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Total 214 results found since Jan 2013.

Is ventilation heterogeneity related to asthma control?
In asthma patients, magnetic resonance imaging (MRI) and the lung clearance index (LCI) have revealed persistent ventilation heterogeneity, although its relationship to asthma control is not well understood. Therefore, our goal was to explore the relationship of MRI ventilation defects and the LCI with asthma control and quality of life in patients with severe, poorly controlled asthma. 18 patients with severe, poorly controlled asthma (mean±sd 46±12 years, six males/12 females) provided written informed consent to an ethics board approved protocol, and underwent spirometry, LCI and 3He MRI during a sing...
Source: European Respiratory Journal - July 30, 2016 Category: Respiratory Medicine Authors: Svenningsen, S., Nair, P., Guo, F., McCormack, D. G., Parraga, G. Tags: Asthma and allergy Original Articles: Asthma Source Type: research

Premedication of pregnant patients with history of iodinated contrast allergy
Abstract Pregnant patients can receive allergy premedication prior to a contrast-enhanced computed tomography exam if the exam is indicated. The risks and benefits of allergy premedication for pregnant patients will be discussed, as well as imaging strategies for the pregnant patient with a contrast allergy. Alternative imaging including ultrasound, noncontrast magnetic resonance imaging, or noncontrast computed tomography can be diagnostic depending on the clinical scenario and is usually preferred, allowing physicians to avoid giving allergy premedication in pregnancy, a 13  h delay, and risking a breakthrough reaction.
Source: Abdominal Imaging - July 21, 2016 Category: Radiology Source Type: research

Myelin Oligodendrocyte Glycoprotein Antibody Persistency in a Steroid-Dependent ADEM Case
Myelin oligodendrocyte glycoprotein (MOG) is a candidate target antigen in demyelinating central nervous system diseases, including acute disseminated encephalomyelitis (ADEM), neuromyelitis optica, and multiple sclerosis. It may give prognostic information regarding monophasic or recurrent course of the disease. MOG antibodies have been shown to be positive in high titers during the first episode of ADEM with rapidly decreasing to undetectable limits after recovery. However, persistent MOG antibodies are considered as a predicting factor for multiple sclerosis, optic neuritis relapses, and incomplete recovery of ADEM. Her...
Source: PEDIATRICS - May 1, 2016 Category: Pediatrics Authors: Polat, I., Yis, U., Karaoglu, P., Ayanoglu, M., Öztürk, T., Güleryüz, H., Kurul, S. H. Tags: Neurology, Neurologic Disorders, Allergy/Immunology, Immunologic Disorders Case Report Source Type: research

Magnetic resonance imaging reveals the complementary effects of decongestant and Breathe Right Nasal Strips on internal nasal anatomy
ConclusionsThe BRNS alone significantly increases nasal patency and alleviates perceived nasal congestion, and additional relief of symptoms can be obtained with simultaneous use of a decongestant. Level of Evidence1b. Laryngoscope, 2016
Source: The Laryngoscope - February 10, 2016 Category: ENT & OMF Authors: Courtney A. Bishop, Steven M. Johnson, Matthew B. Wall, Robert L. Janiczek, Gilbert Shanga, Richard G. Wise, Rexford D. Newbould, Philip S. Murphy Tags: Allergy/Rhinology Source Type: research

Cardiovascular Magnetic Resonance Imaging clarifies cardiac pathophysiology in early, asymptomatic diffuse systemic sclerosis
Source: Inflammation and Allergy Drug Targets - January 12, 2016 Category: Allergy & Immunology Authors: I. Mavrogeni, SophieBratis, KonstantinosKarabela, GeorgiaSpiliotis, Georgevan Wijk, KeesHautemann, DavidH.C. Reiber, JohanKoutsogeorgopoulou, LoukiaMarkousis-Mavrogenis, GeorgeKolovou, GenovefaStavropoulos, Efthymios Tags: Articles Source Type: research

