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PROCAM based myocardial infarction risk in relation to global vascular disease risk: observations from the ARCO cohort study
CONCLUSIONS: PROCAM-derived risk calculators are well calibrated for the risk of AMI. PROCAM-AMI should be multiplied by a factor of 4 to obtain ASCVD. PROCAM-AMI does not represent global cardiovascular risk. Corresponding adjustments in the AGLA communication of risk appear necessary.PMID:35201684 | DOI:10.4414/smw.2022.w30111
Source: Swiss Medical Weekly - February 24, 2022 Category: General Medicine Authors: Michel Romanens Ansgar Adams Walter Warmuth Source Type: research

Diagnostic reference levels and median doses for common clinical indications of CT: findings from an international registry
ConclusionsDRLs for CTDIvol and DLP for EUCLID clinical indications from diverse organizations were established and can contribute to dose optimization. These values were usually significantly higher in the US than in Europe.Key Points•Registry data were used to create benchmarks for 10 common indications for CT identified by the European Society of Radiology.•Observed US radiation doses were higher than European for 9 of 10 indications (except chronic sinusitis).•The presented diagnostic reference levels and median doses highlight potentially unnecessary variation in radiation dose.
Source: European Radiology - October 13, 2021 Category: Radiology Source Type: research

EP35 7 T MR imaging of small incidental unruptured intracranial aneurysms: first year of clinical experience
ConclusionsClinical implementation of 7 T MRI in patients with suspected small incidental UIAs has the potential to reduce the number of ambiguous vascular findings, secure the diagnosis, reduce the invasive imaging work-up and has therefore an impact on patient management.ReferencesOkahara M, et al. Diagnostic accuracy of magnetic resonance angiography for cerebral aneurysms in correlation with 3D-digital subtraction angiographic images: a study of 133 aneurysms. Stroke 2002;33(7):1803–8.Li MH, et al. Accurate diagnosis of small cerebral aneurysms ≤5 mm in diameter with 3.0-T MR angiography. Radiology 2014;271(2)...
Source: Journal of NeuroInterventional Surgery - August 24, 2021 Category: Neurosurgery Authors: Radojewski, P., Slotboom, J., Joseph, A., Bonanno, G., Dobrocky, T., Bervini, D., Raabe, A., Wiest, R., Gralla, J., Mordasini, P. Tags: Miscellaneous Source Type: research

Validation of the focal cerebral arteriopathy severity score (FCASS) in a Swiss cohort: Correlation with infarct volume and outcome.
CONCLUSIONS: In this independent validation cohort, higher maximum FCASS correlated with greater infarct volume scores that also correlated with worse neurological outcomes. Scoring by non-imaging specialists seems to be valuable, although differences are present. PMID: 32826156 [PubMed - as supplied by publisher]
Source: European Journal of Paediatric Neurology - August 3, 2020 Category: Neurology Authors: Slavova N, Fullerton HJ, Hills NK, Breiding PS, Mackay MT, Steinlin M Tags: Eur J Paediatr Neurol Source Type: research

Surgical decision-making depending solely on the radiological volume of the ischemic brain can be misleading in the management of patients with malignant stroke
Publication date: June 2020Source: Interdisciplinary Neurosurgery, Volume 20Author(s): Baha Eldin Adam, Emin Mehmet Eminoglu, Zeynep Karaoglu, Naci BalakAbstractRecent studies suggest that a total ischemic brain tissue volume>300 cm3 observed on CT is a significant indicator of an unfavorable outcome with a sensitivity of 100% after DC in patients with malignant ischemic stroke. In this article, we reported a 61-year-old male patient with poor preoperative clinical status and most predictive factors pointed to an unfavorable outcome who nonetheless demonstrated an acceptable functional recovery after DC. On cranial comput...
Source: Interdisciplinary Neurosurgery - January 28, 2020 Category: Neurosurgery Source Type: research

Correlation Between Intracranial Arterial Calcification and Imaging of Cerebral Small Vessel Disease
Conclusion: Intracranial artery calcification is common in patients with ischemic cerebrovascular disease and the intracranial carotid artery is most frequently affected. Intracranial arterial calcifications might be associated with imaging markers of SVD and are highly correlated with WMHs, lacunes, and CMBs. Quantification of calcification on CT provides additional information on the pathophysiology of SVD. Intracranial arterial calcification could act as a potential marker of SVD. Introduction Atherosclerosis is a systemic vascular process that is considered a major cause of cerebrovascular and cardiovascular di...
Source: Frontiers in Neurology - April 30, 2019 Category: Neurology Source Type: research

