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Therapy: Immunotherapy
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Total 6127 results found since Jan 2013.
Stinging insect allergy: current perspectives on venom immunotherapy
Sian W Ludman,1 Robert J Boyle2 1Paediatric Allergy Department, St Mary's Hospital, Imperial Healthcare NHS Trust, London, UK; 2Department of Paediatrics, Imperial College London, London, UKAbstract: Systemic allergic reactions to insect stings affect up to 5% of the population during their lifetime, and up to 32% of beekeepers. Such reactions can be fatal, albeit very rarely, and fear of a further systemic reaction (SR) can lead to significant anxiety and quality of life impairment. A recent Cochrane systematic review confirmed that venom immunotherapy (VIT) is an effective treatment for people who have had a systemic...
Source: Journal of Asthma and Allergy - July 22, 2015 Category: Allergy & Immunology Tags: Journal of Asthma and Allergy Source Type: research
Alternative products to treat allergic rhinitis and alternative routes for allergy immunotherapy.
CONCLUSION: There are alternative routes and products to improve the efficacy of immunotherapy.
PMID: 27658026 [PubMed - as supplied by publisher]
Source: American Journal of Rhinology and Allergy - August 31, 2016 Category: ENT & OMF Authors: Ipci K, Oktemer T, Muluk NB, Şahin E, Altıntoprak N, Bafaqeeh SA, Kurt Y, Mladina R, Šubarić M, Cingi C Tags: Am J Rhinol Allergy Source Type: research
Urtica dioica pollen allergy: Clinical, biological, and allergomics analysis.
CONCLUSION: Exposure to nettle pollen can be responsible of allergic symptoms, and several allergens were characterized. Unravelling the allergens of this underestimated allergy might help to improve diagnosis and care for patients, to predict cross-reactivities and design adapted specific immunotherapy.
PMID: 27788883 [PubMed - in process]
Source: Annals of Allergy, Asthma and Immunology - October 31, 2016 Category: Allergy & Immunology Authors: Tiotiu A, Brazdova A, Longé C, Gallet P, Morisset M, Leduc V, Hilger C, Broussard C, Couderc R, Sutra JP, Sénéchal H, Poncet P Tags: Ann Allergy Asthma Immunol Source Type: research
Oral Food Desensitization in Children With IgE-Mediated Cow's Milk Allergy: Immunological Changes Underlying Desensitization.
CONCLUSIONS: The OIT protocol was safe and effective in inducing milk desensitization in 70% of the children with CMA, leading to alterations in their immune profiles toward a nonallergic phenotype.
PMID: 27826960 [PubMed - in process]
Source: Allergy, Asthma and Immunology Research - November 10, 2016 Category: Allergy & Immunology Tags: Allergy Asthma Immunol Res Source Type: research
Allergen-Specific Immunotherapies for Food Allergy.
Authors: Feuille E, Nowak-Wegrzyn A
Abstract
With rising prevalence of food allergy (FA), allergen-specific immunotherapy (AIT) for FA has become an active area of research in recent years. In AIT, incrementally increasing doses of inciting allergen are given with the goal to increase tolerance, initially through desensitization, which relies on regular exposure to allergen. With prolonged therapy in some subjects, AIT may induce sustained unresponsiveness, in which tolerance is retained after a period of allergen avoidance. Methods of AIT currently under study in humans include oral, sublingual, epicutaneous, and ...
Source: Allergy, Asthma and Immunology Research - April 22, 2018 Category: Allergy & Immunology Tags: Allergy Asthma Immunol Res Source Type: research
Allergy immunotherapies for allergic rhinitis: systematic review and assessment of evolving quality.
Conclusions. When as-sessing grass AIT, it is important to focus not only on endpoints but also on the quality of evidence.
PMID: 31187972 [PubMed - as supplied by publisher]
Source: European Annals of Allergy and Clinical Immunology - June 14, 2019 Category: Allergy & Immunology Tags: Eur Ann Allergy Clin Immunol Source Type: research
Insect sting allergy: new guidelines from the European and USA consensus groups: algorithms and recommendations
Purpose of review
Guidelines on insect sting allergy and venom immunotherapy (VIT) have been updated. This review describes the evolution of these guidelines and their similarities and differences.
Recent findings
The US and European guidelines show the evolution of guideline development in the grading of recommendations and the transparency of the evaluation of evidence. The US and European guidelines on VIT are similar in most areas and complimentary in others. The European guidelines are limited to VIT and are based on a published systematic review; the US practice parameters cover all areas of the diagnosis and ma...
Source: Current Opinion in Allergy and Clinical Immunology - August 31, 2019 Category: Allergy & Immunology Tags: ANAPHYLAXIS AND INSECT ALLERGY: Edited by Gianenrico Senna and Mariana Castells Source Type: research
P100 scit in an academic allergy center: a retrospective review
In this study, details of SCIT use at an academic-based allergy clinic is reported after implementation of a new SCIT electronic medical record (EMR).
Source: Annals of Allergy, Asthma and Immunology - October 31, 2019 Category: Allergy & Immunology Authors: M. Tankersley, H. Russell Tags: Allergy Diagnostics and Immunotherapy Source Type: research
Healthcare costs associated with allergic rhinitis, asthma allergy immunotherapy.
