• Filter By:
• Specialty
• Source
• Condition
• Cancer
• Infectious Disease
• Drug
• Training
• Management
• Procedure
• Therapy
• Vaccine
• Nutrition
• Country

Global trends and hotspots in research on acupuncture for stroke: a bibliometric and visualization analysis
This study aimed to characterize the global publications and analyze the trends of acupuncture for stroke in the past 40  years. We identified 1157 publications from the Web of Science Core Collection. The number of publications grew slowly in the first three decades from 1980 until it started to grow after 2010, with significant growth in 2011–2012 and 2019–2020. China, the USA, and South Korea are the top three countries in this field, and China has formed good internal cooperative relations. Early studies focused on the clinical efficacy of acupuncture for stroke. In the last five years, more emphasis has been plac...
Source: European Journal of Medical Research - September 21, 2023 Category: Research Source Type: research

Network pharmacology and molecular docking analysis on molecular targets and mechanisms of < em > Gastrodia  elata < /em > Blume in the treatment of ischemic stroke
Exp Ther Med. 2022 Nov 3;24(6):742. doi: 10.3892/etm.2022.11678. eCollection 2022 Dec.ABSTRACTGastrodia elata Blume (GEB) is widely used to treat cardio-cerebrovascular disease in China and in traditional Chinese medicine it is considered to be a dispelling wind and dredging collateral. However, the mechanism and active components of the plant in treating ischemic stroke (IS) remain unclear. The present study aimed to identify the active components and mechanism of GEB in treating IS using network pharmacology and molecular docking technology. Network analysis predicted 752 potential targets from 14 compounds in GEB, shari...
Source: Experimental and Therapeutic Medicine - December 26, 2022 Category: General Medicine Authors: Yuan Luo Pu Chen Liping Yang Xiaohua Duan Source Type: research

Efficacy of Balloon Guide Catheter-Assisted Thrombus Repair in Stroke Treatment: A Retrospective Survey in China
CONCLUSION: We showed that BGC shortened the procedural time and increased the rate of the successful FP. We recommend that BGC could be considered the preferred technique for endovascular intervention in stroke.PMID:36212711 | PMC:PMC9534624 | DOI:10.1155/2022/4278048
Source: Biomed Res - October 10, 2022 Category: Research Authors: Qiang Li Tengfei Zhou Yingkun He Min Guan Zhaoshuo Li Liheng Wu Changming Wen Haibo Wang Guang Feng Ziliang Wang Liangfu Zhu Tianxiao Li Source Type: research

The central-peripheral coupling effect of ocular acupuncture kinesitherapy in post-stroke dyskinesia: A functional neuroimaging and neurotic electrophysiology study protocol
This study is registered with an identifier (ChiCTR2200060483) at the Chinese Clinical Trial Registry in June 2022. http://www.chictr.org.cn/index.aspx.
Source: Frontiers in Neurology - September 1, 2022 Category: Neurology Source Type: research

Protocol for GUos renovisceral Artery reconstruction-1: a prospective, multicentre, single-arm clinical trial to evaluate the safety and efficacy of a multibRANched sTEnt graft systEm for thoracoabdominal aortic aneurysm (GUARANTEE study)
Introduction The multibranched off-the-shelf stent graft is a promising treatment option for thoracoabdominal aortic aneurysm (TAAA). A commercially available, multibranched, off-the-shelf endograft called the t-Branch stent graft has demonstrated favourable midterm outcomes. Another two investigational off-the-shelf endografts, the GORE EXCLUDER Thoracoabdominal Branch Endoprosthesis and E-nside multibranch stent graft system, are still being developed. However, these three endografts have an unsatisfactory anatomic feasibility rate in patients with TAAA. Based on the concept of Guo’s renovisceral artery reconstruct...
Source: BMJ Open - March 23, 2022 Category: General Medicine Authors: Ge, Y., Zhang, H., Rong, D., Liu, F., Jia, X., Xiong, J., Ma, X., Wang, L., Fan, T., Guo, W. Tags: Open access, Cardiovascular medicine Source Type: research