Spontaneous complete regression of hypothalamic pilocytic astrocytoma after partial resection in a child, complicated with Stevens-Johnson syndrome: a case report and literature review
We report a well-documented case of spontaneous regression hypothalamic PA after partial resection that complicated with SJS. Immune system reaction in SJS may have a role in tumor behavior and spontaneous regression. Multiple studies confirmed spontaneous regression in PA after partial/subtotal resection. This phenomenon occurs due to humoral and cell-mediated host immune responses to the implanted tumor. The immune system reaction in SJS may have a role in tumor behavior and spontaneous regression.
Source: Neurosurgical Review - December 14, 2015 Category: Neurosurgery Source Type: research

Primary pulmonary haemosiderosis. Usefulness of MRI with DWI
To evaluate the usefulness of MRI with DWI for distinguishing lung findings in investigation of primary pulmonary haemosiderosis.We enrolled 31 patients with clinically confirmed primary pulmonary haemosiderosis who underwent magnetic resonance imaging (MRI) including diffusion-weighted imaging (DWI). Male patients were 20 (65.52%), female 11 (34.48%). Patients were from 17 to 83 years old. Two thoracic radiologists reviewed MR images including unenhanced T1- and T2-weighted images, gadolinium-enhanced images and DWI images.MRI findings present three types of haemosiderosis. First was pulmonary haemosiderosis associated wi...
Source: European Respiratory Journal - October 30, 2015 Category: Respiratory Medicine Authors: Ivkovic, S., Ivkovic, A., Milosavljevic, T., Ivkovic, D. Tags: 1.3 Imaging Source Type: research

Clinical correlates of lung ventilation defects in asthmatic children
Lung ventilation defects identified by using hyperpolarized 3-helium gas (3He) lung magnetic resonance imaging (MRI) are prevalent in asthmatic patients, but the clinical importance of ventilation defects is poorly understood.
Source: Journal of Allergy and Clinical Immunology - October 29, 2015 Category: Allergy & Immunology Authors: Talissa A. Altes, John P. Mugler, Kai Ruppert, Nicholas J. Tustison, Joanne Gersbach, Sylvia Szentpetery, Craig H. Meyer, Eduard E. de Lange, W. Gerald Teague Source Type: research

Analysis of the topic study using 2010 mcdonald criteria
Conclusions Teriflunomide demonstrates a consistent treatment effect in patients with MS diagnosed according to differing diagnostic criteria. (Study supported by Genzyme, a Sanofi company).
Source: Journal of Neurology, Neurosurgery and Psychiatry - October 14, 2015 Category: Neurosurgery Authors: Rog, D., Wolinsky, J., Truffinet, P., Thangavelu, K., Miller, A. Tags: Immunology (including allergy), Multiple sclerosis, Radiology, Radiology (diagnostics) Thur 21, Parallel session 5: Therapeutics Source Type: research

Cerebral vasculitis histopathology in relapsing polychondritis
We describe here the histopathological features of RPC with CNS involvement in a 65-year-old gentleman that presented with rapidly progressive cognitive decline, fevers and ataxia over six weeks. He had bilateral auricular inflammation with cartilage destruction, but relative lobe sparing, ocular inflammation, and a symmetrical small-joint polyarthropathy. The cerebrospinal fluid showed lymphocytic pleocytosis. Diffuse sub-cortical white matter abnormalities were seen on magnetic resonance imaging. A clinical diagnosis of RPC was made on the basis of McAdam criteria. Routinely stained histological brain sections showed sca...
Source: Journal of Neurology, Neurosurgery and Psychiatry - October 14, 2015 Category: Neurosurgery Authors: Mbizvo, G., Ellis, R., Michael, B., Rathi, N., Doran, M., Crooks, D. Tags: Immunology (including allergy), Memory disorders (psychiatry), Radiology, Connective tissue disease, Musculoskeletal syndromes, Vascularitis, Radiology (diagnostics) Thur 21, Parallel session 5: Therapeutics Source Type: research

