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Malaria Diagnosis Across the International Centers of Excellence for Malaria Research: Platforms, Performance, and Standardization.
Abstract
Diagnosis is "the act of identifying a disease, illness, or problem by examining someone or something." When an individual with acute fever presents for clinical attention, accurate diagnosis leading to specific, prompt treatment often saves lives. As applied to malaria, not only individual patient diagnosis is important but also assessing population-level malaria prevalence using appropriate diagnostic methods is essential for public health purposes. Similarly, identifying (diagnosing) fake antimalarial medications prevents the use of counterfeit drugs that can have disastrous effects. Therefore, accurat...
Source: Am J Trop Med Hyg - August 10, 2015 Category: Infectious Diseases Authors: Kobayashi T, Gamboa D, Ndiaye D, Cui L, Sutton P, Vinetz JM Tags: Am J Trop Med Hyg Source Type: research
HHS: Expand antidiscrimination protections to transgender patients
Transgender patients who receive health care via government programs or funding must receive equal access to treatments and insurance coverage, according to a proposed rule issued Sept. 3 by...
Source: Skin and Allergy News - September 3, 2015 Category: Dermatology Source Type: news
Tunitas Therapeutics Closes $10 Million Series A Financing
Funding to Support Clinical Development of Novel Fusion Protein Therapeutic for Allergy, Asthma
SAN FRANCISCO, Sept. 30, 2015 -- (Healthcare Sales & Marketing Network) -- Tunitas Therapeutics, Inc. today announced the close of a $10 million Series A ve... Biopharmaceuticals, Venture Capital, PersonnelTunitas Therapeutics
Source: HSMN NewsFeed - September 30, 2015 Category: Pharmaceuticals Source Type: news
Just What the Doctor Ordered: Using Parks to Improve Children’s Health
Nate Seltenrich covers science and the environment from Petaluma, CA. His work has appeared in High Country News, Sierra, Yale Environment 360, Earth Island Journal, and other regional and national publications.
Background image: ©ooyo/iStockphoto
About This Article open
Citation: Seltenrich N. 2015. Just what the doctor ordered: using parks to improve children’s health. Environ Health Perspect 123:A254–A259; http://dx.doi.org/10.1289/ehp.123-A254
News Topics: Children’s Health, Climate Change, Green Spaces, Mental Health, Neurologic Health, Noise Pollution, Obesity, Recreation
Published: 1 October ...
Source: EHP Research - September 30, 2015 Category: Environmental Health Authors: Web Admin Tags: Featured Focus News Children's Health Climate Change Green Spaces Mental Health Neurologic Health Noise Pollution Obesity October 2015 Recreation Source Type: research
Applying the 3Rs to asthma research
Asthma remains an area of considerable unmet medical need. Few new drugs have made it to the clinic during the past 50 years, with many that perform well in preclinical animal models of asthma, failing in humans owing to lack of safety and efficacy. The failure to translate promising drug candidates from animal models to humans has led to questions about the utility of in vivo studies and to demand for more predictive models and tools based on the latest technologies.Working with the asthma research community, the UK National Centre for the Replacement, Refinement and Reduction of Animals in Research (NC3Rs; www.nc3rs.org....
Source: European Respiratory Journal - October 30, 2015 Category: Respiratory Medicine Authors: Holmes, A. Tags: 5.3 Allergy and Immunology Source Type: research
Safety, tolerability and potential efficacy of injection of autologous adipose-derived stromal vascular fraction in the fingers of patients with systemic sclerosis: an open-label phase I trial
This study outlines the safety of the autologous SVF cells injection in the hands of patients with SSc. Preliminary assessments at 6 months suggest potential efficacy needing confirmation in a randomised placebo-controlled trial on a larger population.
Funding
GFRS (Groupe Francophone de Recherche sur la Sclérodermie).
Clinical Trials number
NCT01813279.
Source: Annals of the Rheumatic Diseases - November 10, 2015 Category: Rheumatology Authors: Granel, B., Daumas, A., Jouve, E., Harle, J.-R., Nguyen, P.-S., Chabannon, C., Colavolpe, N., Reynier, J.-C., Truillet, R., Mallet, S., Baiada, A., Casanova, D., Giraudo, L., Arnaud, L., Veran, J., Sabatier, F., Magalon, G. Tags: Open access, Immunology (including allergy), Pain (neurology), Connective tissue disease, Epidemiology Clinical and epidemiological research Source Type: research
Short-term administration of disulfiram for reversal of latent HIV infection: a phase 2 dose-escalation study
This study is registered with ClinicalTrials.gov, number NCT01944371. Findings Of 34 participants screened for eligibility at The Alfred Hospital (Melbourne, VIC, Australia), and San Francisco General Hospital (San Francisco, CA, USA), 30 people were enrolled between Sept 24, 2013, and March 31, 2014. The estimated fold increases in cell-associated unspliced HIV RNA from baseline were 1·7 (95% CI 1·3–2·2; p<0·0001) to the timepoint during disulfiram treatment and 2·1 (1·5–2·9; p<0·0001) to the timepoint after disulfiram in the 500 mg group; 1·9 (1·6–2·4; p<0·0001) and 2·5 (1·9–3Â...