Intravenous Thrombolysis in Posterior Circulation Stroke
Conclusions: Up to date, no data about PCIS and IVT are available from RTCs. Based on limited results from retrospective clinical studies and case series, IVT is safer for use in PCIS than in ACIS. Patients with brainstem ischemia, vertebral artery occlusion, and absence of basilar or posterior cerebral artery occlusion could be considered for treatment with IVT even in borderline cases. Time to IVT in PCIS seems to be a less crucial factor than in ACIS. IVT for PCIS may be beneficial even after 4.5 h from symptom onset. Introduction History of Intravenous Thrombolysis—The Most Relevant Studies Intravenous...
Source: Frontiers in Neurology - April 25, 2019 Category: Neurology Source Type: research

Propensity Score-Matched Analysis of Lesion Patterns in Stroke Patients With Patent Foramen Ovale and Patients With Spontaneous Intracranial Artery Dissection
Conclusion: The present study suggests that lesion patterns observed from DWI of patients with PFO and SIAD might provide clues to the etiology of infarcts. Single lesions (cortical or subcortical) might be a typical feature of PFO associated strokes, while multiple lesions in one vascular territory might be a specific feature of SIAD associated strokes. Introduction Both patent foramen ovale (PFO) and spontaneous intracranial artery dissection (SIAD) are important stroke risk factors, especially in young and middle-aged adults (1–3). About 25% of patients with ischemic stroke are cryptogenic (4), and PFO is ...
Source: Frontiers in Neurology - April 23, 2019 Category: Neurology Source Type: research

Conveniently-Grasped Field Assessment Stroke Triage (CG-FAST): A Modified Scale to Detect Large Vessel Occlusion Stroke
Conclusions: CG-FAST scale could be an effective and simple scale for accurate identification of LVOS among AIS patients. Introduction Large vessel occlusion stroke (LVOS) often leads to severe disability and mortality. Although endovascular therapy (EVT) has been proved to be effective for LVOS patients (1–9), especially in anterior circulation, its benefit is highly time-dependent (10, 11). As hospitals with around-the-clock endovascular capability are scarce in many parts of the world and patients admitted directly to a CSC would have better outcomes than those receiving drip and ship treatment (12, 13), t...
Source: Frontiers in Neurology - April 16, 2019 Category: Neurology Source Type: research

Stenosis Length and Degree Interact With the Risk of Cerebrovascular Events Related to Internal Carotid Artery Stenosis
Conclusion: We found a statistically insignificant tendency for the ultrasound-measured length of sICAS<70% to be longer than that of sICAS≥70%. Moreover, the ultrasound-measured length of sICAS<90% was significantly longer than that of sICAS 90%. Among patients with sICAS≥70%, the degree and length of stenosis were inversely correlated. Larger studies are needed before a clinical implication can be drawn from these results. Introduction Internal carotid artery stenosis (ICAS) causes around one-fifth of ischemic cerebrovascular stroke and has the highest risk of early stroke recurrence...
Source: Frontiers in Neurology - April 8, 2019 Category: Neurology Source Type: research

In-vivo phase contrast magnetic resonance angiography of the cerebrovascular system: a comparative study with duplex sonography.
CONCLUSION: PC-MRA represents a robust, standardised magnetic resonance imaging technique for blood flow measurements within a reasonable acquisition time, potentially evolving as valuable work-up tool for more precise patient stratification for revascularisation therapy. PC-MRA overcomes relevant weaknesses of CCD in being not operator-dependent and not relying on a bone window to assess the intracranial arteries. PMID: 26151805 [PubMed - in process]
Source: Swiss Medical Weekly - July 14, 2015 Category: Journals (General) Authors: Hsieh K, Stein K, Mono ML, Kellner-Weldon F, Verma RK, Weisstanner C, Andereggen L, Reinert M, Gralla J, Schroth G, El-Koussy M Tags: Swiss Med Wkly Source Type: research