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Impact of Sodium Zirconium Cyclosilicate Plus Renin-Angiotensin-Aldosterone System Inhibitor Therapy on Short-Term Medical Costs in Hyperkalemia: OPTIMIZE  II Real-World Study
CONCLUSION: RAASi therapy has well-established cardiorenal benefits. In OPTIMIZE II, management of RAASi-induced hyperkalemia with SZC was associated with lower hyperkalemia-related and all-cause medical costs than RAASi discontinuation without SZC, demonstrating medical cost savings with maintaining RAASi therapy with SZC.PMID:37606716 | DOI:10.1007/s12325-023-02631-w
Source: Adv Data - August 22, 2023 Category: Epidemiology Authors: Jamie P Dwyer Abiy Agiro Pooja Desai Yemisi Oluwatosin Source Type: research

Behavioral changes after motivational interviewing versus traditional dental health education in parents of children with high caries risk: Results of a 1-year study
Conclusions: This study found that a single MI intervention changed the reported oral health behaviors better than the traditional approach.
Source: Journal of Indian Society of Pedodontics and Preventive Dentistry - June 25, 2019 Category: Dentistry Authors: Vani Kapoor Anil Gupta Vishal Arya Source Type: research

What Are the Different Types of Myasthenia Gravis?
Discussion Myasthenia gravis (MG) is a problem of the neuromuscular junction which causes muscle weakness. It can occur in all ages and have a range of symptoms from mild localized disease to mortality-threatening respiratory failure. MG occurs in 1.7-30 cases/million, with a prevalence of 77.7 cases/million. Pediatric patients comprise 10-15% of all patients with MG. In various Asian populations, the juvenile MG can be up to 50% of all of the MG cases. Fluctuations in muscle weakness is a hallmark of the disease. As a reminder, “[i]n normal synaptic transmission in the neuromuscular junction, the axon is depolarize...
Source: PediatricEducation.org - February 17, 2020 Category: Pediatrics Authors: Pediatric Education Tags: Uncategorized Source Type: news

Benefits of a Holiday-Specific Nutrition Guide for Individuals With Chronic Kidney Disease
Following the medical nutrition therapy guidelines for a kidney specific diet is important to reduce the risk and progression of chronic kidney disease (CKD) to kidney failure. As CKD progresses, adhering to a kidney diet for individuals with CKD is important to manage symptoms and prevent malnutrition. Nutrition recommendations vary between CKD stages 1-5; however, they all revolve around the same nutrient groups: protein, sodium, potassium, phosphorus, and fats.1 Given that patients will require different quantities of these nutrients, it is crucial to supply them with information that encompasses a wide range of needs.
Source: Journal of Renal Nutrition - May 3, 2020 Category: Urology & Nephrology Authors: Rachel Tetlie, Chilsea Bindosano Tags: Patient Education Source Type: research

Dietary Assessment of Korean Non-dialysis Chronic Kidney Disease Patients with or without Diabetes.
CONCLUSION: DM and kidney function affected energy and nutrient intakes. Subjects in the Late-CKD group consumed less energy than those in the Early-CKD group. Non-DM subjects seemed to restrict protein intake starting from the Early-CKD stage than subjects with DM. Subjects in this study had low energy and high sodium intakes compared with recommended levels. Protein intake was lower in advanced CKD patients, but their intake level was still higher than the recommendation. Dietary intervention strategies for non-dialysis CKD patients need to be customized depending on the presence of DM and kidney function. PMID: 3253...
Source: Journal of Korean Medical Science - June 17, 2020 Category: Biomedical Science Tags: J Korean Med Sci Source Type: research

