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Total 517 results found since Jan 2013.

Clinical characteristics of central compartment atopic disease in Southern China
ConclusionCCAD in Southern China may associate with asthma and significant eosinophilia, with a lower incidence of systemic allergy based on skin and serum testing.
Source: International Forum of Allergy and Rhinology - September 21, 2022 Category: Allergy & Immunology Authors: Zhiying Nie, Zhaofeng Xu, Yunping Fan, Yuanyuan Guo, Chuxin Chen, Wendong Liu, Yueqi Li, Yinyan Lai, Jianbo Shi, Fenghong Chen Tags: ORIGINAL ARTICLE Source Type: research

Eosinophilic esophagitis patients with multiple atopic conditions: Clinical characteristics and treatment response to topical steroids
CONCLUSION: There were differences in initial presentation of EoE between those with and without multiple atopic conditions, but there were no major differences in histologic treatment response to corticosteroids by atopic status.PMID:37100277 | DOI:10.1016/j.anai.2023.04.026
Source: Annals of Allergy, Asthma and Immunology - April 26, 2023 Category: Allergy & Immunology Authors: Walker D Redd Adolfo A Ocampo Zeyun Xue Nicole C Chang Kisan P Thakkar Sumana B Reddy Sydney B Greenberg Christopher J Lee Corey J Ketchem Swathi Eluri Craig C Reed Evan S Dellon Source Type: research

Body Mass Index in relation to symptom presentation upon diagnosis of Eosinophilic Esophagitis in Children
CONCLUSION: Nearly one-third of children were obese or overweight status upon diagnosis with EoE. Children with BMI in the overweight or obese range were more likely to be older at diagnosis and to have a chief complaint of abdominal pain on presentation.PMID:37311509 | DOI:10.1016/j.anai.2023.06.004
Source: Annals of Allergy, Asthma and Immunology - June 13, 2023 Category: Allergy & Immunology Authors: Rebecca Koenigsberg Sandeep Gupta James E Slaven Tara Sarin Girish Vitalpur Source Type: research

Empiric 6-food elimination diet induced and maintained prolonged remission in patients with adult eosinophilic esophagitis: A prospective study on the food cause of the disease
Background: Although empiric exclusion from the diet of the 6 food groups most likely to trigger allergies achieves eosinophilic esophagitis (EoE) remission in children, data on its prolonged efficacy and effects on adults are lacking.Objective: We sought to evaluate the efficacy of a 6-food elimination diet in inducing and maintaining prolonged remission in patients with adult EoE.Methods: Sixty-seven consecutive patients with adult EoE were prospectively recruited and treated exclusively with a diet avoiding cereals, milk, eggs, fish/seafood, legumes/peanuts, and soy for 6 weeks. Subsequent challenge was undertaken by se...
Source: Journal of Allergy and Clinical Immunology - February 4, 2013 Category: Allergy & Immunology Authors: Alfredo J. Lucendo, Ángel Arias, Jesús González-Cervera, José Luis Yagüe-Compadre, Danila Guagnozzi, Teresa Angueira, Susana Jiménez-Contreras, Sonia González-Castillo, Benito Rodríguez-Domíngez, Livia C. De Rezende, José M. Tenias Tags: Food, drug, insect sting allergy, and anaphylaxis Source Type: research

Eosinophilic oesophagitis in children: responders and non-responders to swallowed fluticasone
Conclusions Clinical characteristics of children with EO at baseline were similar in responders and non-responders, but a more severe inflammation in oesophageal mucosa was associated with a higher response rate to fluticasone treatment.
Source: Journal of Clinical Pathology - April 21, 2013 Category: Pathology Authors: Boldorini, R., Mercalli, F., Oderda, G. Tags: Immunology (including allergy), Inflammation Original article Source Type: research

Taste test
When describing how most kids react to a plate of their least favorite foods, the term melodramatic would be an understatement. “If I have one more bite of broccoli, I’m going to be sick!” “Yuck! Spinach again? It makes me gag.” But for a small portion of kids, these terms aren’t exaggerations; they’re medically accurate statements. Cameron Ledin is one of those children. The 8-year-old was recently diagnosed with eosinophilic esophagitis (EoE), a severe allergic inflammation of the esophagus that causes his body to have terrible reactions to a wide range of foods. When a person wi...
Source: Thrive, Children's Hospital Boston - May 21, 2013 Category: Pediatrics Authors: Tripp Underwood Tags: All posts Asthma & allergies Diseases & conditions Food allergies (EoE) clinical trial food allergy Eitan Runinstein eosinophilic esophagitis Eosinophilic Gastrointestinal Disease (EGID) Program John Lee Source Type: news