Cardiovascular Magnetic Resonance Imaging clarifies cardiac pathophysiology in early, asymptomatic diffuse systemic sclerosis.
CONCLUSIONS: CMR may reveal severe cardiac involvement in early, asymptomatic diffuse SSc with normal routine cardiac evaluation, presenting either as myocardial inflammation or as severe reduction of MPRI and diffuse fibrosis with further deterioration in the long term follow up. PMID: 26374223 [PubMed - as supplied by publisher]
Source: Inflammation and Allergy Drug Targets - September 16, 2015 Category: Allergy & Immunology Authors: Mavrogeni S, Bratis K, Karabela G, Spiliotis G, van Wijk K, Hautemann D, Reiber JH, Koutsogeorgopoulou L, Markousis-Mavrogenis G, Kolovou G, Stavropoulos E Tags: Inflamm Allergy Drug Targets Source Type: research

Endoscopic surgery of the orbital apex: Outcomes and emerging techniques
ConclusionsThe endoscopic approach to the orbit apex offers significant advantages over traditional external approaches, and should be the preferred approach for all medial and inferior lesions. A two‐surgeon multihanded technique can help facilitate difficult cases. Level of Evidence4. Laryngoscope, 2015
Source: The Laryngoscope - August 22, 2015 Category: ENT & OMF Authors: Janalee Stokken, Divya Gumber, Jastin Antisdel, Raj Sindwani Tags: Allergy/Rhinology Source Type: research

Development of an ASAS-endorsed recommendation for the early referral of patients with a suspicion of axial spondyloarthritis
The aim of this work was to develop a consensual recommendation under the auspices of the Assessment of SpondyloArthritis international Society (ASAS) for early referral of patients with a suspicion of axial spondyloarthritis by non-rheumatologists. The development of a referral recommendation consisted of four phases: (1) systematic literature review, (2) the first Delphi round aiming at identification of unmet needs and development of a candidate list of referral parameters, (3) the second Delphi round aiming at identification of the most useful combination of referral parameters and (4) final discussion and formal endor...
Source: Annals of the Rheumatic Diseases - July 9, 2015 Category: Rheumatology Authors: Poddubnyy, D., van Tubergen, A., Landewe, R., Sieper, J., van der Heijde, D., on behalf of the Assessment of SpondyloArthritis international Society (ASAS) Tags: Inflammatory bowel disease, Immunology (including allergy), Pain (neurology), Ophthalmology, Radiology, Biological agents, Degenerative joint disease, Drugs: musculoskeletal and joint diseases, Musculoskeletal syndromes, Clinical diagnostic tests, Radiolo Source Type: research

Evolution of nonspecific duodenal lymphocytosis over 2 years of follow-up.
CONCLUSION: DL may have a multifactorial origin but the IELs infiltrate and HLA are strong predictive factors for CD development and a clinical diagnosis of GS. PMID: 26140001 [PubMed - in process]
Source: World Journal of Gastroenterology : WJG - June 28, 2015 Category: Gastroenterology Authors: Losurdo G, Piscitelli D, Giangaspero A, Principi M, Buffelli F, Giorgio F, Montenegro L, Sorrentino C, Amoruso A, Ierardi E, Di Leo A Tags: World J Gastroenterol Source Type: research

Management of the orbit during endoscopic sinonasal tumor surgery
ConclusionThis represents the largest series to date on endoscopic management of the orbit in benign and malignant sinonasal tumors. A majority of these cases can be managed by a purely endoscopic approach with low complication and recurrence rates, although a subset still require adjunct open approaches for successful tumor extirpation.
Source: International Forum of Allergy and Rhinology - June 11, 2015 Category: Allergy & Immunology Authors: Brandon Christianson, Carlos Perez, Brian Harrow, Pete S. Batra Tags: ORIGINAL ARTICLE Source Type: research