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What It Will Take to Avoid a Tripledemic This Winter
Over the coming months, more than 100,000 Americans will likely die, mostly unnecessarily, from respiratory infections. Yes, that is the reality we are now facing this fall and winter—and likely every fall and winter for the foreseeable future. Unless we act. Between flu, COVID-19, and RSV, we are likely looking at a very large number of Americans getting sick, ending up in the hospital, and dying. Most of these Americans will be our most vulnerable: older Americans, the youngest children, and those with chronic diseases. And that number of 100,000 may be an underestimate, given that many of these infections go undet...
Source: TIME: Health - September 22, 2023 Category: Consumer Health News Authors: Dr. Ashish K. Jha Tags: Uncategorized COVID-19 freelance Source Type: news

Many Americans Frustrated in Search for Low-Cost COVID Boosters
FRIDAY, Sept. 22, 2023 -- Americans seeking out the new COVID boosters are finding themselves held back by insurance entanglements and supply delays. Some insurers have balked at covering the vaccines, with people arriving at shot appointments only...
Source: Drugs.com - Daily MedNews - September 22, 2023 Category: General Medicine Source Type: news

Burden of COVID-19 during the omicron predominance in Brazil: a nationwide retrospective database study
CONCLUSIONS: This study quantified the burden of COVID-19 in Brazil, suggesting substantial healthcare resources required to manage the COVID-19 pandemic.PMID:37735817 | DOI:10.1080/13696998.2023.2262323
Source: Journal of Medical Economics - September 22, 2023 Category: Health Management Authors: Jingyan Yang Guilherme Cordeiro Mauricio Longato Shailja Vaghela Moe H Kyaw Carlos Fernando Mendoza Ana Dantas Thais Senna Pedro Holanda Julia Regazzini Spinardi Source Type: research

Regulatory circuits of mitophagy restrict distinct modes of cell death during memory CD8 < sup > + < /sup > T cell formation
Sci Immunol. 2023 Sep 29;8(87):eadf7579. doi: 10.1126/sciimmunol.adf7579. Epub 2023 Sep 22.ABSTRACTMitophagy, a central process guarding mitochondrial quality, is commonly impaired in human diseases such as Parkinson's disease, but its impact in adaptive immunity remains unclear. The differentiation and survival of memory CD8+ T cells rely on oxidative metabolism, a process that requires robust mitochondrial quality control. Here, we found that Parkinson's disease patients have a reduced frequency of CD8+ memory T cells compared with healthy donors and failed to form memory T cells upon vaccination against COVID-19, highli...
Source: Cancer Control - September 22, 2023 Category: Cancer & Oncology Authors: Fabien Franco Alessio Bevilacqua Ruey-Mei Wu Kung-Chi Kao Chun-Pu Lin Lor ène Rousseau Fu-Ti Peng Yu-Ming Chuang Jhan-Jie Peng Jaeoh Park Yingxi Xu Antonino Cassotta Yi-Ru Yu Daniel E Speiser Federica Sallusto Ping-Chih Ho Source Type: research

Gender Differences in Psychosocial Stress During the COVID-19 Pandemic: A Population-based Study in South Korea
CONCLUSIONS: The COVID-19 pandemic has exerted differential impacts on psychosocial stress among working-age individuals in South Korea, with women, particularly those in urban areas, experiencing a heightened risk. The findings highlight the importance of addressing gender-specific needs and implementing appropriate interventions to mitigate the psychosocial consequences of the pandemic.PMID:37735833 | DOI:10.3961/jpmph.23.170
Source: Journal of Preventive Medicine and Public Health - September 22, 2023 Category: International Medicine & Public Health Authors: Minku Kang Sarah Yu Seung-Ah Choe Daseul Moon Myung Ki Byung Chul Chun Source Type: research

News at a glance: Diphtheria vaccine shortage, prisoner release, and iNaturalist ’s growth
CONSERVATION Popular biodiversity app to expand The nonprofit that runs iNaturalist, a popular app and website for identifying species, has received a $10 million grant to expand. The funding from the Gordon and Betty Moore Foundation, announced last week, will allow iNaturalist—whose website is one of the largest generators of crowd-sourced species-occurrence data—to add users, technology, and observations to inform conservation. iNaturalist hopes to grow in nature-rich parts of the world, such as Asia and South America, which have fewer users uploading data. Since iNaturalist’s founding in 2008, the ...
Source: Science of Aging Knowledge Environment - September 21, 2023 Category: Geriatrics Source Type: research

