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Hearing on Emerging Health Threats and the Zika Supplemental Funding Request
U.S. Senate, Committee on Appropriations. 02/11/2016This resource provides a recording of and statements from a two-hour, 10-minute Congressional hearing before the Senate Labor, Health and Human Services, and Education Subcommittee on the Zika outbreak and the supplemental funding request to combat the Zika virus. Witnesses from the Centers for Disease Control and Prevention, and National Institute of Allergy and Infectious Diseases discuss work to accelerate optimal vector control strategies, better diagnostics, and vaccine discovery. (Video or Multimedia)
Source: Disaster Lit: Resource Guide for Disaster Medicine and Public Health - February 12, 2016 Category: Global & Universal Authors: The U.S. National Library of Medicine Source Type: news

Nonallergic Rhinitis
Nonallergic rhinitis (NAR) is one of the most common conditions in medicine, affecting the quality of life of millions of patients throughout the United States. Despite its ubiquitous nature, NAR remains a poorly managed and often difficult to treat condition. NAR is often suboptimally managed by clinicians with poor clinical outcomes. Establishing the correct diagnosis requires a keen understanding of the unique underlying mechanisms involved in NAR, which is still evolving. Ultimately epidemiologic studies that better define NAR prevalence and its economic burden on society are needed to convince funding agencies of the ...
Source: Immunology and Allergy Clinics of North America - March 12, 2016 Category: Allergy & Immunology Authors: Justin Greiwe, Jonathan A. Bernstein Source Type: research

Empirical tuberculosis therapy versus isoniazid in adult outpatients with advanced HIV initiating antiretroviral therapy (REMEMBER): a multicountry open-label randomised controlled trial
Publication date: 19–25 March 2016 Source:The Lancet, Volume 387, Issue 10024 Author(s): Mina C Hosseinipour, Gregory P Bisson, Sachiko Miyahara, Xin Sun, Agnes Moses, Cynthia Riviere, Fredrick K Kirui, Sharlaa Badal-Faesen, David Lagat, Mulinda Nyirenda, Kogieleum Naidoo, James Hakim, Peter Mugyenyi, German Henostroza, Paul D Leger, Javier R Lama, Lerato Mohapi, Jorge Alave, Vidya Mave, Valdilea G Veloso, Sandy Pillay, Nagalingeswaran Kumarasamy, Jing Bao, Evelyn Hogg, Lynne Jones, Andrew Zolopa, Johnstone Kumwenda, Amita Gupta Background Mortality within the first 6 months after initiating...
Source: The Lancet - March 18, 2016 Category: Journals (General) Source Type: research

Windgap Medical raises $3m for epinephrine auto-injector
Windgap Medical said in a regulatory filing today that it raised a debt-and-options round worth $2.9 million for the epinephrine auto-injector it’s developing. Somerville, Mass.-based Windgap is working on a device that would mix a dry formulation of the drug into solution, then inject it into a patient suffering from anaphylaxis due to an acute allergy attack. The device is designed to be smaller than the market leading EpiPen made by Mylan (NSDQ:MYL) and eliminate the shelf life problems associate with liquid epinephrine. The funding round involved 46 unnamed investors, according to the filing. The post Windgap Med...
Source: Mass Device - April 8, 2016 Category: Medical Equipment Authors: Brad Perriello Tags: Drug-Device Combinations Funding Roundup Windgap Medical Source Type: news

U.S. Officials Warn Zika 'Scarier' Than Initially Thought
By Timothy Gardner and Jeff Mason WASHINGTON (Reuters) - Top health officials expressed heightened concern on Monday about the threat posed to the United States by the Zika virus, saying the mosquito that spreads it is now present in about 30 states and hundreds of thousands of infections could appear in Puerto Rico. At a White House briefing, they stepped up pressure on the Republican-led Congress to pass approximately $1.9 billion in emergency funding for Zika preparedness that the Obama administration requested in February. "Everything we look at with this virus seems to be a bit scarier than we initially thought," said...
Source: Healthy Living - The Huffington Post - April 12, 2016 Category: Consumer Health News Source Type: news

Zika Emergency Funding Remains Stalled in Congress
Funding to fight the ongoing Zika virus outbreak remains tied up in bureaucracy as the U.S. Senate adjourned for a week-long recess after hearing arguments over the best way to fund the fight against the virus. “We shouldn’t be taking 10 days off as a dangerous virus threatens this nation,” Senate Minority Leader Harry Reid said, the Atlantic reports. “And it is threatening us.” The White House asked Congress for $1.9 billion in Zika emergency funding in February. Some funds that were allocated to the Ebola response have been repurposed to help with Zika, but health officials argue more is nee...
Source: TIME: Top Science and Health Stories - April 29, 2016 Category: Science Authors: Alexandra Sifferlin Tags: Uncategorized Funding recess Senate Zika Source Type: news

