Filtered By:
Specialty: Cardiology
Countries: UK Health

This page shows you your search results in order of date.

Order by Relevance | Date

Total 23 results found since Jan 2013.

Endocan is Related to Increased Cardiovascular Risk in Type 2 Diabetes Mellitus Patients
Conclusion: Endocan was the independent predictor for moderate and high estimated risks (i.e., nonfatal and fatal CHD and nonfatal stroke risk scores) in T2D patients. When included in models with sex and obesity indices endocan demonstrated good clinical accuracy in discriminating T2D patients with high risk for nonfatal and fatal eCHD and nonfatal stroke risk from those patients with low risk.PMID:37279462 | DOI:10.1089/met.2023.0050
Source: Atherosclerosis - June 6, 2023 Category: Cardiology Authors: Aleksandra Klisic Jelena Kotur-Stevuljevic Ana Ninic Source Type: research

Associations of genetically predicted IL-6 signaling with cardiovascular disease risk across population subgroups
CONCLUSIONS: Any benefit of inhibiting IL-6 signaling for CVD risk reduction is likely to be proportional to absolute reductions in hsCRP levels. Therapeutic inhibition of IL-6 signaling for CVD risk reduction should therefore prioritize those individuals with the highest baseline levels of hsCRP.PMID:35948913 | DOI:10.1186/s12916-022-02446-6
Source: Atherosclerosis - August 10, 2022 Category: Cardiology Authors: Marios K Georgakis Rainer Malik Tom G Richardson Joanna M M Howson Christopher D Anderson Stephen Burgess G Kees Hovingh Martin Dichgans Dipender Gill Source Type: research

Air pollution and cardiovascular disease: the Paul Wood Lecture, British Cardiovascular Society 2021
Air pollution is associated with up to 8.8 million excess deaths worldwide each year and is a major contributor to the global burden of disease. Cardiovascular conditions are the predominant cause for air pollution-related deaths and there is an urgent need to address the silent pandemic of air pollution on cardiovascular health. Air pollution exposure is associated with acute events like acute coronary syndrome and stroke, and with chronic conditions, such as atherosclerosis and heart failure. Several potential mechanisms have been proposed that link particle inhalation to cardiovascular disease including oxidative stress...
Source: Heart - July 27, 2022 Category: Cardiology Authors: Joshi, S. S., Miller, M. R., Newby, D. E. Tags: Review articles Reviews Source Type: research

Can Interventional Cardiologists Help Deliver the UK Mechanical Thrombectomy Interventional Programme for Patients with Acute Ischaemic Stroke? A Discussion Paper from the British Cardiovascular Interventional Society Stroke Thrombectomy Focus Group
Discussion Paper from the British Cardiovascular Interventional Society Stroke Thrombectomy Focus Group The Challenge Only 2% of ischaemic stroke patients in the UK receive emergency interventional thrombectomy treatment.1 More than 7,000 eligible patients each year are unable to access a therapy ...
Source: Radcliffe Cardiology - June 9, 2022 Category: Cardiology Authors: c242508f1d9059bc0f2aa9bdd5421ba2 Source Type: research

Air pollution and cardiovascular disease: the Paul Wood Lecture, British Cardiovascular Society 2021
Heart. 2022 Jan 24:heartjnl-2021-319844. doi: 10.1136/heartjnl-2021-319844. Online ahead of print.ABSTRACTAir pollution is associated with up to 8.8 million excess deaths worldwide each year and is a major contributor to the global burden of disease. Cardiovascular conditions are the predominant cause for air pollution-related deaths and there is an urgent need to address the silent pandemic of air pollution on cardiovascular health. Air pollution exposure is associated with acute events like acute coronary syndrome and stroke, and with chronic conditions, such as atherosclerosis and heart failure. Several potential mechan...
Source: Atherosclerosis - January 25, 2022 Category: Cardiology Authors: Shruti S Joshi Mark R Miller David E Newby Source Type: research

Additive Effects of Genetic Interleukin-6 Signaling Downregulation and Low-Density Lipoprotein Cholesterol Lowering on Cardiovascular Disease: A 2 ×2 Factorial Mendelian Randomization Analysis
Conclusions Genetically downregulated IL-6 signaling and genetically lowered LDL-C are associated with additively lower lifetime risk of cardiovascular disease. Future trials should explore combined IL-6 inhibition and LDL-C lowering treatments for cardiovascular prevention.PMID:34927447 | DOI:10.1161/JAHA.121.023277
Source: Atherosclerosis - December 20, 2021 Category: Cardiology Authors: Marios K Georgakis Rainer Malik Stephen Burgess Martin Dichgans Source Type: research