News at a glance: Diphtheria treatment shortage, prisoner release, and iNaturalist ’s growth
CONSERVATION Popular biodiversity app to expand The nonprofit that runs iNaturalist, a popular app and website for identifying species, has received a $10 million grant to expand. The funding from the Gordon and Betty Moore Foundation, announced last week, will allow iNaturalist—whose website is one of the largest generators of crowd-sourced species-occurrence data—to add users, technology, and observations to inform conservation. iNaturalist hopes to grow in nature-rich parts of the world, such as Asia and South America, which have fewer users uploading data. Since iNaturalist’s founding in 2008, the ...
Source: ScienceNOW - September 21, 2023 Category: Science Source Type: news

Continued challenges in pediatric anesthesia during COVID-19 in 2022: An international survey from the pediatric anesthesia COVID-19 collaborative
CONCLUSION: Our study found that COVID-19 has continued to impact pediatric anesthesiology. There are major discrepancies between what anesthesiologists believe are important for job satisfaction and faculty retention compared to implemented initiatives. Data from this survey provide insight for institutions and departments for addressing these challenges.PMID:37732382 | DOI:10.1111/pan.14762
Source: Pain Physician - September 21, 2023 Category: Anesthesiology Authors: John Zhong Victoria Bradford Allison M Fernandez Andrew Infosino Codruta N Soneru Steven J Staffa Vidya T Raman Joseph Cravero David Zurakowski Petra M Meier Pediatric Anesthesia COVID-19 Collaborative Source Type: research

Can variants, reinfection, symptoms and test types affect COVID-19 diagnostic performance? A large-scale retrospective study of AG-RDTs during circulation of Delta and Omicron variants, Czechia, December 2021 to February 2022
ConclusionSensitivity for Omicron was lower in subgroups that may become more common if SARS-CoV-2 becomes an endemic virus.PMID:37733239 | DOI:10.2807/1560-7917.ES.2023.28.38.2200938
Source: Euro Surveill - September 21, 2023 Category: Infectious Diseases Authors: Tom áš Kliegr Ji ří Jarkovský Helena Ji řincová Jaroslav Kucha ř Tom áš Karel David Chud án Stanislav Voj íř Michal Zav řel Ond řej Šanca Ruth Tachezy Source Type: research

Continued challenges in pediatric anesthesia during COVID-19 in 2022: An international survey from the pediatric anesthesia COVID-19 collaborative
CONCLUSION: Our study found that COVID-19 has continued to impact pediatric anesthesiology. There are major discrepancies between what anesthesiologists believe are important for job satisfaction and faculty retention compared to implemented initiatives. Data from this survey provide insight for institutions and departments for addressing these challenges.PMID:37732382 | DOI:10.1111/pan.14762
Source: Paediatric Anaesthesia - September 21, 2023 Category: Anesthesiology Authors: John Zhong Victoria Bradford Allison M Fernandez Andrew Infosino Codruta N Soneru Steven J Staffa Vidya T Raman Joseph Cravero David Zurakowski Petra M Meier Pediatric Anesthesia COVID-19 Collaborative Source Type: research

Nanoparticles: a breakthrough in COVID-19 prevention, diagnosis and treatment
Arch Med Sci. 2021 Oct 15;19(5):1410-1420. doi: 10.5114/aoms/142103. eCollection 2023.ABSTRACTCoronavirus disease 2019 (COVID-19) is an infectious disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), declared a global pandemic by the World Health Organization (WHO). The three key principles in management of the COVID-19 pandemic are prevention, early detection and targeted treatment. Vaccine-based prevention together with early detection has already proven its efficacy in controlling the pandemic. Early detection of infected patients could substantially accelerate the implementation of treatment,...
Source: Archives of Medical Science - September 21, 2023 Category: Biomedical Science Authors: Aleksandra Skwarek Aleksandra G ąsecka Mi łosz J Jaguszewski Łukasz Szarpak Tomasz Dzieci ątkowski Krzysztof J Filipiak Source Type: research

Evaluating COVID-19 Response Within a Tribal Health Care Organization
Conclusion Our evaluation approach captured areas of importance to the tribal health organization and may be pertinent for other indigenous organizations and rural communities. It is especially important to consider tribal perspectives in response to COVID-19 because of the prior history with Western medicine and infectious diseases, and health care limitations experienced due to rurality.PMID:37731363 | DOI:10.7812/TPP/23.039
Source: The Permanente journal - September 21, 2023 Category: General Medicine Authors: Krista R Schaefer Brianna Triplett Olivia Lorenzo Michelle Aregood Donna Galbreath Denise A Dillard Ann Futterman Collier Source Type: research

Nervous system-related tropism of SARS-CoV-2 and autoimmunity in COVID-19 infection
This article is protected by copyright. All rights reserved.PMID:37733584 | DOI:10.1002/eji.202250230
Source: European Journal of Immunology - September 21, 2023 Category: Allergy & Immunology Authors: Robert Weissert Source Type: research