Corticocortical paired associative stimulation for treating motor dysfunction after stroke: study protocol for a randomised sham-controlled double-blind clinical trial
This study protocol aims to examine the corticocortical paired associative stimulation (ccPAS) for inducing synaptic plasticity to rescue the paralysed after stroke. Methods and analysis The current study is designed as a 14-week double-blind randomised sham-controlled clinical trial, composed of 2-week intervention and 12-week follow-up. For the study, 42 patients who had a stroke aged 40–70 will be recruited, who are randomly assigned either to the ccPAS intervention group, or to the control group at a 1:1 ratio, hence an equal number each. In the intervention group, ccPAS is practised in conjunction with the conv...
Source: BMJ Open - January 13, 2022 Category: General Medicine Authors: Duan, Y.-J., Hua, X.-Y., Zheng, M.-X., Wu, J.-J., Xing, X.-X., Li, Y.-L., Xu, J.-G. Tags: Open access, Rehabilitation medicine Source Type: research

Progress in Borneol Intervention for Ischemic Stroke: A Systematic Review
Conclusion: Borneol prevents neuronal injury after cerebral ischemia via multiple action mechanisms, and it can mobilize endogenous nutritional factors to hasten repair and regeneration of brain tissue. Because the neuroprotective effects of borneol are mediated by various therapeutic factors, deficiency caused by a single-target drug is avoided. Besides, borneol promotes other drugs to pass through the blood-brain barrier to exert synergistic therapeutic effects.
Source: Frontiers in Pharmacology - May 4, 2021 Category: Drugs & Pharmacology Source Type: research

Network pharmacology reveals the mechanism of activity of Tongqiao Huoxue Decoction Extract against middle cerebral artery occlusion-induced cerebral ischemia reperfusion injury
Some clinical therapies such as tissue repair by replacing injured with functional tissues have been reported, yet there is the great explore potential for traditional herbal-induced regeneration with good safety. Tongqiao Huoxue Decoction (TQHXD), a well-known classical traditional Chinese Medicinal formula, has been widely used for clinical treatment of stroke. However, biological activity and mechanisms of action of its constituents towards conferring protection against cerebral ischemia reperfusion (I/R) injury remain unclear. In this present study, we evaluated TQHXD quality using HPLC, then screened for its potential...
Source: Frontiers in Pharmacology - January 11, 2021 Category: Drugs & Pharmacology Source Type: research

Astragaloside IV promotes microglia/macrophages M2 polarization and enhances neurogenesis and angiogenesis through PPAR γ pathway after cerebral ischemia/reperfusion injury in rats.
Astragaloside IV promotes microglia/macrophages M2 polarization and enhances neurogenesis and angiogenesis through PPARγ pathway after cerebral ischemia/reperfusion injury in rats. Int Immunopharmacol. 2021 Jan 08;92:107335 Authors: Li L, Gan H, Jin H, Fang Y, Yang Y, Zhang J, Hu X, Chu L Abstract Microglia/macrophages play a dual role in brain injury and repair following cerebral ischemia/reperfusion. Promoting microglia/macrophage polarization from pro-inflammatory M1 to anti-inflammatory M2 phenotype has been considered as a potential treatment for ischemic stroke. Astragaloside IV (AS-IV) is a pr...
Source: International Immunopharmacology - January 8, 2021 Category: Allergy & Immunology Authors: Li L, Gan H, Jin H, Fang Y, Yang Y, Zhang J, Hu X, Chu L Tags: Int Immunopharmacol Source Type: research

First non-human primate study showing promise of gene therapy for stroke repair
(Guangdong-Hongkong-Macau Institute of CNS Regeneration,Jinan University) Stroke is a leading cause of death and severe long-term disability with limited treatment available. A research team led by Prof. Gong Chen at Jinan University, Guangzhou, China recently reported the first non-human primate study demonstrating successful in vivo neural regeneration from brain internal glial cells for stroke repair. This work was published on Frontiers in Cell and Developmental Biology on November 5th, 2020.
Source: EurekAlert! - Medicine and Health - November 13, 2020 Category: International Medicine & Public Health Source Type: news

Pages: 1  2  3