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Drug: Methotrexate
Procedure: PET Scan
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Total 206 results found since Jan 2013.
18FFDG PET-MRI provides survival biomarkers in primary central nervous system lymphoma in the elderly: an ancillary study from the BLOCAGE trial of the LOC network
CONCLUSION: Baseline cerebellar metabolism and sumMTV may predict response to end of chemotherapy in PCNSL. Tumor volume and MILAS at baseline are strong prognostic factors.PMID:37462774 | DOI:10.1007/s00259-023-06334-w
Source: Molecular Medicine - July 18, 2023 Category: Molecular Biology Authors: Laura Rozenblum Damien Galanaud Caroline Houillier Carole Soussain Amandine Baptiste Lisa Belin V éronique Edeline Philippe Naggara Marine Soret Val érie Causse-Lemercier Lise Willems Sylvain Choquet Renata Ursu Kh ê Hoang-Xuan Aur élie Kas Source Type: research
Results of a Phase II Trial of Allogeneic Hematopoietic Stem Cell Transplantation Using < sup > 90 < /sup > Y-Ibritumomab Tiuxetan (Zevalin) in Combination With Fludarabine and Melphalan in Patients With High-Risk B-Cell Non-Hodgkin's Lymphoma
CONCLUSION: Addition of Zevalin to Flu/Mel is safe and effective in high-risk NHL and met the prespecific endpoint. Results were suboptimal in patients with DLBCL.PMID:37301631 | DOI:10.1016/j.clml.2023.05.011
Source: Clinical Lymphoma and Myeloma - June 10, 2023 Category: Cancer & Oncology Authors: Matthew Mei Joycelynne Palmer Nicole Ni-Chun Tsai Jennifer Simpson James O'Hearn Anthony Stein Stephen Forman Ricardo Spielberger Ji-Lian Cai Myo Htut Ryotaro Nakamura Monzr M Al Malki Alex Herrera Jeffrey Wong Auayporn Nademanee Source Type: research
Intermittent fever and cough in a 56-year-old patient: Relapsing polychondritis and extranodal NK/T-cell lymphoma
We report a case of a 56-year-old female subject presented as intermittent fever and cough, who was found obvious luminal stenosis and intense 18F-fluorodeoxyglucose (FDG) uptake in her larynx and trachea via bronchoscopy and FDG positron emission tomography/computed tomography (PET/CT). The auricular cartilage biopsy demonstrated chondritis. At first she was diagnosed as RP and treated by glucocorticoid and methotrexate, leading to completely response. Fever and cough recurred after 18 months, and FDG PET/CT were performed again and targeted a newfound nasopharyngeal lesion, where the biopsy proved to be an extranodal nat...
Source: Cell Research - May 4, 2023 Category: Cytology Authors: Qin Huang Danyu Cui Jianhui Chen Hao Ren Min Yang Source Type: research
l-carvone decreases breast cancer cells adhesion, migration, and invasion by suppressing FAK activation
Chem Biol Interact. 2023 Apr 12:110480. doi: 10.1016/j.cbi.2023.110480. Online ahead of print.ABSTRACTBreast cancer is one of the most common types of cancer in the world and current therapeutic strategies present severe drawbacks. l-carvone (CRV), a monoterpene found in Mentha spicata (spearmint), has been reported to have potent anti-inflammatory activity. Here, we examined the role of CRV in breast cancer cell adhesion, migration and invasion in vitro and how this component could suppress the growth of Ehrlich carcinoma-bearing mice. In vivo, treatment with CRV significantly decreased tumor growth, increased tumor necro...
