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Drug: Aspirin

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Total 5369 results found since Jan 2013.

Pharmacological Approach to Managing Childhood-Onset Systemic Lupus Erythematosus During Conception, Pregnancy and Breastfeeding.
Abstract Pediatric patients often have poor pregnancy outcomes. Systemic lupus erythematosus predominantly impacts women in their second to fourth decade of life, with childhood-onset disease being particularly aggressive. Reproductive issues are an important clinical consideration for pediatric patients with systemic lupus erythematosus (SLE), as maintaining good disease control and planning a pregnancy are important for maternal and fetal outcomes. In this clinical review, we will consider the safety of medications in managing childhood-onset SLE during conception, pregnancy, and breastfeeding. The developing fe...
Source: Paediatric Drugs - September 3, 2018 Category: Pediatrics Authors: Bitencourt N, Bermas BL Tags: Paediatr Drugs Source Type: research

Pharmacological Approach to Managing Childhood-Onset Systemic Lupus Erythematosus During Conception, Pregnancy and Breastfeeding
AbstractPediatric patients often have poor pregnancy outcomes. Systemic lupus erythematosus predominantly impacts women in their second to fourth decade of life, with childhood-onset disease being particularly aggressive. Reproductive issues are an important clinical consideration for pediatric patients with systemic lupus erythematosus (SLE), as maintaining good disease control and planning a pregnancy are important for maternal and fetal outcomes. In this clinical review, we will consider the safety of medications in managing childhood-onset SLE during conception, pregnancy, and breastfeeding. The developing fetus is at ...
Source: Pediatric Drugs - September 3, 2018 Category: Pediatrics Source Type: research

Management of primary headaches during pregnancy, postpartum, and breastfeeding: A systematic review.
CONCLUSIONS: For prevention of primary headache, calcium channel blockers and antihistamines may not be associated with fetal/child adverse effects. For treatment, combination metoclopramide and diphenhydramine may be more effective than codeine. Triptans and low-dose aspirin may not be associated with fetal/child adverse effects. Future research should identify effective and safe interventions in pregnancy and postpartum. PMID: 33433020 [PubMed - as supplied by publisher]
Source: Headache - January 12, 2021 Category: Neurology Authors: Saldanha IJ, Cao W, Bhuma MR, Konnyu KJ, Adam GP, Mehta S, Zullo AR, Chen KK, Roth JL, Balk EM Tags: Headache Source Type: research

Diabetic Nephropathy in Women With Preexisting Diabetes: From Pregnancy Planning to Breastfeeding
Abstract In women with preexisting diabetes and nephropathy or microalbuminuria, it is important to deliver careful preconception counselling to assess the risk for the mother and the foetus, for optimizing glycaemic status and to adjust medical treatment. If serum creatinine is normal in early pregnancy, kidney function is often preserved during pregnancy, but complications such as severe preeclampsia and preterm delivery are still common. Perinatal mortality is now comparable with that in women with diabetes and normal kidney function. Besides strict glycaemic control before and during pregnancy, early and inte...
Source: Current Diabetes Reports - January 23, 2016 Category: Endocrinology Source Type: research

FDA Warns Against Use of Codeine and Tramadol in Children and Breastfeeding Women
Date: May 22, 2017 Issue #:  1521Summary:  The FDA has issued new warnings about the use of the opioid analgesics codeine and tramadol in children, particularly those<12 years old, and in breastfeeding women due to concerns about the risk of respiratory depression and death. The FDA previously issued warnings about these drugs in 2013 and 2015.
Source: The Medical Letter - May 1, 2017 Category: Drugs & Pharmacology Authors: admin Tags: Acetaminophen Aspirin Butalbital Capital carisoprodol Chlorpheniramine CoActifed Codeine ConZip Dextromethorphan Durela Fioricet Fiorinal Hydrocodone Morphine NSAIDs Ofirmev Pain Phenylephrine Promethazine pseudoeph Source Type: research

Pericarditis Management in Individuals Contemplating Pregnancy, Currently Pregnant, or Breastfeeding
AbstractPurpose of ReviewPericarditis complicates pregnancy planning, pregnancy, or the postpartum period, and the management approach requires special considerations. Here, we aim to summarize the latest research, diagnostic, and treatment strategies.Recent FindingsPhysiologic cardiovascular (CV) adaptations occurring during pregnancy complicate diagnosis, but for most patients, an electrocardiogram (ECG) and transthoracic echocardiogram (TTE) are sufficient to diagnosis pericarditis in the appropriate clinical context. Aspirin and non-steroidal anti-inflammatory drugs (NSAIDs) can be used until 20 weeks gestation as need...
Source: Current Cardiology Reports - August 26, 2023 Category: Cardiology Source Type: research