Source: The Lancet HIV - November 18, 2015 Category: Infectious Diseases Source Type: research
NIH, CDC get boost in House budget bill
The National Institutes of Health would see an almost 10% increase in funding under a budget deal announced Dec. 15 by House Speaker Paul Ryan (R-Wisc.).
Other provisions in the omnibus budget...
Source: Skin and Allergy News - December 16, 2015 Category: Dermatology Source Type: news
Azithromycin for episodes with asthma-like symptoms in young children aged 1–3 years: a randomised, double-blind, placebo-controlled trial
Publication date: Available online 17 December 2015 Source:The Lancet Respiratory Medicine Author(s): Jakob Stokholm, Bo L Chawes, Nadja H Vissing, ElÃn Bjarnadóttir, Tine M Pedersen, Rebecca K Vinding, Ann-Marie M Schoos, Helene M Wolsk, Sunna Thorsteinsdóttir, Henrik W Hallas, Lambang Arianto, Susanne Schjørring, Karen A Krogfelt, Thea K Fischer, Christian B Pipper, Klaus Bønnelykke, Hans Bisgaard Background Bacteria and viruses are equally associated with the risk of acute episodes of asthma-like symptoms in young children, suggesting antibiotics as a potential treatment for such episodes. We aim...
Source: The Lancet Respiratory Medicine - December 18, 2015 Category: Respiratory Medicine Source Type: research
Budget deal with NIH, CDC funding boost clears Congress
A budget deal that includes increases in funding to both the National Institutes of Health and the Centers for Disease Control and Prevention quickly passed through Congress and is expected to be signed by President Obama.
The <a...
Source: Skin and Allergy News - December 18, 2015 Category: Dermatology Source Type: news
Cancer risk in relatives of patients with a primary disorder of lymphocyte cytotoxicity: a retrospective cohort study
Publication date: December 2015 Source:The Lancet Haematology, Volume 2, Issue 12 Author(s): Alexandra Löfstedt, Samuel C C Chiang, Erik Onelöv, Yenan T Bryceson, Marie Meeths, Jan-Inge Henter Background Mutations in genes for perforin-dependent lymphocyte cytotoxicity are associated with haemophagocytic lymphohistiocytosis, a rare disease of severe hyperinflammation that typically becomes evident in early childhood. It has been suggested that individuals with hypomorphic biallelic mutations in genes associated with haemophagocytic lymphohistiocytosis are at increased risk of developing haematological malignancie...
Source: The Lancet Haematology - January 11, 2016 Category: Hematology Source Type: research
U.S. Scientists Are Starting From Ground Zero With The Zika Vaccine
As the research community gears up to address Zika virus, one common question has been why, if we’ve known about Zika since 1947, are we only starting these efforts in 2016? As Dr. Anthony Fauci, director of the National Institute of Allergy and Infectious Diseases, admitted, the disease is uncharted territory. "We, prior to this time, have really not spent anything on Zika,” he said during a press conference Thursday. Currently, there is no cure and no vaccine for the disease, and diagnosing the disease takes up to two weeks in specialized labs. To ramp up research on the Zika virus threat, the...
Source: Healthy Living - The Huffington Post - January 29, 2016 Category: Consumer Health News Source Type: news
Obama Pitches $1.1 Billion to Fight Opioid, Heroin Addiction
(MedPage Today) -- President's budget includes mandatory funding to get people into treatment
Source: MedPage Today Allergy - February 3, 2016 Category: Allergy & Immunology Source Type: news
Hearing on Emerging Health Threats and the Zika Supplemental Funding Request
U.S. Senate, Committee on Appropriations. 02/11/2016This resource provides a recording of and statements from a two-hour, 10-minute Congressional hearing before the Senate Labor, Health and Human Services, and Education Subcommittee on the Zika outbreak and the supplemental funding request to combat the Zika virus. Witnesses from the Centers for Disease Control and Prevention, and National Institute of Allergy and Infectious Diseases discuss work to accelerate optimal vector control strategies, better diagnostics, and vaccine discovery. (Video or Multimedia)
Source: Disaster Lit: Resource Guide for Disaster Medicine and Public Health - February 13, 2016 Category: Global & Universal Authors: The U.S. National Library of Medicine Source Type: news
Genome-wide expression for diagnosis of pulmonary tuberculosis: a multicohort analysis
Publication date: Available online 20 February 2016 Source:The Lancet Respiratory Medicine Author(s): Timothy E Sweeney, Lindsay Braviak, Cristina M Tato, Purvesh Khatri Background Active pulmonary tuberculosis is difficult to diagnose and treatment response is difficult to effectively monitor. A WHO consensus statement has called for new non-sputum diagnostics. The aim of this study was to use an integrated multicohort analysis of samples from publically available datasets to derive a diagnostic gene set in the peripheral blood of patients with active tuberculosis. Methods We searched two public gene expression mic...
Source: The Lancet Respiratory Medicine - February 20, 2016 Category: Respiratory Medicine Source Type: research