The Editors' Choice
Cow's milk is one of the most common foods causing eosinophilic esophagitis (EoE). Elimination of cow's milk from the diet is an effective nonpharmacologic treatment of cow's milk–mediated EoE (CMME). However, adherence to a milk-free diet is difficult because milk proteins are also present in baked foods, such as muffins, cakes, and breads. Studies show that a majority of children with IgE-mediated allergy to cow's milk can tolerate baked milk products, but it is not known whether patients with CMME can tolerate baked milk products. As reported in this issue, John Leung et al (p 1215) looked at the clinical outcome of...
Source: Journal of Allergy and Clinical Immunology - October 30, 2013 Category: Allergy & Immunology Authors: Donald Y.M. Leung, Stanley J. Szefler, Associate Editors of the JACI Tags: The Editors' choice Source Type: research

Propofol administration is safe in adult eosinophilic esophagitis patients sensitized to egg, soy, or peanut
ConclusionsPropofol was safely administered for procedural sedation in a large series of adult EoE patients multisensitized to egg, soy, peanut, showing one‐third clinical allergy to these foods.
Source: Allergy - January 21, 2014 Category: Allergy & Immunology Authors: J. Molina‐Infante, A. Arias, D. Vara‐Brenes, R. Prados‐Manzano, J. Gonzalez‐Cervera, M. Alvarado‐Arenas, A. J. Lucendo Tags: Original Article Source Type: research

The contribution of erectile elements to nasal patency: an examination with nasal sound analysis
ConclusionOR is an efficient and reliable method to evaluate the role of the erectile components in nasal patency in the absence of allergy or septal deviation. It is practical and may be used in routine clinical practice.
Source: International Forum of Allergy and Rhinology - October 20, 2014 Category: Allergy & Immunology Authors: Rauf Tahamiler, Yalçin Alimoglu, Salih Canakcioglu Tags: ORIGINAL ARTICLE Source Type: research

Nasal lavage levels of granulocyte‐macrophage colony‐stimulating factor and chronic nasal hypereosinophilia
ConclusionOur data confirm that GM‐CSF is more frequently detectable in nasal lavages of patients affected by chronic sinonasal eosinophilic inflammation than in controls. Statistical analyses revealed a significant weakly‐moderate correlation between GM‐CSF levels in nasal lavage of all patients and percentage of eosinophil infiltration of nasal mucosa.
Source: International Forum of Allergy and Rhinology - March 26, 2015 Category: Allergy & Immunology Authors: Eugenio Corso, Silvia Baroni, Daniela Lucidi, Mariapina Battista, Matteo Romanello, Chiara Autilio, Renato Morelli, Walter Di Nardo, Giulio Cesare Passali, Bruno Sergi, Francesco Bussu, Anna Rita Fetoni, Cecilia Zuppi, Gaetano Paludetti Tags: ORIGINAL ARTICLE Source Type: research

Asthma Control and Airway Inflammation in Patients with Eosinophilic Granulomatosis with Polyangiitis
Conclusions Systemic treatment controls systemic involvement in EGPA, but not asthma and nasal diseases, which negatively affects patients' quality of life.
Source: The Journal of Allergy and Clinical Immunology: In Practice - March 5, 2016 Category: Allergy & Immunology Source Type: research

The effects of concomitant GERD, dyspepsia, and rhinosinusitis on asthma symptoms and FeNO in asthmatic patients taking controller medications
Conclusion: Daytime phlegm and losing the sense of smell suggest that eosinophilic airway inflammation persists, despite anti-inflammatory therapy, in patients with asthma. Although rhinitis and GERD made the subjective symptoms of asthma worse, they did not seem to enhance eosinophilic airway inflammation. Keywords: asthma symptoms, FeNO, rhinosinusitis, GERD, dyspepsia 
Source: Journal of Asthma and Allergy - September 5, 2014 Category: Allergy & Immunology Tags: Journal of Asthma and Allergy Source Type: research

Other Phenotypes and Treatment of Chronic Rhinosinusitis
This article comments on some factors that are believed to influence the expression of CRS. These factors include anatomic abnormalities, immotile cilia, age, allergic sensitization, immune deficiency, dental infections, gastrointestinal reflux, smoking, biofilm, and the microbiome. Other factors are discussed in other sections. The article concludes with an overview of treatment. In brief, nasal steroids and large volume nasal irrigations are the first line of treatment for this inflammatory disease. Antibiotics are used when infections are thought to contribute. Oral steroids are frequently used in severe disease. Endosc...
Source: The Journal of Allergy and Clinical Immunology: In Practice - July 6, 2016 Category: Allergy & Immunology Source Type: research

Phenotypes and Emerging Endotypes of Chronic Rhinosinusitis
Publication date: July–August 2016 Source:The Journal of Allergy and Clinical Immunology: In Practice, Volume 4, Issue 4 Author(s): Claus Bachert, Cezmi A. Akdis Chronic rhinosinusitis can be differentiated into several phenotypes based on clinical criteria; however, these phenotypes do not teach us much about the underlying inflammatory mechanisms. Thus, the use of nasal endoscopy and CT scanning, and eventually taking a swab or a biopsy, may not be sufficient to fully appreciate the individual patient's pathology. Endotyping of chronic rhinosinusitis on the basis of pathomechanisms, functionally and pathologically ...
Source: The Journal of Allergy and Clinical Immunology: In Practice - July 6, 2016 Category: Allergy & Immunology Source Type: research