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Total 456 results found since Jan 2013.

Age- and Weight-Adapted Dose of Prasugrel Versus Standard Dose of Ticagrelor in Patients With Acute Coronary Syndromes: Results From a Randomized Trial.
CONCLUSION: In elderly or low-weight patients with ACS, a reduced dose of prasugrel compared with the standard dose of ticagrelor is associated with maintained anti-ischemic efficacy while protecting these patients against the excess risk for bleeding. PRIMARY FUNDING SOURCE: German Center for Cardiovascular Research and Deutsches Herzzentrum München. PMID: 32687741 [PubMed - as supplied by publisher]
Source: Annals of Internal Medicine - July 20, 2020 Category: Internal Medicine Authors: Menichelli M, Neumann FJ, Ndrepepa G, Mayer K, Wöhrle J, Bernlochner I, Richardt G, Witzenbichler B, Sibbing D, Gewalt S, Angiolillo DJ, Lahu S, Hamm CW, Hapfelmeier A, Trenk D, Laugwitz KL, Schunkert H, Schüpke S, Kastrati A Tags: Ann Intern Med Source Type: research

IJERPH, Vol. 17, Pages 5233: Return to Work and Quality of Life after Stroke in Italy: A Study on the Efficacy of Technologically Assisted Neurorehabilitation
olucci Marco Iosa Cerebrovascular diseases, including stroke, are historically considered diseases of old adults so only in a few studies has “return to work” (RTW) been considered as an index of rehabilitative outcome. At the moment, data on RTW in patients with stroke are highly variable: four different reviews reported the following ranges: 11–85%, 19–73%, 22–53%, and 40–45%. The absence of re-integration to work after a stroke is shown to be associated with an increase of cardiac disorders and depression, with a higher level of mo...
Source: International Journal of Environmental Research and Public Health - July 19, 2020 Category: Environmental Health Authors: Sheyda Ghanbari Ghoshchi Sara De Angelis Giovanni Morone Monica Panigazzi Benedetta Persechino Marco Tramontano Edda Capodaglio Pierluigi Zoccolotti Stefano Paolucci Marco Iosa Tags: Article Source Type: research

Feasibility and value of two-dimensional volumetric stress echocardiography.
CONCLUSIONS: Volumetric SE is highly feasible with all stresses, and more frequently impaired in presence of ischemic RWMA, absence of viability and reduced coronary flow velocity reserve. It identifies an altered stroke volume response due to reduced preload and/or contractile reserve. PMID: 32657562 [PubMed - as supplied by publisher]
Source: Minerva Cardioangiologica - July 14, 2020 Category: Cardiology Tags: Minerva Cardioangiol Source Type: research

Effect of lockdown on the management of ischemic stroke: an Italian experience from a COVID hospital
ConclusionsDue to the COVID-19 pandemic and lockdown measures, the stroke care pathway changed, involving both pre-hospital and in-hospital performances.
Source: Neurological Sciences - July 5, 2020 Category: Neurology Source Type: research

Neurologic aspects of covid-19: a concise review.
In conclusion, nervous system symptoms can be observed during SARS-CoV2 infection of which headache and smell and taste disturbance are the main symptoms reported. Cerebrovascular complications can complicate the course of COVID-19 in apparently low-risk patients. GBS is a life-threatening manifestation of COVID-19. PMID: 32532937 [PubMed - as supplied by publisher]
Source: Infezioni in Medicina - June 14, 2020 Category: Infectious Diseases Tags: Infez Med Source Type: research

Healthy People Shouldn ’ t Take Daily Aspirin To Prevent Heart Disease, Review Finds
(CNN) — Still taking a daily aspirin to ward off heart attacks? You might want to think again, according to a new review. Aspirin is still one of the most commonly used medications in the world, even though it’s no longer recommended as a preventative by many health authorities. There is no evidence that low-dose aspirin — less than 325 milligrams a day — should be taken by most adults in good cardiovascular health, according to a new review of existing research that published Wednesday in the British Journal of Clinical Pharmacology. The review, which focused on the risks and benefits of low-dose daily asp...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - June 3, 2020 Category: Consumer Health News Authors: Health – CBS Boston Tags: Health News aspirin CNN Source Type: news

Spirituality Helps Stroke Survivors, Caregivers Bounce Back
THURSDAY, May 28, 2020 -- Could a higher power help stroke recovery? People who are spiritual may be better able to deal with stroke-related disability, new research suggests. The Italian study linked spirituality -- be it through religion or...
Source: Drugs.com - Daily MedNews - May 28, 2020 Category: General Medicine Source Type: news

Design and rationale of a randomized, placebo-controlled trial on the efficacy and safety of sulodexide for extended treatment in elderly patients after a first venous thromboembolism
AbstractHow to prevent recurrences after a first venous thromboembolic (VTE) event in elderly patients is still an open issue, especially because of the high bleeding risk of anticoagulation in these patients. The placebo-controlled “Jason” study aims at assessing the efficacy and safety for secondary VTE prevention in elderly patients of oral Sulodexide (Vessel®) administration, a mixture of glycosaminoglycans (Alfasigma, Bologna, Italy) which proved effective against recurrences in a general population (SURVET study) without major bleeding (MB) complications. 1450 patients, aged  ≥ 75 years, after at least 3...
Source: Internal and Emergency Medicine - May 24, 2020 Category: Emergency Medicine Source Type: research