Source: Chemico-Biological Interactions - April 14, 2023 Category: Molecular Biology Authors: Lucas Trevisan Fran ça de Lima Fernando Augusto de Oliveira Ganzella Gabriela Casani Cardoso Ver ônica Dos Santos Pires Andressa Chequin Giulia Luiza Santos Karin Braun-Prado Claudia Martins Galindo Odair Braz Junior Marcelo Beltr ão Molento Alexandra Source Type: research
Synthesis of Zeolitic imidazolate frameworks-8@ layered double hydroxide polyhedral nanocomposite with designed porous voids as an effective carrier for anti-cancer drug-controlled delivery
IET Nanobiotechnol. 2023 Apr 6. doi: 10.1049/nbt2.12125. Online ahead of print.ABSTRACTIn nanotechnology, compounds containing metal materials are used in pharmaceutical sciences. The main purpose of this research was to introduce a novel method to control the amount of zeolite imidazolate framework (ZIF) in water by forming a protective layer such as layered double hydroxide (LDH). Firstly, ZIF was synthesised as the nucleus of the nanocomposite, and then LDH was formed by in situ synthesis as a protective layer. Scanning electron microscope, Fourier-transform infrared spectroscopy, X-Ray Diffraction, and Brunauer, Emmett...
Source: Cancer Control - April 6, 2023 Category: Cancer & Oncology Authors: Azita Dilmaghani Kamran Hosseini Vahideh Tarhriz Vahid Yousefi Source Type: research
Protective effect of methotrexate on lung function and mortality in rheumatoid arthritis-related interstitial lung disease: a retrospective cohort study
CONCLUSION: We identified risk and protective factors for lung function decline and mortality in patients with RA-ILD. MTX use was associated with favorable outcome in terms of both lung function and mortality in our cohort.PMID:36346076 | DOI:10.1177/17534666221135314
Source: Adv Data - November 8, 2022 Category: Epidemiology Authors: Kangjoon Kim Ala Woo Youngmok Park Seung Hyun Yong Su Hwan Lee Sang Hoon Lee Ah Young Leem Song Yee Kim Kyung Soo Chung Eun Young Kim Ji Ye Jung Young Ae Kang Young Sam Kim Moo Suk Park Source Type: research
Exploring the cellular uptake of hectorite clay mineral and its drug carrier capabilities
Colloids Surf B Biointerfaces. 2022 Oct 14;220:112931. doi: 10.1016/j.colsurfb.2022.112931. Online ahead of print.ABSTRACTIn the last years, the use of clay minerals for pharmaceutical purposes has increased due to their interesting properties. Hectorite (Ht) is a clay belonging to the smectite group which has attracted attention for applications in biology, tissue engineering and as drug carrier and delivery system. However, the mechanisms involved in Ht cellular uptake and transport into cells, are still unclear. Herein, we used a labeled Ht (Ht/1Cl) to study both the cellular uptake, by confocal laser scanning microscop...
Source: Colloids and Surfaces - October 20, 2022 Category: Biotechnology Authors: Monica Notarbartolo Marina Massaro Raquel de Melo Barbosa Carlotta Emili Leonarda Francesca Liotta Paola Poma Fran çisco M Raymo Rita S ànchez-Espejo Riccardo Vago C ésar Viseras-Iborra Serena Riela Source Type: research
Polymyalgia Rheumatica and Giant Cell Arteritis: Rapid Evidence Review
Am Fam Physician. 2022 Oct;106(4):420-426.ABSTRACTPolymyalgia rheumatica and giant cell arteritis are inflammatory conditions that occur predominantly in people 50 years and older, with peak incidence at 70 to 75 years of age. Polymyalgia rheumatica is more common and typically presents with constitutional symptoms, proximal muscle pain, and elevated inflammatory markers. Diagnosis of polymyalgia rheumatica is clinical, consisting of at least two weeks of proximal muscle pain, constitutional symptoms, and elevated erythrocyte sedimentation rate or C-reactive protein. Treatment of polymyalgia rheumatica includes moderate-do...
Source: Pain Physician - October 19, 2022 Category: Anesthesiology Authors: Meghan F Raleigh Jonathan Stoddard Hillary J Darrow Source Type: research
