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Total 900 results found since Jan 2013.

Feasibility of platelet marker analysis in ischemic stroke patients and their association with one-year outcome. A pilot project within a subsample of the Stroke Induced Cardiac Failure in Mice and Men (SICFAIL) cohort study
Platelets. 2021 Dec 7:1-9. doi: 10.1080/09537104.2021.2002834. Online ahead of print.ABSTRACTPatients with ischemic stroke (IS) are at increased risk of mortality and recurrent cerebro- or cardiovascular events. Determining prognosis after IS remains challenging but blood-based biomarkers might provide additional prognostic information. As platelets are crucially involved in the pathophysiology of vascular diseases, platelet surface proteins (PSP) are promising candidates as prognostic markers in the hyperacute stage. In this pilot study, feasibility of PSP analysis by flow cytometry (HMGB1, CD84, CXCR4, CXCR7, CD62p with ...
Source: Platelets - December 8, 2021 Category: Hematology Authors: Mert Seyhan Kathrin Ungeth üm Michael K Schuhmann Daniel Mackenrodt Viktoria R ücker Felipe A Montellano Silke Wiedmann Dominik Rath Tobias Geisler Bernhard Nieswandt Peter Kraft Christoph Kleinschnitz Peter U Heuschmann Source Type: research

Patient Pathways During Acute in-Hospital Stroke Treatment: A Qualitative Multi-Method Study
Discussion:Our results show that most direct staff-patient interactions are focussed within one phase, with a smaller number of interactions extending to other phases, and no professional (group) with direct patient interactions cover more than two phases of the acute stroke pathway. Future research should investigate how the pathways described here are experienced from the patient perspective, including how the organisation of visible care processes may influence patient satisfaction. Findings can be translated to accessible patient information resources as well as input for digitalisation efforts, provider orientation an...
Source: International Journal of Integrated Care - February 21, 2022 Category: Nursing Source Type: research

Point of Care Assessment of Direct Oral Anticoagulation in Acute Ischemic Stroke: Protocol for a Prospective Observational Diagnostic Accuracy Study
This study will test the hypothesis that hyperacute point-of-care assessment of clotting time in the patient's whole blood has sufficient diagnostic accuracy to determine immediately whether stroke patients are pretreated with DOAC. Methods/ Design: This will be a prospective single-center diagnostic accuracy study in 1850 consecutive acute ischemic stroke patients at a tertiary stroke center in Saxony, Germany. Presence of active anticoagulation with DOAC will be determined by point-of-care quantification of clotting time via whole blood viscoelastic testing (ClotPro®) using Russell venom viper and Ecarin assay compared ...
Source: Thrombosis and Haemostasis - June 7, 2022 Category: Hematology Authors: Annahita Sedghi Lars Heubner Anna Klimova Oliver Tiebel J örg Pietsch Martin Mirus Kristian Barlinn Tabea Tabita Talita Tatjana Minx Jan Beyer-Westendorf Volker Puetz Peter Spieth Timo Siepmann Source Type: research

Tailored GuideLine Implementation in STrokE Rehabilitation (GLISTER) in Germany. Protocol of a Mixed Methods Study Using the Behavior Change Wheel and the Theoretical Domains Framework
ConclusionThis will be the first endeavor to implement a guideline in German stroke rehabilitation with a focus on changing care provider behavior based on the knowledge of current practice and determining factors using a tailored and theory-based intervention.
Source: Frontiers in Neurology - July 27, 2022 Category: Neurology Source Type: research

A study of the correlation between stroke and gut microbiota over the last 20years: a bibliometric analysis
ConclusionFindings suggest that in the next 10 years, the number of publications produced annually may increase significantly. Future research trends tend to concentrate on the mechanisms of stroke and gut microbiota, with the inflammation and immunological mechanisms, TMAO, and fecal transplantation as hotspots. And the relationship between these mechanisms and a particular cardiovascular illness may also be a future research trend.
Source: Frontiers in Microbiology - June 7, 2023 Category: Microbiology Source Type: research

