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Total 1461 results found since Jan 2013.

Design and Rationale of the Home Blood Pressure Telemonitoring Linked with Community Health Workers to Improve Blood Pressure (LINKED-BP) Program
This study is part of the American Heart Association RESTORE (AddREssing Social Determinants TO pRevent hypErtension) Network. This study aims to examine the effect of the LINKED-BP Program on BP reduction and to evaluate the reach, adoption, sustainability, and cost-effectiveness of the intervention.METHODS: Using a hybrid type I effectiveness-implementation design, 600 adults who have elevated BP or untreated stage 1 hypertension without diabetes, chronic kidney disease, history of cardiovascular disease (stroke or coronary heart disease) and age < 65 years will be recruited from 20 primary care practices including co...
Source: American Journal of Hypertension - April 16, 2023 Category: Cardiology Authors: Yvonne Commodore-Mensah Xiaoyue Liu Oluwabunmi Ogungbe Chidinma Ibe Johnitta Amihere Margaret Mensa Seth S Martin Deidra Crews Kathryn A Carson Lisa A Cooper Cheryl R Himmelfarb Source Type: research

National Trends, Risk Factors, and Outcomes of Acute In-hospital Stroke After Lung Transplantation in the United States: Analysis of the United Network for Organ Sharing Registry
Chest. 2023 Apr 11:S0012-3692(23)00503-2. doi: 10.1016/j.chest.2023.04.007. Online ahead of print.ABSTRACTBACKGROUND: Lung transplantation is the definitive treatment for end-stage lung failure. However, there have been no large, long-term studies on the impact of acute in-hospital stroke in this population.RESEARCH QUESTION: What are the trends, risk factors, and outcomes of acute stroke in patients undergoing lung transplantation in the United States?STUDY DESIGN AND METHODS: We identified adult first-time, isolated lung transplant (LTx) recipients from the United Network for Organ Sharing (UNOS) database, which comprehe...
Source: Chest - April 13, 2023 Category: Respiratory Medicine Authors: Benjamin L Shou Christopher Wilcox Isabella Florissi Aravind Krishnan Bo Soo Kim Steven P Keller Glenn J R Whitman Ken Uchino Errol L Bush Sung-Min Cho Source Type: research

Bibliometric analysis of stroke and quality of life
ConclusionA bibliometric analysis of stroke and quality of life over the last 23  years provides future research directions.
Source: Frontiers in Neurology - April 11, 2023 Category: Neurology Source Type: research

Contemporary Antiplatelet and Anticoagulant Therapies for Secondary Stroke Prevention: A Narrative Review of Current Literature and Guidelines
AbstractPurpose of ReviewStroke is a leading cause of death and disability worldwide. The annual incidence of new or recurrent stroke is approximately 795,000 cases per year in the United States, of which 87% are ischemic in nature. In addition to the management of modifiable high-risk factors to reduce the risk of recurrent stroke, antithrombotic agents (antiplatelets and anticoagulants) play an important role in secondary stroke prevention. This review will discuss the published literature on the use of antiplatelets and anticoagulants in secondary prevention of acute ischemic stroke and transient ischemic attack (TIA), ...
Source: Current Neurology and Neuroscience Reports - April 11, 2023 Category: Neuroscience Source Type: research

ERLEADA ® (apalutamide), First-and-Only Next-Generation Androgen Receptor Inhibitor with Once-Daily, Single-Tablet Option, Now Available in the U.S.
HORSHAM, Pa., April 3, 2023 – The Janssen Pharmaceutical Companies of Johnson & Johnson today announced the availability of an additional tablet strength of ERLEADA® (apalutamide) in the United States. The introduction of the 240mg tablet provides the first-and-only option for a once-daily, single-tablet Androgen Receptor Inhibitor (ARI) approved for the treatment of patients with non-metastatic castration-resistant prostate cancer (nmCRPC) and for the treatment of patients with metastatic castration-sensitive prostate cancer (mCSPC).With two strengths available, healthcare professionals will have the flexibility to...
Source: Johnson and Johnson - April 3, 2023 Category: Pharmaceuticals Tags: Latest News Source Type: news

