Filtered By:
Therapy: Steroid Therapy

This page shows you your search results in order of relevance. This is page number 4.

Order by Relevance | Date

Total 83 results found since Jan 2013.

Translating New Developments in Eosinophilic Esophagitis Pathogenesis into Clinical Practice
Opinion statement New developments in eosinophilic esophagitis (EoE) pathogenesis are shaping our current therapeutic and management strategies. EoE is a chronic allergic inflammatory disease with progression to fibrostenotic disease. The disease warrants early diagnosis and long-term maintenance therapy. The diagnosis of EoE should be based on the concept of an allergy-mediated disease with esophageal dysfunction and esophageal eosinophilia. Recent findings suggest that proton pump inhibitor (PPI)-responsive esophageal eosinophilia (PPI-REE) is likely a continuum of EoE or a similar T-helper 2 (Th2)-mediated alle...
Source: Current Treatment Options in Gastroenterology - January 20, 2015 Category: Gastroenterology Source Type: research

Myelin Oligodendrocyte Glycoprotein Antibody Persistency in a Steroid-Dependent ADEM Case
Myelin oligodendrocyte glycoprotein (MOG) is a candidate target antigen in demyelinating central nervous system diseases, including acute disseminated encephalomyelitis (ADEM), neuromyelitis optica, and multiple sclerosis. It may give prognostic information regarding monophasic or recurrent course of the disease. MOG antibodies have been shown to be positive in high titers during the first episode of ADEM with rapidly decreasing to undetectable limits after recovery. However, persistent MOG antibodies are considered as a predicting factor for multiple sclerosis, optic neuritis relapses, and incomplete recovery of ADEM. Her...
Source: PEDIATRICS - May 1, 2016 Category: Pediatrics Authors: Polat, I., Yis, U., Karaoglu, P., Ayanoglu, M., Öztürk, T., Güleryüz, H., Kurul, S. H. Tags: Neurology, Neurologic Disorders, Allergy/Immunology, Immunologic Disorders Case Report Source Type: research

Steroid Therapy and Conduction Disturbances after Transcatheter Aortic Valve Implantation
ConclusionAlthough safe, steroid treatment prior to TAVI failed to reduce the incidence of new conduction defects and the need for pacemaker implantation.This article is protected by copyright. All rights reserved.
Source: Cardiovascular Therapeutics - May 31, 2016 Category: Cardiology Authors: Ofer Havakuk, Maayan Konigstein, Eyal Ben Assa, Yaron Arbel, Yigal Abramowitz, Amir Halkin, Samuel Bazan, Haim Shmilovich, Gad Keren, Ariel Finkelstein, Shmuel Banai Tags: Original Research Article Source Type: research

The Association Between 25 Hydroxyvitamin D and Airway Obstruction in Asthma.
Abstract Since Vitamin D has anti-inflammatory effects we wondered whether the association between low serum 25OHD and airway obstruction in moderate persistent asthma might be explained by inflammatory pathways that worsen asthma. All subjects examined were Irish Caucasians with moderate persistent asthma and none took systemic steroid therapy. In addition to computerized spirometry, we measured BMI, serum 25-hydroxyvitamin D (25OHD), total IgE, Eosinophil Cationic Protein (ECP), and high sensitive C- reactive protein (hs-CRP). One hundred (47 male) subjects completed the testing. Within single level of asthma se...
Source: Ir Med J - October 1, 2016 Category: Journals (General) Authors: Hutchinson K, Kerley C, Cormican L, Rochev Y, Faul J Tags: Ir Med J Source Type: research

Investigating antioxidant therapy for steroid-resistant asthma
Conclusions: SRAAD is associated with increased oxidative stress that are resistant to steroids. Our findings suggest that antioxidant therapy may be appropriate for SR asthma especially when combined with steroid therapy.
Source: European Respiratory Journal - November 7, 2016 Category: Respiratory Medicine Authors: Pinkerton, J., Kim, R., Essilfie, A.-T., Rae, B., Mayall, J., Ali, M. K., Starkey, M., Wood, L., Biswal, S., Horvat, J., Hansbro, P. Tags: 5.3 Allergy and Immunology Source Type: research

Eosinophilia and predominant Th2 immune responses are rarely evident in disseminated tuberculosis
Conclusion: We could find no evidence of frequent asthma or heightened Th2 immunity (high blood eosinophils) in disseminated TB. It is possible that measuring blood counts at time of presentation is too late to detect any eosinophilia present earlier when they first acquired TB and failed to mount an early effective immune response. The eosinopaenia in these patients may reflect Th1 immune responses suppressing Th2 responses, and there is limited evidence that BCG vaccination may be able to suppress asthmatic inflammation.
Source: European Respiratory Journal - November 7, 2016 Category: Respiratory Medicine Authors: Pfeffer, P., Burman, M., Milton, V., Naidu, V., Vaghela, D., Kunst, H. Tags: 10.2 Tuberculosis Source Type: research

Codeine for treatment of cough variant asthma
Cough variant asthma (CVA) is a special phenotype of asthma. Despite standart regimens, the treatment and control of CVA is difficult and can cause complications. Some patients have persistant symptoms despite inhaler bronchodilator and steroid therapy. Central cough supressants, such as codeine and dextromethorphan are recommended for symptomatic relief of cough in patients with chronic bronchitis but there is limited scientific data about their usage in asthma patients.We evaluate 16 CVA-phenotype asthmatic patients who had to use codeine, who were unresponsive to conventional asthma medications. We analysed demographic ...
Source: European Respiratory Journal - November 7, 2016 Category: Respiratory Medicine Authors: Erdogan, T., Ozturk Aktas, O., Celebioglu, E., Karakaya, G., Kalyoncu, A. F. Tags: 1.11 Clinical Problems - Asthma Source Type: research

