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Procedure: Pulmonary Function Testing

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Total 287 results found since Jan 2013.

Maternal Exposure of BALB/c Mice to Indoor NO2 and Allergic Asthma Syndrome in Offspring at Adulthood with Evaluation of DNA Methylation Associated Th2 Polarization
Conclusions: Maternal exposure to indoor environmental NO2 causes allergic asthma-related consequences in offspring absent any subsequent lung provocation and potentiates the symptoms of allergic asthma in adult offspring following postnatal allergic sensitization and challenge; this response is associated with the Th2-based immune response and DNA methylation of the IL4 gene. https://doi.org/10.1289/EHP685 Received: 19 June 2016 Revised: 07 June 2017 Accepted: 19 June 2017 Published: 13 September 2017 Address correspondence to N. Sang, College of Environment and Resource, Shanxi University, Taiyuan, Shanxi 030006, P...
Source: EHP Research - September 13, 2017 Category: Environmental Health Authors: Daniil Lyalko Tags: Research Source Type: research

Randomized Trial of Interventions to Improve Childhood Asthma in Homes with Wood-burning Stoves
Conclusions: Among children with asthma and chronic exposure to woodsmoke, an air-filter intervention that improved indoor air quality did not affect quality-of-life measures. Intent-to-treat analysis did show an improvement in the secondary measure of dPFV. Trial registration: ClincialTrials.gov NCT00807183. https://doi.org/10.1289/EHP849 Received: 21 July 2016 Revised: 13 June 2017 Accepted: 16 June 2017 Published: 13 September 2017 Address correspondence to C.W. Noonan, School of Public and Community Health Sciences, 32 Campus Dr., University of Montana, Missoula, MT 59812 USA. Telephone: (406) 243-4957; Fax: (406...
Source: EHP Research - September 13, 2017 Category: Environmental Health Authors: Daniil Lyalko Tags: Research Source Type: research

In Utero Exposure to Select Phenols and Phthalates and Respiratory Health in Five-Year-Old Boys: A Prospective Study
Conclusion: Ethyl-paraben, bisphenol A, 2,5-dichlorophenol, and DIDP tended to be associated with altered respiratory health, with ethyl-paraben and bisphenol A exhibiting some consistency across respiratory outcomes. The trends between bisphenol A pregnancy level and increased asthma and bronchiolitis/bronchitis rates in childhood were consistent with a previous cohort study. https://doi.org/10.1289/EHP1015 Received: 25 August 2016 Revised: 12 January 2017 Accepted: 26 January 2017 Published: 08 September 2017 Address correspondence to C. Vernet, Institute for Advanced Biosciences (IAB), Centre de Recherche INSERM�...
Source: EHP Research - September 8, 2017 Category: Environmental Health Authors: Daniil Lyalko Tags: Research Source Type: research

Allergic sensitization and objective measures of sleep in urban school-aged children with asthma.
CONCLUSION: More positive allergy test results were associated with poorer sleep outcomes measured objectively in this sample of urban children. Implications for environmental control interventions and asthma treatments in different racial and ethnic groups are discussed. PMID: 28890019 [PubMed - in process]
Source: Annals of Allergy, Asthma and Immunology - September 1, 2017 Category: Allergy & Immunology Authors: Esteban CA, Everhart RS, Kopel SJ, Klein RB, Koinis-Mitchell D Tags: Ann Allergy Asthma Immunol Source Type: research

Elemental Sulfur Use and Associations with Pediatric Lung Function and Respiratory Symptoms in an Agricultural Community (California, USA)
Conclusions: This study suggests that elemental sulfur use, allowed in both organic and conventional farming, in close proximity to residential areas, may adversely affect children’s respiratory health. https://doi.org/10.1289/EHP528 Received: 19 May 2016 Revised: 05 May 2017 Accepted: 09 May 2017 Published: 14 August 2017 Address correspondence to R. Raanan, Center for Environmental Research and Children’s Health (CERCH), University of California, Berkeley, School of Public Health, 1995 University Ave., Suite 265, Berkeley, CA 94704 USA. Telephone: (510) 642-9431. Email: rachelraananrr@gmail.com Supplemental Ma...
Source: EHP Research - August 14, 2017 Category: Environmental Health Authors: Daniil Lyalko Tags: Research Source Type: research

Characteristics of severe asthma with fungal sensitization.
CONCLUSION: Severe asthma with fungal sensitization is characterized by early onset of disease and high serum levels of interleukin-33. Multiple fungal sensitizations are associated with poor asthma control. TRIAL REGISTRATION: UMIN Clinical Trials Registry (UMIN-CTR; www.umin.ac.jp/ctr/index-j.htm): UMIN 000002980. PMID: 28801088 [PubMed - as supplied by publisher]
Source: Annals of Allergy, Asthma and Immunology - August 8, 2017 Category: Allergy & Immunology Authors: Masaki K, Fukunaga K, Matsusaka M, Kabata H, Tanosaki T, Mochimaru T, Kamatani T, Ohtsuka K, Baba R, Ueda S, Suzuki Y, Sakamaki F, Oyamada Y, Inoue T, Oguma T, Sayama K, Koh H, Nakamura M, Umeda A, Kamei K, Izuhara K, Asano K, Betsuyaku T Tags: Ann Allergy Asthma Immunol Source Type: research