This study estimated healthcare costs and utilisation for patients with AR and asthma. Mean annual outpatient visits, pharmaceutical costs and inpatient hospitalisations were calculated for 2010 and 2014, with pharmaceutical and inpatient costs stratified by AIT use. AR and asthma patients had a 35% higher mean number of physician visits and up to 90% higher mean pharmaceutical costs compared to controls. The cost of pharmaceuticals and inpatient hospitalisations were 54% lower in those prescribed AIT. Further research is recommended to understand the reasons for these cost differences.
PMID: 31818082 [PubMed - as supplied by publisher]
Source: European Annals of Allergy and Clinical Immunology - December 12, 2019 Category: Allergy & Immunology Tags: Eur Ann Allergy Clin Immunol Source Type: research
Recent advances in the diagnosis and management of tree nut and seed allergy
Purpose of review
Tree nut (TN) and seed allergies are frequent, and their prevalence appears to be on the rise. Allergic reactions associated with these foods are more frequently severe, and these allergies tend to persist into adulthood, consequently affecting quality of life. In this review, we summarize recent advances in diagnostic modalities and management strategies for TN/seed-allergic patients.
Recent findings
Clinical manifestations of TN and seed allergy range from asymptomatic sensitization to severe anaphylactic reactions. The use of emerging diagnostic tools such as component resolved diagnostics (...
Source: Current Opinion in Allergy and Clinical Immunology - June 1, 2022 Category: Allergy & Immunology Tags: FOOD ALLERGY: Edited by Alessandro Fiocchi and Motohiro Ebisawa Source Type: research
Allergen immunotherapy: clinical and practical education of Italian trainees in allergy and clinical immunology schools.
Authors: Ridolo E, Incorvaia C, Senna GE, Montagni M, Olivieri E, Canonica GW
Abstract
We performed a survey, based on a questionnaire including 20 items, submitted anonymously to Italian trainees in Allergology and Clinical Immunology, in order to obtain information about their specific allergen immunotherapy (AIT) practices. The questionnaire was sent to 40 trainees, who had attended the last two years of the training course. Thirty-four subjects (mean age: 27 years, 65% females) adequately completed the survey. The answers to the questionnaire showed that only 60% of the training programs included lectures on AI...
Source: European Annals of Allergy and Clinical Immunology - June 4, 2015 Category: Allergy & Immunology Tags: Eur Ann Allergy Clin Immunol Source Type: research
Monoclonal antibodies in allergy; updated applications and promising trials.
Authors: Ozdemir C
Abstract
Allergic disorders, as asthma, allergic rhinitis/rhinoconjunctivitis, atopic dermatitis, food allergies and anaphylaxis have an increasing burden in the general population and a growing body of evidence has shown that an increased interest has aroused to seek for more effective treatment strategies. Conventional pharmacotherapy by antihistamines, anti-leukotrienes, corticosteroids and bronchodilators can routinely control most of the cases, in addition to allergen avoidance which saves the date. Furthermore, allergen specific immunotherapy stands as the only curative method to treat the ...
Source: Recent Patents on Inflammation and Allergy Drug Discovery - June 4, 2015 Category: Allergy & Immunology Tags: Recent Pat Inflamm Allergy Drug Discov Source Type: research
For t 2 DNA Vaccine Prevents Forcipomyia taiwana (Biting Midge) Allergy in a Mouse Model
ConclusionsThis study is the first to demonstrate that DNA vaccine encoding midge allergen is effective in preventing allergic skin inflammation induced by biting midge.Immunotherapy using For t 2 DNA vaccine can protect mice from being sensitized by midge allergen and may be a promising treatment for biting midge allergy in the future.This article is protected by copyright. All rights reserved.
Source: Allergy - December 30, 2015 Category: Allergy & Immunology Authors: Mey‐Fann Lee, Pei‐Pong Song, Tzu‐Mei Lin, Yung‐Tsung Chiu, Yi‐Hsing Chen Tags: Original Article: Experimental Allergy and Immunology Source Type: research
Efficacy of a therapeutic treatment using gas‐filled microbubble‐associated phospholipase A2 in a mouse model of honeybee venom allergy
ConclusionsIn contrast to conventional PLA2 subcutaneous immunotherapy, the therapeutic administration of PLA2‐MB treatment to mice that already had established allergy to PLA2 protects all subsequently challenged animals.This article is protected by copyright. All rights reserved.
Source: Allergy - February 6, 2016 Category: Allergy & Immunology Authors: Blaise Corthésy, Anne Lassus, Jacques Terrettaz, François Tranquart, Gilles Bioley Tags: Original Article: Experimental Allergy and Immunology Source Type: research
Dog allergen immunotherapy and allergy to furry animals.
PMID: 27264567 [PubMed - as supplied by publisher]
Source: Annals of Allergy, Asthma and Immunology - May 31, 2016 Category: Allergy & Immunology Authors: Liccardi G, Salzillo A, Calzetta L, Ora J, Rogliani P Tags: Ann Allergy Asthma Immunol Source Type: research