Participation after stroke: the influence of depression in outpatient neurological rehabilitation.
DISCUSSION: A relationship between depressiveness and participation was shown. The treatment of depressive symptoms through timely administered psychotherapeutic and medicinal care and general activity promotion could influence the participation in a beneficial way. PMID: 30238233 [PubMed - as supplied by publisher]
Source: Der Nervenarzt - September 20, 2018 Category: Neurology Authors: Marheineke J, Deck R, Reuther P, Pöppl D, Theves F, Kohlmann T Tags: Nervenarzt Source Type: research

Long-term health benefits of stroke prevention with apixaban versus vitamin K antagonist warfarin in patients with non-valvular atrial fibrillation in Germany: a population-based modelling study.
CONCLUSION: This study demonstrated that using apixaban instead of VKA for stroke prevention can lead to considerable reduction in cardiovascular events. PMID: 30295561 [PubMed - as supplied by publisher]
Source: Expert Review of Pharmacoeconomics and Outcomes Research - October 10, 2018 Category: Health Management Tags: Expert Rev Pharmacoecon Outcomes Res Source Type: research

Hypertrophic olivary degeneration : Cause of new neurological symptoms after stroke.
CONCLUSION: Analysis of the dataset provided confirmation of the results in the literature that lesions within the Guillain-Mollaret triangle more often lead to HOD. Patients with corresponding symptoms should be closely observed over time with respect to the occurrence of corresponding clinical and imaging leading symptoms. Even though the named clinical symptoms are characteristic for HOD, in many cases the diagnosis is hampered and delayed by imprecise examination and misinterpretation of the symptoms. A logopedic examination using FEES in this collective often provided indicative information. Currently, no reliable dat...
Source: Der Nervenarzt - November 28, 2018 Category: Neurology Authors: Foerch C, Schaller MA, Lapa S, Filipski K, Steinmetz H, Kang JS, Zöllner JP, Wagner M Tags: Nervenarzt Source Type: research

Fast treatment via mobile stroke unit reduced survivor disability
(American Heart Association) Stroke patients were more likely to get clot-busting treatment and received it faster if treatment started in a mobile stroke unit, an ambulance specially equipped to provide treatment.Those treated in a mobile stroke unit had less post-stroke disability, a German study found.
Source: EurekAlert! - Medicine and Health - February 20, 2020 Category: International Medicine & Public Health Source Type: news

Task-Oriented Circuit Training for Mobility in Outpatient Stroke Rehabilitation in Germany and Austria: A Contextual Transferability Analysis.
Abstract People with stroke cite mobility deficits as one of the most burdensome limitations. National and international stroke guidelines recommend physical therapy based on task-oriented practice, with high numbers of repetitions to improve mobility. In the outpatient setting in Germany and Austria, these principles have not yet been established. The purpose of this study was to identify an evidence-based intervention that could help reduce this research-practice gap. A stepwise approach proposed by Voigt-Radloff et al and Cochrane Germany was used. First, the specific health service problem in the German and Au...
Source: Physical Therapy - April 6, 2020 Category: Physiotherapy Authors: Diermayr G, Schomberg M, Greisberger A, Elsner B, Gronwald M, Salbach NM Tags: Phys Ther Source Type: research

Inhouse Bridging Thrombolysis Is Associated With Improved Functional Outcome in Patients With Large Vessel Occlusion Stroke: Findings From the German Stroke Registry
Conclusions: This study provides evidence that bridging IVT might improve rates of successful reperfusion and long-term functional outcome in mothership patients with anterior circulation LVOS eligible for EVT.
Source: Frontiers in Neurology - June 10, 2021 Category: Neurology Source Type: research

Predicting the risk of stroke in patients with late-onset epilepsy: A machine learning approach
CONCLUSION: The stroke risk in patients with epilepsy was relatively high and could be predicted based on comorbidities such as diabetes mellitus, hypertension, heart failure, and alcohol dependence. Knowing and addressing these factors may help reduce the risk of stroke in patients with epilepsy.PMID:34325155 | DOI:10.1016/j.yebeh.2021.108211
Source: Epilepsy and Behaviour - July 29, 2021 Category: Neurology Authors: Karel Kostev Tong Wu Yue Wang Kal Chaudhuri Christian Tanislav Source Type: research