Uptake of antiretroviral therapy and male circumcision after community-based HIV testing and strategies for linkage to care versus standard clinic referral: a multisite, open-label, randomised controlled trial in South Africa and Uganda
Publication date: May 2016 Source:The Lancet HIV, Volume 3, Issue 5 Author(s): Ruanne V Barnabas, Heidi van Rooyen, Elioda Tumwesigye, Justin Brantley, Jared M Baeten, Alastair van Heerden, Bosco Turyamureeba, Philip Joseph, Meighan Krows, Katherine K Thomas, Torin T Schaafsma, James P Hughes, Connie Celum Background Male circumcision decreases HIV acquisition by 60%, and antiretroviral therapy (ART) almost eliminates HIV transmission from HIV-positive people who are virally suppressed; however, coverage of these interventions has lagged behind targets. We aimed to assess whether community-based HIV testing ...
Source: The Lancet HIV - April 30, 2016 Category: Infectious Diseases Source Type: research

Retention in care during the first 3 years of antiretroviral therapy for women in Malawi's option B+ programme: an observational cohort study
We examined loss to follow-up and retention in care in patients in the option B+ programme during their first 3 years on ART. Methods We analysed two data sources: aggregated facility-level data about patients in option B+ who started ART between Oct 1, 2011, and June 30, 2012, at 546 health facilities; and patient-level data from 20 large facilities with electronic medical record system for HIV-positive women who started ART between Sept 1, 2011, and Dec 31, 2013, under option B+ or because they had WHO clinical stages 3 or 4 disease or had CD4 counts of less than 350 cells per μL. We used facility-level data to calcula...
Source: The Lancet HIV - April 30, 2016 Category: Infectious Diseases Source Type: research

Researchers Find Alternative Pathways to HIV Antibodies
Contact: Sarah Avery Phone: 919-660-1306 Email: sarah.avery@duke.edu https://www.dukehealth.org FOR IMMEDIATE RELEASE on Tuesday, May 3, 2016 DURHAM, N.C. – The immune system appears to hamper an investigational vaccine from inducing antibodies that protect against HIV infection, but there may be ways to overcome this impediment, according to research led by the Duke Human Vaccine Institute. Using mouse and monkey models, the researchers showed they could could identify the roadblocks to inducing the broadly neutralizing antibodies that are considered imperative for successful protection against infection.  They then fo...
Source: DukeHealth.org: Duke Health Features - May 3, 2016 Category: Pediatrics Tags: Duke Medicine Source Type: news

House Republicans Are Happy To Dither As Zika Threat Looms
Public health officials are growing more and more concerned about the Zika virus as its true impact in South and Central America becomes clear. In January, the World Health Organization said Zika could be on the verge of spreading throughout the Americas. Health organizations in the U.S. are upping their efforts to develop a vaccine and eradicate the virus, and the White House has asked that money be appropriated to help make this happen. But as certain as death and taxes, Republicans in the House of Representatives have emerged to slow this process to a crawl. GOP lawmakers have met these calls to action with indifference...
Source: Science - The Huffington Post - May 5, 2016 Category: Science Source Type: news

D.C. Week: House, Senate Split on Zika Funding
(MedPage Today) -- Also, SCOTUS punts on Affordable Care Act birth control coverage issue
Source: MedPage Today Allergy - May 21, 2016 Category: Allergy & Immunology Source Type: news

NIAID funding to Jackson Laboratory researcher to investigate chronic fatigue syndrome
(Jackson Laboratory) Professor Derya Unutmaz, M.D., of The Jackson Laboratory for Genomic Medicine, will receive five years of funding -- totaling $3,281,515 from the National Institute of Allergy and Infectious Diseases -- to find better ways to diagnose and treat myalgic encephalomyelitis, the debilitating and mysterious condition more generally known as chronic fatigue syndrome.
Source: EurekAlert! - Medicine and Health - June 7, 2016 Category: Global & Universal Source Type: news

Zika Sex Research Begins Despite U.S. Congress Funding ImpasseZika Sex Research Begins Despite U.S. Congress Funding Impasse
It could take years to learn how long men infected with Zika are capable of sexually transmitting the virus, which can cause crippling birth defects and other serious neurological disorders. Reuters Health Information
Source: Medscape Allergy Headlines - July 1, 2016 Category: Allergy & Immunology Tags: Infectious Diseases News Source Type: news

NIH expands investment in HIV cure research
(NIH/National Institute of Allergy and Infectious Diseases) NIH has awarded approximately $30 million in annual funding over the next five years to six research collaborations working to advance basic medical science toward an HIV cure. The awards comprise the second iteration of the Martin Delaney Collaboratory: Towards an HIV-1 Cure program and are a part of President Barack Obama's pledge to invest in HIV cure research.
Source: EurekAlert! - Medicine and Health - July 13, 2016 Category: Global & Universal Source Type: news

UAB research team awarded $11.5M contract
A group of researchers at the University of Alabama at Birmingham was recently awarded an $11.5 million contract to study treatment of babies born with congenital cytomegalovirus and frequency of neonatal herpes infections in the United States and Peru. The National Institute of Allergy and Infectious Disease awarded the funding to the UAB Department of Pediatrics to support two studies slated to be conducted at UAB and its partner academic sites. Nearly 1 percent of babies born in the United States…
Source: bizjournals.com Health Care:Pharmaceuticals headlines - July 15, 2016 Category: Pharmaceuticals Authors: Tim Steere Source Type: news