauer, T., Haeckel, R., Rascher, W., Metzler, M., Rauh, M. Tags: Pediatric Clinical Chemistry Source Type: research

Magnesium sulfate administration for the management of eclampsia: assessment of practices in university hospitals of libreville (gabon)
Publication date: Available online 26 July 2019Source: Anaesthesia Critical Care & Pain MedicineAuthor(s): P.C. Nze Obiang, P. Nzoghe Nguema, J.F. Ngomas, A. Sima Zue, H. Keita
Source: Anaesthesia, Critical Care and Pain Medicine - July 27, 2019 Category: Anesthesiology Source Type: research

Critical Care and Emergency Medicine Pharmacy Guidelines
Anyone got some good websites for a pharmacist to brush up on critical care and emergency med topics? I've been working overnights inpatient the last 3 months, and I've been noticing these topics are the main things that the residents call down to ask about. Eg: recently learned that giving Calcium won't do much if the Magnesium is also low.
Source: Student Doctor Network - November 19, 2019 Category: Universities & Medical Training Authors: Sparda29 Tags: Pharmacy Source Type: forums

Embedded point of care randomisation for evaluating comparative effectiveness questions: PROSPECTOR-critical care feasibility study protocol
This study will investigate the feasibility of using computer prompts to allow flexible randomisation at the point of clinical decision making. It will compare the effectiveness of two prompt designs through the lens of a candidate research question—comparing liberal or restrictive magnesium supplementation practices for critical care patients. It will also explore the acceptability of two consent models for conducting comparative effectiveness research. Methods and analysis We will conduct a single centre, mixed-methods feasibility study, aiming to recruit 50 patients undergoing elective surgery requiring postopera...
Source: BMJ Open - September 19, 2022 Category: General Medicine Authors: Wilson, M. G., Asselbergs, F. W., Miguel, R., Brealey, D., Harris, S. K. Tags: Open access, Health informatics Source Type: research

Should Magnesium Be Used for COPD Exacerbations? Should Magnesium Be Used for COPD Exacerbations?
Dr Holley reviews whether magnesium is beneficial or harmful when treating acute exacerbations of COPD in an emergency setting.Medscape Critical Care
Source: Medscape Emergency Medicine Headlines - August 30, 2021 Category: Emergency Medicine Tags: Pulmonary Medicine Viewpoint Source Type: news

A Statewide Study of the Epidemiology of Emergency Medical Services' Management of Pediatric Asthma
Conclusions This statewide study demonstrated low rates of EMS administration of ipratropium bromide and systemic corticosteroids, both evidence-based treatments for asthma exacerbations. Targeted EMS education should attempt to increase utilization of both those medications. In addition, the feasibility and efficacy of EMS administration of oral systemic corticosteroids for children should be explored.
Source: Pediatric Emergency Care - November 1, 2021 Category: Emergency Medicine Tags: Original Articles Source Type: research

Intravenous magnesium for pediatric sickle cell vaso‐occlusive crisis: Methodological issues of a randomized controlled trial
We describe the methods of the Intravenous Magnesium in Sickle Vaso‐occlusive Crisis (MAGiC) trial and discuss methods used to overcome past barriers. MAGiC was a multi‐center randomized double‐blind placebo‐controlled trial of intravenous magnesium versus normal saline for treatment of VOC. The study was a collaboration between Pediatric Hematologists and Emergency Physicians in the Pediatric Emergency Care Applied Research Network (PECARN). Eligible patients were randomized within 12 hours of receiving intravenous opioids in the Emergency Department (ED) and administered study medication every 8 hours. The pr...
Source: Pediatric Blood and Cancer - January 17, 2014 Category: Cancer & Oncology Authors: Oluwakemi Badaki‐Makun, J. Paul Scott, Julie A. Panepinto, T. Charles Casper, Cheryl A. Hillery, J. Michael Dean, David C. Brousseau, Tags: Research Article Source Type: research

Red blood cell transfusions during sickle cell anemia vaso-occlusive crises: a report from the magnesium in crisis (MAGiC) study.
CONCLUSION: ACS increased the RR of transfusion in children hospitalized for VOC sevenfold. In children without ACS, transfusion was associated with lowest Hb concentration, particularly Hb concentration of less than 6.3 g/dL. PMID: 28500682 [PubMed - as supplied by publisher]
Source: Transfusion - May 12, 2017 Category: Hematology Authors: Hulbert ML, Panepinto JA, Scott JP, Liem RI, Cook LJ, Simmons T, Brousseau DC, Pediatric Emergency Care and Research Network Sickle Cell Disease Working Group Tags: Transfusion Source Type: research