Global research trends on COVID-19 and stroke: A bibliometric analysis
ConclusionOur bibliometric analysis provides a comprehensive overview of the current state of research on COVID-19 and stroke and highlights key areas of focus in the field. Optimizing the treatment of COVID-19-infected stroke patients and elucidating the underlying pathogenic mechanisms of COVID-19 and stroke co-morbidity are key areas of future research that will be beneficial in improving the prognosis of stroke patients during the ongoing COVID-19 epidemic.
Source: Frontiers in Neurology - April 3, 2023 Category: Neurology Source Type: research

Vagus Nerve Stimulation Paired with Upper-Limb Rehabilitation After Stroke: Two- and Three-Year Follow-up from the Pilot Study
CONCLUSIONS: Significant effects of Paired VNS therapy at one year were maintained at years 2 and 3, and further improvements in both impairment and function were observed in years 2 and 3. These changes were associated with improvements in measures of activity and participation.PMID:37001842 | DOI:10.1016/j.apmr.2023.02.012
Source: Health Physics - March 31, 2023 Category: Physics Authors: Gerard E Francisco Navzer Engineer Jesse Dawson Teresa J Kimberley Steven Cramer Cec ília N Prudente David Pierce Brent W Tarver Reema H Adham Hinds Ann Van de Winckel Nuray Yozbatiran Source Type: research

Exploring the bi-directional relationship and shared genes between depression and stroke via NHANES and bioinformatic analysis
Conclusion: We successfully identified the ten hub shared genes linking the IS and MDD and constructed the regulatory networks for them that could serve as novel targeted therapy for the comorbidities.
Source: Frontiers in Genetics - March 31, 2023 Category: Genetics & Stem Cells Source Type: research

Associations between posttraumatic stress and stroke: A systematic review and meta ‐analysis
The objective of the present study was to systematically review the existing literature for studies examining the association between posttraumatic stress disorder (PTSD) and stroke risk and perform a meta-analysis to obtain a pooled risk estimate describing the association. A literature search was conducted in PubMed, Embase, PSYCInfo, and CINAHL to identify relevant studies. Cohort and cross-sectional studies that reported PTSD exposure (i.e., PTSD diagnosis, probable PTSD, or the presence of PTSD symptoms) at baseline and the risk or odds of stroke associated with PTSD exposure during the study period were included in t...
Source: Journal of Traumatic Stress - March 29, 2023 Category: Psychiatry & Psychology Authors: Hely D. Nanavati, Andrea Arevalo, Adeel A. Memon, Chen Lin Tags: REVIEW ARTICLE Source Type: research

Interactive Effects of Dietary Inflammatory Index with BMI for the Risk of Stroke among Adults in the United States: Insight from NHANES 2011 –2018
ConclusionsThis cross-sectional study shows that the relationship between higher DII levels and the significant increase in stroke prevalence was further amplified in patients with SBP ≥140 mmHg and higher BMI.
Source: The Journal of Nutrition, Health and Aging - March 21, 2023 Category: Nutrition Source Type: research

Study protocol of a telephone problem-solving intervention for Spanish-speaking caregivers of veterans post-stroke: an 8-session investigator-blinded, two-arm parallel (intervention vs usual care), randomized clinical trial
This study tests the impact of a telephone and online problem-solving intervention for Spanish-speaking stroke caregivers on caregiver outcomes.METHODS: The design is a two-arm parallel randomized clinical trial with repeated measures. We will enroll 290 caregivers from 3 Veterans Affairs (VA) medical centers. Participants randomized into the intervention arm receive a problem-solving intervention that uses telephone and online education and care management tools on the previously developed and nationally available RESCUE en Español Caregiver website. In the usual care group, participants receive the information and/or su...
Source: Primary Care - March 18, 2023 Category: Primary Care Authors: I Magaly Freytes Magda K Schmitzberger Naiomi Rivera-Rivera Janet Lopez Keryl Motta-Valencia Samuel S Wu Tatiana Orozco Jennifer Hale-Gallardo Nathaniel Eliazar-Macke Jennifer H LeLaurin Constance R Uphold Source Type: research