Lumbriculus variegatus: A novel organism for in vivo pharmacology education
We report the effects of compounds with diverse pharmacodynamic properties onL.variegatus using these assays. The ryanodine receptor antagonist, dantrolene, altered the unstimulated movement ofL.variegatus at 5  μM, whereas stimulated movement was inhibited at ≥25 μM. Lidocaine, a voltage-gated sodium channel blocker, and quinine, a nonselective sodium and potassium channel blocker, reduced both stimulated and unstimulatedL.variegatus movement at ≥0.5 mM. Inhibitory effects of quinine persisted for up to 24 h after drug removal, whereas lidocaine effects were reduced 10 min after drug removal. Herein, we provide...
Source: Pharmacology Research and Perspectives - August 21, 2021 Category: Drugs & Pharmacology Authors: Aidan Seeley, Caitlin Bellamy, Nia A. Davies, Melisa J. Wallace Tags: ORIGINAL ARTICLE Source Type: research

Snacks for the Patient With Chronic Kidney Disease
Nutrition for the patient with chronic kidney disease (CKD) can be complex. Research has shown that nutritional intake can play a significant role in disease progression and includes consideration of dietary sodium, protein, potassium, phosphorus, and calcium. Depending on the phase of CKD, individuals will have different nutrient needs and therefore medical nutrition therapy intervention should be individualized.1 In the 2020 Kidney Disease Quality Initiative Outcomes Clinical Nutrition Guidelines for CKD, the role of the registered dietitian nutritionist with diet individualization was specifically highlighted.
Source: Journal of Renal Nutrition - September 13, 2021 Category: Urology & Nephrology Authors: Stacey Phillips, Sara Flanders Tags: Patient Education Source Type: research

Management of type 2 diabetes in young adults aged 18-30 years: ADS/ADEA/APEG consensus statement
Med J Aust. 2022 Apr 17. doi: 10.5694/mja2.51482. Online ahead of print.ABSTRACTINTRODUCTION: Type 2 diabetes in young adults (nominally, 18-30 years of age) is a more aggressive condition than that seen in older age, with a greater risk of major morbidity and early mortality. This first Australian consensus statement on the management of type 2 diabetes in young adults considers areas where existing type 2 diabetes guidance, directed mainly towards older adults, may not be appropriate or relevant for the young adult population. Where applicable, recommendations are harmonised with current national guidance for type 2 diab...
Source: Medical Journal of Australia - April 17, 2022 Category: General Medicine Authors: Jencia Wong Glynis P Ross Sophia Zoungas Maria E Craig Elizabeth A Davis Kim C Donaghue Louise J Maple-Brown Margaret J McGill Jonathan E Shaw Jane Speight Natalie Wischer Stephen Stranks Source Type: research

Etiopathogenesis of kidney disease in minority populations and an updated special focus on treatment in diabetes and hypertension
J Natl Med Assoc. 2022 May 17:S0027-9684(22)00085-2. doi: 10.1016/j.jnma.2022.05.004. Online ahead of print.ABSTRACTDiabetes and hypertension are the most common causes of chronic kidney disease (CKD) in the general population as well as in the Black and African American population, who also suffer from high rates of CKD and CKD progression compared to the White population. Progression of CKD can lead to kidney failure, and patients with progressive kidney disease have a high risk of premature mortality, particularly from cardiovascular disease. Screening for early detection of CKD is important as it facilitates the initia...
Source: Journal of the National Medical Association - May 19, 2022 Category: General Medicine Authors: Ebele M Umeukeje Jasmine T Washington Susanne B Nicholas Source Type: research

Evaluation and education of hydration and sodium status in a cool environment among Chinese athletes
CONCLUSIONS: The study found that there is a significant difference in sodium levels between gender and seasons. The level of serum osmolality is also significantly different between the whole study populations concerning combined seasons. In this way, many other parameters are evaluated by correlation with seasons and gender. Hence, this study has brought forward various important findings and gives an overall evaluation of hydration status.PMID:36263568 | DOI:10.26355/eurrev_202210_29869
Source: European Review for Medical and Pharmacological Sciences - October 20, 2022 Category: Drugs & Pharmacology Authors: Y-L Fan Z-Y Li Y C Loh Source Type: research