Magnesium supplementation: Pharmacokinetics in cardiac surgery patients with normal renal function
Conclusion Combined bolus and continuous magnesium infusion therapy leads to a significant and stable increase in magnesium serum concentration despite increased renal excretion and redistribution.
Source: Journal of Critical Care - February 27, 2018 Category: Gastroenterology Source Type: research

Outcome of status asthmaticus at a pediatric intensive care unit in Hong Kong
ConclusionsSA accounts for a small proportion of PICU admissions. LOS was short and prognosis generally good. Nonadherence to prior asthma therapy was common. The most common trigger is enterovirus/rhinovirus for children with severe asthma requiring PICU admission. A trend of increase in usage of ipratropium, magnesium sulphate and NIV was observed. Primary prevention and early treatment of exacerbation are the most important step in managing children with asthma. Regular follow up to ensure compliance together with annual vaccination could possibly avoid PICU admissions.
Source: The Clinical Respiratory Journal - January 21, 2020 Category: Respiratory Medicine Authors: Amy Cheng, Kam Lun Hon, Renee W Y Chan, Lawrence Chan, William Wong, Hon Ming Cheung, Su Yun Qian Tags: ORIGINAL ARTICLE Source Type: research

Intravenous Magnesium in Asthma Pharmacotherapy: Variability in Use in the PECARN Registry
To examine the use, efficacy, and safety of intravenous magnesium sulfate (IVMg) in children with asthma whose emergency department (ED) management is recorded in the Pediatric Emergency Care Applied Research Network (PECARN) Registry.
Source: The Journal of Pediatrics - March 4, 2020 Category: Pediatrics Authors: Michael D. Johnson, Joseph J. Zorc, Douglas S. Nelson, Theron Charles Casper, Lawrence J. Cook, Yaron Finkelstein, Lynn Babcock, Lalit Bajaj, James M. Chamberlain, Robert W. Grundmeier, Michael Webb, Elizabeth R. Alpern, Pediatric Emergency Care Applied R Tags: Original Articles Source Type: research

Magnesium Treatment in Pediatric Patients
Pediatric patients may require magnesium replacement to treat life-threatening emergencies such as torsades de pointe or asthma exacerbations, as well as for the general replacement of magnesium in patients with hypomagnesemia. Clinicians must be aware of recommendations for magnesium administration as the route, dose, timing of administration, and formulation of magnesium can differ for each indication. It is imperative for clinicians to ensure that magnesium is appropriately administered to effectively treat the presenting indication and avoid adverse effects.
Source: Journal of Pediatric Health Care - September 1, 2021 Category: Pediatrics Authors: Sarah Anderson, Elizabeth Farrington Tags: Pharmacology Continuing Education Source Type: research

Magnesium physiology and clinical therapy in veterinary critical care
Abstract ObjectiveTo review magnesium physiology including absorption, excretion, and function within the body, causes of magnesium abnormalities, and the current applications of magnesium monitoring and therapy in people and animals. EtiologyMagnesium plays a pivotal role in energy production and specific functions in every cell in the body. Disorders of magnesium can be correlated with severity of disease, length of hospital stay, and recovery of the septic patient. Hypermagnesemia is seen infrequently in people and animals with significant consequences reported. Hypomagnesemia is more common in critically ill people and...
Source: Journal of Veterinary Emergency and Critical Care - September 1, 2014 Category: Veterinary Research Authors: Sarah Humphrey, Rebecca Kirby, Elke Rudloff Tags: Clinical Practice Review Source Type: research

Adjuvants to local anaesthetics in regional anaesthesia – Should they be used? Part II: Cons
Publication date: August 2014 Source:Trends in Anaesthesia and Critical Care, Volume 4, Issue 4 Author(s): Ghansham Biyani , Anjolie Chhabra , Dalim Kumar Baidya Many drugs used as adjuvants for peripheral nerve blocks may not potentiate the effect of local anaesthetics to produce a clinically significant effect. At times, the side effects caused by the systemic absorption of these drugs outweigh the benefits. Some drugs that have already been in use as adjuvants have subsequently been demonstrated to have neurotoxic potential in animals, but data in humans is lacking. The aim of this article is to bring forth all the av...
Source: Trends in Anaesthesia and Critical Care - January 16, 2015 Category: Anesthesiology Source Type: research