Can liquorice make steroids more palatable in multiple sclerosis?
Conclusion We have shown that administration of liquorice prior to steroid therapy reduces the severity of the metallic taste by half and was beneficial in over 90% of patients.
Source: Journal of Neurology, Neurosurgery and Psychiatry - November 14, 2016 Category: Neurosurgery Authors: Low, S., Chataway, J. Tags: Immunology (including allergy), Multiple sclerosis ABN Annual Meeting, 17-19 May 2016, The Brighton Centre, Brighton Source Type: research

Intracerebral haemorrhage in normotensive patient with probable neurosaroidosis
Conclusion Vasculopathy in neurosarcoidosis results from granulomatous destruction of vessel walls, perivascular inflammation and/or steroid-induced collagen fragility. This case highlights an under-recognised and serious complication that may occur as a result. Aggressive disease suppression via immunomodulatory treatment may help minimise the risk of haemorrhagic events.
Source: Journal of Neurology, Neurosurgery and Psychiatry - November 14, 2016 Category: Neurosurgery Authors: Mirza, F., Das, J., Chauhan, V., Cooper, P., Pace, A. Tags: Immunology (including allergy), Neuroimaging, Radiology, Vascularitis, Radiology (diagnostics) ABN Annual Meeting, 17-19 May 2016, The Brighton Centre, Brighton Source Type: research

Effect of Inhaled Corticosteroids in Steroid-Naive COPD Effect of Inhaled Corticosteroids in Steroid-Naive COPD
Explore the impact of inhaled corticosteroids on blood eosinophil levels among COPD patients who have not previously received steroid therapy.BMJ Open Respiratory Research
Source: Medscape Allergy Headlines - November 17, 2016 Category: Allergy & Immunology Tags: Pulmonary Medicine Journal Article Source Type: news

Serum zinc level in bronchial asthma
Conclusion Measurement of zinc level could be recommended in asthmatic adults. proper supplementations of zinc can be useful in the management of asthmatic patients due to increase the effect of antioxidant defense system. However, further multi-centre studies with greater number of patients are needed to warrant the results of this study.
Source: Egyptian Journal of Chest Diseases and Tuberculosis - December 15, 2016 Category: Respiratory Medicine Source Type: research

Inflammatory Bowel Disease in Chronic Granulomatous Disease: an emerging problem over a twenty years ’ experience
ConclusionsPenetrance of CGD‐IBD increases with age. Clinical manifestations may be subtle, and clinicians should have a low threshold to recommend endoscopy. Treatment with NSAIDs and/or steroids achieves a good response, but relapses usually occur. Infection surveillance is mandatory during treatment, in order to prevent opportunistic infections. A close collaboration between Immunologists and Gastroenterologists is pivotal, including combined follow‐up.This article is protected by copyright. All rights reserved.
Source: Pediatric Allergy and Immunology - October 5, 2017 Category: Allergy & Immunology Authors: Giulia Angelino, Paola De Angelis, Simona Faraci, Francesca Rea, Erminia Francesca Romeo, Filippo Torroni, Renato Tambucci, Alessia Claps, Paola Francalanci, Maria Chiriaco, Gigliola Di Matteo, Caterina Cancrini, Paolo Palma, Patrizia D'Argenio, Luigi Dal Tags: Original Source Type: research

P241 Anti-IL5 monoclonal antibodies may provide benefit in asthmatics on chronic oral steroid therapy masking eosinophilia
Current guidelines for the use of anti-IL5 monoclonal antibodies in asthmatics require specified eosinophil counts in the peripheral blood (CBC). Absent eosinophilia in asthmatics on chronic steroid therapy may mask eosinophilic asthma and may not correlate with eosinophils in bronchial fluids and lung tissues.
Source: Annals of Allergy, Asthma and Immunology - October 27, 2017 Category: Allergy & Immunology Authors: R. Tamayev, S. Gupta, A. Rubinstein Source Type: research

Idiopathic nephrotic syndrome.
Abstract Nephrotic syndrome (NS) is defined by massive proteinuria and hypoalbuminemia, with resulting hyperlipidemia and edema. The most common cause of NS in children is idiopathic nephrotic syndrome (INS), also called nephrosis. Its annual incidence has been estimated to 1-4 per 100,000 children and varies with age, race, and geography. Many agents or conditions have been reported to be associated with INS such as infectious diseases, drugs, allergy, vaccinations, and malignancies. The disease may occur during the 1st year of life, but it usually starts between the ages of 2 and 7 years. INS is characteriz...
Source: Archives de Pediatrie - November 20, 2017 Category: Pediatrics Authors: Boyer O, Baudouin V, Bérard E, Dossier C, Audard V, Guigonis V, Vrillon I Tags: Arch Pediatr Source Type: research

Impact of flash glucose monitoring on hypoglycaemia in adults with type 1 diabetes managed with multiple daily injection therapy: a pre-specified subgroup analysis of the IMPACT randomised controlled trial
Conclusions/interpretationUse of flash glucose technology in type 1 diabetes controlled with MDI therapy significantly reduced time in hypoglycaemia without deterioration of HbA1c, and improved treatment satisfaction.Trial registration:ClinicalTrials.gov NCT02232698Funding:Abbott Diabetes Care, Witney, UK
Source: Diabetologia - February 7, 2018 Category: Endocrinology Source Type: research