Drug overdose and the risk of cardiovascular diseases: a nested case –control study
ConclusionsDrug overdose appears to be associated with increased risk of cardiovascular diseases.Graphic abstract
Source: Clinical Research in Cardiology - October 15, 2021 Category: Cardiology Source Type: research

Age-Stratified Outcome in Treatment of Left Main Coronary Artery Stenosis: A NOBLE Trial Substudy
Conclusions: As the overall NOBLE results show revascularization of LMCA disease, age of 67 years or older was associated with lower 5-year MACCE after CABG compared to PCI. Clinical outcomes were not significantly different in the subgroup younger than 67 years, although no significant interaction was present between age and treatment. Mortality was similar for all subgroups (ClinicalTrials.gov identifier: NCT01496651).Cardiology
Source: Cardiology - April 13, 2021 Category: Cardiology Source Type: research

Outcomes of Percutaneous Coronary Intervention in Cardiac Transplant Patients: A Binational Analysis Derived From the United Kingdom and United States.
CONCLUSIONS: PCI in cardiac transplant recipients was associated with similar short-term mortality and vascular complications compared with PCI in the general populace. However, a higher 1-year morality was observed in the BCIS cohort. PMID: 32865507 [PubMed - in process]
Source: The Journal of Invasive Cardiology - September 2, 2020 Category: Cardiology Tags: J Invasive Cardiol Source Type: research

Clinical Outcomes of Percutaneous Coronary Intervention for Chronic Total Occlusion in Native Coronary Arteries vs Saphenous Vein Grafts.
CONCLUSION: In this national cohort, CTO-PCI was performed in higher-risk patients, and was associated with more procedural complications but similar short-term or long-term mortality and in-hospital MACE. PMID: 32771995 [PubMed - as supplied by publisher]
Source: The Journal of Invasive Cardiology - August 13, 2020 Category: Cardiology Tags: J Invasive Cardiol Source Type: research

Substantial Cardiovascular Morbidity in Adults with Lower-Complexity Congenital Heart Disease.
CONCLUSIONS: Individuals with lower-complexity ACHD had higher burden of adverse cardiovascular events relative to the general population that was unaccounted for by conventional cardiovascular risk factors. These findings highlight the need for closer surveillance of patients with mild to moderate ACHD and further investigation into management and mechanisms of cardiovascular risk unique to this growing population of high-risk adults. PMID: 30813762 [PubMed - as supplied by publisher]
Source: Circulation - February 27, 2019 Category: Cardiology Authors: Saha P, Potiny P, Rigdon J, Morello M, Tcheandjieu C, Romfh A, Fernandes SM, McElhinney DB, Bernstein D, Lui GK, Shaw GM, Ingelsson E, Priest JR Tags: Circulation Source Type: research

Design and rationale of the Edoxaban Treatment in routiNe clinical prActice for patients with Atrial Fibrillation in Europe (ETNA-AF-Europe) study
This study details the design of the Edoxaban Treatment in routiNe clinical prActice for patients with Atrial Fibrillation in Europe (ETNA-AF-Europe) study – a postauthorization observational study, which is part of the postapproval plan for edoxaban agreed with the European Medicines Agency. Methods The ETNA-AF-Europe study (Clinicaltrials.gov: NCT02944019) is a multicenter, prospective, observational study that enrolled 13 980 patients with atrial fibrillation treated with edoxaban from 852 sites across 10 European countries (Austria, Belgium, Germany, Ireland, Italy, the Netherlands, Portugal, Spain, Switzerland,...
Source: Journal of Cardiovascular Medicine - January 3, 2019 Category: Cardiology Tags: Research articles: Trial design Source Type: research

Patients ’ Priorities for Oral Anticoagulation Therapy in Non-valvular Atrial Fibrillation: a Multi-criteria Decision Analysis
DiscussionAlthough the relative impact of convenience on therapy value is small, patients have different preferences for options within convenience criteria. Besides considerations on safety and effectiveness, physicians should also discuss attributes of convenience with patients, as it can be assumed that alignment to patient preferences in drug prescription and better patient education could result in higher adherence.
Source: American Journal of Cardiovascular Drugs - August 22, 2018 Category: Cardiology Source Type: research