Age at death in elderly cohorts of four European countries of the Seven Countries Study: the role of comorbidities.
CONCLUSION: AD seems a valuable indicator of all-cause mortality when the study population has reached or approached the extinction. PMID: 32410168 [PubMed - as supplied by publisher]
Source: Aging Clinical and Experimental Research - May 13, 2020 Category: Geriatrics Authors: Menotti A, Puddu PE, Tolonen H Tags: Aging Clin Exp Res Source Type: research

Long-term outcome of cervical artery dissection
AbstractLong-term consequences of cervical artery dissection (CeAD), a major cause of ischemic stroke in young people, have been poorly investigated. The Italian Project on Stroke at Young Age – Cervical Artery Dissection (IPSYS CeAD) project is a multicenter, hospital-based, consecutively recruiting, observational, cohort study aimed to address clinically important questions about long-term outcome of CeAD patients, which are not covered by other large-scale registries. Patients with r adiologically diagnosed CeAD were consecutively included in the registry. Baseline demographic and clinical variables, as well as inform...
Source: Neurological Sciences - May 11, 2020 Category: Neurology Source Type: research

Clinical RoPE (cRoPE) score predicts patent foramen ovale detection among stroke patients: a multicenter observational study
ConclusionsConclusions:  cRoPE might help in stratification of patients with CS, allowing accurate esteem of the likelihood of PFO to be found, especially in cases when neuroimaging is inconclusive.
Source: Neurological Sciences - May 8, 2020 Category: Neurology Source Type: research

Transcultural translation and validation of Fugl-Meyer assessment to Italian.
Conclusions: The culturally validated Italian Fugl-Meyer Assessment can reliably be used in research and in clinical practice. A standardized use will improve the quality of sensorimotor assessment in stroke across Italy and allow reliable comparisons of stroke populations internationally.Implications for rehabilitationThe Fugl-Meyer Assessment is the gold standard for evaluation of sensorimotor impairment after stroke.Having access to a transculturally validated official Italian version of Fugl-Meyer Assessment will improve the quality of sensorimotor assessment after stroke among Italian health professionals and research...
Source: Disability and Rehabilitation - April 30, 2020 Category: Rehabilitation Authors: Cecchi F, Carrabba C, Bertolucci F, Castagnoli C, Falsini C, Gnetti B, Hochleitner I, Lucidi G, Martini M, Mosca IE, Pancani S, Paperini A, Verdesca S, Macchi C, Alt Murphy M Tags: Disabil Rehabil Source Type: research

The management of patients with acute ischemic stroke while on direct oral anticoagulants (DOACs): data from an Italian cohort and a proposed algorithm
This study aimed at investigating whether there is any relationship between DOAC plasma levels and the stroke occurrence, on the basis of the phenotypic classification and pathophysiology of the stroke, in a cohort of DOAC-treated patients admitted to our hospital for AIS o ver 1-year period. A total of 28 patients had DOAC plasma levels determined in emergency and were included in the study, nine patients receiving dabigatran, 11 rivaroxaban and 8 apixaban. The DOAC levels were low in 8/28 patients (28.6% of the sample), intermediate in 4 (14.3%) and high in 16 (57.1% ). The most prevalent stroke subtype was the small ves...
Source: Journal of Thrombosis and Thrombolysis - April 16, 2020 Category: Hematology Source Type: research

Concern as heart attack and stroke patients delay seeking help
Consultants report drop in admissions of people with non-coronavirus related conditionsCoronavirus – latest updatesSee all our coronavirus coverageFurther evidence is emerging of dramatic falls in numbers of hospital patients presenting with serious medical conditions such as strokes and heart attacks since the beginning of the coronavirus pandemic.AUS study found that interventions for serious heart attacks have fallen 38% since 1 March. Similar reductions were reported in Spain, while inLombardy, the worst affected region of Italy, the figure was 70%.Continue reading...
Source: Guardian Unlimited Science - April 16, 2020 Category: Science Authors: Laura Spinney Tags: Coronavirus outbreak Hospitals Doctors Health Medical research Science Society Heart disease Heart attack Stroke World news UK news Source Type: news

SMASH-U classification: a tool for aetiology-oriented management of patients with acute haemorrhagic stroke
AbstractIntracerebral haemorrhage (ICH) is responsible for disproportionately high morbidity and mortality rates. The most used ICH classification system is based on the anatomical site. We used SMASH-U, an aetiological based classification system for ICH by predefined criteria: structural vascular lesions (S), medication (M), amyloid angiopathy (A), systemic disease (S), hypertension (H), or undetermined (U). We aimed to correlate SMASH-U classification of our patients to the intra-hospital mortality rates. We performed a single centre retrospective study at the Santa Maria Della Misericordia Hospital, Perugia (Italy) inc...
Source: Internal and Emergency Medicine - April 7, 2020 Category: Emergency Medicine Source Type: research