Aspirin exacerbated respiratory disease: the search for a biomarker.
PMID: 25442693 [PubMed - in process]
Source: Annals of Allergy, Asthma and Immunology - November 1, 2014 Category: Allergy & Immunology Authors: Cahill KN, Laidlaw TM Tags: Ann Allergy Asthma Immunol Source Type: research

Aspirin (single dose) for perineal pain in the early postpartum period.
CONCLUSIONS: We found low-quality evidence to suggest that single dose aspirin compared with placebo can increase pain relief in women with perineal pain post-episiotomy. Very low-quality evidence also suggested that aspirin can reduce the need for additional analgesia, without increasing maternal adverse effects. Evidence was downgraded based on study limitations (risk of bias), imprecision, and publication bias or both. RCTs excluded breastfeeding women so there is no evidence to assess the effects of aspirin on neonatal adverse effects or breastfeeding.With international guidance recommending mothers initiate breastfeed...
Source: Cochrane Database of Systematic Reviews - February 8, 2017 Category: Journals (General) Authors: Molakatalla S, Shepherd E, Grivell RM Tags: Cochrane Database Syst Rev Source Type: research

Antithrombotic therapy for ambulatory patients with multiple myeloma receiving immunomodulatory agents
CONCLUSIONS: The certainty of the available evidence for the comparative effects of ASA, VKA, LMWH, and DOAC on all-cause mortality, DVT, PE, or bleeding was either low or very low. People with multiple myeloma considering antithrombotic agents should balance the possible benefits of reduced thromboembolic complications with the possible harms and burden of anticoagulants. Editorial note: This is a living systematic review. Living systematic reviews offer a new approach to review updating in which the review is continually updated, incorporating relevant new evidence as it becomes available. Please refer to the Cochrane Da...
Source: Cochrane Database of Systematic Reviews - September 28, 2021 Category: General Medicine Authors: Lara A Kahale Charbel F Matar Ibrahim Tsolakian Maram B Hakoum Victor Ed Yosuico Irene Terrenato Francesca Sperati Maddalena Barba Lisa K Hicks Holger Sch ünemann Elie A Akl Source Type: research

Interventions for preventing thrombosis in solid organ transplant recipients
CONCLUSIONS: Overall, there is a paucity of research in the field of graft thrombosis prevention. Due to a lack of high quality evidence, it remains unclear whether any therapy is able to reduce the rate of early graft thrombosis in any type of solid organ transplant. UFH may increase the risk of major bleeding in kidney transplant recipients, however this is based on low certainty evidence. There is no evidence from RCTs to guide anti-thrombotic strategies in liver, heart, lung, or other solid organ transplants. Further studies are required in comparing anticoagulants, antiplatelets to placebo in solid organ transplantati...
Source: Cochrane Database of Systematic Reviews - March 15, 2021 Category: General Medicine Authors: Vignesh Surianarayanan Thomas J Hoather Samuel J Tingle Emily R Thompson John Hanley Colin H Wilson Source Type: research

Antithrombotic therapy for ambulatory patients with multiple myeloma receiving immunomodulatory agents
CONCLUSIONS: The certainty of the available evidence for the comparative effects of ASA, VKA, LMWH, and DOAC on all-cause mortality, DVT, PE, or bleeding was either low or very low. People with multiple myeloma considering antithrombotic agents should balance the possible benefits of reduced thromboembolic complications with the possible harms and burden of anticoagulants. Editorial note: This is a living systematic review. Living systematic reviews offer a new approach to review updating in which the review is continually updated, incorporating relevant new evidence as it becomes available. Please refer to the Cochrane Da...
Source: Cochrane Database of Systematic Reviews - September 28, 2021 Category: General Medicine Authors: Lara A Kahale Charbel F Matar Ibrahim Tsolakian Maram B Hakoum Victor Ed Yosuico Irene Terrenato Francesca Sperati Maddalena Barba Lisa K Hicks Holger Sch ünemann Elie A Akl Source Type: research

Antithrombotic therapy to prevent cognitive decline in people with small vessel disease on neuroimaging but without dementia
CONCLUSIONS: We found no convincing evidence to suggest any clinically relevant cognitive benefit of using antithrombotic therapy in addition to standard treatment in people with cerebral small vessel disease but without dementia, but there may be an increased bleeding risk with this approach. There was marked heterogeneity across the trials and the certainty of the evidence was generally poor.PMID:35833913 | PMC:PMC9281623 | DOI:10.1002/14651858.CD012269.pub2
Source: Cochrane Database of Systematic Reviews - July 14, 2022 Category: General Medicine Authors: Joseph Kwan Melanie Hafdi Lorraine L W Chiang Phyo K Myint Li Siang Wong Terry J Quinn Source Type: research