Association of neck circumference and pulmonary function in children.
CONCLUSION: We identified NC as a novel anthropometric index that is strongly correlated with respiratory functions in children. Therefore, close monitoring of respiratory symptoms, particularly in children with obesity and a large NC, could help with early and prompt determination of respiratory complications of obesity. PMID: 28527867 [PubMed - as supplied by publisher]
Source: Annals of Allergy, Asthma and Immunology - May 17, 2017 Category: Allergy & Immunology Authors: Akın O, Arslan M, Haymana C, Karabulut E, Hacihamdioglu B, Yavuz ST Tags: Ann Allergy Asthma Immunol Source Type: research

Evaluation of pulmonary complications in patients with primary immunodeficiency disorders.
Conclusion. Pulmonary complications should be considered in cases with PIDs especially in CVID cases. PMID: 28497675 [PubMed - in process]
Source: European Annals of Allergy and Clinical Immunology - May 13, 2017 Category: Allergy & Immunology Tags: Eur Ann Allergy Clin Immunol Source Type: research

Clinical, functional and inflammatory characteristics in patients with paucigranulocytic stable asthma: Comparison with different sputum phenotypes
ConclusionPaucigranulocytic asthma most likely represents a “benign” asthma phenotype, related to a good response to treatment, rather than a “true” phenotype of asthma. However, paucigranulocytic patients that remain not well controlled despite optimal treatment represent an asthmatic population that requires further study for potential novel targeted interventions.
Source: Allergy - May 11, 2017 Category: Allergy & Immunology Authors: P. Ntontsi, S. Loukides, P. Bakakos, K. Kostikas, G. Papatheodorou, E. Papathanassiou, G. Hillas, N. Koulouris, S. Papiris, A. I. Papaioannou Tags: ORIGINAL ARTICLE Source Type: research

Airway basophils are increased and activated in eosinophilic asthma
ConclusionThe number of activated basophils was increased in the sputum of patients with eosinophilic asthma and correlated with airway and blood eosinophils. Our observations suggest that sputum basophils may serve as a biomarker to monitor new therapeutic approaches for the treatment of eosinophilic asthma.This article is protected by copyright. All rights reserved.
Source: Allergy - May 5, 2017 Category: Allergy & Immunology Authors: Yoshihiro Suzuki, Keiko Wakahara, Tomoko Nishio, Satoru Ito, Yoshinori Hasegawa Tags: Original Article: Experimental Allergy and Immunology Source Type: research

F508del genotype in endoscopic sinus surgery: do differences in outcomes exist between genotypic subgroups?
ConclusionPrior studies investigating the impact of ESS on pulmonary function in CF patients have shown conflicting results. To our knowledge, those earlier udies did not separate and compare different genotypes, which may have introduced heterogeneity in their patient populations. Our study suggests that grouping CF patients more strictly according to genotype or disease severity when investigating outcomes may reveal differences among various subgroups.
Source: International Forum of Allergy and Rhinology - February 8, 2017 Category: Allergy & Immunology Authors: Ashleigh A. Halderman, Natalie West, James Benke, Christopher R. Roxbury, Sandra Y. Lin Tags: ORIGINAL ARTICLE Source Type: research

Effect of Nigella sativa supplementation on lung function and inflammatory mediators in partly controlled asthma: a randomized controlled trial
CONCLUSION:N sativa supplementation with inhaled maintenance therapy improves some measures of pulmonary function and inflammation in partly controlled asthma. LIMITATIONS:No bronchoalveolar lavage or sputum samples taken for measurement of asthma markers. ISRCTN registry: ISRCTN48853858 DOI 10.1186/ISRCTN48853858  
Source: Annals of Saudi Medicine - February 2, 2017 Category: Journals (General) Tags: ISSUE 1 Source Type: research

Effect of Nigella sativa supplementation on lung function and inflammatory mediatorsin partly controlled asthma: a randomized controlled trial
CONCLUSION:N sativa supplementation with inhaled maintenance therapy improves some measures of pulmonary function and inflammation in partly controlled asthma. LIMITATIONS:No bronchoalveolar lavage or sputum samples taken for measurement of asthma markers. ISRCTN registry: ISRCTN48853858 DOI 10.1186/ISRCTN48853858  
Source: Annals of Saudi Medicine - February 2, 2017 Category: Journals (General) Tags: ISSUE 1 Source Type: research

Determinants and outcomes of upfront surgery versus medical therapy for chronic rhinosinusitis in cystic fibrosis
ConclusionsSurgery effectively reduces CRS‐related symptoms in CF patients but may not improve pulmonary function. In patients who first pursue medical therapy, symptomatic decline may prompt eventual conversion to surgery. Patients who delay surgery may achieve similar outcomes as those who pursue surgery upfront.
Source: International Forum of Allergy and Rhinology - January 31, 2017 Category: Allergy & Immunology Authors: Noel Ayoub, Andrew Thamboo, Al ‐Rahim Habib, Jayakar V. Nayak, Peter H. Hwang Tags: ORIGINAL ARTICLE Source Type: research

Athletes Do Not Condition Inspired Air More Effectively than Nonathletes during Hyperpnea
Conclusion: This study shows no evidence of improved capacity to condition inspired air in endurance athletes, which could have suggested an increased bronchial blood flow or another adaptive mechanism. The absence of an adaptive mechanism could therefore contribute to airway damage observed in athletes in allowing colder but mainly dryer air to penetrate deeper in the lung.
Source: Medicine and Science in Sports and Exercise - December 16, 2016 Category: Sports Medicine Tags: Applied Sciences Source Type: research